公开(公告)号：US20240192139A1

公开(公告)日：2024-06-13

申请号：US18285298

申请日：2022-02-09

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Kengo SUZUKI ,  Kenichiro IKEMURA ,  Kazuya IGUCHI

IPC: G01N21/64 ,  G01N21/95

CPC classification number: G01N21/6489 ,  G01N21/6456 ,  G01N21/9505

Abstract: A measurement device includes: an excitation optical system; an illumination optical system, and an image capturing unit. The illumination optical system includes a light transmission member having a central region that has a first color and a peripheral region that has a second color and surrounds the central region, and the excitation optical system and the illumination optical system are optically connected to each other such that in a field of view of the image capturing unit, an irradiation spot of the excitation light on the subject to be measured is included in a central spot region of the illumination light that has passed through the central region and is surrounded by a peripheral spot region of the illumination light that has passed through the peripheral region.

公开(公告)号：US20240183795A1

公开(公告)日：2024-06-06

申请号：US18285281

申请日：2022-02-18

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Kenichiro IKEMURA ,  Kengo SUZUKI ,  Kazuya IGUCHI ,  Akihiro NAKAMURA

IPC: G01N21/95

CPC classification number: G01N21/9505 ,  G01N2201/065

Abstract: A measuring device includes: an integrating sphere; an excitation optical system; a light detector; and a first detection optical system. The optical axis of the excitation light incident on the subject to be measured in the integrating sphere in the excitation optical system and the optical axis of the light to be measured that is emitted from the integrating sphere in the first detection optical system obliquely intersect with each other, the first detection optical system has an opening portion that limits a detection range of the light to be measured in the light detector, and an irradiation spot of the excitation light on the subject to be measured and the opening portion are in an optically conjugate relationship.

公开(公告)号：US20220373480A1

公开(公告)日：2022-11-24

申请号：US17772282

申请日：2020-10-27

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tomonori NAKAMURA ,  Kenichiro IKEMURA

IPC: G01N21/956 ,  G01N21/64 ,  G01B11/27

Abstract: An inspection apparatus includes a light source unit, cameras, a keyboard, and a controller that determines a wavelength of the excitation light, based on the information on the emission color received by the keyboard, and that controls the light source unit so that the light source unit generates excitation light with the determined wavelength. The controller determines a wavelength longer than an absorption edge wavelength of the substrate of the sample and shorter than a peak wavelength of an emission spectrum of the light-emitting element, the peak wavelength being specified from the information on the emission color, to be the wavelength of the excitation light.

公开(公告)号：US20220198644A1

公开(公告)日：2022-06-23

申请号：US17441711

申请日：2020-01-29

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tomonori NAKAMURA ,  Kenichiro IKEMURA ,  Akihiro OTAKA

IPC: G06T7/00 ,  G06T7/90 ,  H04N5/235 ,  G06T7/66 ,  G01N21/64

Abstract: An inspection apparatus is an inspection apparatus includes an excitation light source that generates excitation light to irradiate the object, a dichroic mirror that separates fluorescence from the sample by transmitting or reflecting the fluorescence according to a wavelength, a camera that images fluorescence reflected by the dichroic mirror, a camera that images fluorescence transmitted through the dichroic mirror, and a control apparatus that derives color irregularity information of a light-emitting element based on a first fluorescence image acquired by the camera and a second fluorescence image acquired by the camera, and an edge shift width corresponding to a width of a wavelength band in which transmittance and reflectance change according to a change in wavelength in the dichroic mirror is wider than a full width at half maximum of a normal fluorescence spectrum of the light-emitting element.

公开(公告)号：US20170212047A1

公开(公告)日：2017-07-27

申请号：US15312771

申请日：2015-04-07

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Shigeru EURA ,  Kengo SUZUKI ,  Kenichiro IKEMURA ,  Kazuya IGUCHI

IPC: G01N21/64 ,  G01J3/443

CPC classification number: G01N21/64 ,  G01J3/0254 ,  G01J3/443 ,  G01N2201/12753

Abstract: An optical measurement device inputs excitation light to an integrating sphere in which a sample is disposed, irradiates the sample with the excitation light having a predetermined beam cross-section, detects measurement light output from the integrating sphere by a photodetector, and acquires intensity data of the sample. The optical measurement device includes a storage unit in which correction data is stored and an optical characteristic calculation unit for calculating optical characteristics of the sample based on the intensity data of the sample and the correction data. The correction data is calculated based on first corrective intensity data and second corrective intensity data. The predetermined beam cross-section is covered with the first light absorbing member and covers the second light absorbing member.

公开(公告)号：US20240344985A1

公开(公告)日：2024-10-17

申请号：US18293518

申请日：2022-07-25

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Takafumi HIGUCHI ,  Kenichiro IKEMURA

IPC: G01N21/64 ,  G06T7/00

CPC classification number: G01N21/6456 ,  G01N21/6428 ,  G06T7/0002 ,  G01N2021/6439 ,  G06T2207/10064

Abstract: A dye image acquisition system includes an image acquisition device that irradiates a sample with each of excitation light beams having C wavelength distributions and acquires the C fluorescence images each including N pixels; and an image processing device that clusters the N pixels into L (L is an integer of 2 or more and N−1 or less) pixel groups based on fluorescence intensities of respective pixels of the C fluorescence images, generates L cluster matrices in which the C fluorescence images are arranged, calculates statistical values of the fluorescence intensities of the pixel groups configuring the C fluorescence images, and performs unmixing on the C fluorescence images by using the statistical values of the C fluorescence images, and generates K (K is an integer of 2 or more and C or less) dye images indicating a distribution for each K dyes.

公开(公告)号：US20240175825A1

公开(公告)日：2024-05-30

申请号：US18285292

申请日：2022-02-18

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Kenichiro IKEMURA ,  Kengo SUZUKI ,  Kazuya IGUCHI ,  Akihiro NAKAMURA

IPC: G01N21/95 ,  G01N21/64

CPC classification number: G01N21/9501 ,  G01N21/6489

Abstract: A measuring device includes: an excitation light source; an integrating sphere; an excitation optical system; a light detector; and a first detection optical system, wherein the first detection optical system has an opening portion, the excitation optical system and the first detection optical system have a separation optical element, a first converging element, and a second converging element, wherein the optical axis of the excitation light incident on the subject to be measured and the optical axis of the light to be measured emitted from the integrating sphere obliquely intersect with each other by means of the separation optical element and the first converging element, and wherein an irradiation spot and the opening portion are in an optically conjugate relationship by means of the first converging element and the second converging element.

公开(公告)号：US20200096389A1

公开(公告)日：2020-03-26

申请号：US16612469

申请日：2018-04-02

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Kenichiro IKEMURA ,  Kazuya IGUCHI ,  Shigeru EURA ,  Akihiro NAKAMURA

IPC: G01J3/443 ,  G01J3/02

Abstract: A spectrometry device includes: an integrating sphere which includes an inner wall surface and an attachment hole; an adapter which includes a guide hole guiding the measurement target light and is disposed in the integrating sphere; a plate which includes a first surface covering the guide hole from the outside of the integrating sphere and allowing a sample to be mounted thereon and a second surface and through which the measurement target light is transmitted; a holder which includes a concave portion mounting the plate thereon and is attached to the attachment hole; and a spectral detector configured to detect the measurement target light. The concave portion includes a bottom surface facing the second surface and a side surface surrounding the periphery of the plate. The bottom surface and the side surface are coated with a reflective material reflecting the measurement target light.

公开(公告)号：US20150377770A1

公开(公告)日：2015-12-31

申请号：US14764805

申请日：2013-09-17

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Shigeru EURA ,  Kengo SUZUKI ,  Kenichiro IKEMURA ,  Kazuya IGUCHI

IPC: G01N21/31 ,  G01J3/42

CPC classification number: G01N21/31 ,  G01J3/0254 ,  G01J3/0291 ,  G01J3/42 ,  G01J3/4406 ,  G01N21/645 ,  G01N21/6489 ,  G01N2021/6469 ,  G01N2021/6482 ,  G01N2021/6491 ,  G01N2201/062 ,  G01N2201/065 ,  G01N2201/12

Abstract: A spectral measurement apparatus includes a light source for generating a excitation light; an integrator having an input opening portion and an output opening portion; a housing portion arranged in the integrator and for housing a sample; an incidence optical system for making the excitation light incident to the sample; a photodetector for detecting a light to be measured output from the output opening portion; and an analysis means for calculating a light absorptance of the sample, based on a detection value detected by the photodetector, and an irradiation area with the excitation light at a position of incidence to the sample is set larger than an irradiated area of the sample, and the analysis means performs an area ratio correction regarding the irradiation area with the excitation light and the irradiated area of the sample, with respect to the light absorptance calculated.

Abstract translation: 光谱测量装置包括用于产生激发光的光源; 积分器，具有输入开口部分和输出开口部分; 布置在所述积分器中并用于容纳样品的壳体部分; 用于使激发光入射到样品的入射光学系统; 用于检测从所述输出开口部分输出的待测光的光电检测器; 以及分析装置，用于基于由所述光电检测器检测的检测值来计算样品的光吸收率，并且将入射到所述样品的位置处的激发光的照射面积设定为大于所述样品的照射面积， 并且分析装置相对于计算的光吸收率执行关于具有激发光的照射区域和样品的照射面积的面积比率校正。

公开(公告)号：US20150346096A1

公开(公告)日：2015-12-03

申请号：US14764703

申请日：2013-09-17

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Kengo SUZUKI ,  Kazuya IGUCHI ,  Shigeru EURA ,  Kenichiro IKEMURA

IPC: G01N21/64 ,  G01N21/01

CPC classification number: G01N21/645 ,  G01J3/021 ,  G01J3/0254 ,  G01J3/0291 ,  G01J3/4406 ,  G01N21/01 ,  G01N21/6489 ,  G01N2021/6469 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/065

Abstract: A spectral measurement apparatus for irradiating a sample as a measurement object with excitation light and detecting light to be measured includes a light source generating the excitation light; an integrator having an input opening portion through which the excitation light is input, and an output opening portion from which the light to be measured is output; a housing portion arranged in the integrator and housing the sample; an incidence optical system making the excitation light incident to the sample; a photodetector detecting the light to be measured output from the output opening portion; and an analysis device calculating a quantum yield of the sample, based on a detection value detected by the photodetector, and the excitation light is applied to the sample so as to include the sample.

Abstract translation: 用于用激发光照射样品作为测量对象并检测待测光的光谱测量装置包括产生激发光的光源; 积分器具有输入激励光的输入开口部分和输出被测光的输出开口部分; 布置在所述积分器中并容纳所述样品的壳体部分; 使入射到样品的激发光的入射光学系统; 检测从所述输出开口部输出的被测光的光检测器; 以及基于由光电检测器检测的检测值来计算样品的量子产率的分析装置，并且将激发光施加到样品以包括样品。