公开(公告)号：US12053164B2

公开(公告)日：2024-08-06

申请号：US17127520

申请日：2020-12-18

申请人： Access Sensor Technologies LLC ,  Colorado State University Research Foundation

发明人： David Leith ,  John Volckens ,  Christian L'Orange ,  Daniel D. Miller-Lionberg

IPC分类号： A61B10/00 ,  G01N1/22 ,  G01N15/02

CPC分类号： A61B10/00 ,  G01N1/2208 ,  G01N1/2211 ,  G01N1/2273 ,  G01N15/0255 ,  A61B2010/0087 ,  G01N2015/0261

摘要： A portable sampler, the sampler including a sampler assembly having a housing that includes a receiver defined therein for interchangeably receiving a number of removable inlet assemblies, the removable inlet assemblies including a respirable inlet assembly and a thoracic inlet assembly. The respirable inlet assembly includes a hybrid cyclone assembly, the hybrid cyclone assembly including an impaction stage and a cyclone in series. The thoracic inlet assembly includes an inlet slot configured to function as a size-selective inlet. Another thoracic inlet assembly includes a housing having a number of openings configured to receive a sample airflow; an inlet insert through which an inlet aperture is defined; a prequalification chamber defined between a lower surface of the housing and an upper surface of the inlet insert; and a protrusion extending downward from the lower surface of the housing into the inlet aperture of the inlet insert to from an inlet slot.

公开(公告)号：US12029547B2

公开(公告)日：2024-07-09

申请号：US17238052

申请日：2021-04-22

申请人： Hyperspectral Corp.

发明人： David M. Palacios ,  Harry Hopper

IPC分类号： A61B5/08 ,  A61B5/00 ,  A61B5/097 ,  A61B10/00 ,  G01J3/18 ,  G01J3/45 ,  G01N1/42 ,  G01N21/25 ,  G01N21/3504 ,  G01N21/359 ,  G01N33/497

CPC分类号： A61B5/082 ,  A61B5/7282 ,  A61B10/00 ,  G01J3/18 ,  G01J3/45 ,  G01N1/42 ,  G01N21/255 ,  G01N21/3504 ,  G01N21/359 ,  G01N33/497 ,  A61B5/097 ,  A61B2010/0087 ,  G01N2033/4975 ,  G01N2201/063

摘要： A method comprising at least one light source configured to generate a light of at least one wavelength and project the light over an optical path, a sample device, the device containing a sample obtained from exhalation of a person, a vortex mask configured to receive the light after the light passes through at least a portion of the sample device, the vortex mask including a series of concentric circles etched in a substrate, the vortex mask configured to provide destructive interference of coherent light received from the at least one light source, a detector configured to detect and measure wavelength intensities from the light in the optical path, the wavelength intensities being impacted by the light passing through the sample, the detector receiving the light that remained after passing through the vortex mask, and a processor configured to provide measurement results based on the wavelength intensities.

公开(公告)号：US20240215961A1

公开(公告)日：2024-07-04

申请号：US18556204

申请日：2022-05-05

申请人： Avelo AG

发明人： Tobias Broger

IPC分类号： A61B10/00 ,  A61B5/08 ,  A61B5/097

CPC分类号： A61B10/0045 ,  A61B5/082 ,  A61B5/097 ,  A61B2010/0087 ,  A61B2560/0431

摘要： A device, system and method for collecting and eluting aerosol particles contained in a breath sample of a human or animal for the purpose of sampling non-volatile respiratory pathogens present in the breath sample. In at least some embodiments, the present invention provides such a device, system and method to collect, preserve, concentrate and release pathogen-specific biomarkers from breath aerosols for the subsequent analysis with immunoassays and molecular assays for the clinical diagnosis of respiratory tract infections in humans. The sampling device comprises an aqueous solution dissolvable polymer membrane installed in a housing of the sampling device in the flow path of the breath aerosol that sorbs the aerosol particles. The sampling device further comprises an engagement means for releasably engaging an elution device to the housing for introducing an aqueous solution into the housing and for dissolving the polymer membrane upon contact with the aqueous solution.

公开(公告)号：US12019056B2

公开(公告)日：2024-06-25

申请号：US17499848

申请日：2021-10-12

申请人： Zeteo Tech, Inc.

发明人： Dapeng Chen ,  Wayne A. Bryden ,  Michael McLoughlin

IPC分类号： G01N33/497 ,  A61B5/08 ,  A61B5/091 ,  A61B5/097 ,  A61B10/00 ,  G01N30/72 ,  A61B5/087 ,  G01N30/02

CPC分类号： G01N30/7206 ,  A61B5/082 ,  A61B5/091 ,  A61B5/097 ,  A61B10/0045 ,  G01N33/497 ,  A61B5/087 ,  A61B2010/0087 ,  A61B2562/029 ,  G01N2030/025 ,  G01N2800/12

摘要： Disclosed are methods and devices for analyzing aerosol particles in exhaled breath using diagnostic tools that enable rapid, low cost and autonomous point of care assays for several diseases including respiratory tract diseases. Disclosed are methods and devices for capturing exhaled breath aerosols in a packed bed column and analyzing exhaled captured breath aerosols for tuberculosis diagnosis.

公开(公告)号：US20240081675A1

公开(公告)日：2024-03-14

申请号：US18251075

申请日：2021-11-01

申请人： THE CHILDREN'S HOSPITAL OF PHILADELPHIA

发明人： Audrey Ragan ODOM JOHN ,  Amalia Zoraida BERNA PEREZ ,  Elikplim AKAHO

IPC分类号： A61B5/08 ,  G01N33/497

CPC分类号： A61B5/082 ,  G01N33/497 ,  A61B2560/0431 ,  A61B2010/0087

摘要： Compositions and methods for the diagnosis and treatment of Covid 19 are disclosed.

公开(公告)号：US20230389866A1

公开(公告)日：2023-12-07

申请号：US18201059

申请日：2023-05-23

申请人： BI Incorporated

发明人： Ric Miller

IPC分类号： A61B5/00 ,  G10L15/06 ,  G10L25/51 ,  G10L15/22

CPC分类号： A61B5/4845 ,  A61B5/4803 ,  A61B5/7275 ,  A61B5/7267 ,  G10L15/063 ,  G10L25/51 ,  G10L15/22 ,  A61B2010/0087

摘要： Various embodiments provide systems and methods for identifying impairment using measurement devices and trained models, and/or for indicating interference with impairment testing. Embodiments discussed herein provide systems, methods, and/or devices that enable remote impairment testing that does not require a human monitor to be present or physically near the individual being monitored. Such an ability is an improvement.

公开(公告)号：US20230366041A1

公开(公告)日：2023-11-16

申请号：US18026160

申请日：2021-09-16

申请人： NORTHWESTERN UNIVERSITY

发明人： Christina Maria Zelano ,  Gregory Lane

IPC分类号： C12Q1/70 ,  C12Q1/6851 ,  G01N1/42 ,  A61B5/097 ,  A61B10/00

CPC分类号： C12Q1/701 ,  C12Q1/6851 ,  G01N1/42 ,  A61B5/097 ,  A61B10/00 ,  A61B2010/0087

摘要： A method for measuring the presence of SARS-CoV-2 or other respiratory pathogen in a person comprises collecting a sample of condensed exhaled breath from the person and measuring the presence of SARS-CoV-2 or other respiratory pathogen in said sample, thus providing a method for determining whether a person is capable of transmitting SARS-CoV-2 or other respiratory pathogen to other persons.

公开(公告)号：US11779271B2

公开(公告)日：2023-10-10

申请号：US17563454

申请日：2021-12-28

申请人： Invoy Holdings Inc.

发明人： Lubna M. Ahmad ,  Salman A. Ahmad ,  Zachary Smith

IPC分类号： A61B5/00 ,  G08B21/18 ,  A61B5/08 ,  G06F3/0482 ,  G06F3/04842 ,  G06F9/451 ,  H04W4/80 ,  G01N33/64 ,  G01N33/497 ,  H04L43/045 ,  A61B5/083 ,  A61B5/097 ,  A61B10/00

CPC分类号： A61B5/4833 ,  A61B5/0015 ,  A61B5/0022 ,  A61B5/0024 ,  A61B5/082 ,  A61B5/083 ,  A61B5/097 ,  A61B5/486 ,  A61B5/4866 ,  A61B5/6898 ,  A61B5/7264 ,  A61B5/7267 ,  A61B5/742 ,  A61B5/743 ,  A61B5/7405 ,  A61B5/7475 ,  G01N33/497 ,  G01N33/64 ,  G06F3/0482 ,  G06F3/04842 ,  G06F9/453 ,  G08B21/18 ,  G08B21/182 ,  H04L43/045 ,  H04W4/80 ,  A61B2010/0087 ,  A61B2560/045 ,  A61B2560/0431 ,  G01N2033/4975

摘要： A portable system is provided for measuring an analyte, such as acetone, in the breath or other bodily fluid of a user. The system includes a portable measurement device that analyzes fluid samples and generates corresponding measurements. The portable measurement device communicates with an application which runs on a smartphone or other mobile device of the user. The application tracks, and generates graphs of, the measurements, and may include various features for facilitating the analysis of the measurements.

公开(公告)号：US20230277125A1

公开(公告)日：2023-09-07

申请号：US18005622

申请日：2021-07-16

申请人： UNIVERSITÄTS-KINDERSPITAL BEIDER BASEL ,  UNIVERSITÄT ZÜRICH

发明人： Kapil Dev SINGH ,  Amanda GISLER ,  Martin OSSWALD ,  Malcolm KOHLER ,  Johannes VAN DEN ANKER ,  Nicolas VON DER WEID ,  Urs FREY ,  Alexandre DATTA ,  Pablo SINUES

IPC分类号： A61B5/00 ,  A61B5/08 ,  A61B5/097 ,  G01N33/574

CPC分类号： A61B5/4848 ,  A61B5/082 ,  A61B5/7264 ,  A61B5/7275 ,  A61B5/097 ,  G01N33/574 ,  A61B2010/0087

摘要： The present invention relates to an ex vivo method and means for determining the risk estimate of side effects of a drug and/or probability estimate of drug response in a subject, the method comprising collecting the mass spectra of substances present in the exhaled breath and analyzing the mass spectra using a previously trained mathematical model. The instant methods and means are particularly useful in therapeutic drug monitoring, determining the risk estimate of side effects of a drug, determining the probability estimate of drug response in the subject, and determination of subject compliance.

公开(公告)号：US20230210502A1

公开(公告)日：2023-07-06

申请号：US17921720

申请日：2021-04-28

申请人： VITALOGRAPH (IRELAND) LTD.

发明人： Frank Keane ,  Colum Dunne

IPC分类号： A61B10/00 ,  A61B5/097

CPC分类号： A61B10/00 ,  A61B5/097 ,  A61B2010/0087

摘要： An air sampling device (1) for collecting airborne microorganisms comprising an air inlet piece (2), an air outlet piece (3) and a filter chamber (4) for receiving a filter (5) between the air inlet piece (2) and the air outlet piece (3) wherein the sampling device (1) comprises an openable fastener (6) to provide ease of access to the filter chamber (4).