US11333848B2
A four-piece optical lens system includes, in order from the object side to the image side: a stop; a first lens element with a positive refractive power; a second lens element with a negative refractive power; a third lens element with a positive refractive power; a fourth lens element with a negative refractive power, wherein a focal length of the first lens element and the second lens element combined is f12, a focal length of the third lens element is 13, and they satisfy the relation: 0.6
US11333847B2
An optical element driving mechanism is provided, including a movable part for connecting an optical element; a fixed part, wherein the movable part can move relative to the fixed part; a driving assembly for driving the movable part to move relative to the fixed part; and a supporting assembly, wherein the movable part can move relative to the fixed part in multiple dimensions via the supporting assembly.
US11333843B2
A four-piece dual waveband optical lens system includes, in order from the object side to the image side: a stop; a first lens element with a positive refractive power having an object-side surface being convex near an optical axis, an image-side surface being convex near the optical axis; a second lens element with a negative refractive power having an object-side surface being concave near the optical axis, an image-side surface being convex near the optical axis; a third lens element with a positive refractive power having an object-side surface being concave near the optical axis, an image-side surface being convex near the optical axis; a fourth lens element with a negative refractive power having an object-side surface being convex near the optical axis, an image-side surface being concave near the optical axis, which has a short length and good performance without re-focusing in visible light and infrared dual waveband.
US11333842B2
A high-density optical module system of the present invention comprises: a multi-tier housing assembly, multiple sliding tray assemblies engaged inside each of the multi-tier housing assembly and is moveable inwardly and outwardly within the multi-tier housing assembly with the handle bar; and a multiple rows of the multi-port modules arranged in horizontal arrays containing plural ports connected to the cable adaptors, wherein the multi-port modules are fastened into the sliding tray assembly. The height of the high-density optical module system is approximately 1RU (19 inches) containing at least 216 LC or 108 SC multiple connector ports.
US11333837B2
An optical communication system includes a first communication system to communicate first information from a controller to a truck and a second communication system to communicate second information. The first communication system includes a first light emitter to output the first information, a first optical fiber to transport the light output from the first light emitter while letting the light leak therefrom, and a first light receiver to receive the light leaking from the first optical fiber. The second communication system includes a second light emitter to output second information, a second optical fiber to transport the light output from the second light emitter and input to the second optical fiber at some point along the second optical fiber, and a second light receiver to receive the light transported over the second optical fiber.
US11333833B2
There is provided an optical axis alignment mechanism between the laser oscillator and the optical fiber. The laser oscillator emits laser light, which then emerges from the emission end of the optical fiber via the axis alignment mechanism. Part of the laser light is received on the light-receiving surface of the CCD camera of a laser light evaluator. Thus, the laser light evaluator acquires a light intensity distribution. The light intensity distribution is used by the optical axis alignment mechanism to align the axis of the laser oscillator with the axis of the optical fiber.
US11333832B2
An optical functional device includes a package case accommodating an optical functional element, an input optical fiber, and an output optical fiber. The optical functional device includes a first reflecting surface that reflects input light output from the input optical fiber to an optical path of output light, a second reflecting surface that reflects the input light to the optical functional element, and a third reflecting surface that reflects the output light in a direction in which the output light becomes further away from an optical axis of the input optical fiber. An optical axis of a leaked light beam transmitted through the second reflecting surface after being reflected by the first reflecting surface or an extension line of the optical axis in an optical propagation medium does not include a portion that is aligned with an optical axis of the output light reflected by the third reflecting surface.
US11333831B2
An optical circuit for routing a signal includes a coupler and first and second waveguides. The coupler has an input for the signal and has first and second outputs. The first waveguide has a first optical connection to the first output, and the second waveguide has a second optical connection to the second output. Both waveguides have the same propagation length. The first and second waveguides include different widths at the respective optical connections to the respective outputs. This coupler can be used with another input couplers, two additional waveguides, and two 2×2 output couplers to provide a 90-degree hybrid for mixing signal light and local oscillator light in a coherent receiver or the like.
US11333830B2
The present application discloses a polarization beam splitter (PBS). The PBS includes a silicon substrate and a planar structure formed thereon characterized by an isosceles trapezoid shape with a first parallel side and a second parallel side connected by two tapered sides. The first parallel side has longer width than the second parallel side, both of which is separated by a length no greater than 100 μm along a line of symmetry bisecting the pair of parallel sides. The PBS further includes a pair of input ports coupled to the first parallel side and a pair of output ports coupled to the second parallel side. The planar structure is configured to receive an input light wave of any wavelength in C-band via one input port and split to a TE-mode light wave and a TM-mode light wave respectively outputting to the pair of output ports.
US11333822B2
A single edge lit lighting module produces bi-lobed light distributions which provide targeted control of light output. The compact form factor of module embodiments having narrow width are particularly well-suited for use in linear lighting fixtures for suspended and downlighting configurations typically used to illuminate floors and/or ceilings. Embodiments of the single edge lit lighting module utilize reflectors in combination with light guides having volumetric light scattering properties and surface features to control peak intensities, output angles, and shapes of the two light output lobes. A variety of light distributions can be achieved including symmetrical distributions conventionally achieved by double edge lit modules. Further embodiments utilize selective alignment of light guide with reflector to achieve different light distributions thereby providing a fixture assembler with more design choices without need of additional components.
US11333810B2
A system of networked controllers includes one or more switchable optical filters, and the switchable optical filters are photochromic and electrochromic. The system also includes a master controller, and one or more slave controllers operably connected to the one or more switchable optical filters. At least one of the one or more slave controllers is communicatively coupled to the master controller. The master controller is configured to transmit a switching command to the at least one of the one or more slave controllers. Each slave controller is operable, in response to receiving the switching command, to cause a corresponding switchable optical filter to transition from a first state to a second state.
US11333808B2
A light filtering assembly is installed in a lens module, including a fixed mount having a hollow part, a light filter at the hollow part, a shutter annularly disposed on the light filter, and a binding element. The hollow part is annularly formed by a support part extending from the fixed mount toward the hollow part. A first binding space is formed between the support part and the fixed mount, extending the outer periphery of the light filter and the shutter into the first binding space. An adhesive material is injected into the first binding space, and is then cooled down to form the binding element in the first binding space, so as to stop the light filter and the shutter at the hollow part as well as fix the light filter and the shutter on the fixed mount.
US11333801B2
Provided are a miniature endoscopic probe and a multi-photon endoscopy including the same.
US11333792B1
Systems and methods for assessing seismic risk. The system and methods disclose deriving a model that is used to assess seismic risk of operations at a given location. A first location is identified for which at least one training seismic risk value is known from independent sources. A plurality of training input parameters associated with the first location is received. The at least one training seismic risk value is received. A process model is derived that relates the plurality of training input parameters to the at least one training seismic risk value by determining influence values of the training input parameters. A second location is identified for which a seismic risk is to be determined. A plurality of working input parameters associated with the second location is received. The process model is applied to the plurality of working input parameters to determine a seismic risk value at the second location.
US11333791B2
The present disclosure relates to a method of calculating the radiogenic heat production (RHP) of a geophysical structure, wherein there is provided at least one geophysical parameter of the geophysical structure, the method including inverting the at least one geophysical parameter to estimate the RHP of the geophysical structure.
US11333790B2
The invention relates to a method of setting a plurality of part regions of a desired protected zone, in which a) the positions of a plurality of monitoring units are detected, with each monitoring unit detecting a detection zone; b) a maximum size of each detection zone is determined; c) the desired protected zone is fixed in a graphical user interface; d) the part regions to be monitored by the respective monitoring units are fixed with reference to the positions of the monitoring units, to the maximum size of the detection zones and of the desired protected zone; and e) the part regions are assigned to the respective monitoring units.
US11333786B1
Systems and methods for locating buried utilities in conjunction with associated electromagnetic marker devices are disclosed. A marker device may include a marker device antenna and an electronic circuit operatively coupled to the marker device antenna. The electronic circuit may include at least two resonant circuits, including a first resonant circuit formed in combination with the marker device antenna for receiving an excitation signal at a first frequency from a marker excitation device. The received excitation signal may be converted into a power supply by a power circuit for powering the electronic circuit. Responsive to the received excitation signal, a processing element provided in the electronic circuit may generate an output signal at a second frequency, which is substantially different from the first frequency. The generated output signal may be tuned by a second resonant circuit and provided to the marker device antenna.
US11333779B2
Systems and methods for geochemical sampling grid locations on a seafloor. At least one of the methods includes generating, using received seismic data, an image representing an interpretation of a seafloor horizon surface; extracting, from the image and based on the seismic data, one or more discontinuity attributes of the seafloor horizon surface; extracting, from the image and based on the seismic data, one or more amplitude attributes of a window extending below the seafloor horizon surface; combining the one or more discontinuity attributes and the one or more amplitude attributes; and selecting, using the image and based at least partly on the combining, one or more locations of the seafloor horizon surface for sampling.
US11333769B2
A system and method generates a phase scintillation map that is utilized to de-weight satellite signal observations from GNSS satellites. One or more base stations each assign an index value to one or more GNSS satellite in view, where the index value indicates an adverse effect of ionospheric scintillation on signals received from the GNSS satellite. The values and identifiers may be transmitted to a server. The server utilizes the received information to generate the phase scintillation map that may include one or more scintillation bubbles, wherein a location of each scintillation bubble is based on the received information. The phase scintillation map is transmitted to one or more rovers. The rover determines if a pierce point associated with a selected GNSS satellite in view of the rover falls within the boundaries of a scintillation bubble. If so, satellite signal observations from the selected GNSS satellite are de-weighted.
US11333765B2
Provided is a distance measuring method and device for selecting an optimum peak detection signal from among a plurality of peak detection signals, based on a level of at least one of a plurality of amplified electrical signals, and measuring a distance to an object by using the selected optimum peak detection signal.
US11333762B2
Among other things, a method includes receiving first LiDAR point cloud information from a first LiDAR device and second LiDAR point cloud information from a second LiDAR device, generating third point cloud information according to merging the first and second LiDAR point cloud information, and operating the vehicle based upon the third LiDAR point cloud information.
US11333760B2
An optical time of flight system includes a transmitter and a receiver. The transmitter is configured to generate a modulation signal having a modulation signal frequency that varies as a function of time, generate an optical waveform with amplitude modulation corresponding to the modulation signal, and direct the optical waveform toward a field of view (FOV). The receiver is configured to receive the optical waveform reflected off of an object within the FOV and determine a distance to the object based on a time of flight from the transmitter to the object and back to the receiver.
US11333755B2
An acoustic detection system for detecting at least partly submerged targets in a sensitive area defined with respect to an infrastructure, the detection system includes at least one multistatic detection group, each multistatic detection group defining a detection area, and comprising: a submerged transmitter emitting at low frequencies; a plurality of submerged receivers comprising at least two receivers, each receiver of a given group forming, with the transmitter of the group, a bistatic pair, each bistatic pair generating an elementary detection area surrounding a blind zone, the detection area of the group being formed by all of the elementary detection areas of the receivers of the group, the receivers being arranged in at least one layer. For at least one group of the system, the form described by the receivers of at least one layer of the group is an at least partly circular form of given radius, the inter-receiver distance between two adjacent receivers of the layer depending on the distance between the transmitter of the group and the rectilinear segment linking the adjacent receivers of the layer, called reference transmitter-receiver distance.
US11333750B2
A method and system for determining a position of a non-cooperative object using a reflected signal from Secondary Surveillance Radar (SSR) system is disclosed. The method enables the ownship to detect a non-cooperative intruder, an aircraft which does not have a functioning transponder. The position and altitude of the non-cooperative intruder are determined from reflected signals by a phased array antenna or mechanically scanned directional antenna (MSDA) to perform tracking and avoidance of the non-cooperative object. In the case that a phased array antenna or MSDA is not available, a co-altitude assumption is applied to conservatively determine an avoidance area around the non-cooperative object, which defines coordinates to be tracked and avoided by the ownship.
US11333742B2
The present invention discloses a laser range finder for two-color switching display, comprising a monocular telescope, a laser light emitting system, a laser receiver and an OLED liquid crystal display (LCD) imaging system, wherein the monocular telescope comprises an objective lens, a roof half penta prism, a cemented prism, an eyepiece and an LCD unit; laser light emitted by the laser light emitting system is emitted onto an object to be measured, and the reflected back laser light is received by the laser receiver after passing through the objective lens, the roof half penta prism and the cemented prism; and light emitted by the OLED LCD imaging system is imaged on the focal plane of the eyepiece through the cemented prism. The present invention can achieve two-color display of the laser range finder, meeting the requirements for use in a variety of conditions.
US11333740B2
Aspects of the present disclosure involve systems, methods, and devices for determining specular reflectivity characteristics of objects using a Lidar system of an autonomous vehicle (AV) system. A method includes transmitting at least two light signals directed at a target object utilizing the Lidar system of the AV system. The method further includes determining at least two reflectivity values for the target object based on return signals corresponding to the at least two light signals. The method further includes classifying specular reflectivity characteristics of the target object based on a comparison of the first and second reflectivity value. The method further includes updating a motion plan for the AV system based on the specular reflectivity characteristics of the target object.
US11333736B2
In the present invention, to make it possible to enhance the accuracy of positioning in an area not reached by a GNSS signal: a first position of a host device is estimated; the error of the first position is estimated; from a second device, other device information is received that includes a second position of the second device and a second error of the second position that have been estimated by the second device; and if the second error is smaller than the first error, the first position and first error are corrected on the basis of the other device information.
US11333733B2
In a method and apparatus for recording a magnetic resonance (MR) data record using multiple reception coils, the data of the MR data record contain measurement signals of at least two image data records respectively from at least two slices. The MR data record is acquired in a sequence having an excitation phase, an evolution phase, readout of a first echo signal while a first read gradient is being applied, application of at least one shift gradient in a slice-selection direction, and readout of at least one further echo signal while a further read gradient is applied. The shift gradient is positioned so as to cause a shift of at least one further image data record generated from the further echo signal or signals relative to the first image data record generated from first echo signals.
US11333732B2
The invention provides for a magnetic resonance imaging system (100, 300). The execution of machine executable instructions causes a processor (130) controlling the magnetic resonance imaging system to control (200) the magnetic resonance imaging system to acquire the magnetic resonance imaging data (144) using pulse sequence commands (142) and reconstruct (202) a magnetic resonance image (148). Execution of the machine executable instructions causes the processor to receive (204) a list of suggested pulse sequence command changes (152) by inputting the magnetic resonance image and image metadata (150) into an MRI artifact detection module (146, 146′, 146″). The MRI artifact detection module comprises at least one neural network, which has been trained using images from failed magnetic resonance imaging protocols and/or magnetic resonance data extracted from the magnetic resonance imaging protocols labeled as failed accessed from a log file (312) which logs the execution of previous magnetic resonance imaging protocols. Execution of the machine executable instructions further causes the processor to receive (206) a selection of a chosen pulse sequence command change (158) from the list of suggested pulse sequence command changes. Execution of the machine executable instructions further causes the processor to modify (208) the pulse sequence commands using the chosen pulse sequence command change.
US11333729B2
Systems and methods for magnetic resonance imaging (“MRI”) of multiple different nuclear spin species using the same radio frequency (“RF”) coil are described. Generally, multiple different nuclear spin species are imaged using the same RF coil by using an MRI system whose magnetic field can be rapidly ramped between a number of different, and arbitrary, magnetic field strengths. The magnetic field of this MRI system can be ramped to different values in reasonable amounts of time (e.g., in a time frame that is feasible within an imaging study).
US11333727B2
An apparatus for providing a B0 magnetic field for a magnetic resonance imaging system. The apparatus includes at least one permanent B0 magnet to contribute a magnetic field to the B0 magnetic field for the MRI system and a ferromagnetic frame configured to capture and direct at least some of the magnetic field generated by the B0 magnet. The ferromagnetic frame includes a first plate configured to support the at least one permanent B0 magnet and a first post attached to the first plate using a first connection assembly, wherein the first connection assembly includes a first connector that connects the first post and the first plate and a second connector attached to the first connector.
US11333726B2
Methods and apparatus for operating a low-field magnetic resonance imaging (MRI) system to perform diffusion weighted imaging, the low-field MRI system including a plurality of magnetics components including a B0 magnet configured to produce a low-field main magnetic field B0, at least one gradient coil configured to, when operated, provide spatial encoding of emitted magnetic resonance signals, and at least one radio frequency (RF) component configured to acquire, when operated, the emitted magnetic resonance signals. The method comprises controlling one or more of the plurality of magnetics components in accordance with at least one pulse sequence having a diffusion-weighted gradient encoding period followed by multiple echo periods during which magnetic resonance signals are produced and detected, wherein at least two of the multiple echo periods correspond to respective encoded echoes having an opposite gradient polarity.
US11333716B2
To make an excessive power receiving request by a sink when a USB Type-C legacy cable is used. An electronic device includes a first and second terminals connected to a cable, a detection circuit for detecting the voltage of the first and second terminals, and a first or second terminal detected by the detection circuit. It is provided with a controller that determines the type of cable based on the terminal voltage and confirms the power supply capacity of the external electronic device connected via the cable according to the type of cable.
US11333710B2
In a method for estimating a voltage of a battery a given battery model (BM) is provided, wherein the given battery model (BM) is a single particle model. A C-rate of the battery is determined. The battery model (BM) is adapted based on the C-rate. The voltage of the battery is estimated by means of the adapted battery model (BM).
US11333701B2
A current supply device includes a multiplexed digital bus, an output terminal, and a group of power supplies connected in parallel between the multiplexed digital bus and the output terminal. The group of power supplies are controlled via the multiplexed digital bus such that a combined output current of the group of power supplies is applied to the output terminal.
US11333700B2
According to one embodiment, an inspection apparatus of a semiconductor device includes a first probe configured to contact a first portion of the semiconductor device, a conductive member configured to oppose a second portion of the semiconductor device, and a detector configured to apply a first voltage between the semiconductor device and the first probe, to apply a conductive member voltage between the semiconductor device and the conductive member, and to detect a current flowing in the first probe. The first voltage has a first polarity of one of positive or negative when referenced to a potential of the semiconductor device. The conductive member voltage has a second polarity of the other of positive or negative when referenced to the potential of the semiconductor device.
US11333699B2
A method for characterizing a fault in a transmission line network, the method includes the steps of: obtaining a first measured time reflectogram Rm from a signal previously injected into the network, obtaining a second time reflectogram Rs corresponding to the network in the absence of faults, determining the time difference Rref between the first measured time reflectogram Rm and the second time reflectogram Rs, identifying, in the time difference Rref, an amplitude peak characterizing the presence of a fault and its time abscissa indicating the position of the fault, simulating a plurality of time reflectogram hypotheses each corresponding to the network comprising a fault at the identified position, each hypothesis being associated with a different value of at least one parameter characteristic of the fault, selecting the time reflectogram hypothesis closest to the time difference Rref.
US11333685B1
Switching of particular inputs in a signal processing channel permits an independent evaluation of that signal processing channel, in a system where there are at least two signal processing channels, one of which is able to be calibrated while the other of which is measuring current in a shunt. Switching a controlled current through a shunt, the controlled current being small in value compared with an overall current being measured, permits yet another independent evaluation of the shunt.
US11333682B2
A probe includes a first rod having a first axis and a second rod having a second axis. A first end of the first rod is connected to a first end of the second rod to form an angle that maintains a “total internal reflection” effect for waves propagating through the probe. A second end of the second rod includes a prong facilitating attachment of the probe to a housing block. The first axis and the second axis define a plane. A second end of the first rod includes a tapered face formed perpendicular to the plane. The tapered face is sufficiently flat to make planar contact with a portion of a component under study. A support is formed in the plane and connected to the second rod. A second end of the support includes a connector to facilitate attachment of the probe to the housing block.
US11333681B2
A cantilever probe head includes a support ring associated with a PCB board and a plurality of contact probes, protruding from the support ring in a cantilever manner and being held by a support associated with the support ring. Each contact probe has a rod-like body having a longitudinal axis inclined with respect to a reference plane corresponding to a plane of a wafer of devices under test by the cantilever probe head, as well as at least one first end portion, provided in a first probe section protruding from the support in the direction of the wafer of devices under test, the first end portion being bent with respect to the longitudinal axis starting from a bending point and ending with a contact tip of the contact probe able to abut onto a contact pad of a device under test of the wafer.
US11333678B2
A method for offset calibration of a rotation rate sensor signal of a rotation rate sensor. In a first step, an ascertainment is made that the rotation rate sensor is in an idle state. In a second step, after the first step, a filter parameter is determined as a function of the measured rotation rate sensor values, measured in the idle state, of the rotation rate sensor. In a third step, after the second step, a filtered measured rotation rate sensor value is determined with the aid of the filter parameter. An offset is determined with the aid of the filtered measured rotation rate sensor value.
US11333677B2
The present application includes a computer-implemented method for detecting a tamper event. The method includes a step of receiving, from one or more sensors on an integrated module, data indicating one or more of light, acceleration, magnetic field, rotation, temperature, pressure, humidity, and audio. The method also includes a step of transmitting, to a microcontroller/evaluation engine coupled to the integrated module, the received data from the one or more sensors. The method further includes a step of determining, via the microcontroller, the received data exceeding one or more configurable thresholds of the tamper event. The method even further includes a step of assigning, via the microcontroller, a score associated with each of the one or more configurable thresholds being exceeded by the received data. The method yet even further includes a step of collecting, via the microcontroller, an aggregate total based on the assigning step. The method still further includes a step of evaluating, via the controller, the aggregate total in view of a predetermined alarm threshold of the tamper event.
US11333673B2
Methods are described for determining the amount of metabolites of leflunomide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying teriflunomide in a sample.
US11333671B2
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect C—C motif chemokine 16, C—C motif chemokine 14, and Tyrosine-protein kinase receptor UFO as diagnostic and prognostic biomarker assays in renal injuries.
US11333669B2
The invention provides mass spectrometry methods, compositions and systems which enable a unique platform for analyte quantitation accessing very high degrees of multiplexing and accurate quantification, particularly well-suited for a range of quantitative analysis for proteomics applications. Embodiments of the present methods and systems combine isotopic coding agents characterized by very small differences in molecular mass with mass spectrometry methods providing large resolving power to provide relative or absolute analyte quantification in a large number of samples.
US11333663B2
A tag for detecting an analyte can include a radio frequency identification tag including a sensor portion, the sensor portion configured to change resistivity when the radio frequency identification tag contacts or interacts with an analyte, whereby the resistivity change alters an output of the radio frequency identification tag, wherein the sensor portion includes a circuit, and wherein the sensor portion is configured to activate the circuit or deactivate the circuit when contacted or having interacted with the analyte, where the sensor portion includes a plurality of carbon nanotubes associated with a chemically-degradable polymer. In certain embodiments, the chemically degradable polymer can be a metallo-supramolecular polymer.
US11333662B2
The present invention relates to a method for determining the potency of a supernatant of a mammalian cell culture to be used in the treatment of an inflammatory condition.
US11333661B2
A detection analyzer including a first sample input/output element, a second sample input/output element, a sample compartment, a vibration platform, a vibration generator, a data acquisition system, a laser converter, and a data display. The first sample input/output element and the second sample input/output element are each connected to the sample compartment; the vibration platform is located inside the sample compartment; the vibration generator is located outside the sample compartment, and the vibration platform is connected to the vibration generator; the data acquisition system is located outside the sample compartment, and is connected to the vibration platform; and the data display is connected to the data acquisition system.
US11333658B2
A method of detecting a urine test strip from a photographed image of the urine test strip is disclosed. The disclosed method of detecting a urine test strip includes: receiving input of a urine test strip image, which is a photographed image of a urine test strip including a first and a second marker; detecting a first and a second marker image within the urine test strip image; detecting an area between the first and second marker images within the urine test strip image; and detecting a reagent pad and a colorimetric table in the urine test strip image by matching an area of interest, which represents a position of the reagent pad and the colorimetric table in the urine test strip image, with the area between the first and second marker images.
US11333657B2
A method or device for assaying physiological gas levels in a human, comprising: repeatedly measuring a gas in samples of breath or blood, or continuously measuring the gas through the skin or fingernail, while he or she holds his or her breath for a specified time interval (BHt) before each measurement, wherein these time intervals are selected from the group consisting of BHt=0, 4-6, 20-25 and 35-40 seconds, and recording the results to form a series of values including at least one measurement at BHt=35-40 which is treated as representing the average gas level in all the tissues of the body (T) at that time, to determine if the individual is net inhaling, net exhaling or in equilibrium with the gas.
US11333650B2
This disclosure relates methods and systems for determining asphaltene inhibitor properties. For example, one embodiment provides a method for determining a content of disaggregated asphaltene in an inhibited crude oil. The method includes measuring the dielectric constant of a sample of the crude oil, the sample having a first concentration of an asphaltene inhibitor; providing a first dielectric correction factor for the first concentration of the asphaltene inhibitor; calculating, e.g., by a computing device, a first corrected dielectric constant of the sample having the first concentration, using the first dielectric correction factor; and determining the content of disaggregated asphaltene in the first crude oil sample, based on the first corrected dielectric constant. Methods for inhibiting asphaltene aggregation in crude oil are also provided.
US11333622B2
A method for determining a direct current impedance of a transducer may include receiving an input signal indicative of an electrical power consumed by the transducer and calculating, by a thermal model of the transducer, the direct current impedance based on the electrical power.
US11333619B2
A measurement X-ray CT apparatus calibrates a geometrical positional relationship between a focus of an X-ray source, an X-ray detector, and a rotation center of a rotating table in advance. The measurement X-ray CT apparatus then obtains projection images by irradiating the object to be measured with X-rays to perform a CT scan, and generates a three-dimensional image of the object to be measured by CT reconstruction of the projection images. The measurement X-ray CT apparatus further includes a reference frame that is made of a material and has a structure less susceptible to environmental changes, and sensors that are located on the reference frame and intended to successively obtain calibration values of the geometrical positional relationship between the focus of the X-ray source and the X-ray detector during the CT scan. The calibration values are used as parameters of the CT reconstruction.
US11333613B2
An apparatus for use in inspecting a wire segment is provided. The apparatus includes a guide tube sized to receive the wire segment, and an array of mirrors positioned about the guide tube. Each mirror in the array is oriented such that a reflection of the wire segment in the array of mirrors forms a circumferential view of at least a portion of the wire segment, and such that the reflection from each mirror is within a field of view from a single vantage point.
US11333610B2
The invention provides a percarboxylic acid concentration-determining device capable of determining the concentration of percarboxylic acid contained in an aqueous solution for chemical sterilization or disinfection that contains a percarboxylic acid as an active ingredient; and an indicator solution for use in preparing the device. The indicator solution contains a starch, an iodide, a thiosulfate, a water-soluble organic solvent, and water, with the starch, the iodide, the thiosulfate, and the water-soluble organic solvent being present in the following proportions, based on the total amount taken as 100 mass %: (a) starch: 0.01 to 5 mass %; (b) iodide: 0.01 to 5 mass %; (c) thiosulfate: 0.01 to 10 mass %; and (d) water-soluble organic solvent: 0.1 to 40 mass %, wherein the total amount of (a), (b), and (c) is greater than 0.6 mass %.
US11333609B2
The present invention relates to a real-time detection device for municipal solid waste components in an incinerator. The real-time detection device includes: an optical fiber sensor, which faces combustion flame of municipal solid waste combustion region through an observation hole in the incinerator; a spectrometer, which is used for receiving optical signal of the optical fiber sensor; an industrial personal computer, which is used for receiving data of the spectrometer and outputting the municipal solid waste components according to a municipal solid waste component detection program; the municipal solid waste component detection program obtains combustion flame spectral information of municipal solid waste in the incinerator by utilizing the optical fiber sensor and the spectrometer, and detects the municipal solid waste components in real time based on combustion flame spectrum of a single waste component. The present invention further relates to a real-time detection method for municipal solid waste components in an incinerator. Compared with manual classified sampling and detection, the device and method provided by the present invention have the advantages of high efficiency, rapidness, accuracy, capability of being updated in real time; and can realize stable combustion of the municipal solid waste in the incinerator, and reduce emission of pollutants and realize efficient and clean utilization of the municipal solid waste.
US11333605B2
Disclosed is a sample measurement device including a light applicator configured to apply a light to a sample so as to generate light from a particle in the sample; an optical block in which a plurality of prisms are fixed, each of the plurality of prisms including a light entry surface which allows entry thereinto of the light generated from the particle in the sample, a reflection surface configured to selectively reflect a part of the light having entered the light entry surface, and a light outputting surface configured to output the light reflected by the reflection surface; and a light receiver configured to receive the light outputted from the light outputting surface of each of the plurality of prisms.
US11333597B2
A system, an apparatus, and a method are provided for a modular flow cytometer with a compact size. In one embodiment, the modular flow cytometry system includes the following: a laser system for emitting laser beams; a flow cell assembly positioned to receive the laser beams at an interrogation region of a fluidics stream where fluoresced cells scatter the laser beams into fluorescent light; a fiber assembly positioned to collect the fluorescent light; and a compact light detection module including a first image array having a transparent block, a plurality of micro-mirrors in a row coupled to a first side of the transparent block, and a plurality of filters in a row coupled to a second side of the transparent block opposite the first side.
US11333588B1
Matrix-assisted methods and compositions, including those based on solutions containing low melting agarose, to prepare intact organs and other samples for super resolution imaging by microscopy, and more particularly, lightsheet microscopy.
US11333586B2
A smear staining machine and a smearing control method and device thereof. The viscosity of the test sample is used for guiding the configuration of at least on smearing parameter. Since the viscosity of the test sample presents multiple influences of many effecting parameters, it is more suitable for presenting the characteristics of the test sample. Therefore, better smearing effect could be acquired by referring the viscosity of the test sample to get the smearing parameter.
US11333583B2
An extraction portion which is a piece of a micro sampling chip is safely cut, and the cut extraction portion can be accommodated in a predetermined container without impairing quantitativeness of a sample.
A sample extraction tool comprises a through hole for cutting the extraction portion from the micro sampling chip by bending the micro sampling chip while inserting the extraction portion to the through hole, the sample extraction tool is configured to be attached to an upper portion of a container for accommodating the extraction portion in such a state that the through hole is disposed on an open upper surface of the container.
US11333582B2
The disclosure relates to a microtome having a cutting knife, an object holder mounted on a slide, the slide being movable relative to the cutting knife in a cutting direction and in a thickness defining direction, movement of the slide in the thickness defining direction being performed by a first electric motor controlled by a control unit, movement of the slide in the cutting direction being performed by a second electric motor controlled by the control unit, wherein the control unit is configured to control the movement of the slide in the thickness defining direction and in the cutting direction.
US11333580B2
An anomaly detecting device includes: a singular value decomposition unit configured to perform singular value decomposition of a variance-covariance matrix of a measured value matrix y0 composed of measured values acquired by a plurality of sensors in a time period considered to be normal, to thereby calculate a singular vector U and a singular value matrix S; an anomaly determination unit configured to apply the singular vector U and the singular value matrix S to a measured value matrix yt to be evaluated and which is acquired in an arbitrary time period to determine whether an anomaly is present from a result of application; and an anomalous part identification unit configured to, when the measured value matrix yt is determined to be anomalous, identify an anomalous part based on a diagonal element of a matrix obtained in association with the measured value matrix yt.
US11333578B2
A method and system of providing customizable service for an asset. The method including generating a predictive model for each asset of a fleet, each predictive model based on an operational profile for the asset and including a probability density function associated with the operational durability of the asset, establishing a maintenance strategy associated with the asset, and combining each of the predictive models to generate a compound fleet performance model, the fleet performance model including a combined probability density function. The method also includes collecting actual asset performance and maintenance data to generate actual asset metrics, determining a fleet performance profile based on the actual asset metrics indicative of a health assessment of the fleet, comparing the predicted fleet performance with the actual fleet performance, and ascertaining actionable choices for managing the assets based on a deviation of the predicted and actual fleet performance.
US11333572B2
A method for detecting damage to one or more mobile blades of an impeller of an aircraft engine, includes measuring the speed of the engine, and for each blade acquiring, by a plurality of sensors, measurements of blade-tip passage times; calculating for each sensor, a deflection of the blade tip; extracting a dynamic component of deflection for each of the calculated deflections; detecting the number of functioning sensors; selecting the dynamic components to be processed based on the detecting step; determining, for at least one blade, a variation of the dynamic behavior of the blade for each functioning sensor; and, for each blade for which a variation of the dynamic behavior has been determined, identification of potential damage to the blade.
US11333571B2
The invention provides a dynamic seal test device for cryogenic fluid medium. The dynamic seal test device includes stator unit, rotor unit, slipway, servo motor unit and sensors. The tested seal is installed inside the stator, and the thermal insulation stator and vacuum rotor together form a dynamic seal test structure. The seals and shaft sleeves can be flexibly replaced, which is beneficial to study the influence of different seal types, structure, and seal land configurations on the sealing performance. The servo motor provides power for the rotor and controls the rotation speed. The device greatly improves the thermal insulation capacity to avoid the gasification for the cryogenic fluid medium induced by the heat transfer from environment so that ensuring the stability of the test device.
US11333560B2
A heat-sensitive resistor with a negative or positive temperature coefficient comprises respectively an antimony-doped tin oxide-based resistive element or a carbon black-based resistive element, containing a polymer having a dielectric constant between 2 and 3, a molar mass between 50000 and 150000 g/mol, and a glass transition temperature Tg between 40 and 100° C.
US11333549B2
An avalanche photodiode sensor includes a photoelectric conversion region disposed in a substrate and that converts incident light into electric charge. The avalanche photodiode sensor includes a first region of a first conductivity type on the photoelectric conversion region, and a cathode disposed in the substrate adjacent to the first region and coupled to the photoelectric conversion region. The avalanche photodiode sensor includes an anode disposed in the substrate adjacent to the cathode, and a contact of the first conductivity type disposed in the substrate. An impurity concentration of the first region is different than an impurity concentration of the contact.
US11333547B2
A method at a computing device, the method including obtaining sensor data for a vehicle providing vibration frequency and magnitude; calculating an energy for each of a low frequency passband and a high frequency passband of a bandpass filter pair; finding an energy ratio based on the energy for the low frequency passband and the energy for the high frequency passband; applying weighting constants to each of the energy for the low frequency passband, the energy for the high frequency passband and the energy ratio to calculate a decision variable; and finding that the vehicle is unloaded if the decision variable is below a threshold and finding that the vehicle is loaded if the decision variable is above a threshold.
US11333538B2
An example system is configured for determining properties of a fluid in a conduit. The system includes a mass flow meter including a hollow conduit having an inlet, an outlet, and a wall. The conduit is for conducting the fluid. The system includes a driver coupled to the conduit. The driver is configured for inducing an oscillation in the conduit. The system includes two or more accelerometers coupled to the conduit. The two or more accelerometers are configured for measuring displacement of the conduit. The system includes an electrical permittivity sensor coupled to the conduit. The electrical permittivity sensor is configured for measuring electrical permittivity of the fluid.
US11333537B2
A magnetic flowmeter for measuring a fluid flow includes a flow tube assembly receiving the flow and having a coil with first and second coil wires for receiving a coil current and responsively producing a magnetic field thereby generating an EMF in the fluid representative of a flow rate. An EMF sensor is arranged to sense the EMF and generate an output indicating the flow rate. Current supply circuitry applies a current supply signal to the coil. A load leveling boost supply provides power to the current supply circuitry. In another aspect, power scavenging circuitry recovers power from the coil.
US11333533B2
A grating measuring module includes a light source, a collimating device, a first grating, a second grating, and an image sensing chip. The first grating is arranged on an optical path of the collimating device and the second grating is arranged on an optical path of the first grating. Each of the two gratings comprises a first pattern and a plurality of second patterns locating at the both sides of the first pattern. The first and second gratings can each be attached to an object which may be displaced in relation to another object, so allowing light of a certain pattern to pass depending on the magnitude of the displacement. The image sensing chip arranged on an optical path from the second grating receives light emitted from the light source and forms an image from which a displacement can be calculated and displayed.
US11333532B1
There is provided a light control circuit including a light detector, a frequency detector, an error amplifier, an NMOS driver and a light source. The frequency detector identifies a signal frequency according to detected voltage signals outputted by the light detector and generates a control signal accordingly. The NMOS driver changes a drive current of the light source according to an output of the error amplifier. The error amplifier changes a bandwidth thereof according to the control signal from the frequency detector to regulate a response time of the drive current of the light source.
US11333530B2
In some embodiments, a method can include receiving, by an angle sensor, a first periodic angle signal indicative of an angle of a first magnetic field associated with a first track of a target; receiving, by the angle sensor, a second periodic angle signal indicative of an angle of a second magnetic field associated with a second track of the target; generating an uncorrected absolute angle signal indicative of an absolute angle of the target based on the first and second periodic angle signals; determining an estimated error associated with the uncorrected absolute angle signal based on the first periodic angle signal and the second periodic signal; subtracting the estimated error from the uncorrected absolute angle to generate a corrected absolute angle signal; and providing the corrected absolute angle signal as output of the angle sensor.
US11333528B1
A sensor device includes a first sensor arrangement configured to generate first sensor signals based on sensing a varying magnetic field generated by a pole wheel having a pole wheel pitch, wherein the first sensor signals represent a first differential signal that defines a first measurement value; a second sensor arrangement configured to generate at least one second sensor signal based on sensing the varying magnetic field, wherein the at least one second sensor signal defines a second measurement value that is phase shifted from the first measurement value; and a signal processor configured to detect the pole wheel pitch based on the first measurement value and the second measurement value, and adjust a gain setting of an amplifier circuit based on the detected pole wheel pitch, where the amplifier circuit is configured to amplify the at least one second sensor signal.
US11333519B2
Systems and methods for generating efficient planning routes for vehicles, including autonomous and semi-autonomous vehicles are presented. A route planner may generate dynamic maps and routes that reduces the uncertainty of road-agent environmental and behavioral data in an efficient manner. Route planning may be accomplished using a statistical approach in which known data from one geographic or behavioral feature set may be used and relied upon by a vehicle in another geographical and behavioral context to estimate the environmental and behavioral data relevant to the vehicles current operation.
US11333516B2
Provided is lane guidance system for decreasing the possibility that a user is misled including: a proposed travel route acquisition unit that acquires a proposed travel route of a vehicle; a successive intersection determination unit that determines whether a distance between a first intersection that is a guidance intersection on the proposed travel route and a second intersection that follows the first intersection is within a prescribed distance. Based on the proposed travel route, a travelable lane acquisition unit acquires a travelable lane that the vehicle needs to travel along when entering the first intersection to exit in a specific exiting direction of the first intersection, when the vehicle needs to exit from the first intersection in the exiting direction to travel along the proposed travel route. Before arriving at the first intersection, the lane guidance unit selects and proposes, as a recommended lane from the travelable lane, a lane that the vehicle needs to travel along when entering the first intersection after exiting from the first intersection, a lane that the vehicle needs to travel along when entering the second intersection to exit in a specific exiting direction of the second intersection, when the vehicle needs to exit from the second intersection in the exiting direction to travel along the proposed travel route when the a distance between the first intersection and the second intersection is within a prescribed distance.
US11333510B2
In one example embodiment, a computer-implemented method and system for learning places of interest are disclosed. The method includes learning and storing location information of at least one mobile device; detecting a location where no movement of the at least one mobile device has occurred over a pre-determined duration of time; determining whether the detected location is classified as a location of interest based on a predefined criteria; and clustering the learned location of interest into bigger groups based on location information of the learned location of interest using a pre-defined criteria.
US11333509B2
An information processing system acquires positional information of a vehicle, acquires positional information of a terminal device, estimates current transportation means of a user based on the positional information of the terminal device, decides information relating to a first route, along which the user moves to the vehicle, based on the positional information of the terminal device, the estimated current transportation means of the user, and the positional information of the vehicle, decides information relating to a second route, along which the user who has moved to the vehicle moves to a destination using the vehicle, based on a first predicted arrival time, the positional information of the vehicle, and positional information of the destination, and outputs first guide information for prompting the user to start moving along the first route in a form of a video or a sound.
US11333507B2
Aspects of the disclosure provide systems and methods for providing suggested locations for pick up and destination locations. Pick up locations may include locations where an autonomous vehicle can pick up a passenger, while destination locations may include locations where the vehicle can wait for an additional passenger, stop and wait for a passenger to perform some task and return to the vehicle, or for the vehicle to drop off a passenger. As such, a request for a vehicle may be received from a client computing device. The request may identify a first location. A set of one or more suggested locations may be selected by comparing the predetermined locations to the first location. The set may be provided to the client computing device.
US11333505B2
A system, a method, and a computer program product for generating updated map data are provided. The method comprises obtaining map data of a speed sign associated with a plurality of parallel roads, determining one or more effective links associated with the speed sign, based on the map data of the speed sign, determining first vehicle sensor data corresponding to the one or more effective links, and generating a speed index for each of the one or more effective links based on the first vehicle sensor data The method further comprises generating the updated map data based on the speed index for each of the one or more effective links.
US11333504B2
A method is described for updating a digital map for vehicle navigation. The method includes a step of determining an adjustment signal for adjusting a detection range of an environment sensor of a vehicle to a section of an environment of the vehicle that corresponds to an area of the digital map to be updated, using an item of information about the area to be updated, and the method including a step of supplying area data for updating the digital map, the area data representing an image of the section of the environment detected by the environment sensor.
US11333503B2
An autonomous vehicle (AV) includes a vehicle computing system including one or more processors programmed to receive map data associated with a map of a geographic location, determine, based on the map data, one or more local routes in the one or more roadways between the current location of the AV and one or more exit locations, and control travel of the AV based on a selected local route of the one or more local routes. The map includes one or more roadways in the geographic location. The map data includes a global route in the one or more roadways between a current location of the AV and a destination location of the AV. The one or more exit locations are located between the current location of the AV and the destination location of the AV.
US11333502B2
This disclosure describes a map-matching module that supports a Global Positioning System (GPS) and provides a user with a best match trajectory corresponding to GPS sampling points taken at a low sampling rate. The best match trajectory is based upon a spatial-temporal analysis.
US11333501B2
A navigation device may include a GNSS data editing part, an attitude angle calculating part, and a speed calculating part. The GNSS data editing part may generate GNSS attitude angle estimation data and GNSS speed estimation data by using first GNSS data based on a GNSS signal received by a first antenna, and second GNSS data obtained at a shorter cycle than the first GNSS data based on a GNSS signal received by a second antenna. The attitude angle calculating part may estimate an integrated attitude angle based on the IMU angular velocity outputted from an Inertial Measurement Unit (IMU) and the GNSS attitude angle estimation data. The speed calculating part may estimate an integrated speed based on an IMU acceleration outputted from the IMU, the GNSS speed estimation data, and the integrated attitude angle.
US11333496B2
A surveying instrument comprises a monopod installed on a reference point, a surveying instrument main body provided at a known distance from a lower end of the monopod and at a known angle with respect to an axis of the monopod and having a reference optical axis, wherein the surveying instrument main body performs an image pickup of an object to be measured and scans the object to be measured by a closed loop scan pattern respectively at a pre-rotation and a post-rotation of the surveying instrument main body, obtains cross points of a locus of a scan pattern of the pre-rotation and the post-rotation, obtains deflection angles of the cross point with respect to the reference optical axis of the pre-rotation and the post-rotation, and calculates a rotation angle of the surveying instrument main body based on a deviation between both of the deflection angles.
US11333493B2
An overload recognition system for a bar-type chassis component, having a sensor system which detects a nominal condition parameter of the chassis component. The sensor system is designed as a deformation detecting sensor system for an individual chassis component.
US11333489B2
An imaging device includes a pixel. The pixel includes: a first electrode; a second electrode facing the first electrode; a photoelectric conversion layer between the first electrode and the second electrode, the photoelectric conversion layer converting light into signal charge; and a charge accumulation region coupled to the second electrode, the charge accumulation region accumulating the signal charge. The pixel captures first data in a first exposure period and captures second data in a second exposure period different from the first exposure period, the first exposure period and the second exposure period being included in a frame period. A length of the first exposure period is different from a length of the second exposure period. The imaging device generates multiple-exposure image data including at least the first data and the second data.
US11333485B2
An alignment method for a beam-directing unit of an interferometric measuring device for directing a laser beam of a laser beam source towards a plurality of measurement points of an object under measurement, wherein a three-dimensional model of a measurement surface of an object under measurement is created by a plurality of spatially resolved images. A measuring device for carrying out an interferometric measurement by laser radiation is also provided, having a controller which is designed to align a beam-directing unit of the measurement device.
US11333477B2
A tape measure device and attachment for measuring and cutting drywall that includes a tape measure with an anchoring member disposed at the rear end of the housing and having a rear surface defining a rear aperture and a rear plane thereon and an upper surface opposing the rear surface of the anchoring member, with an anchor placement member coupled to the anchoring member, having a distal end, and operably configured to have an anchoring position with the distal end displaced a length outwardly away from the rear surface of the anchoring member, and being operably configured to have a first position along an anchoring member translation path with the rear plane non-co-planar with the bottom plane and a second position along the anchoring member translation path with the rear plane co-planar with the bottom plane.
US11333466B2
A means is provided for defending a target from attack by a torpedo with high probability. When a controller detects a torpedo based on an image generated by a sonar, it specifies a path of movement of the torpedo. If there is a water craft or the like within the path of movement, the controller instructs a launcher to launch a torpedo capture device and instructs mines to switch to detonation-off mode. Moveable devices of the torpedo capture device launched by the launcher in accordance with the instruction of the controller move in the water to spread a net. The controller then specifies a location of each of a first moveable device and second moveable devices based on an image generated by the sonar, and instructs the first moveable Device and the second moveable devices to move such that the center of the net is within the path of movement of the torpedo. The first moveable device and the second moveable devices move in accordance with the instruction of the controller. When the torpedo reaches the net, the net captures the torpedo and the mines, which are in the detonation-on mode, explode the torpedo before it reaches the water craft or the like.
US11333458B1
An underwater muzzle suppressor system for directing away from a user the blast pressure of a firearm has an interior cylinder with a rearward end and a forward end with primary axial slots formed in the interior cylinder adjacent to the rearward end. An exterior cylinder has a rearward end and a forward end with secondary axial slots formed in the exterior cylinder adjacent to the forward end. A cylindrical chamber is created between the interior cylinder and the exterior cylinder. A rearward disk is received over the rearward end of the interior cylinder. The rearward disk is coupled to the rearward end of the exterior cylinder. A forward disk receives the forward end of the interior cylinder. The forward disk is coupled to the forward end of the exterior cylinder. A plurality of axial holes are in the forward disk.
US11333454B2
The present invention relates to the field of military technology, and more particularly to an automatic firearm. Said firearm consists of a receiver, a barrel, a bolt carrier and a bolt, a bumper spring on the bolt carrier, a recoil spring between the bolt carrier and the rear wall of the receiver, a trigger mechanism, an ammunition feed mechanism, sighting equipment, a device for locking the bumper spring in a compressed state caused by the bolt carrier striking the front wall of the receiver or the barrel or the bolt via the bumper spring, and a mechanism for synchronizing the release of the bumper spring with the firing of a shot. Additionally, the firearm can be provided with an additional bumper spring between the bolt carrier and the rear wall of the receiver, and a lever for compressing and subsequently releasing said additional bumper spring in case the manual reloading in order to impart additional kinetic energy to the bolt carrier for the forward movement thereof, wherein said lever can be combined with a recharging handle. Additionally, the firearm can be provided with an additional device for locking the bumper spring in a compressed state caused by the bolt carrier striking the rear wall of the receiver via the bumper spring, and a lever for compressing and subsequently locking the bumper spring during the rearward movement of the bolt carrier in the case of manual reloading, wherein said lever can be combined with a recharging handle. The technical result provided by the above combination of features is the creation of a firearm having an inertial automatic loading system that functions reliably and consistently due to the increased reloading system working speeds and increased recovery of recoil energy.
US11333432B2
A refrigerator includes a cabinet defining a storage chamber, a drawer door inserted into and withdrawn out of the storage chamber, a motor assembly provided at the storage chamber, a rack gear assembly provided at the drawer door and having an extendable rack gear that is configured to be coupled to the pinion gear, and a guide unit that is provided at an inner surface of the storage chamber and configured, based on the drawer door being withdrawn out of the storage chamber, to couple a portion of the rack gear assembly to the inner surface of the storage chamber to thereby allow the rack gear to extend. The drawer door includes a drawer part that defines an upwardly open storage space, and a door part that is configured to, based on the drawer door being inserted into the storage chamber, close the storage chamber.
US11333428B2
The invention is provided with a housing which has an inner space open in a first direction, a partition body which divides the inlet of the inner space into a plurality of openings arranged next to each other in a second direction perpendicular to the first direction, a door which is provided to each of the openings and which closes the opening from the first direction side, a first vacuum heat insulating material which is disposed inside the partition body, and a second vacuum heat insulating material which is disposed inside the door. The first vacuum heat insulating material and the second vacuum heat insulating material are arranged so as to overlap each other when viewed from the first direction side or from the second direction side.
US11333425B2
A freezer cabinet (10) for storing frozen confectionery products, the freezer cabinet comprising: a chamber having an opening substantially sealed by an upper surface panel (18, 20); and a further panel (22, 24) inside the chamber being spaced away from the upper surface panel and substantially parallel to the upper surface panel in at least one direction and creating a quiescent region between the upper surface panel and further panel wherein the quiescent region is in gaseous communication with the air in the chamber. The upper surface panel comprises at least one slideably openable section (18, 20); the further panel comprises at least one slideably openable section (22, 24); and the chamber comprises a side wall (12, 14) and a coolant evaporator (40) mounted in and/or on the side wall. The height distance (H) between the further panel, measured from the lowest face of the further panel facing the chamber, and the highest part of the evaporator is at least 5 mm.
US11333424B2
A refrigerator includes an evaporator arranged in a heat exchange chamber and having refrigerant pipes through which refrigerant flows and fins configured to guide heat exchange between the refrigerant and cold air, wherein the evaporator includes a first and a second side spaced apart from each other, and the fins of the evaporator guide flow of air such that the cold air introduce into the first and second sides is combined with each other in the space between the first and second sides.
US11333423B2
Arrangement for accumulation and evacuation of water such as defrosting and condensation water from refrigeration units, the system including a piping arrangement with a vertical pipe section extending from a water evacuation unit provided in conjunction with the respective refrigeration unit; discharge valves, one for each unit; one or more liquid reservoir for each unit; one or more vacuum pumps; air inlet nozzles; a control unit; one or more level switches and air conduit inlet opening for each vertical pipe. Each of the water evacuation units includes a docking station and a water collection tray preferably to be slideably provided within the docking station, whereby each unit is custom made to fit between the refrigeration unit and floor where the refrigeration units are placed.
US11333413B2
A solid state cooler device is provided that includes a substrate, a first and second conductive pad disposed on the substrate, a first and second superconductor pad each having a side with a plurality of conductive pad contact interfaces spaced apart from one another and being in contact with a surface of respective first and second conductive pads, and a first and second insulating layer disposed between respective first and second superconductor pads, and respective ends of a normal metal layer. A bias voltage is applied between one of a first conductive pad or first superconductor pad and one of the second conductive pad or the second superconductor pad to remove hot electrons from the normal metal layer, and the contact area of the plurality of first and second conductive pad contact interfaces inhibits the transfer of heat back to the first and second superconductor pads.
US11333407B2
A GM cryocooler includes a compressor having a compressor discharge port and a compressor suction port, a displacer capable of reciprocating in an axial direction, a displacer cylinder accommodating the displacer, a drive piston connected to the displacer so as to drive the displacer in the axial direction, a drive chamber in which the drive piston is driven, a main pressure switching valve configured to alternately connect the displacer cylinder to the compressor discharge port and the compressor suction port, an auxiliary pressure switching valve configured to alternately connect the drive chamber to the compressor discharge port and the compressor suction port, and a buffer volume connected between the auxiliary pressure switching valve and the compressor.
US11333402B1
A thermal management system is described. The thermal management system includes an open circuit refrigeration circuit that has a refrigerant fluid flow path, with the refrigerant fluid flow path including a receiver configured to store a refrigerant fluid, an ejector having a primary flow inlet configured to receive refrigerant, a liquid separator, an evaporator configured to extract heat from a heat load that contacts the evaporator, with the evaporator coupled to the ejector and the liquid separator, and an exhaust line coupled to a vapor side outlet of the liquid separator. In operation, the evaporator in the open circuit refrigeration circuit would be coupled to a heat load.
US11333400B2
The present invention provides a hot water storage-type boiler having both a heat amount proportional control function and a backflow prevention function to prevent a backflow of exhaust gas with a simple structure. In the present invention, since a check valve is integrally coupled to a burner duct, there is an effect of convenient assembly. In addition, since the check valve is built in the burner duct, the check valve does not protrude to the outside, thereby having an effect that a separate space is not required.
US11333395B2
A system for managing drainage of heat pump coil condensate using a building's legacy heat piping infrastructure. The system includes a drainage pan that accumulates condensate and directs it into condensate piping. The condensate piping feeds the condensate into the building's legacy heat piping infrastructure, preferably after treating the condensate with a neutralizer to reduce its acidity. The system also includes a system control for monitoring the accumulated condensate levels and the status of the legacy heating system to determine when to open a flow control means allowing the condensate to drain from the condensate piping into the building's legacy heat piping infrastructure.
US11333393B2
A condensation management system includes an elongated flexible film configured to be stretched under tension between a first film support and a second film support. The film includes first and second ends that extend laterally across a width of the film. The film includes first and second sides that extend longitudinally between the first and second film ends. The film has a concave surface and an opposing convex surface extending between the first and second sides of the film. Microchannels are disposed in at least one of the concave surface and the convex surface. The microchannels induce a predetermined radius of curvature in the concave and convex surfaces of the film when the film is stretched longitudinally between the first and second film supports.
US11333388B2
When a state in which a driving voltage of a pump is set to an upper limit voltage and an opening degree of at least one of a plurality of flow rate control valves is set to a maximum opening degree continues for a first determination time period, an operation frequency of a compressor is raised at a first time so as to increase an amount of heat exchange by a second heat exchanger. When an operation stop request is input, or an indoor temperature reaches a set temperature, in at least one of a plurality of third heat exchangers after the first time, the operation frequency of the compressor is lowered or the driving voltage of the pump is lowered.
US11333377B2
A humidifier includes a base housing having a receiving cavity and an air outlet, a water tank having a vapor outlet, a vaporizing arrangement having a vaporizer and a fan, and a waterproof arrangement. The waterproof arrangement includes a blocking member movably mounted on the base housing to selectively move between an opened position and a closed position, wherein when the water tank is detached from the base housing, the blocking member is driven to block the air outlet so as to prevent water from passing through the air outlet, wherein when the water tank is attached on the base housing, the blocking member is driven to unblock the air outlet so as to allow air created by the fan to flow through the air outlet.
US11333371B1
A dedicated outdoor air system and method that is capable of operating over a broader spectrum of conditions. The HVAC system of the present invention utilizes a heating means positioned within the return air passageway in order to optimize the regeneration of the desiccant wheel and energy recovery device. By positioning a heating means upstream of the regeneration side of the desiccant wheel, the system is capable of providing supply air having low dew points to the enclosed space while still providing improved energy efficiency over conventional HVAC systems.
US11333356B2
An edge-banding apparatus is provided and configured to apply an edging strip having a heat activated layer to a substrate or work piece. The apparatus uses localized heat generated from a controlled flame from combustible fuel to apply heat to the edging strip to active the heat activated layer.
US11333354B2
A waste treatment unit. It comprises at least one gasifier having a main receptacle (1) with a waste inlet (2), a syngas outlet (6) and an ashtray outlet (8). In the interior of the receptacle there is a body (4) with at least one inclined section (7) disposed opposite to the waste inlet (2), and with a base (14) which creates a depletion shaft (17) that prevents the passage of waste; and a dividing wall (9a) in contact with said body (4) or an evacuation tube (9a) in the interior of the body (4), such as to create a waste zone (15) that encompasses at least the zone where the inclined section (7) is located, and a waste-free zone (16) wherethrough the syngas produced during oxidation of the waste flows towards the syngas outlet (6).
US11333353B2
The object of the present invention is to provide a burner which is capable of decreasing the amount of NOx emission and heating the object to be heated uniformly with excellent heat transfer efficiency when heating the object to be heated while oscillating the flame by self-induced oscillation, and a method for heating using a burner, and the present invention provides a burner including a center fluid ejection outlet 2 having a sectional fan shape in which an interval between a pair of side walls 63a and 63b gradually expands toward a downstream side, a pair of openings 62a and 62b provided on side walls 61 of a fluid ejection flow path 6 on an upstream side of the central fluid ejection port 2 and communicated by a communication pipe 7, a first peripheral fluid ejection outlet arranged around the center fluid ejection outlet, a second peripheral fluid ejection outlet is arranged at a position at which a distance between a center thereof and a center of the center fluid ejection outlet is larger than a distance between a center of the first peripheral fluid ejection outlet and the center of the center fluid ejection outlet, and in a direction orthogonal to an expanding direction of the center fluid ejection outlet, and a third peripheral fluid ejection outlet is arranged at a position at which a distance between a center thereof and the center of the center fluid ejection outlet is larger than the distance between the center of the second peripheral fluid ejection outlet and the center of the center fluid ejection outlet, and in the direction orthogonal to the expanding direction of the center fluid ejection outlet.
US11333351B2
The present invention is intended to prevent lifetime degradation of a conductor tube by reducing heat deterioration at output ports of the conductor tube. A superheated steam generator generates superheated steam by heating steam flowing through a spirally wound cylindrical conductor tube. The conductor tube is axially short-circuited and subjected to induction heating by a magnetic flux generation mechanism disposed on one or both of inner and outer sides of the conductor tube. Output ports of the conductor tube are disposed at axial midportions of the conductor tube.
US11333349B2
Disclosed herein are a fluid sand falling type circulating fluidized bed boiler with a plurality of risers for preventing erosion and corrosion of water tubes and increasing combustion efficiency, and a method of operating the same. The fluid sand falling type circulating fluidized bed boiler with a plurality of risers includes a boiler section into which fuel and oxidizer are injected, a riser section connected to the boiler section so that the fuel and fluid sand supplied from the boiler section are introduced from the bottom of the riser section and flow up, and a relay section provided on the boiler section to supply the fluid sand having passed through the riser section to the boiler section, wherein the fuel is injected from the top of the boiler section and burned while flowing down therein.
US11333347B2
An illumination device includes a first light-emitting module, a second light-emitting module and an airflow-guiding structure. The second light-emitting module is adjacent to the first light-emitting module. The airflow-guiding structure includes a receiving casing, a first air inlet pipe in air communication with the receiving casing, and a first air outlet pipe in air communication with the receiving casing. The first light-emitting module is received inside the airflow-guiding structure. When external air flows into the receiving casing through the first air inlet pipe by natural convection, the external air inside the receiving casing is sterilized by a sterilization light source provided by the first light-emitting module, and the external air that has been sterilized by the sterilization light source flows out of the receiving casing through the first air outlet pipe by natural convection, and is then discharged out of the illumination device.
US11333344B1
A multifunctional lamp includes a lighting device and a sterilization device. The lighting device includes a base, a lighting member configured to emit flame-like light; and a light-transmitting suspending chamber defined with a mounting opening. The lighting member is mounted into the light-transmitting suspending chamber through the mounting opening. The light-transmitting suspending chamber is arranged at one side of the base with the base sealing the mounting opening and the sterilization device is arranged at the other side of the base. When the multifunctional lamp is put into liquid, the light-transmitting suspending chamber is capable of floating on the liquid and the sterilization device is capable of being deep into the liquid to sterilize the liquid.
US11333343B2
A lighting device (e.g., a controllable light-emitting diode illumination device) may have a light-generation module that may be assembled and calibrated prior to the light-generation module being installed in a finished good. The light-generation module may include an emitter module having at least one emitter mounted to a substrate and configured to emit light. The light-generation module may include a first printed circuit board on which the emitter module may be mounted and a second printed circuit board on which those circuits that are essential for powering the emitter module may be mounted. The light-generation module may include a heat sink located between the first printed circuit board and the second printed circuit board. The emitter module may be thermally-coupled to the heat sink through the substrate and the first printed circuit board.
US11333340B1
A touch controller for an LED light string or light strip is disclosed. The touch controller includes a housing, an end cover connected with the housing, a liquid-sealed accommodating cavity being defined between the end cover and the housing, a printed circuit board positioned in the accommodating cavity, a light-emitting control circuit being arranged on the printed circuit board, a touch input unit positioned in the accommodating cavity, the touch input unit being electrically connected with the light-emitting control circuit, one part of the touch input unit being matched with the housing or the end cover, and when a touch behavior is applied to the part, matched with the touch input unit, of the housing or the end cover, a trigger signal is provided for the light-emitting control circuit through the touch input unit.
US11333338B2
Lighting device, in particular for automotive lighting applications, comprising a plurality of lighting elements arranged in one or more rows in order to form a luminous band, wherein each lighting element comprises at least one or more light emitting diodes (LEDs). The plurality of lighting elements is divided into one or more segments, wherein the lighting elements within each segment are electrically connected in series or in parallel. The lighting device further comprises at least one contacting element providing current for the plurality of lighting elements, wherein at least a first contacting element provides current for a first group of segments such that groups of lighting elements are independently and dynamically controlled.
US11333334B2
Methods and apparatus for a rotatable light fixture secured to a junction box via a mounting base. The electrical and/or mechanical connection between the light fixture housing and the mounting base may maintain the electrical coupling during rotation. The light fixture housing may be rotationally secured in a variety of rotational orientations relative to the mounting base.
US11333333B1
An outdoor solar ground light includes a primary light board and a plurality of secondary light boards installed in the outdoor solar ground light and electrically connected with each other without requiring the use of a conductive wire, and capable of emitting light around the top and the sides of the ground light simultaneously, and the ground light adopts a light emitting diode such as a white/warm white LED or a RGB LED provided for users to select their favorite color or change the color cyclically. Unlike the commercial available ground light, the present invention has the advantages of simple assembling, easy use, convenient transportation and packaging, and aesthetic merchandise appearance.
US11333330B2
The invention provides a metal-based support (100) for a lighting element (200), wherein the lighting element (200) comprises a light source support (300) and a light source (10) functionally coupled to the light source support (300), wherein the metal-based support (100) comprises a metal body (140) and a fixation element (400) for fixating the light source support (300) to the metal-based support (100), wherein at least part of the fixation element (400) is part of the metal body (140), wherein the fixation element (400) comprises a central part (410) which is configurable in a first configuration and in a second configuration, different from the first configuration, wherein a change from one configuration to the other can be effected by applying a force on the central part (410), wherein the fixation element (400) comprises two protruding elements (420) configured extending from the central part (410) in both configurations of the central part (410), wherein terminal parts (421) of the respective protruding elements (420) have a first mutual distance (d1) in the first configuration of the central part (410) and a second mutual distance (d2) in the second configuration of the central part (410), wherein the first mutual distance (d1) is larger than the second mutual distance (d2), and wherein the fixation element (400) is configured to receive the light source support (300) in the first configuration and to fixate the light source support (300) to the metal-based support (100) in the second configuration.
US11333324B1
The present application relates to the technical field of films and television lighting, and provides a lamp and an optical lens thereof, the lamp includes: a lamp body, a first housing and a second housing, the first housing is provided with slots, the second housing is movably sleeved inside the first housing, and an outer wall of the second housing is provided with a protruding member extending through the slots, the protruding member further simultaneously moves relative to the second housing while moves in the slot, to adjust a distance between the second housing and the lamp body. When the protruding member moves in the slot on the first housing, a part of the protruding member can also move relative to the second housing at the same time.
US11333320B2
A method and apparatus for improving the optical properties of an LED using a retroreflector element. A light emitting apparatus includes a substrate, at least one light emitting device attached to the substrate and including an outer primary light emitting surface through which substantially all light is emitted, and a retroreflector assembly attached to the substrate. The retroreflector assembly includes a proximal surface adjacent to the substrate, a distal surface spaced away from the substrate, and a retroreflective portion arranged between proximal surface and the distal surface. A distance from the distal surface to the substrate is less than or equal to a distance from the outer primary light emitting surface to the substrate.
US11333319B2
An illuminating module includes a light source assembly which includes a first lens unit. The light source assembly is configured to produce an illuminating beam, wherein the optical apparatus includes an optical modulation module and a light guiding module, the optical modulation module is parallel corresponding to the first lens unit, the illuminating beam passes through the optical modulation module to be an image beam having an image, and the image beam travels in the light guiding module, and leaves the light guiding module. The illuminating beam obliquely enters the optical modulation module.
US11333313B2
A vehicle lamp module and a vehicle using same. The vehicle lamp module comprises: a low beam circuit board (1), a low beam reflector (2), a high beam circuit board (3), a high beam condenser (4), a heat radiator (5), a lens (6), a lens support (7), and a module support (8), wherein the low beam reflector (2) serves as an optical element for forming a low beam shape, and the high beam condenser (4) serves as an optical element for forming a high beam shape. The vehicle lamp module has a good light shape uniformity, good low beam visibility, good high beam lighting performance, and excellent heat dissipation performance. Moreover, the module has a relative simple structure, a light weight, a small volume, a low cost, and a good comprehensive performance.
US11333302B2
Described are storage and dispensing vessels and related systems and methods, for dispensing reagent gas from a vessel in which the reagent gas is held in sorptive relationship to a solid adsorbent medium, the reagent gas being contained at super-atmospheric pressure and the solid adsorbent medium comprising a metal-organic framework.
US11333300B2
A high pressure tank is provided. The high pressure tank provides improved strength and stiffness by optimizing a laminating pattern and a structure of a fiber reinforced plastic that forms a dome portion of the high pressure tank used in a fuel tank of a fuel cell vehicle. The fiber reinforced plastic having relatively high strength is mixed and used for a weak portion of a dome portion of a support layer of a high pressure tank where stress caused by internal pressure of the high pressure tank is concentrated. In particular, bursting strength and stiffness is increased. The usage amount of the fiber reinforced plastic, the number of windings and a thickness by directly reinforcing a weak point of the dome portion are reduced. Accordingly, manufacturing costs of the high pressure tank are reduced.
US11333296B2
A display panel frame is provided. The frame includes a substrate having a bendable portion and two connecting portions connected to two sides of the bendable portion; and a connecting structure including two connecting members and an elastic belt. The two connecting members are respectively mounted to the two connecting portions and disposed opposite to each other, and the elastic belt is sleeved on the two connecting members and wound around outer surfaces of the two connecting members. Thus, the structural design of the product can be simplified to ensure that it does not cause product failure after bending over a long period of time, and increase the toughness of the flexible substrate, so that it is beneficial to ensure product reliability under long time bending.
US11333293B2
A mount system for a monitoring device is disclosed. The mount system may include an extension arm attached to a device structure for housing the monitoring device. The mount system may include an alignment cup coupled to a support structure, wherein the extension arm is received through a through hole in a base of the alignment cup, and an oblong fitting attached to the extension arm opposite the device structure, wherein the oblong fitting is complementarily shaped to be received within the alignment cup to be received within the alignment cup, such that when the oblong fitting is received within the alignment cup, the device structure is aligned into a monitoring location. The mount system may include a dampening component between the support structure and the extension arm to bias the device structure into the monitoring location.
US11333290B2
A hollow-cylindrical heat shield includes at least one graphite foil and at least one fiber structure, preferably a wound fiber structure, disposed on the outer side of the at least one graphite foil. The (wound) fiber structure has a degree of coverage of less than 100%. A high-temperature furnace or gas converter having a heat shield is also provided.
US11333288B2
A production method for an aerogel laminate includes a step of preparing a sol of producing a sol for forming an aerogel, an applying step of applying the sol obtained in the step of preparing a sol to a support having a heat ray reflective function or a heat ray absorbing function, and drying the sol to form an aerogel layer, an aging step of aging the aerogel layer obtained in the applying step, a washing step of washing the aged aerogel layer and performing solvent exchange, and a drying step of drying the aerogel layer washed in the washing step.
US11333285B2
A hose coupling guard including a fixture configured to connect to a hose coupling having a release mechanism, and a cover movably connected to the fixture to be movable between a first position and a second position. The cover includes a shield configured to enclose the release mechanism when the cover is in the first position, and to expose the release mechanism when the cover is in the second position. A display surface may be located on the shield and configured to be oriented to face a location from which an operator can operate the release mechanism.
US11333284B2
The invention relates to an assembly for centring a first elongate tubular element and a second elongate tubular element, such as an underwater pile accommodated within a noise mitigation screen, at a common central longitudinal axis along which axis both the first and second element extend, and wherein the centre system is provided with first coupling element for fixedly coupling the centre system with one of the first and second tubular elements, and second coupling element for engaging the other tubular element for centring the other tubular element at the central axis.
US11333278B2
A pipe-joining centering device aligns, with an axial center of one pipe, an axial center of another pipe when a spigot of the other pipe is to be inserted into a socket of the one pipe. The pipe-joining centering device includes a support member configured to support an end part of the spigot. The support member is tiltable in a pipe radial direction between an inner peripheral surface of the socket and an outer peripheral surface of the spigot. The pipe-joining centering device also includes a position adjustment member configured to tilt the support member in the pipe radial direction. The support member and the position adjustment member are supported on the inner peripheral surface of the socket.
US11333276B2
A clamp element, in particular a band clamp, has a first end portion and a second end portion which are arranged at a distance with respect to one another. A first element engages on the first end portion and a second element engages on the second end portion. The elements are or can be brought into engagement with one another by an engagement portion, and the engagement portion is formed between the end portions.
US11333274B2
A hose connector assembly for connecting a hose to a port of a pressurized fluid system, the system including a socket and an adapter tube in fluid communication, with an end portion of the socket adapted to be connected to a port and having a receiving opening. The adapter tube has a plug-in end portion to be pushed into the receiving opening which is adapted to cooperate with the plug-in end portion to form a plug-in connection mechanism. The adapter tube has a hose connector end fitting adapted to be received in, hold and retain a hose end portion. Complementary locking surfaces of the receiving opening and plug-in end portion are engaged when the plug-in end portion is connected by the plug-in connection mechanism to the socket to lock the adapter tube with respect to the socket against rotation about the longitudinal axis of the adapter tube within the socket.
US11333273B2
A hybrid fluid-flow assembly having a base fitting that has been formed by axial load bulge forming from a sheet of metal, and a custom fitting that has been machined from a shaped-memory alloy. At least one connection port of the custom fitting is connected to at least one connection port of the base fitting by an interference fit. The interference fit is formed by cooling the custom fitting to a temperature below its transition temperature, deforming the custom fitting so that the diameter of its connection port is slightly larger than the connection port on the base fitting, installing the connection port of the custom fitting on the connection port of the base fitting, and allowing the custom fitting to warm to room temperature. The shaped-memory alloy swages and coins the outer surface of the base fitting at the interface of the ports, thereby forming a compressive, interference fit.
US11333268B2
Disclosed is a deterioration determination device for a liquid pumping apparatus including: a casing that forms a reservoir space for storing liquid flowed thereto; a feed valve that introduces working gas into the reservoir space; an exhaust valve that releases the working gas from the reservoir space; and a valve operating mechanism having a float arranged in the reservoir space, and performing a pumping stroke in which the liquid is pumped from the reservoir space under a pressure of the working gas by opening the feed valve and closing the exhaust valve when the float moves up to a predetermined high level, and an inflow stroke in which the liquid flows into the reservoir space and the working gas is released from the reservoir space by closing the feed valve and opening the exhaust valve when the float moves down to a predetermined low level. The deterioration determination device includes a first pressure sensor arranged to communicate with a lower portion of the reservoir space to detect a pressure of a liquid layer in the reservoir space, and a deterioration determination unit that determines a degree of deterioration of the valve operating mechanism based on a change in the pressure detected by the first pressure sensor.
US11333267B2
A valve for pressurized fluid including a body having a front face and a rear face and housing an internal fluid circuit having an upstream end configured to be placed in communication with a reserve of pressurized fluid and a downstream end configured to be placed in communication with a user of fluid, the circuit including a collection of valve shutter(s) including at least one shutoff valve shutter allowing the circuit to be closed or opened, the valve including a control lever controlling the collection of valve shutter(s), an end for grasping, the control lever being mounted with the ability to rotate on the valve between a rest position and an active position in which the control lever is away from the body of the valve and actuates the collection of valve shutter(s) into a position in which the circuit is open with a first bore section.
US11333259B2
A rotary valve system includes a first body having a first plurality of fluid channels. The first fluid channels have a common first inlet to receive a fluid and a first outlet. The system includes a second body coupled to the first body. The second body has a second plurality of fluid channels. The second fluid channels have a second inlet and a second outlet. The system includes a plate assembly having a plate coupled between the first body and the second body. The plate is movable between at least a first, open position in which the first outlet of at least one of the first fluid channels is in fluid communication with the second inlet of at least one of the second fluid channels and a second, closed position in which the second inlet of each of the second fluid channels is substantially completely obstructed by the plate.
US11333253B2
A magnetic seal assembly comprises a metallic annular wear seal. A magnetic seal has a magnetic annular body adjacent to and attracting the wear seal into contact against a contact face thereof. A retainer ring is connected to a surface to the magnetic seal, the retainer ring having a coefficient of thermal expansion different than a coefficient of thermal expansion of the annular body, the coefficient of thermal expansion of the retainer ring selected to constrain a thermal expansion of the annular body. A method for controlling a thermal expansion of a magnetic seal assembly is also provided.
US11333250B2
A seal ring capable of stabilizing sealing performance while reducing rotation torque. A seal ring 100 has a plurality of first dynamic pressure generation groove 131 and a plurality of second dynamic pressure generation groove 132 on an outer peripheral surface thereof with intervals in the circumferential direction, the plurality of first dynamic pressure generation groove 131 extending from a position close to a first side surface 100A with respect to the center of width in an axial direction to the first side surface 100A and configured to generate dynamic pressure with relative rotation between a housing and the seal ring 100, and the plurality of second dynamic pressure generation groove 132 extending from a position close to a second side surface 100B with respect to the center of width in the axial direction to the second side surface 100B and configured to generate dynamic pressure with the relative rotation between the housing and the seal ring 100.
US11333247B2
A metal gasket includes: a straight section provided with a bolt hole; a bead section raised from an inner peripheral edge of the straight section toward one side of the direction of the thickness of the gasket; and a bent section bent from an outer peripheral edge of the straight section toward the other side of the direction of the thickness of the gasket. When metal gasket is compressively sandwiched by a pair of housings, bead section elastically deforms to decrease height, and straight section elastically deforms, whereby the inner peripheral edge of the straight section contacts one of the housings, the outer peripheral edge of the straight section contacts the other housing, and the bent section contacts the one of the housings. A gasket installation determination projection is part of the periphery and provided on the outer peripheral edge of the bent section or of the straight section.
US11333245B2
An oil control ring according the present disclosure includes a pair of side rails, and a spacer expander disposed between the pair of side rails. The spacer expander includes a plurality of sets and each set includes a lug part and a rail facing part. For each set, the lug part is in contact with an inner circumferential surface of either of the pair of the side rails, and the rail facing part is provided adjacent to the lug part and faces a side surface of either of the pair of the side rails. The lug part satisfies a following condition (1): W/H≥1.5 (1) In condition (1), W indicates a width of the lug part at a position 0.05 mm away from a highest position of the lug part in a direction towards the rail facing part, and H indicates a height difference between a highest position of a region on the rail facing part adjacent to the lug part and the highest position of the lug part.
US11333238B2
A drive apparatus includes a motor; a reduction gear connected to the motor; a differential connected to the reduction gear, for rotating an axle about a differential axis; a housing including a gear housing portion housing the reduction gear and the differential; and an oil housed in the gear housing portion. The differential includes a gear for rotating about the differential axis. An end portion of the gear is lower than the reduction gear, and is configured to soak in the oil. The housing includes an oil drain hole and an oil feed hole for joining an interior of the housing and a space outside of the housing, a first stopper member removably in the oil drain hole, and a second stopper member removably in the oil feed hole. Each of the oil drain hole and the oil feed hole is in a portion of the gear housing portion.
US11333236B2
A drivetrain system including an axle assembly that may have an electric motor module, a gear reduction module, a drive pinion, a differential assembly, an auxiliary shaft, and a shift collar. The shift collar may selectively couple the auxiliary shaft, the drive pinion, and the gear reduction module in various combinations.
US11333235B2
A hybrid drive component, such as a pulley, a drive sprocket, or an idler is composed of metal and composite material. The drive component manufacturing methods extend the overall life of the pulley while also reducing material usage and product weight thereby making the application more efficient. The drive component includes a drive element, a hub/bearing element and a connecting element. The connecting element is a molded construction that interconnects the drive element and the hub element.
US11333231B2
A drive control apparatus includes a circuitry configured to operate a differential lock device of a differential device in timings which are different between a two wheel drive state and a four wheel drive state. The differential device is disposed between one of a pair of front wheels and a pair of rear wheels of the vehicle and configured to transmit a driving force from a drive source to the one of the pair of front wheels and the pair of rear wheels. The differential lock device is configured to lock a differential rotation of a pair of output members of the differential device that are differentially rotatable with respect to each other, and configured to respectively output the drive force.
US11333217B2
A drive assembly for a vehicle drive train includes a base assembly including a base hub configured for non-rotatably connecting to an outer circumferential surface of a transmission input shaft. The base assembly includes a torsional damper fixed to the base hub. The torsional damper includes an input section and an output section drivingly connected by springs. The springs allow relative rotation between the input section and the output section. The output section of the torsional damper is non-rotatably fixed to the base hub. A hub assembly extension is configured for non-rotatably connecting to an engine crankshaft. The hub assembly extension is non-rotatably fixed to the input part of the torsional damper at an engine side of the torsional damper. The torsional damper allows relative rotation between the hub assembly extension and the base hub.
US11333216B2
A connector including: a first buffer member that includes a spiral-shaped wire in a plan view; a second buffer member that has a substantially annular and flat plate-like shape, and that is capable of warping in a thickness direction; a collar member that includes a cylindrical portion surrounded by the first buffer member and the second buffer member, a first flange facing a radially inner side of the first buffer member, and a second flange facing a radially inner side of the second buffer member; and a coupling member that includes a first holder section holding radially outer sides of the first buffer member and the second buffer member, a second holder section holding the shielding body, and a coupling member base portion.
US11333206B2
The actuator (20) comprises an electric drive means (22) and a drive member (26) being rotationally driven upon activation of the electric drive means (22), an output member (24) being rotationally connected to the drive member (26) by means of a first spring (28), and a second spring (32) being connected to the output member (24) and forming a one way clutch between the output member (24) and a fixed tube (34), wherein the electrical actuator (20) further comprises a regulation cup (30) being configured to engage with the second spring (32) to disconnect the output member (24) from the fixed tube (34).
US11333199B2
An assembly comprising: a core in the form of a toroid; and at least one washer overlying the core, the washer comprising a polymer, wherein the washer has an arcuate cross-section so as to have a shape complementary to the core.
US11333191B2
A crankshaft includes a first oil hole, a second oil hole, and a through hole. The second oil hole extends in a direction in which the second oil hole intersects the first oil hole. A first extension is an imaginary line extending from an inner wall surface of the first oil hole on a second oil hole side. A second extension is an imaginary line extending from an inner wall surface of the second oil hole on a first oil hole side. The through hole passes through an intersection between the first extension and the second extension. At least one end of the through hole opens on an outer peripheral surface.
US11333184B2
A joining system for use in furniture and furnishing items with a bottom and a shoulder has a front actuation axis under the bottom and includes a front joining unit and a rear joining unit positioned between the bottom and the shoulder of the furniture or furnishing item. A connection group is inserted in each front and rear joining unit and is aligned with a symmetry axis of the bottom, and a blocking group of the front and rear joining units is attached beneath the thickness of the bottom. The front joining unit provides an actuation and supporting member toward the rear joining unit, and the blocking group provides a grub screw inserted in a casing and caused to slide by way of a conical rack and pinion system, to be received in a bevel in the pin.
US11333181B2
Example aspects of a stiffening system for a hanger assembly, a hanger assembly, and method of reinforcing a hanger assembly are disclosed. The stiffening system for a hanger assembly can comprise a stiffener rod; a brace member oriented parallel to the stiffener rod; a stiffening connector coupling the brace member to the stiffener rod, the stiffening connector defining a connector hook and a fastener hole, the connector hook defining a hook recess, a portion of the brace member received in the hook recess; and a connector fastener extending through the fastener hole, the connector fastener pressing the stiffener rod into a corner region defined between the brace member and the stiffening connector.
US11333179B2
A mounting device (10) is disclosed having a one-piece body (11). A slot (20) extends into this body (11), and is defined by a slot base (22) and a pair of spaced slot sidewalls (24a, 24b) that each extend from the slot base (22). The slot sidewalls (24a, 24b) are disposed in non-parallel relation to each other.
US11333175B2
The subject matter of this specification can be embodied in, among other things, a rotary actuator that includes a first rotary actuator assembly having a first housing, a first mounting assembly radially projecting from a first longitudinal end of the first housing and defining a first axial aperture, and a first output shaft extending into the first axial aperture, a second rotary actuator assembly having a second housing, a second mounting assembly radially projecting from a second longitudinal end of the second housing and defining a second axial aperture, and a second output shaft extending into the second axial aperture, and a bearing assembly having an outer surface in contact with at least one of the first mounting assembly and the second mounting assembly, and an inner surface in contact with at least one of the first rotor assembly and the second rotor assembly.
US11333172B1
The air moving device includes a rotor and a stator. The quantity of the rotor blades is not less than 5 and not greater than 12. The average blade angle of rotor blades is not less than 45 degrees and is not greater than 64 degrees. The ratio of the hub diameter to the rotor diameter is not less than 0.4 and not greater than 0.79. The quantity of the stator blades is not less than 6 and not greater than 23. The average blade angle of stator blades is not less than 45 degrees and not greater than 70 degrees. The ratio of the total thickness of the air moving device to the rotor diameter is not less than 0.76 and not greater than 1.7. The ratio of the stator axial thickness to the rotor axial thickness is not less than 0.28 and not greater than 0.65.
US11333170B2
A cooling system for optimizing fan air flow performance without compromising acoustic performance is disclosed. At least three fan feature embodiments are disclosed: (1) sloped fan blades, (2) sloped impeller hubs, and (3) inlet flow guidance features. For the first embodiment, fan blades attached to an impeller disc and having leading edges that progressively curve toward a center of the impeller disc. For the second embodiment, the impeller disc is attached to and centered on an impeller hub that has a sloped hub surface that progressively curves toward the fan blades. For the third embodiment, an inlet flow guidance feature is positioned within a region surrounding a fan's inlet promoting smooth passage of air into the fan. In some embodiments, all three fan features are combined.
US11333167B2
To provide a method of designing a blade of an axial flow fluid machine that has a blade surface whose radius of curvature is continuous at a leading edge thereof and has a high aerodynamic performance. The method includes a step of determining a pressure surface curve and a suction surface curve as curves capable of first to third order differentiations at respective connection points to a leading edge curve, that is, a pressure surface connection point and a suction surface connection point, and a step of forming the leading edge curve as a fifth order Bezier curve that is defined by a first control point, a second control point, a third control point, a fourth control point, a fifth control point and a sixth control point. The first control point is the suction surface connection point. The sixth control point is the pressure surface connection point. Provided that an intersection of a tangent to the pressure surface curve at the pressure surface connection point and a tangent to the suction surface curve at the suction surface connection point is referred to as a point ahead of the blade, the second and fifth control points are points that internally divide line segments connecting the point ahead of the blade to the suction surface connection point and the pressure surface connection point, respectively. The third and fourth control points are points having coordinates that are determined as solutions of simultaneous equations obtained by applying continuity conditions for first to third differential coefficients at the first and sixth control points to a fifth order Bezier function.
US11333160B2
A propeller system combines innovative strategies to create a new methodology to reduce propeller or rotor noise. The propeller is specifically aimed for ultra-quiet electrically powered aircraft for use in high proximity aviation, but its low-noise advantages will extend to other purposes. The propeller blade includes geometries, along with size and operational limitations that minimize rotational and vortex noise, vibration and span-wise air flow on the blade. To further reduce noise, the propeller provides greater relative thrust on the inboard portions of the blade than do conventional propellers and provides less than conventional relative thrust including negative thrust at the outermost portions of the blade. The propeller blade includes stepped changes in local blade stiffness at calculated intervals that can reduce resonant blade vibrations and their resultant noise. This ultra-quiet propeller design can also be used for quieting hovercraft, drones, surveillance aircraft, indoor fans, wind tunnels and other applications.
US11333155B2
A thermal module including a first body, a second body, a first fan assembly, a second fan assembly, and a shaft is provided. The first body and the second body are slidably connected to each other and form an accommodating space together. The first fan assembly is disposed in the accommodating space and has a first hub and a plurality of first fan blades. The first hub is connected to the first body. The second fan assembly is disposed in the accommodating space and has a second hub and a plurality of second fan blades, and the second hub is connected to the second body. The first hub and the second hub overlap each other. The shaft is pivotally disposed in the first body and the second body and is engaged with the first fan assembly and the second fan assembly.
US11333148B2
A screw compressor according to an embodiment includes a rotor casing, a pair of screw rotors disposed in the rotor casing and engaging with each other, and a movable portion disposed so as to be movable in a rotor shaft direction of the pair of screw rotors. The movable portion includes liquefied liquid supply ports capable of supplying a liquefied liquid of a compressed gas toward tooth groove spaces formed by the pair of screw rotors.
US11333143B2
An oscillating positive displacement pump with at least one mobile part arranged to be movable relative to a fixed part. The mobile part is driven and drives a displacement element of the positive displacement pump. An electrodynamic drive is provided as a drive, on which a plurality of coils and permanent magnets are provided that are arranged on the mobile part of the drive respectively, and at least one guide member is provided on the drive, which allows the mobile part to move only along a degree of translation freedom. The positive displacement pump is designed as a diaphragm pump, which is associated with a measurement and control unit with a data storage and data processor, which processes a position signal of the mobile part and the strength of the drive current as a measured and/or control variable. An arrangement of a plurality of such positive displacement pumps and a method of operating at least one such oscillating positive displacement pump are also provided.
US11333139B2
The embodiments of the present disclosure relates a cryopump including a pump housing including a suction port, a cold head located within the pump housing, a shielding element located within the pump housing and covering the cold head, a baffle at the suction port, the baffle including a gas passage with an inlet and an outlet, an orthographic projection of the baffle to the cross section of the pump housing completely covers an orthographic projection of the suction port thereto, the gas passage includes a first portion and a second portion intersecting with each other, the inlet is defined by one end of the first portion, the outlet is defined by one end of the second portion.
US11333103B2
A nozzle having a forward portion skewed downwards and an aft portion translated downwards provides sufficient clearance between the nozzle and the heat shield structure to prevent contact in the event of large deflections (e.g., as associated with a fan blade Out (FBO) condition). Such large deflections must be accounted for to meet federal aviation regulations and gain airplane CFR 14 Part 25 Certification.
US11333102B2
A thrust reverser may include a frame, a track disposed on the frame, a carrier operatively coupled to the track, a first reverser door operatively coupled to the carrier, the first reverser door is movable relative to the frame, wherein the first reverser door is configured to move to a first position in response to the carrier moving with respect to the track in a first direction, and move to a second position in response to the carrier moving with respect to the track in a second direction, and a deployable fairing pivotally coupled to the frame, the deployable fairing operatively coupled to the carrier, wherein the deployable fairing is configured to move away from a central axis of the thrust reverser to provide clearance for the reverser door to rotate into a deployed position.
US11333101B2
An assembly with a piston reciprocated with the aid of a floating head in fluid communication with the piston. The assembly may utilize a floating head that is shifted in position to promote reciprocation of the piston through the aid of pressure supplied to the floating head from a pressure volume regulator. Alternatively, the floating head may be in fluid communication with the piston at one side of the head and isolated at the other side. In this manner changing volume and pressure at this other side of the head during reciprocation may ultimately lead to floating head movement toward the piston, thereby promoting the continued reciprocation. Additional efficiencies may also be realized through unique hydraulic layouts for both operating and working fluid circulations.
US11333099B2
A skip fire engine controller is disclosed that commands an early direct-injection of fuel during a skipped working cycle in which a cylinder is not exhausted. With early direct injection, the fuel has more time to vaporize and mix with air for combustion in an immediately following working cycle in which the cylinder is fired. By increasing the degree of vaporization and mixing, the combustion is both cleaner and more efficient.
US11333098B2
An engine controller calculates a pulsation correction value based on actuation states of an air bypass valve (ABV) and a wastegate valve (WGV) that change the shape of intake and exhaust flow passages of an exhaust turbocharger. The pulsation correction value is used to compensate for an output error of an airflow meter caused by intake pulsation. The engine controller also calculates a fuel injection amount of an injector, based on an output of the airflow meter that has been corrected based on the pulsation correction value.
US11333093B2
With respect to a vehicle mass air-flow sensor that includes a temperature sensor for measuring a temperature of a sensor element of the mass air-flow sensor, a method for controlling a heating element for heating the sensor element of a mass air-flow sensor includes identifying a dew formation on the sensor element by evaluating a temperature profile that is recorded during an operation of the vehicle using the temperature sensor, and generating a switch-on signal for switching on the heating element in response to the identification of the dew formation.
US11333091B2
A method of raising exhaust gas temperatures of a two-cycle uniflow scavenged engine at lower loads. At lower loads, the exhaust valves are activated with a frequency that is less frequent than every engine cycle. This exhaust valve deactivation may be combined with additional engine operating strategies, such as by using fewer than all cylinders as combusting cylinders, adjusting fueling to combusting cylinders, and reducing compressor output.
US11333081B2
A rotating machine control device is provided with: an operating terminal for changing a parameter of the rotating machine; a clearance measuring device which measures the amount of clearance between a rotor and a casing; and a control device body. The control device body, in accordance with the amount of clearance measured by means of the clearance measuring device, determines an operating amount for the operating terminal so as to vary the rate of change in the parameter, and outputs the operating amount to the operating terminal.
US11333077B2
A system (166) for transferring mechanical power in a turbine engine (150/151) including a low pressure spool (162) and a high pressure spool (156) includes a power transfer unit (168) coupled between an output shaft (172) of the low pressure spool (162) and a drive shaft (174) of the high pressure spool (156) to mechanically link the low pressure spool (162) to the high pressure spool (156), and a clutch (170) coupled to the power transfer unit (168), wherein the clutch (170) is configured to transfer power produced from the low pressure spool (162) to the high pressure spool (156).
US11333073B2
To prevent or reduce an oversensitive change in the degree of opening of a bleed valve regulating the flow volume of a cooling air used to heat a fuel. A gas turbine includes: a compressor compressing an air; a combustor burning a fuel mixed with the air compressed by the compressor; a turbine configured to be driven by a combustion gas generated by the combustor; a heat exchanger causing the fuel to be supplied to the combustor to be heated through a cooling air bled from the compressor to be supplied to the turbine; a bleed valve regulating the flow volume of the cooling air; a first sensor measuring a fuel state value; a second sensor measuring a cooling air state value; and a control computer controlling the degree of opening of the bleed valve. The control computer stores therein data on reference values and dead bands including the corresponding reference value set for each of the fuel state value and the cooling air state value, and, when a measured value of at least one of the fuel state value and the cooling air state value has changed so much away from the corresponding reference value as to fall outside the corresponding dead band, controls the bleed valve such that the changed measured value is brought close to the corresponding reference value.
US11333069B2
An electrochemical power system is provided that generates an electromotive force (EMF) from the catalytic reaction of hydrogen to lower energy (hydrino) states providing direct conversion of the energy released from the hydrino reaction into electricity, the system comprising at least two components chosen from: H2O catalyst or a source of H2O catalyst; atomic hydrogen or a source of atomic hydrogen; reactants to form the H2O catalyst or source of H2O catalyst and atomic hydrogen or source of atomic hydrogen; and one or more reactants to initiate the catalysis of atomic hydrogen. The electrochemical power system for forming hydrinos and electricity can further comprise a cathode, an anode, reactants that constitute hydrino reactants during cell operation with separate electron flow and ion mass transport, a source of oxygen, and a source of hydrogen. Due to oxidation-reduction electrode reactions, the hydrino-producing reaction mixture is constituted with the migration of electrons through an external circuit and ion mass transport through a separate path such as the electrolyte to complete an electrical circuit. In an embodiment, the anode is regenerated by intermittent charging with the electrodeposition of the anode metal ion from the electrolyte to the anode wherein an anion exchange with the anode metal oxide provides a thermodynamically favorable cycle to facilitate the electrodeposition.
A solid fuel power source that provides at least one of thermal and electrical power such as direct electricity or thermal to electricity is further provided that powers a power system comprising (i) at least one reaction cell for the catalysis of atomic hydrogen to form hydrinos, (ii) a chemical fuel mixture comprising at least two components chosen from: a source of H2O catalyst or H2O catalyst; a source of atomic hydrogen or atomic hydrogen; reactants to form the source of H2O catalyst or H2O catalyst and a source of atomic hydrogen or atomic hydrogen; one or more reactants to initiate the catalysis of atomic hydrogen; and a material to cause the solid fuel to be highly conductive, (iii) at least one set of electrodes that confine the fuel and an electrical power source that provides a short burst of low-voltage, high-current electrical energy to initiate rapid kinetics of the hydrino reaction and an energy gain due to forming hydrinos, (iv) a product recovery systems such as a condenser, (v) a reloading system, (vi) at least one of hydration, thermal, chemical, and electrochemical systems to regenerate the fuel from the reaction products, (vii) a heat sink that accepts the heat from the power-producing reactions, (viii) a power conversion system that may comprise a direct plasma to electric converter such as a plasma dynamic converter, magnetohydrodynamic converter, electromagnetic direct (crossed field or drift) converter, {right arrow over (E)}×{right arrow over (B)} direct converter, and charge drift converter or a thermal to electric power converter such as a Rankine or Brayton-type power plant.
US11333062B2
A pre-chamber for a fuel injector is disclosed. The pre-chamber includes a cylindrical body member extending axially from a first end portion to a second end portion opposite to the first end portion. The pre-chamber further includes a bottom plate located proximal to the first end portion of the cylindrical body member. The pre-chamber also includes a sacrificial member extending axially outwards from the second end portion of the cylindrical body member.
US11333059B2
A system comprising a computer including a processor and a memory, the memory including instructions such that the processor is programmed to: receive at least one of expected upcoming traffic behavior or actual upcoming traffic behavior corresponding to an upcoming segment of a roadway being traversed by a vehicle; adjust a radiator hysteresis timer based on the expected upcoming traffic behavior or the actual upcoming traffic behavior; and transmit a control signal to an actuator to actuate a radiator fan based on the adjusted radiator hysteresis timer.
US11333056B2
A gasoline particulate filter (GPF) diagnostic technique utilizes an upstream temperature sensor arranged at an upstream point relative to a GPF brick that the GPF is configured to house and configured to measure an upstream temperature of exhaust gas produced by an engine, a downstream temperature sensor arranged at a downstream point relative to the GPF brick and configured to measure a downstream temperature of the exhaust gas produced by the engine, and a controller configured to detect whether the GPF brick is damaged or missing based on a temperature difference between the upstream and downstream exhaust gas temperatures, a set of temperature thresholds, and a current operational mode of the engine.
US11333047B2
The present invention concerns an external heat source engine comprising: —at least one cylinder (2), —a piston (3) that is movable back and forth in the cylinder, —a cylinder head (4) defining a working chamber (5) with the piston and the cylinder, —a heat exchanger (6) for exchanging heat between a working gas and a heat-transfer fluid, —a distribution comprising two rotary slide valves (20, 30) mounted so as to be able to rotate in the cylinder head and bringing the working chamber selectively into communication with the following resources: •a working gas inlet (A), •a cold end (B) of the exchanger, •a hot end (C) of the exchanger, •an exhaust (D). The slide valves (20, 30) comprise internal passages that open through the side wall of same through at least one opening that communicates selectively with the working chamber (5) via at least one opening formed in the cylinder head (4).
US11333044B2
A steam turbine includes: a partition section that partitions a high-pressure stage and a low-pressure stage; and a pressure regulation valve that regulates a pressure of extraction steam. The pressure regulation valve includes: a plurality of flow rate regulation valves; and a plurality of flow path compartments that correspond to the respective flow rate regulation valves and that communicate with the low-pressure stage side relative to the partition section through respective nozzle holes. The plurality of flow path compartments are arranged over the entire partition section in a circumferential direction in a region including an outer peripheral side of the pressure regulation valve relative to the partition section as a whole. The partition section includes a bypass passage that makes the high-pressure stage side and the low-pressure stage side communicate with each other without passing through the pressure regulation valve.
US11333043B2
A steam turbine plant includes high-pressure gland portions, low-pressure gland portions, a gland regulator line, and a rotor-driving steam supply line. The high-pressure gland portions supply gland steam to gaps of ends of a high-pressure turbine rotor, and thereby seal the gaps. The low-pressure gland portions supply the gland steam to gaps of ends of a low-pressure turbine rotor, and thereby seal the gaps. The gland regulator line guides the gland steam from the high-pressure gland portion to the low-pressure gland portion. The rotor-driving steam supply line branches off from the gland regulator line, and supplies some of the gland steam to a main steam flow passage in a low-pressure casing.
US11333042B2
A turbine blade includes an airfoil that has a tip region that extends from the leading edge toward the trailing edge, and the tip region is bounded by a wall that extends at an angle. The leading edge has a leading edge cooling circuit that is defined from the platform to a tip flag channel, and the leading edge cooling circuit is in fluid communication with the tip flag channel. The pressure side includes at least one tip dust hole defined through the wall proximate the pressure side, and the at least one tip dust hole has an inlet and an outlet. The airfoil has at least one rib defined on the wall that extends at a second angle to direct the particles and a portion of the cooling fluid into the inlet.
US11333034B2
A nozzle vane for a variable geometry turbocharger has an airfoil including a leading edge, a trailing edge, a pressure surface, and a suction surface at least in a center position in a blade height direction. The airfoil satisfies 0≤Wmax/L<0.03, where Wmax is a maximum value of a distance from a line segment connecting the trailing edge and a fixed point on the pressure surface at a 40% chord position from the trailing edge toward the leading edge to a given point on the pressure surface between the trailing edge and the fixed point, and L is a length of the line segment.
US11333033B2
A method (400) of measuring rotor blade tip deflections of turbomachine rotor blades (R1, R2) during operation using Blade Tip Timing (BTT) includes measuring (402), by a proximity sensor (202), a proximity signal caused by a moving rotor blade (R1, R2) and determining (412), by a control module (212), a Time-of-Arrival (ToA). The method (400) includes measuring a time that the shaft starts to rotate a measurable angular distance and a time the shaft has completed its rotation of the measurable distance and storing (406) timing data indicative of a plurality of ToA measurements of the rotor blade (R1, R2) and the zero crossing times. The method (400) includes determining the shaft Instantaneous Angular Position (IAP) between at least two zero crossing times, which determination comprises expressing the shaft IAP between at least two zero crossing times as a continuous, non-constant IAP mathematical function of time, with unknown function coefficients and calculating the unknown function coefficients of the IAP mathematical function.
US11333023B2
A gas turbine engine article includes a cooling passage network embedded in an article wall between inner and outer portions of the article wall. The network has an inlet orifice through the inner portion to receive cooling air from a cavity, a sub-passage region that includes an array of pedestals, and at least one outlet orifice through the outer portion. The array of pedestals includes first pedestals arranged in a first row and second pedestals arranged in a second, adjacent row. The first pedestals and the second pedestals define inter-row sub-passages there between. Each of the inter-row sub-passages has an inlet mouth, an outlet mouth, and a compound channel connecting the inlet mouth and the outlet mouth. The compound channel includes a first channel length over which the inter-row sub-passage has a constant cross-section and a second channel length over which the inter-row sub-passage has a non-constant cross-section.
US11333017B2
This disclosure relates to a separating a fluid having multiple phases during formation testing. For example, certain embodiments of the present disclosure relate to receiving contaminated formation fluid on a first flow line and separating a contamination (e.g., mud filtrate) from the formation fluid by diverting the relatively heavier and/or denser fluid (e.g., the mud filtrate) downward through a second flow line and diverting the relatively lighter and/or less dense fluid upward through a third flow line. In some embodiments, the third flow line is generally oriented upwards at a height that may facilitate the separation of the heavier fluid from the relatively lighter fluid based on gravity and/or pumps.
US11333015B2
An apparatus for determining properties of an uncharacterized downhole fluid. The apparatus comprises an oscillation driver circuit comprising an amplifier having an output and an input, a feedback loop between the output and input of an amplifier or a logic gate, an electromechanical resonator disposed within the feedback loop such that a the resonator is driven by the oscillation driver circuit, wherein a resonant frequency of the resonator defines an oscillation frequency of the oscillator circuit, and a switch device for causing the oscillator circuit to stop driving the resonator, which thereby enables observation of a decay rate of the oscillation of the electromechanical resonator within the uncharacterized fluid. The electromechanical resonator is enclosed in a conductive layer to protect the resonator against capacitive effects of the downhole fluid.
US11333010B2
A choke valve system operable to obtain sand production measurements from a sand production sensor, compare the sand production measurements to a target sand production range for a current setting of a choke valve, and, in response to determining that the sand production measurements are outside of the target sand production range, adjust the setting of the choke valve in an effort to bring the sand production of the well into a target sand production range, and generate an alert regarding the out of range sand production measurements and the corresponding adjustment of the choke valve.
US11333003B2
A setting tool for opening and dosing a sleeve inside a casing includes a body extending along a central longitudinal axis (X); a set of holding dogs located around the body; and a set of sleeve dogs located around the body. The set of sleeve dogs are configured to move along the central longitudinal axis (X) relative to the set of holding dogs.
US11333001B2
A diverter for obstructing and temporarily sealing a perforation in a well casing in a subterranean formation during hydraulic fracturing. The diverter comprises an outer surface and circuitry within the outer surface for determining a pressure proximate the diverter.
US11332998B2
An integrated managed pressure drilling (“MPD”) riser joint includes an annular sealing system that allows for the installation, engagement, service, maintenance, disengagement, removal, or replacement of one or more sealing elements while maintaining a pressure tight seal on the annulus without a drill string isolation tool, or equivalent thereof. The integrated MPD riser joint is limited to the annular sealing system and a flow spool, or equivalent thereof, disposed directly below the annular sealing system, without any intervening pressure containment devices or systems. Advantageously, the integrated MPD riser joint does not require a drill string isolation tool, or equivalent thereof, and may be substantially shorter in length and weigh substantially less than a conventional integrated MPD riser joint. The reduction in size and weight enables adoption of MPD technology in applications where conventional integrated MPD riser joints are not economically feasible or are otherwise precluded from use.
US11332984B2
Embodiments of the present invention disclose a standoff assembly for a sucker rod used for sucker rod pumps. The assembly includes an annulus body, a hole that passes through the annulus body, the hole configured to permit a sucker rod to translate through the hole, a sliding material component located along the surface of the hole, and a temporary component; wherein upon elimination of the temporary component, the sliding material component interacts with the sucker rod to reduce sliding friction as the sucker rod translates through the assembly.
US11332982B2
A double shoulder threaded tool joint connection includes a pin with external threads formed between a pin external shoulder and a pin internal shoulder, the pin including a nose section between the pin internal shoulder and the pin external thread and a box with internal threads formed between a box external shoulder and a box internal shoulder. The internal threads and the external threads are arranged and designed for connection with each other so that the box and the pin are connected with a common center-line and with a primary seal formed by the pin external shoulder forced against the box external shoulder and a secondary seal formed between the pin internal shoulder forced again the box internal shoulder. The invention may be applied to any threaded joint.
US11332979B2
The disclosed embodiments relate to a rotary steering having a plurality of hydraulically actuated steering pad assemblies and a valve positioned between a primary flow channel of the rotary steering tool and an actuating piston of each of the plurality of steering pad assemblies. The representative valve includes a two-disk valve, with an uphole disk having a single, fixed-area aperture and a downhole disk having a plurality of independently variable-area orifices. Each of the independently variable valve orifices corresponds to one of a plurality of valve ports. In turn, each valve port being is fluidly coupled to, and operable to actuate, a corresponding piston of one of the plurality of steering pad assemblies. The independently variable-area orifices can be manipulated (gradually opened or closed) to vary the pressure drop across the tool, and thereby vary the magnitude of hydraulic force available to actuate the steering pad assemblies.
US11332978B1
A rotary transfer mechanism is disclosed for a motor, pump, or other downhole tool that accommodates the eccentric motion of a rotor without the need for a flex shaft, articulating joint or CV joint. In one configuration, the rotor is coupled to the drive shaft at a radial offset from the drive shaft axis. The orbiting motion of the rotor, rather than rotation of the rotor about its own axis, generates a torque on the drive shaft, by applying a tangential force to the drive shaft at the location of the radial offset. The radial offset may be set equal to the orbital radius so that no radial movement or flex is required at the drive shaft to accommodate the eccentric rotor movement.
US11332977B2
An equipment holder for mounting on an access device of a vehicle, such as on a side rail of a retractable stair or ladder of the vehicle. The holder can be configured to hold one or more wheel chocks and/or one or more fire extinguishers. The holder can be mounted by a unique mounting bracket. Other equipment may be carried in the holder e.g. one or more radio communications handsets, first aid equipment, protective clothing (such as a hard hat, weatherproof jacket) or a tool kit, or combinations of two or more thereof. The holder can include a cradle or rack mounted to the access device by the mounting bracket.
US11332970B2
A laundry appliance includes a cabinet and a door rotatably coupled to the cabinet. The door is operable between an opened position and a closed position. A door opening assembly is coupled to one of the cabinet and the door. The door opening assembly includes a motor coupled to a cam. The cam is operably coupled to an actuator arm.
US11332961B2
An exemplary electronic actuator assembly is configured for use with a pushbar assembly having a drive assembly operable to retract a latchbolt, and includes an input shaft, a motor, and a boost spring. The motor has a retracting state in which the motor drives the input shaft from a proximal position to a distal position, a holding state in which the motor exerts a holding force to retain the input shaft in the distal position, and a releasing state in which the motor exerts a residual force that resists movement of the input shaft. The boost spring exerts a boost force urging the input shaft in the proximal direction to at least partially counteract the residual force.
US11332960B2
In one aspect the present invention provides a door strike which prevents the opening of an associated door when the door strike has been heated to an elevated temperature of at least about 1000° F., preferably when the door strike is at higher temperatures such as are present during a fire in a building structure. The door strike includes a thermally responsive element which retards the normal operation of the door strike when it is at an elevated temperature. A further aspect of the invention is a method for controlling the undesired spread of a fire or smoke between adjacent spaces separated by the door wherein a fire or smoke condition exists in at least one of these spaces, via the provision of a door strike having a thermally responsive element which retards the normal operation of the door strike when it is at an elevated temperature.
US11332956B2
A rose assembly for a door lock and a method of removably securing the rose assembly to a lock chassis. The rose assembly is secured to the lock chassis through the use of an intermediate spring steel attaching plate, which provides both a secure attachment to the lock and orientation of the rose assembly to the lock housing. A single spring plate with integrated retention clip features provides a removably attachable interface between the rose and the lock chassis. The spring plate includes a hook feature to provide positive retention of the rose that is independent of the spring clip features. Additionally, the spring clips are located to minimize the possibility that one clip deflects substantially more than another. The installation process includes inserting the hook feature into a slot in the chassis housing, and then snapping the clip features over the housing to seat and retain the rose.
US11332955B2
A tool for extracting tent stakes from the ground is disclosed. The tool has a portion that houses the motor and hydraulic fluid tank, and a hydraulic cylinder portion the user holds against a tent stake and operates to pull the tent stake. Hydraulic hoses connect the two portions. Separating the motor from the hydraulic cylinder allows the user to manipulate just the portion performing work on the tent stake without having to also lift or stabilize the larger and heavier motor portion. Rotating a handle causes the hydraulic cylinder to extend or retract. A hand guard may be present to prevent accidental crush injuries. The tool is designed to fully extract a stake in two strokes of the hydraulic cylinder.
US11332951B2
Apparatus, systems, and methods for a pool filtration system including a basket with a flexible netting that is customizably designed and versatile in its functionality. The basket can be made from modern plastic or plastic-like materials. The weather-resistant, durable materials benefit the netting design for capturing and holding debris in a pool filtration system.
US11332943B2
Disclosed herein, among other things, are system, methods and apparatuses for wall coverings with adjustable spacing. One aspect of the present subject matter relates to a concrete wall panel including a mounting system that includes a decorative panel with a flange embedded within the panel, the flange having mounting features providing for a number of ways to mount a plurality of such panels to a wall or other planar surface. The mounting system allows for fasteners to be used to connect the wall panel to a wall and provides a mount that has an air gap to allow for air to flow and for any moisture to pass between the wall inner surface and behind the wall panels.
US11332936B1
A rebar support chair has a housing with first and second opposed boundary walls spaced apart from one another and defining a cavity therebetween, an attachment portion having a seat for supporting rebar, a dampening member, and a force dispersion member inside the cavity. The attachment portion transfers forces between the rebar and housing. The force dispersion member moves in response to vibration of the attachment portion, and movement of the force dispersion member corresponds with compression and decompression of the dampening member. Another rebar support chair has a housing defining a cavity, an attachment portion for supporting rebar, a dampening member, and a force dispersion member in the cavity. The attachment portion transfers forces between the rebar and housing. The force dispersion member moves from a rest position in response to vibration of the attachment portion, and the dampening member biases the force dispersion member toward the rest position.
US11332933B2
The present technology relates to beams having a cross section defining a plurality of channels and assemblies comprising the beams. The beams can be used to form a beam assembly that is installed inside the truck bed of a pick-up truck. A ladder loader and a solar panel assembly can be pivotably secured to the beam assembly along either the driver side wall or the passenger side wall of the truck bed.
US11332927B2
A building formwork component comprising first and second spaced sidewalls having one or more webs extending there-between, each sidewall comprising a flange extending inwardly along a first edge of the sidewall such that an outer surface of the flange forms a ramp surface; and a groove extending along an opposing second edge of the sidewall. The component may be coupled to a like component by relative movement of the components towards each other, whereby the flanges are received in respective grooves of the like component, and whereby the ramp surfaces facilitate such coupling by engaging respective second edges of the like component to move the second edges and/or ramp surfaces for engagement of the flanges in the grooves.
US11332916B2
A flush toilet includes a bowl part and a water storage part. The bowl part receives waste. The water storage part is formed on a bottom of the bowl part and stores a stored water. The water storage part includes a front surface part, a back surface part that is formed on a back side of the front surface part, and a pair of side surface parts that are formed between the front surface part and the back surface part. On at least one side surface part in the pair of side surface parts, a convex surface that protrudes toward another side surface part is formed.
US11332910B2
This description provides an autonomous or semi-autonomous excavation vehicle that is capable of navigating through a dig site and carrying an excavation routine using a system of sensors physically mounted to the excavation vehicle. The sensors collect one or more of spatial, imaging, measurement, and location data representing the status of the excavation vehicle and its surrounding environment. Based on the collected data, the excavation vehicle executes instructions to perform an excavation routine by excavating earth from a hole using an excavation tool positioned at a single location within the site. The excavation vehicle is also able to carry out numerous other tasks, such as checking the volume of excavated earth in an excavation tool, navigating the excavation vehicle over a distance while continuously excavating earth from a below surface depth, and preparing a digital terrain model of the site as part of a process for creating the excavation routine.
US11332906B2
A grout plug assembly for use in forming a pipe pile system defining at least one pile assembly inner surface portion comprises a resiliently deformable plug body and a substantially rigid plug cap. The resiliently deformable plug body defining a plug outer surface, a plug inner surface, a first plug end surface, a second plug end surface, where the plug inner surface defines a plug passageway. The substantially rigid plug cap defines a cap outer surface, a cap inner surface, a first cap end surface, and a second cap end surface. The second cap end surface is rigidly secured to the first plug end surface. The plug outer surface is sized and dimensioned to engage the at least one pile assembly inner surface portion of the pipe pile system during formation of the pipe pile system.
US11332905B2
The present disclosure regards a pile for a pile wall, said pile extending longitudinally between a first and a second end and comprising at least one perimeter profile in a cross section being essentially perpendicular to the longitudinal extension of said pile, said perimeter profile enclosing an uninterrupted area in said cross section, wherein at least one section of the perimeter profile extends outwardly forming a first male connection portion, and the uninterrupted area extends into the first male connection portion, thereby forming a load bearing portion of the pile. Furthermore, the present disclosure also regards a connection arrangement and a manufacturing method.
US11332904B2
The present invention provides a lateral and continuous measurement method for soil parameters in a soft soil field. The method mainly comprises the following measurement steps: arranging soil strength measuring apparatuses at the front end of a towing apparatus; arranging soil strain softening relationship measuring apparatuses at the bottom end of the towing apparatus; and measuring interface friction parameters between the soil and a structure. The towing apparatus actively or passively moves in a soft soil layer to ensure that the towing apparatus partially penetrates into the to-be-measured soil layer during movement; and the penetration depth of the towing apparatus is controlled by adjusting counterweight above the towing apparatus and a towing angle.
US11332900B2
A sweeping blade assembly includes a sweeping blade device and is configured to be attached to a plow blade of a vehicle for sweeping a ground surface. The assembly comprises a blade support which is securable to the plow blade and a plurality of sweeping blade devices which can be mounted to the blade support. Each sweeping blade device includes a blade main section and a wear block which can be attached to a front section of the blade main section in a lower portion thereof. The wear block(s) can optionally have at least one cut-out section(s) extending upwardly from a scraping edge of the wear block and can define at least two spaced-apart teeth in the lower portion of the wear block.
US11332897B2
A multicomponent bridge support system includes: a base portion configured to make contact with bearing soil/strata/bedrock; a support portion configured to engage a bridge deck; and one or more precast intermediate portions configured to space the support portion with respect to the base portion.
US11332887B2
A tailings-reclaimed green stone paper processing method, which treats the tailings to meet the pH 7 pH requirement of the paper standard, grinds the treated tailings after drying, modifies the powdered tailings, implements a modified granulation process with the use of a modification aid, and then implements plastic granule stirring, heating mixing, filament spinning, cutting, papermaking and surface treatment processes to form an environmentally friendly stone fiber paper product, achieving the effects of tailings reuse, pollution-free, moisture-proof, anti-mite and low cost.
US11332876B2
A fabric treating appliance includes a cabinet defining an interior and having a top wall defining an access opening. A cover is provided that is movable relative to the cabinet between an open position and a closed position to selectively close the access opening. A tub is located within the interior and includes and open top aligned with the access opening. A rotatable basket is located within the tub and has a loading opening aligned with the open top and the access opening. A top wall extends between the cabinet and the tub.
US11332874B2
A washing machine appliance, as provided herein, may include a cabinet, a tub, a basket, and a fluid additive dispenser. The fluid additive dispenser may include a housing and a dispenser drawer. The housing may extend between an open front end and a closed rear end. The housing may be disposed within the cabinet. The dispenser drawer may be selectively received in the housing above the basket. The dispenser drawer may extend from a forward end proximate to the rotation axis to a rearward end distal to the rotation axis. The dispenser drawer may define a primary compartment and a pod compartment adjacent to the primary compartment between the forward end and the rearward end. The dispenser drawer may further define a pod outlet extending through a wall of the pod compartment to direct a wash fluid therefrom.
US11332872B2
Provided is a drum washing machine. The drum washing machine, which is provided with a rotating body on the rear a drum, is able to smoothly switch between a first form in which the drum and the rotating body rotate independently and a second form in which the drum and the rotating body rotate integrally. When switching from a biaxial driving form to a uniaxial driving form and vice versa, a control part rotates a rotor clockwise and anticlockwise in a manner of taking a reverse action 1 and a reverse action 2 during the operation of a torque motor, i.e., during an action of moving a clutch body by virtue of a moving mechanism. The reverse action 1 includes an action of stopping the rotor rotating clockwise direction, and the reverse action 2 includes an action of stopping the rotor rotating anticlockwise.
US11332871B2
A washing machine includes a casing, a tub, a drum, a pump for circulating water from the tub, a gasket connecting an entry hole of the casing to an entrance hole of the tub and including nozzles for spraying water to the drum, and distribution pipes for supplying water to the nozzles. The nozzles are arranged at both lateral sides of the gasket in a vertical direction. The distribution pipes are arranged at an outer circumferential surface the gasket and coupled to receiving pipes that protrude from the gasket. The distribution pipes include an inlet port and outlet ports disposed in the vertical direction corresponding to the nozzles.
US11332866B2
A laundry treatment machine may include an outer tub having an opening at a top through which laundry is inserted. The outer tub may contain wash water for washing the laundry. An inner tub may be rotatably provided inside the outer tub. A pulsator may be rotatably provided at a bottom of the inner tub to generate a current or flow of water flowing at a lower part of the inner tub. A water current generating protrusion that protrudes inward from a peripheral surface of the inner tub and extends upward from a bottom end of the inner tub may generate a current or flow of water flowing along an upper part of the inner tub.
US11332863B2
The present invention relates to non-woven fabric with enhanced hardness and sound absorption, more specifically to non-woven fabric that includes two or more kinds of polyester-based materials and non-circular cross-section fiber, and thus has enhanced hardness and sound absorption as well as improved formability, and that can be applied for an automotive undercover.
US11332861B2
Methods for characterizing a nanotube formulation with respect to one or more particular ionic species are disclosed. Within the methods of the present disclosure, this characterization provides control over the surface roughness (or smoothness) and the degree of rafting within a nanotube fabric formed from such a nanotube formulation. In one aspect, the present disclosure provides a nanotube formulation roughness curve (and methods for generating such a curve) that can be used to select a utilizable range of ionic species concentration levels that will provide a nanotube fabric with a desired surface roughness (or smoothness) and degree of rafting. In some aspects of the present disclosure, such a nanotube formulation roughness curve can be used adjust nanotube formulation prior to a nanotube formulation deposition process to provide nanotube fabrics that are relatively smooth with a low degree of rafting.
US11332859B2
A textile sleeve for routing and protecting elongate members and method of construction thereof is provided. The sleeve includes an elongate, braided wall having a circumferentially continuous, tubular outer periphery extending along a central axis between opposite open ends. The wall includes shrinkable yarns and non-shrinkable yarns. The shrinkable yarn provides the wall with an ability to be radially contracted from a first, diametrically enlarged assembly state to a second, diametrically shrunken state.
US11332850B2
The present disclosure provides shuttle vectors for editing exogenous polynucleotides in heterologous live cells, as well as automated methods, modules, and multi-module cell editing instruments and systems for performing the editing methods.
US11332848B2
An embodiment provides a silicon single crystal growth method comprising the steps of: (a) allowing the shoulder of a single crystal to grow vertically; (b) allowing the shoulder to grow horizontally after the vertical growth; and (c) allowing the shoulder to grow in a downward convex shape after the horizontal growth of the shoulder, wherein the shoulder grows at a preset rate on the basis of the final diameter of the shoulder and the shoulder growth height according to steps (b) and (c).
US11332842B2
To provide an aluminum surface treatment method for manufacturing a polymer-aluminum joint structure having excellent bond strength. An aluminum surface treatment method for bonding with a polymer composite which is characterized in that it includes (a) a primary anodizing treatment step wherein the aluminum surface is treated by anodic oxidation; (b) a step wherein the aluminum oxide film is removed from the aluminum that has undergone the primary anodizing treatment; and (c) a secondary anodizing treatment step wherein the aluminum from which the aluminum oxide film is removed following the primary anodizing treatment is treated by anodic oxidation again.
US11332834B2
The present invention relates to a catalyst and a manufacturing method thereof, the catalyst is characterized that a distance between a transition metal of a transition metal oxide nanoparticle and oxygen is controlled by substituting at least a part of surface of the transition metal oxide nanoparticle with an inclusion.
US11332832B2
Disclosed is a method for the management of fluids required to operate a fixed or mobile installation, the method including an operation of the anodic oxidation of a solution of hydrogen peroxide (P) for the purpose of producing oxygen, water and hydrogen cations by subjecting the solution to an electric current produced by an electrical power source. Also disclosed is a device that makes it possible to implement the method.
US11332829B2
Introduced here is a plasma polymerization apparatus and process. Example embodiments include a vacuum chamber in a substantially symmetrical shape relative to a central axis. A primary rotation shaft may be operable to rotate about the central axis of the vacuum chamber and a secondary rotation shaft may be operable to rotate about a secondary axis distal to the central axis. The primary and secondary rotation shafts may be mechanically connected, and one or more devices may be secured on a platform that rotates along both shafts. Additionally, reactive species discharge mechanisms positioned around a perimeter of the vacuum chamber may be configured to disperse reactive species into the vacuum chamber. The reactive species may form a uniform polymeric multi-layer coating on the surface of the one or more devices.
US11332824B2
A method for reducing effluent buildup in a pumping exhaust system of a substrate processing system includes, during a substrate treatment process, arranging a substrate on a substrate support in a processing chamber; supplying one or more process gases to the processing chamber; supplying an inert dilution gas at a first flow rate to the pumping exhaust system; performing the substrate treatment process on the substrate in the processing chamber; evacuating reactants from the processing chamber using the pumping exhaust system. The method includes, after the substrate treatment process, supplying cleaning plasma including cleaning gas in the processing chamber during a cleaning process; and supplying the inert dilution gas at a second flow rate that is less than the first flow rate to the pumping exhaust system during the cleaning process.
US11332814B2
A high-strength and high-toughness magnesium alloy includes a Mg—Al—Bi—Sb—Zn—Sr—Y—Mn alloy, prepared from the following components in percentage by mass: 7.0 to 10.0% of Al, 0.2 to 2.0% of Bi, 0.2 to 0.8% of Sb, 0.2 to 0.5% of Zn, 0.1 to 0.5% of Sr, 0.03 to 0.3% of Y, 0.05 to 0.1% of Mn and a balance of Mg.
US11332806B2
A method for desulfurization and dezincification of tailings includes the step of passing tap water into a high oxidation reduction electrocatalytic water equipment to reduce the pH value of tap water to 1-2, mixing a specific ratio of the pH value 1-2 acid electrocatalytic water with low-quality high-sulfur iron in the tailings, heating the mixture to let H+ in the acid electrocatalytic water be reacted with sulfur and zinc in the low-quality high-sulfur iron and to further cause generation of an ion state of hydrogen sulfide gas where the volatilization of water vapor effectively removes the sulfur and zinc elements in the low-quality high-sulfur iron and the hydrogen sulfide gas thus generated is collected.
US11332801B2
To provide a grain-oriented electrical steel sheet that has better magnetic property than conventional ones without requiring high-temperature slab heating, in the case of not performing intermediate annealing, the hot rolled steel sheet obtained by a predetermined step is subjected to hot band annealing, and, in a heating process in the hot band annealing, heating is performed at a heating rate of 10° C./s or less for 10 sec or more and 120 sec or less in a temperature range of 700° C. or more and 950° C. or less, and in the case of performing the intermediate annealing, in a heating process in final intermediate annealing, heating is performed at a heating rate of 10° C./s or less for 10 sec or more and 120 sec or less in a temperature range of 700° C. or more and 950° C. or less.
US11332783B2
The present invention provides a combination of genomic and computational technologies to provide rapid, portable sample analysis for sequencing or identifying a target sequence involving generating probes for use in analyzing a sample which may comprise a target sequence.
US11332780B2
Methods of detecting target polynucleotide sequences may include introducing one or more nucleic acid analytes to a first reaction mixture comprising a single-stranded probe oligonucleotide A0, a pyrophosphorolysing enzyme, and a ligase. The analyte may anneal to the single-stranded probe oligonucleotide A0 to create a first intermediate product which is at least partially double-stranded, where the 3′ end of A0 forms a double-stranded complex with the analyte and where A0 is pyrophosphorylsed in the 3′-5′ direction from the 3′ end to create at least a partially digested strand A1. A1 may undergo ligation to form oligonucleotide A2. The methods may also include detecting a signal derived from the formed oligonucleotides, and inferring therefrom the presence or absence of the target polynucleotide sequence in the analyte.
US11332779B2
Methods are provided for nucleic acid analysis wherein a target nucleic acid is mixed with a dsDNA binding dye to form a mixture. Optionally, an unlabeled probe is included in the mixture. A melting curve is generated for the target nucleic acid by measuring fluorescence from the dsDNA binding dye as the mixture is heated. Dyes for use in nucleic acid analysis and methods for making dyes are also provided.
US11332763B2
This disclosure describes methods that allow for the uncoupling of microbial growth from product formation, which allows for maximal use of raw material and optimal end-product formation.
US11332762B2
The invention includes methods, apparatus, and systems for the conversion of hydrogen together with carbon dioxide or carbon monoxide to methane using a population of microbes and a defined liquid medium. The microbial population maintains the amount of nutrients in the liquid medium within a relative range without requiring replenishment of the nutrients. Methods and apparatus for enriching the microbial population are also described.
US11332759B2
The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.
US11332754B2
Methods for improving transgene in chloroplasts are disclosed along with improved transgenes so produced and methods of use thereof for the treatment of disease. Specifically, the methods comprising analyzing the native sequence of a nucleic acid encoding a protein of interest and replacing codons in said sequence with those preferentially used in psbA genes in chloroplasts in higher plants.
US11332753B2
The present invention generally relates to methods and materials involved in producing tobacco plants having reduced levels of conversion of nicotine to nornicotine. In certain embodiments, the invention is directed to mutations in a nicotine demethylase gene, tobacco plants comprising mutations in a nicotine demethylase gene, and tobacco compositions and products thereof. In other embodiments, the invention is directed toward nicotine demethylase RNA interference, tobacco plants comprising a nicotine demethylase RNA interference transgene, and tobacco compositions and products thereof.
US11332747B2
Bispecific aptamers having a first end that specifically binds to a first tumor specific marker, tumor antigen, or viral protein and a second end that specifically binds to a second tumor specific marker, tumor antigen, or viral protein are provide. The bispecific aptamers can be used to treat cancer or virally infected cells. Generally, the bispecific aptamers bind to two surface proteins, preferably different proteins, on the same cell. In a preferred embodiment the bispecific aptamers bind to two different tumor markers, tumor antigens, tumor specific proteins and combinations thereof.
US11332746B1
Provided are compounds, methods, and pharmaceutical compositions for reducing the amount or activity of LRRK2 RNA in a cell or animal, and in certain instances reducing the amount of LRRK2 protein in a cell or animal Such compounds, methods, and pharmaceutical compositions are useful to ameliorate at least 5 one symptom or hallmark of a neurodegenerative disease. Such symptoms and hallmarks include ataxia, neuropathy, and aggregate formation. Such neurodegenerative diseases include Parkinson's disease.
US11332743B2
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ANGPTL3 gene, as well as methods of inhibiting expression of ANGPTL3 and methods of treating subjects having a disorder of lipid metabolism, such as hyperlipidemia or hypertriglyceridemia, using such dsRNA compositions.
US11332740B2
Provided herein are methods, systems, and compositions for seamless nucleic acid assembly. Methods, systems, and compositions as provided herein provide for efficient assembly of nucleic acids without primer removal. Methods, systems, and compositions for seamless nucleic acid assembly comprise use of an endonuclease or exonuclease, optionally in conjunction with additional enzymes to assemble nucleic acids or polynucleotides.
US11332738B2
Provided herein are methods, systems, and compositions for efficient nucleic acid assembly. Nucleic acid assembly may comprise assembly of variants comprising paired homology.
US11332733B2
The present disclosure provides oligomeric compound comprising a modified oligonucleotide having a central region comprising one or more modifications. In certain embodiments, the present disclosure provides oligomeric compounds having an improved therapeutic index or an increased maximum tolerated dose.
US11332731B2
The disclosure discloses a nitrile hydratase mutant, a genetically engineered bacterium containing the mutant and applications thereof, and belongs to the technical field of enzyme engineering. In the disclosure, glycine at position 47 of a nitrile hydratase mutant αL6T/A19V/F126Y-βM46K/E108R/S212Y (disclosed in the patent of disclosure CN102216455A) is mutated to asparagine. The obtained new mutant enzyme has better temperature tolerance and tolerance to a product, and is conducive to future industrial production. The recombinant strain containing the nitrile hydratase mutant is fermented at high density, and 3-cyanopyridine is used as a substrate to carry out a whole-cell catalytic reaction to prepare nicotinamide. Compared with a chemical production method, the method has a safe and clean production process and no environmental pollution. Compared with an enzymatic method, the substrate price is cheap and the catalytic efficiency is high. The yield of the final product nicotinamide is over 95%, the concentration reaches 680 g/L, and the separation and purification steps of the product are simplified.
US11332724B2
The present invention provides genetically engineered host organisms capable of producing terpenoids. The present invention also relates terpenoids obtained from such genetically engineered organisms. Examples of the produced terpenoids include carotenoids, ionones, abienol, and other isoprenoid derived compounds. In addition, the invention relates to a methods of for the preparation of terpenoids using such a genetically engineered organism.
US11332718B2
The present invention relates to the production of avian induced pluripotent stem cells from non-pluripotent somatic cells, including embryonic fibroblasts and adult somatic cells. In this method, avian (including quail or chicken) somatic cells are reprogrammed into a state closely resembling embryonic stem cells including the expression of key stem cell markers alkaline phosphatase, etc. by transfecting/transducing the non-stem cells with genes (preferably using a non-integrating vector as otherwise described herein or alternatively an integrating vector, such a lentiviral vector, retroviral vector or inducible lentiviral vector, among others) which express at least nanog, Lin28 and cMyc. In preferred aspects of the invention, the transfected/transduced vectors express nanog, Lig28, cMyc, Oct 4 (POU5F1 or PouV), SOX2 and KLF4. The induced stem cells which are produced contribute to all 3 germ layers, the trophectoderm and in certain aspects, the gonad in chimeric offspring.
US11332715B2
Disclosed is a method for culturing mesenchymal stem cells, comprising culturing mesenchymal stem cells in a medium containing calcium in a concentration of from 2.1 to 3.8 mM and magnesium in a concentration of from 1.0 to 3.0 mM under a hypoxic condition of 2 to 5% oxygen. The culturing method can increase the population of mesenchymal stem cells even with a small number of passages by improving mesenchymal stem cells in proliferative capacity and viability. In addition, the mesenchymal stem cells prepared by the culturing method are effectively used to treat or improve a pulmonary disease.
US11332713B2
The present disclosure provides methods and compositions related to the modification of immune effector cells to increase therapeutic efficacy. In some embodiments, immune effector cells modified to reduce expression of one or more endogenous target genes, or to reduce one or more functions of an endogenous protein to enhance effector functions of the immune cells are provided. In some embodiments, immune effector cells further modified by introduction of transgenes conferring antigen specificity, such as exogenous T cell receptors (TCRs) or chimeric antigen receptors (CARs) are provided. Methods of treating a cell proliferative disorder, such as a cancer, using the modified immune effector cells described herein are also provided.
US11332711B1
Described herein are compositions and methods to cryopreserve sporozoites. In some aspects, the method can include the step of placing harvested salivary glands containing sporozoites into an insect-based medium.
US11332707B2
An endophytic fungus from gingko, that is, Fusarium proliferatum DZHQ1 having antitumor activity and antibacterial activity, is isolated from the ginkgo bark. The species of the strain is determined by the combination of colonial morphology and 18 sRNA sequencing, and then the anti-cervical cancer activity of a crude extract of the strain is detected by MTT. Finally, a secondary metabolite of the strain with an inhibition rate of more than 50% is isolated by semi-preparative HPLC, which promotes the further screening of individual compounds with anti-tumor activity. Moreover, the metabolite of the endophytic fungus from gingko shows a more pronounced inhibition in the detection of activity against E. coli and/or S. aureus, and has potential use in the preparation of new antibacterial products.
US11332706B2
Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.
US11332703B2
A grape treatment and wine making process characterised by the steps of: cleaning a first container by means of a fluid mixed with ozone; placing the grapes in said first container in closed vats and/or buildings at controlled temperature; diffusing a fluid mixed with ozone within said vats and/or buildings at controlled temperature; cleaning said grapes placed in said first container by means of a fluid mixed with ozone; cleaning a press by means of a fluid mixed with ozone; pressing said grapes with said press to produce must; cleaning a second container by means of a fluid mixed with ozone; placing said must in said second container to produce fermented must; cleaning a third container by means of a fluid mixed with ozone; placing said fermented must (wine) in said third container.
US11332700B2
The present invention relates to the use of branched polyesters obtainable by polycondensation of citric acid with at least one polyalcohol, and optionally with polycarboxylic acid component as additive in washing compositions, cleaners, detergents or a formulation for water treatment and to mixtures comprising such branched polyesters. The invention further relates to the use of hydrophobically modified branched polyesters; and to the method for cleaning, washing or water treatment using such branched polyesters.
US11332698B2
The present invention provides a treatment agent composition for textile products, containing the following component (A) and the following component (B): component (A): an internal olefin sulfonate having 16 or more and 24 or less carbons; and component (B): a softening base for textile products.
US11332689B2
The present disclosure relates to a lubricating fluid for an electric motor system and a method of lubricating gears and cooling a motor in an electric motor system. In particular, the disclosed technology relates to a lubricating fluid, for use in electric motor vehicle, comprising an oil of lubricating viscosity and at least one phosphorylated dispersant exhibiting increased resistivity after aging.
US11332686B2
A fluorine-containing ether compound represented by formula (1) shown below. R4—CH2—R3—CH2—R2—CH2—R1—CH2—R2—CH2—R3—CH2—R4 (1) (In formula (1), R1 and R3 represent different perfluoropolyether chains, R2 represents a linking group containing one or more polar groups, and R4 represents a terminal group containing two or more polar groups.)
US11332685B2
A furniture lubricant for coating a linear lacquered furniture slide bar to provide a slide layer with lowered friction. The furniture lubricant comprises a C10 to C28 alkane and a tri-glyceride. The viscosity, according to ISO 3104:1994/COR 1:1997, of the furniture lubricant at 40° C. is 20 to 80 mm2/s.
US11332684B2
An octane-enhancing additive includes a mixed butanol composition, sec-butyl ether, methanol, methyl tert-butyl ether, and a C4-dimer, the mixed butanol composition comprising sec-butanol and tert-butanol, and the C4-dimer comprising di-isobutylene, 2,2,4 trimethylpentane, 2,3,3 trimethylpentane, or a combination comprising at least one of the foregoing.
US11332679B2
Naphthenic process oils are made by blending one or more naphthenic vacuum gas oils in one or more viscosity ranges with a high CA content ethylene cracker bottoms, slurry oil, heavy cycle oil or light cycle oil feedstock to provide at least one blended oil, and hydrotreating the at least one blended oil to provide an enhanced CA content naphthenic process oil. The order of the vacuum distillation and blending steps may be reversed.
US11332672B2
The present invention relates to a liquid crystal alignment agent composition comprising a polymerizable liquid crystal alignment polymer; and a catalyst precursor compound of a specific structure, a method for preparing a liquid crystal alignment film using the same, and a liquid crystal alignment film and a liquid crystal display using the same.
US11332668B2
A treated medium for plant growth includes (A) a medium for plant growth and (B) a water retaining composition disposed on the medium. The composition also includes (1) an alcohol alkoxylate, (2) water, (3) a surfactant, and (4) a humectant. The (1) alcohol alkoxylate has the structure: R-(EO)m—(PO)n-(EO)y—(PO)z—OH in which R is a C3-C14 linear or branched aliphatic carbon chain, EO is ethylene oxide, m is from 0 to 20, y is from 0 to 20, PO is propylene oxide, n is from 1 to 40, z is from 0 to 40, and (m+y) is at least 1. The (3) surfactant and (4) humectant are chosen from specific compounds. The treated medium has a water retention of from 100 to 400 grams of water per 100 grams of treated medium as compared to a control medium that is free of the water retaining composition.
US11332658B2
Formulations and methods for stimulating the production from wells in nano-darcy shale formations. In one embodiment, the method includes injecting a treatment mixture containing a metal complexing agent into a nano-darcy shale formation adjacent to a well at a pressure below the fracture pressure of the formation. A sufficient contact time is allowed and then the treatment mixture is pumped from the subsurface. This has been shown to stimulate well production in shale formations. Without being held to a particular theory it appears that the metal complexing agent is binding with naturally occurring metals in the shale formation, and particularly divalent metal ions, which are then extracted with the spent fluid. This removal of naturally occurring metals may be increasing the permeability of the formation in the contact region adjacent to the well, thereby causing the observed increased production.
US11332657B2
Dual cation hydrate inhibitor compositions and methods of using such compositions to, for example, inhibit the formation of gas hydrate agglomerates are provided. In some embodiments, such methods include introducing a hydrate inhibitor composition into a fluid, wherein the hydrate inhibitor composition includes at least one compound having the structural formula: wherein each of R1, R2, and R3 is independently a C1 to C6 hydrocarbon chain, wherein R4 is selected from the group consisting of hydrogen and any C1 to C50 hydrocarbon chain, wherein each of R5 and R6 is independently selected from the group consisting of hydrogen and a C1 to C50 hydrocarbon chain, wherein X− and Y− are counter anions, and wherein each of a and b is independently an integer from 1 to 10.
US11332646B2
The present invention relates to hot melt adhesive compositions comprising ethylene vinyl acetate copolymer(s) and isothiazolinone fungicides according to formula (I). Such hot melt adhesives show improved fungus resistance and are thus particularly suited for applications where such properties are desirable, such as ventilation and air-conditioning systems and air filters. The invention further relates to the use of said hot melt adhesives in such ventilation and air-conditioning systems and air filters as well as for bonding, stabilizing and sealing of pleats, edge and frame bonding, or seam sealing of bag filters. Further encompassed are air filters comprising the hot melt adhesives and methods of their manufacture using the hot melt adhesives of the invention.
US11332641B2
A polishing slurry composition enabling implementation of multi-selectivity is provided. The polishing slurry composition includes: a polishing liquid including abrasive particles; and an additive liquid, in which the additive liquid includes a polymer having an amide bond, and a cationic polymer.
US11332622B2
The present invention generally relates to a method for preparing a carbon black of high resistivity through the surface treatment of the carbon black which exhibits conductivity, and a carbon black prepared by this method.
US11332620B2
Solution comprising about 1 to about 25 wt % of a dye that loses its colour during radical cure and about 75 to about 99 wt % of a solvent mixture, said solvent mixture comprising cyclopentanone and dimethylsulphoxide in a weight ratio of about 60:40 to about 95:5.
US11332605B2
Disclosed is a thermoplastic elastomer composition having a superior low-temperature flexibility is provided. The thermoplastic elastomer composition may include an amount of about 10 to 15 wt % of a polypropylene-ethylene copolymer; an amount of about 70 to 85 wt % of a thermoplastic elastomer including an olefin-based thermoplastic elastomer and a styrene-based thermoplastic elastomer; an amount of about 5 to 10 wt % of a softener; an amount of about 3 to 5 wt % of a reinforcing agent; and an amount of about 1 wt % or less but greater than 0 wt % of a UV stabilizer based on the total weight of the thermoplastic elastomer composition.
US11332600B2
Disclosed is a method for producing nanocelluloses from a cellulose substrate including cellulose fibers, the method including the following sequence of steps: —a step of enzymatic treatment of the cellulose substrate, by bringing same into contact with at least one cleaving enzyme, then—a step of mechanical treatment of the cellulose substrate subjected to the step of enzymatic treatment, in order to delaminate the cellulose fibres and obtain the nanocelluloses. The at least one cleaving enzyme is chosen from the enzymes belonging to the family of lytic polysaccharide monooxygenases (LPMOs) capable of achieving cleavage in the presence of an electron donor. Also disclosed are the nanocelluloses obtained according to the method.
US11332599B2
There is provided a modified zirconium phosphate tungstate which effectively suppresses the elution of phosphorus ions even when it contacts with water, can develop the performance excellent as a negative thermal expansion material, and can be dispersed in a polymer compound such as a resin, and use of which enables a low-thermal expansive material containing a negative thermal expansion filler to be well produced. The surface of a zirconium phosphate tungstate particle is coated with an inorganic compound containing one or two or more elements (M) selected from Zn, Si, Al, Ba, Ca, Mg, Ti, V, Sn, Co, Fe and Zr. The BET specific surface area of the zirconium phosphate tungstate particle is preferably 0.1 m2/g to 50 m2/g.
US11332597B2
The present invention provides a photo-curable composition, and UV imprint method, that requires a small demolding force, wherein the photo-curable composition contains a polymerizable monomer (A), a polymerization initiator (B), and a fluorine-containing surfactant (C), and the photo-cured product of the photo-curable composition has a water contact angle of 74 degrees or less.
US11332587B2
A window for a display device and a display device including the window, the window including a base member; and a coating layer, the coating layer being formed on at least one surface of the base member and including core particles; and at least one polymer ligand, the polymer ligand being grafted onto surfaces of the core particles and bonds the core particles to the base member.
US11332585B2
A synthesis method includes synthesising copolydendrimers containing heteroatoms from at least two dendrimers as starting precursors.
US11332558B2
Provided is a water-absorbent resin that quickly absorbs water, even in sandbag in which a large amount of the water-absorbent resin has been used, that does not easily form unswollen lump, and that has a high gel swelling volume when water is used to swell the water-absorbent resin. This water-absorbent resin is configured from a polymer of water-soluble ethylenic unsaturated monomers. The physiological-saline absorption capacity of the water-absorbent resin is 40-60 g/g. When a cross-sectional image of the water-absorbent resin is observed by x-ray computed tomography, the fraction of the area of the cross-sectional image that is hollow portions (the hollow area ratio of the cross-sectional image), as calculated on the basis of formula (I), is no more than 10%. (I) Hollow area ratio [%]={total cross-sectional area (B) of hollow portions of the water-absorbent resin/(total cross-sectional area (A) of resin portions of the water-absorbent resin+total cross-sectional area (B) of hollow portions of the water-absorbent resin)}×100%.
US11332550B2
An apparatus for production of pulverulent polymers having a reactor for droplet polymerization with an apparatus for dropletization of a monomer solution for the preparation of the polymer. The apparatus for dropletization has holes through which the monomer solution is introduced, an addition point for a gas above the apparatus for dropletization, at least one gas withdrawal point at the periphery of the reactor and a fluidized bed, wherein at least one of the following is fulfilled: an apparatus for increasing turbulence in the gas flow is disposed in the region of the apparatus for dropletization of the monomer solution, an apparatus for increasing turbulence in the gas flow is disposed in the region of the addition point for the gas, the addition point for gas is configured such that elevated turbulence is generated. A process for producing pulverulent polymers, in which an increase in flow turbulence in the gas flow in the region of the apparatus for dropletization also is disclosed.
US11332548B2
A glycosaminoglycan derivative endowed with heparanase inhibitory activity and antitumor activity, bearing carboxylate groups in positions 2 and 3 of at least part of the glycosaminoglycan residues, and to the process for preparing the same. The glycosaminoglycan derivatives of the present invention are generated starting from natural or synthetic glycosaminoglycans, preferably heparin or low molecular weight heparin, optionally 2-O- and 2-N-desulfated by two steps of oxidation. By the first oxidation, adjacent dials and optionally adjacent OH/NH2 of the glycosaminoglycan residues are converted to aldehydes and by the second oxidation said dialdehydes are converted to carboxylate groups. The first oxidation preferably leads to the cleavage of C2-C3 linkage of the ring of oxidable residues. The invention relates to a process for the preparation of said glycosaminoglycan derivatives and to their use as active ingredients of medicaments.
US11332524B2
The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.
US11332521B2
The present disclosure provides antibodies that specifically bind to human FAM19A5 and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human FAM19A5 and modulate FAM19A5 activity, e.g., inhibit, suppress, reduce, or reverse the onset of reactive gliosis and/or excessive proliferation of reactive astrocytes, utilizing such antibodies. The present disclosure also provides methods for treating disorders, such as central nervous system damage, a degenerative brain disorder, or a neuropathic pain, by administering an antibody that specifically binds to human FAM19A5.
US11332517B2
The present invention relates to antibodies or antibody fragments that bind, neutralize, and/or inhibit Hendra or Nipah virus. The invention provides antibodies or antibody fragments that selectively bind to the F glycoprotein of Hendra or Nipah virus, and pharmaceutical compositions including such antibodies and/or fragments. The invention further provides polynucleotides encoding the antibodies and fragments of the invention and host cells transformed therewith. Additionally, the invention discloses prophylactic, therapeutic, and diagnostic methods employing the antibodies, fragments, polynucleotides, and/or compositions of the invention.
US11332515B2
The invention relates to multiple epitope constructs, immunogenic and vaccine compositions comprising recombinant molecules presenting inserted multiple and different epitopes from a variety of antigens. The antigenic determinants being associated with different pathways leading to atherosclerosis. In particular, the invention relates to such compositions for eliciting an immune response against antigens and pathogens involved in the development of atherosclerosis the invention includes inter alia methods of treating and/or preventing the disease and recombinant protein products.
US11332513B2
The present invention is directed to a chimeric antigen receptor (CAR) fusion protein comprising from N-terminus to C-terminus: (i) a single-chain variable fragment (scFv) comprising VH and VL, wherein scFv binds to a tumor antigen, (ii) a transmembrane domain, (iii) a co-stimulatory domain of GITR intracellular domain, and (iv) an activating domain. In one embodiment, the tumor antigen is human epidermal growth factor receptor (EGFR), human mesothelin, or human CD19. CARs having GITR intracellular domain as a co-stimulatory domain have certain advantages over other traditional CAR co-stimulatory domains.
US11332511B2
The present invention includes methods and compositions for treating cancer, whether a solid tumor or a hematologic malignancy. By expressing a chimeric antigen receptor in a monocyte, macrophage or dendritic cell, the modified cell is recruited to the tumor microenvironment where it acts as a potent immune effector by infiltrating the tumor and killing the target cells. One aspect includes a modified cell and pharmaceutical compositions comprising the modified cell for adoptive cell therapy and treating a disease or condition associated with immunosuppression.
US11332508B2
A a triple agonist having activities to all of glucagon, GLP-1, and GIP receptors is disclosed. Uses of the triple agonist are disclosed.
US11332507B2
The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
US11332501B2
New designed ankyrin repeat domains with binding specificity for serum albumin, recombinant binding proteins comprising at least two designed ankyrin repeat domains with binding specificity for serum albumin, as well as recombinant binding proteins comprising at least one designed ankyrin repeat domain with binding specificity for hepatocyte growth factor (HGF), at least one designed ankyrin repeat domain with binding specificity for vascular endothelial growth factor (VEGF-A), and at least two designed ankyrin repeat domain with binding specificity for serum albumin are described, as well as nucleic acids encoding such designed ankyrin repeat domains and recombinant binding proteins, pharmaceutical compositions comprising such designed ankyrin repeat domains, recombinant binding proteins or nucleic acids and the use of such designed ankyrin repeat domains, recombinant binding proteins, nucleic acids or pharmaceutical compositions in the treatment of diseases.
US11332495B2
Methods for preparing degarelix acetate are provided that include the steps of providing a suitable resin; deprotecting the resin with a diethylenetriamine solution; reacting sequentially the deprotected resin with different Fmoc protected amino acids; deprotecting the amino acid in each sequence with a diethylenetriamine solution in a stepwise fashion to yield a degarelix crude compound; and purifying the degarelix crude compound to yield pharmaceutically acceptable degarelix acetate. Methods of preparing degarelix acetate-mannitol premix and the resulting degarelix acetate-mannitol premix are also provided.