公开(公告)号：US11573171B2

公开(公告)日：2023-02-07

申请号：US16821538

申请日：2020-03-17

Applicant: OLYMPUS CORPORATION

Inventor： Ikutoshi Fukushima ,  Shogo Usui ,  Tsuyoshi Mochizuki ,  Masaru Mizunaka ,  Shintaro Takahashi

IPC: H04N7/18 ,  G01N21/27 ,  G06T7/90 ,  H04N9/04 ,  C12M1/00 ,  C12M1/34 ,  G01N21/25 ,  G02B21/06 ,  G02B21/36 ,  G06T7/00 ,  H04N5/225

Abstract: An observation system includes an observation apparatus including a housing having an arrangement surface for placement of a sample, the sample including a culture medium, and an external illumination unit which is disposed outside the housing and includes at least one light source configured to emit illumination light. At least a part of the arrangement surface is formed of a transparent member having an optically transparent property. The observation apparatus includes an imaging unit which is provided in the housing and includes an image sensor configured to image, via the transparent member, the sample illuminated by the illumination light from the external illumination unit to acquire images of at least three colors.

公开(公告)号：US11226476B2

公开(公告)日：2022-01-18

申请号：US16366682

申请日：2019-03-27

Applicant: OLYMPUS CORPORATION

Inventor： Tsuyoshi Mochizuki ,  Shintaro Takahashi ,  Akira Matsushita ,  Yohei Tanikawa ,  Masaru Mizunaka ,  Shinichi Takimoto

IPC: G02B21/34 ,  G02B21/08 ,  G02B21/26 ,  G02B21/36 ,  G01N21/59 ,  G01N21/01 ,  G02B21/33 ,  G01N21/17 ,  C12M1/34

Abstract: An observation apparatus including: a top plate on which a container in which a specimen is accommodated can be placed, and through which illumination light can pass; a light source that emits the illumination light upward from below the specimen; an objective lens that focuses, below the specimen and the top plate, transmitted light which is the illumination light that has passed through the specimen from thereabove and that has passed through the top plate; and a camera that captures the transmitted light, wherein the light source emits the illumination light toward an area above the specimen from outside the objective lens in a radial direction, and the top plate is provided with a mark that specifies a viewing-field area of the camera.

公开(公告)号：US11137588B2

公开(公告)日：2021-10-05

申请号：US16364946

申请日：2019-03-26

Applicant: OLYMPUS CORPORATION

Inventor： Masaru Mizunaka ,  Shintaro Takahashi ,  Akira Matsushita ,  Yohei Tanikawa ,  Tsuyoshi Mochizuki ,  Shinichi Takimoto

IPC: G02B21/06 ,  G02B21/16 ,  G02B21/02 ,  G02B21/12 ,  G01N21/64 ,  G02B21/36 ,  G02B21/10 ,  G01N21/17 ,  G02B21/24 ,  G02B21/33

Abstract: An observation apparatus including: a light-source that emits illumination light and excitation light upward from below a specimen; and an image-capturing optical system having an objective lens that focuses, below the specimen, transmitted light, which is the illumination light that is emitted from the light-source, that is reflected above the specimen, and that has passed through the specimen, and fluorescence that is generated in the specimen that has been irradiated with the excitation light emitted from the light-source, wherein the light-source is disposed radially outside the objective lens.

公开(公告)号：US20200318058A1

公开(公告)日：2020-10-08

申请号：US16904799

申请日：2020-06-18

Applicant: OLYMPUS CORPORATION

Inventor： Tsuyoshi Mochizuki ,  Koh Mohri ,  Yoshihito Iguchi ,  Shogo Usui ,  Shintaro Takahashi ,  Asuka Nakamura ,  Shoichi Kaneko ,  Ikutoshi Fukushima ,  Masaru Mizunaka

IPC: C12M1/34 ,  G01N21/25 ,  G01N21/31 ,  C12M1/00 ,  C12M1/36 ,  G06T7/90 ,  G06T7/00 ,  H04N5/225

Abstract: An observation system includes an illumination unit including a light source from which emits an illumination light including light of a plurality of colors, and light receiving unit including an optical sensor which acquires a light intensity. The illumination unit emits the illumination light for a culture vessel so that the illumination light travels from a first side to a second side of the culture vessel, the first side and the second side being defined by interposing a culture medium. The light receiving unit receives, on the first side, light emitted from the illumination unit, entering the culture vessel from the first side, reflected at the second side, and transmitted through the culture medium, and acquires a light intensity for each color in the received light for calculation of a pH value of the culture medium.

公开(公告)号：US20200217782A1

公开(公告)日：2020-07-09

申请号：US16821538

申请日：2020-03-17

Applicant: OLYMPUS CORPORATION

Inventor： Ikutoshi Fukushima ,  Shogo Usui ,  Tsuyoshi Mochizuki ,  Masaru Mizunaka ,  Shintaro Takahashi

IPC: G01N21/27 ,  H04N5/225 ,  H04N9/04 ,  G06T7/90 ,  G06T7/00 ,  C12M1/00 ,  C12M1/34 ,  G02B21/36 ,  G02B21/06 ,  G01N21/25

Abstract: An observation system includes an observation apparatus including a housing having an arrangement surface for placement of a sample, the sample including a culture medium, and an external illumination unit which is disposed outside the housing and includes at least one light source configured to emit illumination light. At least a part of the arrangement surface is formed of a transparent member having an optically transparent property. The observation apparatus includes an imaging unit which is provided in the housing and includes an image sensor configured to image, via the transparent member, the sample illuminated by the illumination light from the external illumination unit to acquire images of at least three colors.