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    Pesticidal genes and methods of use
    1.
    发明授权
    Pesticidal genes and methods of use 有权

    公开(公告)号：US11898153B2

    公开(公告)日：2024-02-13

    申请号：US17398575

    申请日：2021-08-10

    申请人： AgBiome, Inc.

    发明人： Jessica Parks ,  Kira Bulazel Roberts ,  Rebecca E. Thayer

    IPC分类号： C12N15/82 ,  C07K14/195 ,  A01N37/46 ,  C07K14/32 ,  A01N63/50 ,  C07K14/325

    CPC分类号： C12N15/8286 ,  A01N37/46 ,  A01N63/50 ,  C07K14/195 ,  C07K14/32 ,  C07K14/325 ,  C12N15/8261 ,  C12N15/8285 ,  Y02A40/146

    摘要： Compositions having pesticidal activity and methods for their use are provided. Compositions include isolated and recombinant polypeptides having pesticidal activity, recombinant and synthetic nucleic acid molecules encoding the polypeptides, DNA constructs and vectors comprising the nucleic acid molecules, host cells comprising the vectors, and antibodies to the polypeptides. Polynucleotide sequences encoding the polypeptides can be used in DNA constructs or expression cassettes for transformation and expression in organisms of interest. The compositions and methods provided are useful for producing organisms with enhanced pest resistance or tolerance. Transgenic plants and seeds comprising a nucleotide sequence that encodes a pesticidal protein of the invention are also provided. Such plants are resistant to insects and other pests. Methods are provided for producing the various polypeptides disclosed herein, and for using those polypeptides for controlling or killing a pest. Methods and kits for detecting polypeptides of the invention in a sample are also included.

    AXMI115 VARIANT INSECTICIDAL GENE AND METHODS FOR ITS USE
    5.
    发明申请
    AXMI115 VARIANT INSECTICIDAL GENE AND METHODS FOR ITS USE 审中-公开

    公开(公告)号：US20180251780A1

    公开(公告)日：2018-09-06

    申请号：US15960817

    申请日：2018-04-24

    申请人： ATHENIX CORP.

    发明人： Nalini Manoj Desai ,  Volker Heinrichs ,  Duane Lehtinen

    IPC分类号： C12N15/82 ,  C07K14/325 ,  A01N37/44 ,  A01N63/02 ,  C07K14/32

    CPC分类号： C12N15/8286 ,  A01N37/44 ,  A01N63/02 ,  C07K14/32 ,  C07K14/325 ,  C07K2319/00 ,  C07K2319/24 ,  C12N15/8279 ,  C12N15/8285 ,  Y02A40/162

    摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. The toxin coding sequences can be used in DNA constructs or expression cassettes for expression in plants and bacteria. Compositions include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, polynucleotide sequences and the toxin proteins encoded thereby are provided. Also provided are antibodies specifically binding to those amino acid sequences. In particular, the invention encompasses nucleotide sequences encoding fusion proteins, as well as biologically active variants and fragments thereof, wherein the fusion protein contains the C-terminal portion of SEQ ID NO:43. The fusion protein may also contain the N-terminal portion of SEQ ID NO:45. The invention also includes the nucleotide sequence of SEQ ID NO:47 and 1-14, or a nucleotide sequence encoding the amino acid sequence set forth in SEQ ID NO:2, 3, 7-14 and 47, including biologically active variants and fragments thereof.