-
公开(公告)号：US20170202467A1
公开(公告)日：2017-07-20
申请号：US15411936
申请日：2017-01-20
CPC分类号： A61B5/04001 , A61B5/0031 , A61B5/6877 , A61B5/7225 , A61B2560/0219 , A61B2562/12 , A61B2562/162 , A61N1/0556 , A61N1/36053 , A61N1/3606 , A61N1/37205 , A61N1/37229 , A61N1/37518 , A61N1/3756 , A61N1/3787
摘要： Methods and apparatuses (e.g., devices and systems) for vagus nerve stimulation, including (but not limited to) sub-diaphragmatic vagus nerve stimulation. In particular, the methods and apparatuses described herein may be used to stimulate the posterior sub-diaphragmatic vagus nerve to treat inflammation and/or inflammatory disorders. The implantable microstimulators described herein may be inductively charged and/or communicated with using the external charger. The implant may include a receiving antenna wrapped around the battery and/or the housing of the microstimulator/microregulator and/or may include a high magnetic permeability material in order to serve as a magnetic core for the antenna coil. Wearable inductive chargers/communication devices for inductively communicating with (including charging) an implanted microstimulator are described herein, which may include magnetically conductive material to enhance communication with an implant, including sub-diaphragmatic implants. Also described herein are inductive chargers/communication devices, including belts, and pads (e.g., mattresses) able to recharge an implanted neurostimulation device.
-
公开(公告)号：US20170197076A1
公开(公告)日：2017-07-13
申请号：US15406619
申请日：2017-01-13
CPC分类号： A61N1/0556 , A61B5/04001 , A61B5/4047 , A61B5/4824 , A61B5/4839 , A61B5/4848 , A61B5/6877 , A61B2505/09 , A61B2562/168 , A61M5/14236 , A61M2005/1726 , A61M2205/3584 , A61M2230/08 , A61N1/3606 , A61N1/36071 , A61N1/37205
摘要： A nerve cuff for establishing a nerve block on a nerve can have a cuff body with a channel for receiving a nerve, a reservoir for holding a drug, and an elongate opening slit extending the length of the cuff body that can be opened to provide access to the channel and can be closed to enclose the cuff body around the nerve. The nerve cuff can also include an electrode for detecting and measuring electrical signals generated by the nerve. A controller can be used to control delivery of the drug based on the electrical signals generated by the nerve.
-
3.发明申请公开(公告)号：US20120290035A1
公开(公告)日：2012-11-15
申请号：US13467928
申请日：2012-05-09
申请人： Jacob A. Levine , Michael A. Faltys
发明人： Jacob A. Levine , Michael A. Faltys
IPC分类号： A61N1/36
CPC分类号： A61N1/36053 , A61N1/3606 , F04C2270/0421
摘要： Described herein are methods and systems for applying extremely low duty-cycle stimulation sufficient to treat chronic inflammation. In particular, described herein are single supra-threshold pulses of electrical stimulation sufficient to result in a long-lasting (e.g., >4 hours, greater than 12 hours, greater than 24 hours, greater than 48 hours) inhibition of pro-inflammatory cytokines and/or effects of chronic inflammation. These methods and devices are particularly of interest in treatment of inflammatory bowel disease (IBD).
摘要翻译： 本文描述的是应用极低的占空比刺激足以治疗慢性炎症的方法和系统。 特别地，本文描述的是电刺激的单一超阈值脉冲，其足以导致促炎细胞因子的持久（例如> 4小时，大于12小时，大于24小时，大于48小时）的抑制 和/或慢性炎症的作用。 这些方法和装置在治疗炎症性肠病（IBD）中特别有意义。
-
公开(公告)号：US07899543B2
公开(公告)日：2011-03-01
申请号：US11839427
申请日：2007-08-15
申请人： Lee F. Hartley , Michael A. Faltys
发明人： Lee F. Hartley , Michael A. Faltys
IPC分类号： A61N1/36
CPC分类号： A61N1/36036 , A61N1/0541 , A61N1/37235
摘要： A network interface module that forms part of a bilateral cochlear implant system which allows two standalone BTE units to be synchronized both temporally and tonotopically in order to maximize a patients listening experience. The bilateral cochlear network includes a communications interposer adapted to be inserted between the BTE battery and the BTE housing or modified BTE devices.
摘要翻译： 形成双边耳蜗植入系统的一部分的网络接口模块，其允许两个独立的BTE单元在时间上和tonotopically同步，以最大限度地提高患者的听力体验。 双侧耳蜗网络包括适于插入在BTE电池和BTE壳体或修改的BTE装置之间的通信插入器。
-
公开(公告)号：US20090264962A1
公开(公告)日：2009-10-22
申请号：US12495593
申请日：2009-06-30
IPC分类号： H04R25/00
CPC分类号： H04R25/70 , A61N1/36036
摘要： Methods and systems for modifying the parameters of at least one hearing device for a patient with residual hearing provide needed orchestration of acoustic and electric stimulation of patients wearing such devices.
-
公开(公告)号：US20090222064A1
公开(公告)日：2009-09-03
申请号：US12437861
申请日：2009-05-08
CPC分类号： A61N1/36036
摘要： Disclosed is a cochlear stimulation system having patient parameters that reside in memory of an internal portion of the system. Different external systems define how the cochlear stimulation system processes a received acoustic signal and uses patient information uploaded from an implant to parameterize system processing. The external system uses external and internal processing capability to convert acoustic signals to electrical stimulus most appropriate for the patient. Because the patient parameters reside internally, the external portion of the system can be replaced to provide an external replacement processor and potentially offer the patient an new type of program without having to re-program the cochlear stimulation system.
摘要翻译： 公开了一种具有驻留在系统的内部部分的存储器中的患者参数的人工耳蜗刺激系统。 不同的外部系统定义了人工耳蜗刺激系统如何处理接收到的声信号并使用从植入物上传的患者信息参数化系统处理。 外部系统使用外部和内部处理能力将声学信号转换为最适合患者的电刺激。 由于患者参数位于内部，所以可以更换系统的外部部分以提供外部替换处理器，并可能为患者提供新型的程序，而无需重新编程耳蜗刺激系统。
-
7.发明授权Dual cochlear/vestibular stimulator with control signals derived from motion and speech signals 有权具有来自运动和语音信号的控制信号的双耳蜗/前庭刺激器公开(公告)号：US07225028B2
公开(公告)日：2007-05-29
申请号：US11134658
申请日：2005-05-20
IPC分类号： A61N1/36
CPC分类号： A61N1/372 , A61N1/36036 , A61N1/37211 , A61N1/3787
摘要： A system for treating patients affected both by hearing loss and by balance disorders related to vestibular hypofunction and/or malfunction, which includes sensors of sound and head movement, processing circuitry, a power source, and an implantable electrical stimulator capable of stimulating areas of the cochlea and areas of the vestibular system.
摘要翻译： 一种用于治疗由听力损失和与前庭功能障碍和/或故障相关的平衡障碍影响的患者的系统，其包括声音和头部运动的传感器，处理电路，电源和可植入的电刺激器，其能够刺激 耳蜗和前庭系统的区域。
-
8.发明授权Spatial decimation stimulation in an implantable neural stimulator, such as a cochlear implant 有权可植入式神经刺激器（例如人工耳蜗植入物）中的空间抽取刺激公开(公告)号：US07039466B1
公开(公告)日：2006-05-02
申请号：US10833427
申请日：2004-04-28
IPC分类号： A61N1/36
CPC分类号： A61N1/36036
摘要： A cochlear implant system, or other neural stimulation system, has the capability to stimulate fast enough to induce stochastic neural firing so as to restore “spontaneous” neural activity. The stimulation rate applied to the more distally-located electrodes of an electrode array connected to the implant system is reduced from the stimulation rate applied to the more proximally-located electrodes. Thus, in the case of a cochlear implant system, the apically-located regions within the cochlea are stimulated at a reduced rate in order to conserve power. Pulse widths of the reduced-rate pulses may further be increased, and amplitudes reduced, to further conserve power. As needed, a low-level random conditioner stimulation signal may be applied to the apical regions of the cochlea in order to ensure the occurrence of random neural firings.
摘要翻译： 耳蜗植入系统或其他神经刺激系统具有刺激足够快以诱导随机神经发射以恢复“自发”神经活动的能力。 施加到连接到植入系统的电极阵列的更远端位置的电极的刺激速率从施加到更靠近位置的电极的刺激速率减小。 因此，在耳蜗植入系统的情况下，以降低的速率刺激耳蜗内的顶部定位的区域以节省功率。 降低速率脉冲的脉冲宽度可以进一步增加，并且幅度减小，以进一步节省功率。 根据需要，可以将低级随机调节器刺激信号应用于耳蜗的顶端区域，以确保随机神经发射的发生。
-
公开(公告)号：US6157861A
公开(公告)日：2000-12-05
申请号：US202751
申请日：1998-12-15
申请人： Michael A. Faltys , Gerald E. Loeb
发明人： Michael A. Faltys , Gerald E. Loeb
CPC分类号： A61N1/36032
摘要： A self-adjusting implantable cochlear implant system (46) includes an implant portion (50) and an external portion (53). The system provides a device and a way to objectively determine selected psychophysical parameters, such as stimulation threshold, comfort level and loudness resolution, used by the implant portion, which includes an implantable cochlear stimulator (ICS), as it carries out its stimulation function. The input to the system is an electrical stimulation. The outputs of the system include a middle ear reflex (MER) and evoked potentials, such as a compound action potential (CAP) along the auditory/cerebral pathways, both of which are sensed using objective measurement techniques and tools. In accordance with one embodiment, the adjustment process uses the MER for determining a coarse threshold value, and then (using such coarse threshold value as a starting point) uses evoked potentials to determine a more precise o fine threshold value, thereby zeroing in on a desired threshold. Such zeroing-in method is preferably carried out using implanted circuitry (e.g., included as part of the ICS), which implanted circuitry uses an implanted middle ear electrode (54) and a cochlear electrode (56), along with appropriate amplification (58, 64), filtering (60, 66) and processing circuitry (62, 68, 67), to respectively determine the MER response and evoked potentials. Another embodiment uses the presence or absence of the MER to adjust the intensity of electrical stimulation continuously and automatically, thereby relieving the patient from having to perform slow and tedious manual adjustments of the loudness control of a speech processor used with the ICS.
摘要翻译： PCT No.PCT / US97 / 10590 Sec。 371 1998年12月15日第 102（e）1998年12月15日日期PCT 1997年6月19日PCT公布。 公开号WO97 / 48447 日期1997年12月24日自动调整植入式耳蜗植入系统（46）包括植入部分（50）和外部部分（53）。 该系统提供了一种装置和一种客观地确定植入部分（包括植入式耳蜗刺激器（ICS））所使用的选择的心理物理参数（例如刺激阈值，舒适度和响度分辨率）的方式，因为它执行其刺激功能。 系统的输入是电刺激。 系统的输出包括中耳反射（MER）和诱发电位，例如沿着听觉/脑通路的复合动作电位（CAP），这两者都使用客观测量技术和工具进行感测。 根据一个实施例，调整过程使用MER来确定粗阈值，然后（使用这样的粗阈值作为起始点）使用诱发电位来确定更精确的精细阈值，从而使 所需阈值。 这种归零方法优选地使用植入电路（例如，作为ICS的一部分包括在内），该植入电路使用植入的中耳电极（54）和耳蜗电极（56）以及适当的放大（58， 64），滤波（60,66）和处理电路（62,68,67），以分别确定MER响应和诱发电位。 另一个实施例使用MER的存在或不存在来连续和自动地调节电刺激的强度，从而减轻患者不必执行与ICS一起使用的语音处理器的响度控制的缓慢且乏味的手动调节。
-
10.发明授权Implantable device with improved battery recharging and powering configuration 失效具有改进的电池充电和供电配置的可植入设备
公开(公告)号：US6067474A
公开(公告)日：2000-05-23
申请号：US126615
申请日：1998-07-31
IPC分类号： A61F2/02 , A61F2/18 , A61F11/00 , A61N1/08 , A61N1/36 , A61N1/375 , A61N1/378 , H01M2/10 , H01M4/02 , H01M6/10 , H01M10/04 , H01M10/34 , H01M10/46 , H02J7/00 , H02J7/02 , H02J17/00 , A61N1/34
CPC分类号： A61N1/08 , A61N1/36032 , A61N1/375 , A61N1/3787 , H01M10/0436 , H01M10/46 , H01M4/02 , H02J7/025 , H01M10/345 , H01M2/1022 , H01M2/1066 , H01M2004/025 , H01M6/10
摘要： An implantable system, such as a neural stimulator or a cochlear implant system, includes a rechargeable battery configuration having improved recharging and lifetime characteristics. The battery is housed within the implant's case and has first and second electrode plates. Each electrode plate has a plurality of slits that extend across a substantial portion of the plate's surface area. The slits in the electrode plates reduce the magnitude of eddy currents induced in the plates by external ac magnetic fields allowing faster battery recharging times. Alternatively, the electrode plates are wrapped in a spiral configuration such that, in the plane of the spiral, the electrode plates have a small cross-sectional area and no closed current loops. Additionally, the implant device may be housed in a case formed of a high-resistivity material and a circuit included in the implant device is configured to avoid large current loops that would result in eddy current heating. As a backup option, the circuitry of the implant device may optionally be powered from an external battery that inductively couples energy to the same coil that is used to charge the internal battery. In one embodiment, the implantable system is partitioned into first and second implantable cases, each having electrical circuitry therein, and only one having a rechargeable power source therein, facilitating its subsequent replacement for repair or upgrading purposes. The two cases are coupled together when the system is in use. Coupling is achieved either magnetically and/or with a detachable electrical cable. In one embodiment, power is transferred from one implant case to the other using a 3-phase transmission scheme.
摘要翻译： 诸如神经刺激器或人工耳蜗植入系统的可植入系统包括具有改善的再充电和寿命特性的可再充电电池配置。 电池容纳在植入物壳体内并具有第一和第二电极板。 每个电极板具有延伸穿过板的表面区域的大部分的多个狭缝。 电极板中的狭缝通过外部交流磁场减小板中感应的涡流的大小，从而允许更快的电池充电时间。 或者，电极板被卷绕成螺旋构造，使得在螺旋的平面中，电极板具有小的横截面积并且没有闭合电流环路。 另外，植入装置可以容纳在由高电阻率材料形成的壳体中，并且包括在植入装置中的电路被配置为避免将导致涡流加热的大电流环路。 作为备用选项，植入装置的电路可以可选地由外部电池供电，外部电池将能量耦合到用于对内部电池充电的相同线圈。 在一个实施例中，可植入系统被划分成第一和第二可植入壳体，每个壳体具有电路，并且只有一个在其中具有可再充电的电源，便于其随后的修理或升级目的的更换。 当系统使用时，这两种情况耦合在一起。 通过磁性和/或可拆卸电缆实现耦合。 在一个实施例中，使用3相传输方案将功率从一个植入壳体传送到另一个。
-
-
-
-
-
-
-
-
-
搜索结果
84 条记录 (耗时 0.025 秒)
