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公开(公告)号:US11643681B2
公开(公告)日:2023-05-09
申请号:US15917384
申请日:2018-03-09
申请人: TAKARA BIO USA, INC.
发明人: Victor Joseph , Amjad Huda , Alnoor Shivji
CPC分类号: C12Q1/686 , B01L7/525 , B01L7/5255 , G01N21/253 , B01L7/54 , B01L2200/10 , B01L2200/147 , B01L2300/0654 , B01L2300/0819 , B01L2300/0829 , B01L2300/0893 , B01L2300/1805 , B01L2300/1827 , B01L2300/1844 , B01L2300/1894 , G01N21/0332
摘要: Apparatus, systems, chips, and methods of performing a large number of simultaneous chemical reactions are provided herein. The chips of the invention comprise addressable units that can be addressed according to the temperature of the reaction to be run. The subject apparatus, systems, and chips are particularly suited for performing polymerase chain reactions on thousands of nucleic acid sequences, up to and including sequences of an entire genuine of an organism of interest.
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公开(公告)号:US11642023B2
公开(公告)日:2023-05-09
申请号:US17365483
申请日:2021-07-01
发明人: Robert Vince , Swati Sudhakar More
IPC分类号: G01J3/28 , A61B3/12 , G01N21/31 , G01J3/00 , G01J3/40 , G01N21/25 , A61B3/14 , A61K38/06 , G01N33/50 , A61B5/00
CPC分类号: A61B3/12 , A61B3/14 , A61B5/4848 , A61K38/063 , G01J3/00 , G01J3/28 , G01J3/40 , G01N21/25 , G01N21/31 , G01N33/5038
摘要: Described herein is the use of a visible near infrared (VNIR) hyperspectral imaging system as a non-invasive diagnostic tool for early detection of Alzheimer's disease (AD). Also described herein is the use of a VNIR hyperspectral imaging system in high throughput screening of potential therapeutics against AD.
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公开(公告)号:US20230122147A1
公开(公告)日:2023-04-20
申请号:US17874091
申请日:2022-07-26
发明人: Adyary Fallarero , Marika J. Raitio , Tommi Suvanto , Katja Eklin
IPC分类号: G01N21/25
摘要: The method of analyzing absorbance of one or more liquid samples (3) arranged in the wells (2) of a microplate (1) comprises the steps of setting a desired wavelength falling within the wavelength range of 380 nm-750 nm for absorbance measurement (101), illuminating the samples (3) using electromagnetic radiation having a bandwidth of at most 20 nm around the set wavelength (102), measuring radiant flux transmitted through each sample (3) (103), on the basis of measured radiant flux values, determining an absorbance value for each sample (3) (104), and visualizing the absorbance values on a display (12) as a matrix comprising a plurality of cells (23), each cell (23) corresponding to a well (2) of the microplate (1) (105). The set wavelength is used as an input for determining the visual properties of the cells (23).
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公开(公告)号:US20230120417A1
公开(公告)日:2023-04-20
申请号:US18082992
申请日:2022-12-16
发明人: Greg Yantz , Don Straus , Gordon Siek , Damon Dehart
IPC分类号: B01L3/00 , A61B5/157 , G01N21/03 , G01N21/25 , G01N21/64 , G01N33/543 , A61B5/15 , A61B5/151
摘要: The invention provides devices that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient detection of individual microscopic targets at low magnification for highly sensitive testing. The invention does not require washing steps and thus allows sensitive and specific detection while simplifying manual operation and lowering costs and complexity in automated operation. In short, the invention provides devices that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests.
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公开(公告)号:US20230116586A1
公开(公告)日:2023-04-13
申请号:US17944205
申请日:2022-09-14
申请人: Tetsumaru FUJITA , Hidetaka NOGUCHI
发明人: Tetsumaru FUJITA , Hidetaka NOGUCHI
摘要: An electronic device includes a housing that houses a movable member inside the housing, and a shock absorbing member that reduces a shock to the movable member. The shock absorbing member holds the housing on an inner side of the shock absorbing member and includes at least one of a protrusion protruding in a direction along a movable direction of the movable member or a depression depressed in a direction along the movable direction on an outer side of the shock absorbing member.
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公开(公告)号:US20230113897A1
公开(公告)日:2023-04-13
申请号:US18045695
申请日:2022-10-11
申请人: Shrenik Deliwala
发明人: Shrenik Deliwala
摘要: Modulation-encoded light, using different spectral bin coded light components, can illuminate a stationary or moving (relative) target object or scene. Response signal processing can use information about the respective different time-varying modulation functions, to decode to recover information about a respective response parameter affected by the target object or scene. Electrical or optical modulation encoding can be used. LED-based spectroscopic analysis of a composition of a target (e.g., SpO2, glucose, etc.) can be performed; such can optionally include decoding of encoded optical modulation functions. Baffles or apertures or optics can be used, such as to constrain light provided by particular LEDs. Coded light illumination can be used with a focal plane array light imager receiving response light for inspecting a moving semiconductor or other target. Encoding can use orthogonal functions, such as an RGB illumination sequence, or a sequence of combinations of spectrally contiguous or non-contiguous colors.
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公开(公告)号:US11624701B2
公开(公告)日:2023-04-11
申请号:US17410633
申请日:2021-08-24
IPC分类号: G01N21/25 , D06F34/18 , D06F58/36 , D06F103/02 , D06F105/48 , D06F103/06 , D06F103/04 , D06F105/56 , D06F105/38 , D06F105/24 , D06F105/20
摘要: The invention relates to a laundry treating appliance and method for controlling the operation of the laundry treating appliance by determining the surface area of the laundry based on image data of the laundry.
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公开(公告)号:US11614695B2
公开(公告)日:2023-03-28
申请号:US17393071
申请日:2021-08-03
发明人: Ryuichi Araki
摘要: An image forming apparatus includes an optical sensor configured to detect an image formed on an intermediate transfer belt. The optical sensor includes a first light emitting diode (LED), a second LED, a first photodiode (PD), and a second PD on a substrate. The first PD is arranged at a position at which specularly reflected light of light emitted from the first LED can be received, and scattered reflected light of light emitted from the second LED can be received. The second PD is arranged at a position at which scattered reflected light of light emitted from the second LED can be received. A light receiving surface of the first PD and a light receiving surface of the second PD are formed at different angles. The light receiving surface of the first PD has an area that is smaller than an area of the light receiving surface of the second PD.
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公开(公告)号:US11604148B2
公开(公告)日:2023-03-14
申请号:US16483729
申请日:2018-02-09
申请人: Essenlix Corporation
发明人: Stephen Y. Chou , Wei Ding , Yufan Zhang , Ji Qi
摘要: A device and a method of using the device for improving sensitivity, speed, and easy-to-use of a colorimetric assay of a liquid sample are provided. The device includes a first plate and a second plate, spacers, and a textured surface. The two plates each have a sample contact surface and are movable relative to each other into an open configuration or a closed configuration. The sample is deposited on one or both plates in the open configuration. Thereafter, the closed configuration is formed where the plates compress at least part of the deposited sample into a continuous layer. The textured surface is disposed on the sample contact surface of the second plate and has a textured structure that scatters light, from which an optical signal such as a colorimetric or fluorescent signal can be obtained for analyzing the sample.
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公开(公告)号:US20230074949A1
公开(公告)日:2023-03-09
申请号:US17767865
申请日:2020-10-09
申请人: Fenghua LIU
发明人: Fenghua LIU
摘要: The title of the invention is the remote sensing of physiological dynamics electromagnetic big data, the related technology belongs to the field of remote sensing of physiology or psychology. The technical problem to be solved by the present invention is the remote sensing of physiological or psychological electromagnetic dynamics of human, animal or plant individuals, the related electromagnetic media could be nucleon, electron, atom, molecule, ion, water, fluid, blood, DNA, RNA, amino acid, sugar, fat, protein, cell, tissue, organ, bone, fruit, flower, leave, stem, bark, and root, etc., the 30 μm-1000 million meters band electromagnetic waves could be used to extract the reflection spectra of partial or entire human, animal or plant individual electromagnetic media in different physiology or psychology states, single or multiple sensitive wavelengths or wavebands of spectrum troughs could be chosen as the electromagnetic wave probes, which could be used to irradiate partial or entire human, animal or plant individual electromagnetic media and extract the reflection waves, the electromagnetic dynamics of the human, animal or plant individuals in different physiology or psychology states could be transformed to the different electromagnetic indexes, such as the frequency, reflection rate and phase values, the major applications of the invention might be the drunk driving, fatigue driving, road rage driving, big data and big ecology, etc.
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