公开(公告)号：US11662309B2

公开(公告)日：2023-05-30

申请号：US17396556

申请日：2021-08-06

Applicant: Opsolution GMBH

Inventor： Bjoern Magnussen ,  Claudius Stern ,  Wolfgang Koecher

IPC: G01N21/49 ,  A61B5/1455 ,  G01N21/47 ,  A61B5/145 ,  G01N21/17

CPC classification number: G01N21/49 ,  A61B5/1455 ,  A61B5/14546 ,  G01N21/474 ,  G01N21/4795 ,  A61B5/14532 ,  A61B2560/0223 ,  A61B2562/046 ,  G01N2021/1782 ,  G01N2021/4752 ,  G01N2201/066 ,  G01N2201/0621 ,  G01N2201/0626 ,  G01N2201/0633 ,  G01N2201/06153 ,  G01N2201/1211 ,  G01N2201/1214

Abstract: A device for optical detection of analytes in a sample includes at least two optoelectronic components. The optoelectronic components include at least one optical detector configured to receive a photon and at least one optical emitter configured to emit a photon. The at least one optical emitter includes at least three optical emitters disposed in a flat, non-linear arrangement, and the at least one optical detector includes at least three optical detectors disposed in a flat, non-linear arrangement. The at least three optical emitters and the at least three optical detectors include at least three different wavelength characteristics.

公开(公告)号：US20180328841A1

公开(公告)日：2018-11-15

申请号：US15578722

申请日：2016-06-03

Applicant: PALO ALTO HEALTH SCIENCES, INC.

Inventor： Paul K. GRAHAM ,  Alexander J. MOSKOS ,  Jackson M. PLEIS ,  Simon W.H. THOMAS

IPC: G01N21/27 ,  A61B5/083 ,  A61B5/097 ,  A61B5/00 ,  A61B5/08 ,  G01N21/78 ,  G01N33/00 ,  G01N33/497

CPC classification number: G01N21/274 ,  A61B5/0816 ,  A61B5/0836 ,  A61B5/097 ,  A61B5/486 ,  A61B5/7405 ,  A61B5/742 ,  A61B2010/0087 ,  A61B2560/0228 ,  A61B2560/0233 ,  A61B2562/029 ,  A61M16/021 ,  A61M16/0672 ,  A61M16/085 ,  A61M16/1045 ,  A61M16/161 ,  A61M2205/3306 ,  A61M2205/584 ,  A61M2230/42 ,  A61M2230/432 ,  G01N21/783 ,  G01N33/004 ,  G01N33/497 ,  G01N2201/1211 ,  G01N2201/1214

Abstract: Quantitative colorimetric carbon dioxide measurement and measurement systems and methods are disclosed. The methods can include methods for calibrating a chemical colorimetric indicator used in the quantitative colorimetric carbon dioxide measurement system. Apparatuses are disclosed including a cartridge comprising a chemical colorimetric indicator that is configured to removably engage with a quantitative colorimetric measurement system. Cartridges containing a sealed container comprising a reference gas with a known concentration of carbon dioxide are also disclosed. Systems and methods for humidifying the chemical colorimetric indicator are also provided. Methods for using the systems are also disclosed including providing a breathing therapy to a patient or user.

公开(公告)号：US5246858A

公开(公告)日：1993-09-21

申请号：US661810

申请日：1991-02-27

Applicant: Steven R. Arbuckle ,  William R. Boyd ,  Michael E. Grant ,  Mark A. Gregory ,  Russell T. Gray ,  Friedrich Jost ,  Daniel L. Kennedy ,  Dino Perin ,  Richard Riedel ,  David E. Storvick ,  John W. Stoughton

Inventor： Steven R. Arbuckle ,  William R. Boyd ,  Michael E. Grant ,  Mark A. Gregory ,  Russell T. Gray ,  Friedrich Jost ,  Daniel L. Kennedy ,  Dino Perin ,  Richard Riedel ,  David E. Storvick ,  John W. Stoughton

IPC: G01N21/47 ,  G01N21/77 ,  G01N21/86 ,  G01N33/52

CPC classification number: G01N21/8483 ,  G01N2021/478 ,  G01N2201/1214 ,  G01N2201/122 ,  G01N2201/12723 ,  Y10T436/10

Abstract: A method and apparatus (10) for determining the remission of a chemistry (106) which reacts with a medically significant component of a body fluid. The remission of the chemistry (106) changes as it reacts. The method and apparatus (10) include irradiating the chemistry (106) with a radiation source (182), detecting remissions of radiation from the chemistry (106) with a radiation detector (300), providing a radiation pathway (164) between the source (182) and the chemistry (106), providing a remission pathway (164) between the chemistry (106) and the detector (300), and detecting the rate of change of remission of the chemistry (106) with respect to time. The irradiating, detecting and rate detecting steps and apparatus comprise initially irradiating the chemistry (106) at a first time rate and detecting remissions therefrom, comparing remission data from remission readings spaced apart by a first number of intervening remission readings, and determining when the difference between compared readings exceeds a first predetermined limit. The time rate of irradiation of the chemistry is changed once the difference between compared readings exceeds the first limit. Remission data from remission readings spaced apart by a second number of intervening remission readings are then compared. The method and apparatus next determine when the difference between compared readings no longer exceeds a second predetermined limit. The last remission reading is then converted to the concentration of the medically significant component of the body fluid.

Abstract translation: 一种用于确定化学物质（106）的缓解的方法和装置（10），其与体液的医学上重要的组分反应。 化学物质（106）的缓解随着反应而发生变化。 该方法和装置（10）包括用辐射源（182）照射化学物质（106），用辐射检测器（300）检测来自化学物质（106）的辐射的放射，提供源之间的辐射通路（164） （106）和化学物质（106），在化学物质（106）和检测器（300）之间提供缓释途径（164），以及检测化学物质（106）相对于时间的缓解变化率。 照射，检测和速率检测步骤和装置包括首先以第一时间速率辐射化学物质（106）并检测其中的缓解，将缓释数据与间隔开的缓冲读数与第一数量的介入缓解读数进行比较，以及确定何时差异 比较读数超过第一预定极限。 一旦比较读数之间的差超过第一限制，化学物质的照射时间变化就会改变。 然后比较缓冲读数与间隔第二数量的介入缓解读数的缓解数据。 该方法和装置接下来确定比较读数之间的差异何时不再超过第二预定极限。 然后将最后的缓解读数转化为体液的医学重要组分的浓度。

公开(公告)号：US4764018A

公开(公告)日：1988-08-16

申请号：US50478

申请日：1987-05-18

Applicant: Hiroki Inoue

Inventor： Hiroki Inoue

IPC: G01N21/31 ,  G01N21/35 ,  G01N21/85 ,  G01J3/51

CPC classification number: G01N21/314 ,  G01N2021/3174 ,  G01N2021/8592 ,  G01N21/3554 ,  G01N2201/0636 ,  G01N2201/1211 ,  G01N2201/1214

Abstract: An apparatus for measuring the water content of an object to be measured comprises in combination a pair of optical filters for obtaining from the same source light a reference light having a wavelength not easily absorbed therein and a measuring light having a wavelength easily absorbable therein, an optical system for irradiating the object with the reference and measuring lights, an photoelectric converter for converting the reference and measuring lights to electrical signals, a temperature detector for detecting the temperature of the optical filters, a humidity detector for detecting the humidity of optical paths for the reference and measuring lights, extending from the optical system to the object, and a water content-measuring circuit for finding the quantity of water contained in the object on the basis of output signals produced from the photoelectric converter, temperature detector and humidity detector.

Abstract translation: 用于测量被测量物体的含水量的装置包括一对光学滤光器，用于从相同的源光获得具有不容易吸收的波长的参考光和具有易于吸收的波长的测量光， 用于用参考和测量光照射物体的光学系统，用于将参考和测量光转换为电信号的光电转换器，用于检测光学滤波器的温度的温度检测器，用于检测光路的湿度的湿度检测器，用于 基于从光学系统延伸到对象的参考和测量光，以及用于基于由光电转换器，温度检测器和湿度检测器产生的输出信号来找到物体中所含的水量的含水量测量电路。

公开(公告)号：US11965823B2

公开(公告)日：2024-04-23

申请号：US17629532

申请日：2020-05-29

Applicant: Foss Analytical A/S

Inventor： Per Waaben Hansen ,  Jeppe Sandvik Clausen

IPC: G01N21/27 ,  G01N21/3577 ,  G01N21/35 ,  G01N33/04

CPC classification number: G01N21/274 ,  G01N21/3577 ,  G01N2021/3595 ,  G01N33/04 ,  G01N2201/1214 ,  G01N2201/129

Abstract: A method of correcting for an amplitude change in a spectrometric instrument output includes: exposing a sample in a sample holder to electromagnetic radiation at a plurality of wavenumbers; detecting electromagnetic absorption intensities in the sample at the plurality of wavenumbers; providing to a computer device the detected electromagnetic absorption intensities indexed against wavenumber as spectral data; applying in the computer device a mathematical transform (Icorr) to the spectral data to correct for an amplitude change in the spectrometric instrument's output and calculated by determining a difference (Δ(SBZ)/) between first derivatives of a logarithmic transformation of spectral data (SBZ) from the zero material sample at two different wavenumber ranges (log10(SBZ(x1))/ and log10(SBZ(x2))/); and calculating the mathematical transform (Icorr) as a function inversely dependent on the determined difference (Δ(SBZ)/).

公开(公告)号：US20160313241A1

公开(公告)日：2016-10-27

申请号：US15102769

申请日：2014-12-02

Applicant: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.

Inventor： Kazuhiro OCHI ,  Tatsuya TAKAHASHI

IPC: G01N21/359 ,  G01N33/02

CPC classification number: G01N21/359 ,  G01N33/02 ,  G01N2201/068 ,  G01N2201/121 ,  G01N2201/1211 ,  G01N2201/1214

Abstract: This calorie measurement device is provided with the following: a light-emission unit that exposes a food article to light that contains near-infrared wavelengths; a light-reception unit that receives transmitted light that had passed through the food article and/or reflected light that was reflected by the food article; a correction unit that computes a base absorbance for the food article on the basis of the transmitted and/or reflected light and corrects the light intensity measured by the light-reception unit and/or the computed base absorbance on the basis of affecting factors, said affecting factors being those that affect the absorption and reflection of light by the food article but are essentially unaffected by the light-absorption and light-reflection properties of the components of the food article; and an analysis unit that computes an analysis value indicating the caloric content of the food article on the basis of the corrected light intensity measured by the light-reception unit and/or the corrected base absorbance.

Abstract translation: 这种卡路里测量装置具有以下装置：将食品暴露于含有近红外波长的光的发光单元; 光接收单元，其接收通过食品的透射光和/或被食品反射的反射光; 校正单元，其基于透射和/或反射光计算食品的基本吸光度，并且基于影响因素校正由光接收单元测量的光强度和/或计算的基底吸光度，所述校正单元 影响因素是影响食品对光的吸收和反射的因素，但基本上不受食品的组分的光吸收和光反射性质的影响; 以及分析单元，其基于由光接收单元测量的校正光强度和/或校正的基本吸光度计算指示食品的热量含量的分析值。

公开(公告)号：US20160077073A1

公开(公告)日：2016-03-17

申请号：US14784629

申请日：2014-04-15

Applicant: DRÄGER SAFETY AG & CO. KGAA

Inventor： Hans-Ullrich HANSMANN ,  Philipp ROSTALSKI

IPC: G01N33/00

CPC classification number: G01N33/0036 ,  G01N21/783 ,  G01N21/81 ,  G01N31/222 ,  G01N31/223 ,  G01N33/0013 ,  G01N33/18 ,  G01N2201/1214 ,  Y02A50/25 ,  Y10T436/25875

Abstract: A reaction carrier (14), a measuring device (12) and a measuring method measure a concentration of gaseous/aerosol components of a gas mixture. The reaction carrier (14) has a flow channel (42) defining a reaction chamber (46) with an optically detectable reaction material (48) reacts with at least one component of the gas mixture or with a reaction product of the component. A humidity measuring element (84), of the reaction carrier (14), detects a humidity of the gas mixture flowing through the flow channel (42). The measuring device (12) has a humidity detection unit (85) that reads the humidity measuring element (84). A humidity determining unit (94) determines a humidity based on the detected humidity. The measuring method determines a humidity of the supplied gas mixture in the flow channel (42) and determines a concentration of the component on the basis of the optically detectable reaction and the measured humidity.

Abstract translation: 反应载体（14），测量装置（12）和测量方法测量气体混合物的气体/气溶胶组分的浓度。 反应载体（14）具有限定反应室（46）的流动通道（42），其中光学可检测的反应材料（48）与气体混合物的至少一种组分或与组分的反应产物反应。 反应载体（14）的湿度测量元件（84）检测流过流道（42）的气体混合物的湿度。 测量装置（12）具有读取湿度测量元件（84）的湿度检测单元（85）。 湿度确定单元（94）基于检测到的湿度确定湿度。 测量方法确定在流动通道（42）中供应的气体混合物的湿度，并且基于光学可检测的反应和测量的湿度来确定组分的浓度。

公开(公告)号：US08879053B2

公开(公告)日：2014-11-04

申请号：US13456259

申请日：2012-04-26

Applicant: Robert Freese ,  Christopher Michael Jones ,  David Perkins ,  Michael Simcock ,  William Soltmann

Inventor： Robert Freese ,  Christopher Michael Jones ,  David Perkins ,  Michael Simcock ,  William Soltmann

IPC: G01N21/00 ,  G01K13/00 ,  G06E3/00 ,  G01N21/27 ,  G01N21/17

CPC classification number: G01N21/17 ,  G01K13/00 ,  G01N21/274 ,  G01N2201/1211 ,  G01N2201/1214 ,  G01N2201/1215 ,  G06E3/001

Abstract: The output of optical computing devices containing an integrated computational element can be corrected when an interferent substance or condition is present. The devices may comprise an optional electromagnetic radiation source; a sample detection unit comprising an integrated computational element and a detector configured to receive electromagnetic radiation that has optically interacted with the integrated computational element and produce a sample signal associated therewith; an interferent monitor located proximal to the sample detection unit, the interferent monitor being configured to produce an interferent signal associated with an interferent substance; and a signal processing unit operable to convert the interferent signal into an interferent input form suitable for being computationally combined with the sample signal, the signal processing unit being further operable to computationally combine the sample signal and the interferent input form to determine a characteristic of a sample in real-time or near real-time.

Abstract translation: 当存在干扰物质或条件时，可以校正包含集成计算元件的光学计算装置的输出。 这些装置可以包括可选的电磁辐射源; 样本检测单元，包括集成的计算元件和被配置为接收与所述集成的计算元件光学相互作用并产生与其相关联的采样信号的电磁辐射的检测器; 位于样本检测单元附近的干扰物监测器，所述干扰物监测器被配置为产生与干扰物质相关的干扰信号; 信号处理单元，可操作以将干扰信号转换成适于与采样信号进行计算组合的干扰输入形式，所述信号处理单元进一步可操作以计算地组合采样信号和干扰输入形式，以确定 实时或近实时采样。

公开(公告)号：US20130287061A1

公开(公告)日：2013-10-31

申请号：US13456259

申请日：2012-04-26

Applicant: Robert Freese ,  Christopher Michael Jones ,  David Perkins ,  Michael Simcock ,  Bill Soltmann

Inventor： Robert Freese ,  Christopher Michael Jones ,  David Perkins ,  Michael Simcock ,  Bill Soltmann

IPC: G01N21/17 ,  G01K13/00

CPC classification number: G01N21/17 ,  G01K13/00 ,  G01N21/274 ,  G01N2201/1211 ,  G01N2201/1214 ,  G01N2201/1215 ,  G06E3/001

Abstract: The output of optical computing devices containing an integrated computational element can be corrected when an interferent substance or condition is present. The devices may comprise an optional electromagnetic radiation source; a sample detection unit comprising an integrated computational element and a detector configured to receive electromagnetic radiation that has optically interacted with the integrated computational element and produce a sample signal associated therewith; an interferent monitor located proximal to the sample detection unit, the interferent monitor being configured to produce an interferent signal associated with an interferent substance; and a signal processing unit operable to convert the interferent signal into an interferent input form suitable for being computationally combined with the sample signal, the signal processing unit being further operable to computationally combine the sample signal and the interferent input form to determine a characteristic of a sample in real-time or near real-time.

Abstract translation: 当存在干扰物质或条件时，可以校正包含集成计算元件的光学计算装置的输出。 这些装置可以包括可选的电磁辐射源; 样本检测单元，包括集成的计算元件和被配置为接收与所述集成的计算元件光学相互作用并产生与其相关联的采样信号的电磁辐射的检测器; 位于样本检测单元附近的干扰物监测器，所述干扰物监测器被配置为产生与干扰物质相关的干扰信号; 信号处理单元，可操作以将干扰信号转换成适合于与采样信号进行计算组合的干扰输入形式，所述信号处理单元还可操作以计算地组合采样信号和干扰输入形式，以确定 实时或近实时采样。

公开(公告)号：US20040042079A1

公开(公告)日：2004-03-04

申请号：US10233940

申请日：2002-09-03

Inventor： John Phillip Ertel ,  William Richard Trutna JR.

IPC: G02B005/18 ,  G02B027/42 ,  G02B027/44

CPC classification number: G02B7/003 ,  G01N21/45 ,  G01N2021/4106 ,  G01N2201/1211 ,  G01N2201/1214 ,  G01N2201/1218 ,  G01S7/497 ,  Y10S359/90

Abstract: Optical systems are provided. One such optical system includes an optical source that propagates a source beam of light. A diffracting component is optically coupled to the optical source and is operative to receive the source beam and produce a diffracted beam. A target is located to receive the diffracted beam. Additionally, a compensating system repositions at least one of the optical source, the diffracting component, and the target in response to a detected change in refractive index of a medium through which the diffracted beam propagates so that the diffracted beam continues to be received by the target. Methods and other systems also are provided.

Abstract translation: 提供光学系统。 一种这样的光学系统包括传播源光束的光源。 衍射组件光耦合到光源并且可操作地接收源光束并产生衍射光束。 目标位于接收衍射光束。 另外，补偿系统响应于所检测到的衍射光束传播的介质的折射率变化，重新定位光源，衍射部件和靶中的至少一个，使得衍射光束继续被 目标。 还提供了方法和其它系统。