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公开(公告)号：US20200299751A1
公开(公告)日：2020-09-24
申请号：US16896830
申请日：2020-06-09
申请人： Takara Bio USA, Inc.
发明人： Victor Joseph , Amjad Huda , Alnoor Shivji , Jie Zhou
IPC分类号： C12Q1/686 , B01L3/00 , B01L7/00 , B82Y30/00 , C12Q1/6844 , G01N21/64 , G01N35/00 , G01N21/03 , C12Q1/6806 , G01N21/01 , H01L27/144 , H01L31/0203 , H01L31/0232 , H01L31/024 , H01L31/105 , H01L31/18
摘要： The present invention provides miniaturized instruments for conducting chemical reactions where control of the reaction temperature is desired or required. Specifically, this invention provides chips and optical systems for performing and monitoring temperature-dependent chemical reactions. The apparatus and methods embodied in the present invention are particularly useful for high-throughput and low-cost amplification of nucleic acids.
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公开(公告)号：US11643681B2
公开(公告)日：2023-05-09
申请号：US15917384
申请日：2018-03-09
申请人： TAKARA BIO USA, INC.
发明人： Victor Joseph , Amjad Huda , Alnoor Shivji
CPC分类号： C12Q1/686 , B01L7/525 , B01L7/5255 , G01N21/253 , B01L7/54 , B01L2200/10 , B01L2200/147 , B01L2300/0654 , B01L2300/0819 , B01L2300/0829 , B01L2300/0893 , B01L2300/1805 , B01L2300/1827 , B01L2300/1844 , B01L2300/1894 , G01N21/0332
摘要： Apparatus, systems, chips, and methods of performing a large number of simultaneous chemical reactions are provided herein. The chips of the invention comprise addressable units that can be addressed according to the temperature of the reaction to be run. The subject apparatus, systems, and chips are particularly suited for performing polymerase chain reactions on thousands of nucleic acid sequences, up to and including sequences of an entire genuine of an organism of interest.
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公开(公告)号：US10718014B2
公开(公告)日：2020-07-21
申请号：US15870247
申请日：2018-01-12
申请人： Takara Bio USA, Inc.
发明人： Victor Joseph , Amjad Huda , Alnoor Shivji , Jie Zhou
IPC分类号： C12Q1/686 , B01L3/00 , B01L7/00 , B82Y30/00 , C12Q1/6844 , G01N21/64 , G01N35/00 , G01N21/03 , C12Q1/6806 , G01N21/01 , H01L27/144 , H01L31/0203 , H01L31/0232 , H01L31/024 , H01L31/105 , H01L31/18 , G01N21/76 , G01N35/04
摘要： The present invention provides miniaturized instruments for conducting chemical reactions where control of the reaction temperature is desired or required. Specifically, this invention provides chips and optical systems for performing and monitoring temperature-dependent chemical reactions. The apparatus and methods embodied in the present invention are particularly useful for high-throughput and low-cost amplification of nucleic acids.
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公开(公告)号：US09909171B2
公开(公告)日：2018-03-06
申请号：US14857379
申请日：2015-09-17
申请人： Takara Bio USA, Inc.
发明人： Victor Joseph , Amjad Huda , Alnoor Shivji , Jie Zhou
IPC分类号： C12Q1/68 , B01L3/00 , B01L7/00 , B82Y30/00 , G01N21/03 , G01N35/00 , G01N21/01 , H01L27/144 , H01L31/0203 , H01L31/0232 , H01L31/024 , H01L31/105 , H01L31/18 , G01N21/64 , G01N21/76 , G01N35/04
CPC分类号： C12Q1/686 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L7/54 , B01L2200/0689 , B01L2300/044 , B01L2300/0636 , B01L2300/0654 , B01L2300/0819 , B01L2300/0829 , B01L2300/18 , B01L2300/1822 , B01L2300/1827 , B82Y30/00 , C12Q1/6806 , C12Q1/6844 , G01N21/01 , G01N21/0332 , G01N21/6408 , G01N21/6452 , G01N21/76 , G01N35/0099 , G01N2021/6417 , G01N2021/6484 , G01N2035/0405 , G01N2201/0231 , H01L27/1443 , H01L31/0203 , H01L31/02325 , H01L31/024 , H01L31/105 , H01L31/18 , C12Q2565/501
摘要： The present invention provides miniaturized instruments for conducting chemical reactions where control of the reaction temperature is desired or required. Specifically, this invention provides chips and optical systems for performing and monitoring temperature-dependent chemical reactions. The apparatus and methods embodied in the present invention are particularly useful for high-throughput and low-cost amplification of nucleic acids.
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公开(公告)号：US20180201978A1
公开(公告)日：2018-07-19
申请号：US15917384
申请日：2018-03-09
申请人： TAKARA BIO USA, INC.
发明人： Victor Joseph , Amjad Huda , Alnoor Shivji
CPC分类号： C12Q1/686 , B01L7/525 , B01L7/5255 , B01L7/54 , B01L2200/10 , B01L2200/147 , B01L2300/0654 , B01L2300/0819 , B01L2300/0829 , B01L2300/0893 , B01L2300/1805 , B01L2300/1827 , B01L2300/1844 , B01L2300/1894 , G01N21/0332 , G01N21/253
摘要： Apparatus, systems, chips, and methods of performing a large number of simultaneous chemical reactions are provided herein. The chips of the invention comprise addressable units that can be addressed according to the temperature of the reaction to be run. The subject apparatus, systems, and chips are particularly suited for performing polymerase chain reactions on thousands of nucleic acid sequences, up to and including sequences of an entire genuine of an organism of interest.
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公开(公告)号：US20180135107A1
公开(公告)日：2018-05-17
申请号：US15870290
申请日：2018-01-12
申请人： Takara Bio USA, Inc.
发明人： Victor Joseph , Amjad Huda , Alnoor Shivji , Jie Zhou
IPC分类号： C12Q1/686 , H01L27/144 , B01L3/00 , G01N21/01 , H01L31/18 , H01L31/0203 , H01L31/0232 , H01L31/024 , H01L31/105 , C12Q1/6806
CPC分类号： C12Q1/686 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L7/54 , B01L2200/0689 , B01L2300/044 , B01L2300/0636 , B01L2300/0654 , B01L2300/0819 , B01L2300/0829 , B01L2300/18 , B01L2300/1822 , B01L2300/1827 , B82Y30/00 , C12Q1/6806 , C12Q1/6844 , G01N21/01 , G01N21/0332 , G01N21/6408 , G01N21/6452 , G01N21/76 , G01N35/0099 , G01N2021/6417 , G01N2021/6484 , G01N2035/0405 , G01N2201/0231 , H01L27/1443 , H01L31/0203 , H01L31/02325 , H01L31/024 , H01L31/105 , H01L31/18 , C12Q2565/501
摘要： The present invention provides miniaturized instruments for conducting chemical reactions where control of the reaction temperature is desired or required. Specifically, this invention provides chips and optical systems for performing and monitoring temperature-dependent chemical reactions. The apparatus and methods embodied in the present invention are particularly useful for high-throughput and low-cost amplification of nucleic acids.
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公开(公告)号：US20180135106A1
公开(公告)日：2018-05-17
申请号：US15870247
申请日：2018-01-12
申请人： Takara Bio USA, Inc.
发明人： Victor Joseph , Amjad Huda , Alnoor Shivji , Jie Zhou
IPC分类号： C12Q1/686 , H01L27/144 , B01L3/00 , G01N21/01 , H01L31/18 , H01L31/0203 , H01L31/0232 , H01L31/024 , H01L31/105 , C12Q1/6806
CPC分类号： C12Q1/686 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L7/54 , B01L2200/0689 , B01L2300/044 , B01L2300/0636 , B01L2300/0654 , B01L2300/0819 , B01L2300/0829 , B01L2300/18 , B01L2300/1822 , B01L2300/1827 , B82Y30/00 , C12Q1/6806 , C12Q1/6844 , G01N21/01 , G01N21/0332 , G01N21/6408 , G01N21/6452 , G01N21/76 , G01N35/0099 , G01N2021/6417 , G01N2021/6484 , G01N2035/0405 , G01N2201/0231 , H01L27/1443 , H01L31/0203 , H01L31/02325 , H01L31/024 , H01L31/105 , H01L31/18 , C12Q2565/501
摘要： The present invention provides miniaturized instruments for conducting chemical reactions where control of the reaction temperature is desired or required. Specifically, this invention provides chips and optical systems for performing and monitoring temperature-dependent chemical reactions. The apparatus and methods embodied in the present invention are particularly useful for high-throughput and low-cost amplification of nucleic acids.
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公开(公告)号：US09951381B2
公开(公告)日：2018-04-24
申请号：US14853480
申请日：2015-09-14
申请人： Takara Bio USA, Inc.
发明人： Victor Joseph , Amjad Huda , Alnoor Shivji
CPC分类号： C12Q1/686 , B01L7/525 , B01L7/5255 , B01L7/54 , B01L2200/10 , B01L2200/147 , B01L2300/0654 , B01L2300/0819 , B01L2300/0829 , B01L2300/0893 , B01L2300/1805 , B01L2300/1827 , B01L2300/1844 , B01L2300/1894 , G01N21/0332 , G01N21/253
摘要： Apparatus, systems, chips, and methods of performing a large number of simultaneous chemical reactions are provided herein. The chips of the invention comprise addressable units that can be addressed according to the temperature of the reaction to be run. The subject apparatus, systems, and chips are particularly suited for performing polymerase chain reactions on thousands of nucleic acid sequences, up to and including sequences of an entire genome of an organism of interest.
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