METHOD AND APPARATUS FOR DISRUPTING CELLS AND AMPLIFYING NUCLEIC ACIDS USING GOLD NANORODS
    91.
    发明申请
    METHOD AND APPARATUS FOR DISRUPTING CELLS AND AMPLIFYING NUCLEIC ACIDS USING GOLD NANORODS 有权
    破坏细胞的方法和装置,使用金纳多糖放大核酸

    公开(公告)号:US20110212514A1

    公开(公告)日:2011-09-01

    申请号:US13107677

    申请日:2011-05-13

    IPC分类号: C12M1/00 C12M1/02 C12M1/42

    摘要: Provided is a method of disrupting cells comprising adding gold nanorods to a solution containing cells and irradiating the gold nanorods with a laser to disrupt the cells. A method and an apparatus for continuously disrupting cells and amplifying nucleic acids in a single microchamber are also provided, wherein the method comprises introducing a solution containing cells and gold nanorods into a microchamber, irradiating a laser onto the gold nanorods to disrupt the cells, and amplifying a nucleic acid from the disrupted cells in the microchamber.

    摘要翻译: 提供一种破坏细胞的方法,包括向含有细胞的溶液中加入金纳米棒并用激光照射金纳米棒以破坏细胞。 还提供了用于在单个微室中连续破坏细胞和扩增核酸的方法和装置,其中所述方法包括将含有细胞和金纳米棒的溶液引入微室中,将激光照射到金纳米棒上以破坏细胞,以及 在微室中从破碎的细胞中扩增核酸。

    APPARATUS FOR ANALYZING SAMPLE
    93.
    发明申请
    APPARATUS FOR ANALYZING SAMPLE 有权
    用于分析样品的装置

    公开(公告)号:US20110176963A1

    公开(公告)日:2011-07-21

    申请号:US13007192

    申请日:2011-01-14

    IPC分类号: G01N33/48

    摘要: A apparatus for analyzing sample to prevent a sample from being stuck to a surface of the apparatus for analyzing sample in the course of being injected into the apparatus for analyzing sample. The apparatus for analyzing sample includes a platform having a disk shape. The platform includes chambers and channels, a sample inlet hole which is formed in an outer surface the platform and through which a sample is injected into the platform; an opening which is formed in the outer surface of the platform and through which a residual of the sample, present on the outer surface of the platform around the sample inlet hole, is introduced into a receiving space isolated from the chambers and channels; and a barrier which is formed on the outer surface of the platform around a portion of the opening to prevent the residual of the sample from moving past the opening in a radial outward direction of the platform.

    摘要翻译: 一种用于分析样品以防止样品被粘附到用于分析样品的装置的表面以在被注入到用于分析样品的装置中的过程中的装置。 用于分析样品的装置包括具有盘形状的平台。 平台包括室和通道,样品入口孔,其形成在平台的外表面中,样品通过该入口孔注入平台; 形成在平台的外表面中的开口,其中存在于围绕样品入口孔的平台的外表面上的样品的残留物被引入到与腔室和通道隔离的接收空间中; 以及围绕所述开口的一部分形成在所述平台的外表面上以防止所述样品的残留物沿所述平台的径向向外方向移动经过所述开口的障碍物。

    VALVE UNIT, MICROFLUIDIC DEVICE HAVING THE SAME, AND METHOD OF DRIVING THE VALVE UNIT
    95.
    发明申请
    VALVE UNIT, MICROFLUIDIC DEVICE HAVING THE SAME, AND METHOD OF DRIVING THE VALVE UNIT 有权
    阀组,具有该阀单元的微流体装置以及驱动阀单元的方法

    公开(公告)号:US20110100476A1

    公开(公告)日:2011-05-05

    申请号:US12938777

    申请日:2010-11-03

    IPC分类号: F16K31/00

    摘要: A normally open valve unit to close a channel, a microfluidic device equipped with the same, and a method of driving the valve unit are provided. The valve unit includes a valve substance including a phase transition material, a valve substance chamber which communicates with the channel and in which the valve substance is disposed, and a fusion structure formed in a section of the channel in which ,wherein when the valve substance contained in the valve substance chamber is fused by applied energy and flows into the section of the channel in which the fusion structure is formed, and the valve substance is heated to melt the fusion structure and conduct fused bonding of the channel, thereby closing the channel.

    摘要翻译: 设置关闭通道的常开阀单元,配备有该通道的微流体装置以及驱动阀单元的方法。 所述阀单元包括阀体,所述阀体包括相变材料,与所述通道连通并且所述阀体配置的阀体室,以及形成在所述通道的一部分中的熔融结构,其中当所述阀体 阀体物质室中所含的气体被施加的能量熔化并流入其中形成熔融结构的通道的部分,并且阀体被加热以融化熔融结构并导通通道的熔合,从而封闭通道 。

    Centrifugal force-based microfluidic device for protein detection and microfluidic system including the same
    96.
    发明授权
    Centrifugal force-based microfluidic device for protein detection and microfluidic system including the same 有权
    用于蛋白质检测和微流体系统的基于离心力的微流体装置包括相同的

    公开(公告)号:US07776267B2

    公开(公告)日:2010-08-17

    申请号:US11850129

    申请日:2007-09-05

    IPC分类号: G01N9/30

    摘要: A centrifugal force-based microfluidic device for the detection of a target biomolecule and a microfluidic system including the same are provided. The device includes a body of revolution; a microfluidic structure disposed in the body of revolution including chambers, channels connecting the chambers, and valves disposed in the channels to control fluid flow, the microfluidic structures transmitting fluid using centrifugal force due to rotation of the body of revolution; and beads disposed in the microfluidic structures, the beads having capture probes on the surfaces thereof which are selectively bonded with target protein; and a detection probe disposed in the microfluidic structures and selectively bonded to the target protein, and which includes a material required to express an optical signal, wherein the microfluidic structure mixes the beads, biological samples, and the detection probe to react and washes and separates the beads after the reaction.

    摘要翻译: 提供了用于检测靶生物分子的离心力微流体装置和包括其的微流体系统。 该装置包括一个革命体; 设置在旋转体中的微流体结构,包括腔室,连接腔室的通道,以及设置在通道中的阀,以控制流体流动,微流体结构由于旋转体旋转而使用离心力传送流体; 和珠子,其设置在微流体结构中,珠粒在其表面上具有与靶蛋白质选择性结合的捕获探针; 以及设置在微流体结构中并选择性地结合到靶蛋白上并且包括表达光信号所需的材料的检测探针,其中微流体结构混合珠,生物样品和检测探针以反应和洗涤和分离 反应后的珠子。

    MICROFLUIDIC VALVE FILLER AND VALVE UNIT INCLUDING THE SAME
    100.
    发明申请
    MICROFLUIDIC VALVE FILLER AND VALVE UNIT INCLUDING THE SAME 有权
    微型阀门填充阀和阀门单元包括它们

    公开(公告)号:US20080187474A1

    公开(公告)日:2008-08-07

    申请号:US12027290

    申请日:2008-02-07

    IPC分类号: B01J19/00 C09K3/10 H01F1/00

    摘要: Provided are a valve filler and a valve unit including the valve filler. The valve filler includes: a phase transition material; and a heating fluid comprising a carrier oil and a plurality of micro heating particles suspended in the carrier oil, the heating fluid being mixed with the phase transition material, wherein, when external energy is supplied, the micro heating particles receive the external energy and generate heat to melt the phase transition material into a fluid state, and when no external energy is supplied, the phase transition material hardens into a solid state.

    摘要翻译: 提供了一种阀填料和包括阀填料的阀单元。 阀填料包括:相变材料; 以及加热流体,其包含载体油和悬浮在载体油中的多个微加热颗粒,所述加热流体与所述相变材料混合,其中,当供应外部能量时,所述微加热颗粒接收外部能量并产生 将相变材料熔化成流体状态的热量,当没有外部能量供给时,相变材料变硬。