公开(公告)号：US12031962B2

公开(公告)日：2024-07-09

申请号：US16438797

申请日：2019-06-12

申请人： Roche Diagnostics Operations, Inc.

发明人： Dieter Heindl ,  Thomas Heinemeyer ,  Uwe Kobold ,  Martin Rempt ,  Christoph Seidel

IPC分类号： G01N30/46 ,  G01N30/02 ,  G01N30/06 ,  G01N30/28 ,  G01N30/72 ,  G01N33/58

CPC分类号： G01N30/466 ,  G01N30/06 ,  G01N30/28 ,  G01N30/7233 ,  G01N33/58 ,  G01N2030/027 ,  G01N2030/067

摘要： A method for identifying a reagent during a process in an analysis system is disclosed. The analysis system comprises a liquid chromatograph and a mass spectrometer. The method comprises providing a reagent, adding at least one chemical substance to the reagent with a concentration being above a detection level of the mass spectrometer, processing the reagent together with the chemical substance with the analysis system, and identifying the reagent based on a detection of a substance detection signal of the mass spectrometer representing the chemical substance.

公开(公告)号：US11774415B2

公开(公告)日：2023-10-03

申请号：US17212329

申请日：2021-03-25

申请人： Waters Technologies Corporation

发明人： Joshua A. Burnett ,  Rose Solow ,  David A. Simpson ,  Peter Osswald ,  John M. Auclair ,  Michael LeBeau

IPC分类号： G01N30/28 ,  G01N30/02 ,  G01N30/32

CPC分类号： G01N30/28 ,  G01N2030/027 ,  G01N2030/326 ,  G01N2030/328

摘要： Described is a metering pump that may be used to meter volumes of sample in a chromatography system. The metering pump has a modular configuration that allows for separation of a head pod from a drive assembly for easy serviceability. The head pod includes a pump head, cartridge housing, seal wash housing and plunger. The drive assembly can be implemented in an inline drive configuration. Alternatively, the drive assembly can be implemented in an offset drive configuration in which a stepper motor is displaced laterally from other drive assembly components but is coupled through a belt and pulley system.

公开(公告)号：US10338044B2

公开(公告)日：2019-07-02

申请号：US15142909

申请日：2016-04-29

申请人： Thermo Fisher Scientific (Bremen) GmbH

发明人： Johannes Schwieters ,  Michael Krummen ,  Hans-Juergen Schlueter ,  Oliver Kracht

IPC分类号： G01N30/28 ,  B01D53/02 ,  G01N33/00 ,  G01N30/06

摘要： A gas transport system includes at least one chemical reactor having at least one inlet and at least one gas outlet and at least one sample introduction unit for delivering the sample into the chemical reactor. The gas transport system at least one carrier gas line fluidly coupled to the chemical reactor inlet for introducing into the chemical reactor carrier gas from a carrier gas source, at least one gas outlet line from the chemical reactor gas outlet, and at least one gas recycling line connected to the gas outlet and/or the gas outlet line by a first gas line junction that is arranged between the chemical reactor and a downstream detection unit on the gas outlet line. The gas transport system is adapted to allow recycling of at least a portion of gas emerging from the chemical reactor outlet back to the chemical reactor via the gas recycling line.

公开(公告)号：US20180321198A1

公开(公告)日：2018-11-08

申请号：US15967752

申请日：2018-05-01

申请人： Waters Technologies Corporation

发明人： Abhijit Tarafder ,  Michael O. Fogwill ,  Joshua A. Shreve ,  Joseph D. Michienzi ,  Steven J. Ciavarini

IPC分类号： G01N30/28 ,  B01D15/10

CPC分类号： G01N30/28 ,  B01D15/10 ,  B01D15/16 ,  B01D15/40 ,  G01N30/32

摘要： The present disclosure relates generally to a system and a method for improving performance of a chromatography system using a highly-compressible fluid based mobile phase (e.g., CO2). In particular, the present disclosure relates to a system that uses a conduit, such as a convergent-divergent nozzle, for reducing pressure noise in a chromatography system using a highly-compressible fluid based mobile phase. The chromatography system can include a conduit, such as a convergent-divergent nozzle, disposed downstream of the column to reduce or prevent the propagation of pressure or density pulses from a back pressure regulator.

公开(公告)号：US09976998B2

公开(公告)日：2018-05-22

申请号：US14328926

申请日：2014-07-11

申请人： SHIMADZU CORPORATION

发明人： Hiroshi Ohashi

IPC分类号： G01N30/28 ,  G01N30/86 ,  G01N30/88 ,  B01D15/08 ,  B01D15/16 ,  G01N30/34 ,  G01N30/46

CPC分类号： G01N30/8658 ,  B01D15/08 ,  G01N30/34 ,  G01N30/466

摘要： Provided is a liquid chromatograph control system for controlling an operation of a liquid chromatograph according to a method file containing a plurality of analysis parameters representing configuration items which determine operational conditions of the liquid chromatograph, including: a) a display section for displaying, for each of the analysis parameters, selectable values of the analysis parameter on a condition-setting screen; b) a grouping section for allowing a user to prepare grouping information for the values of the analysis parameter displayed on the condition-setting screen, the grouping information determining whether or not one value of one analysis parameter and one value of another analysis parameter can be included in one group; and c) a file-creating section for extracting, from the values of the analysis parameters, such values that can be included in one group according to the grouping information, and for creating a method file containing the extracted values.

公开(公告)号：US09945821B2

公开(公告)日：2018-04-17

申请号：US14804846

申请日：2015-07-21

申请人： SGS North America Inc.

发明人： Wayne A. Kriel ,  Sven Lataire

IPC分类号： G01N1/16 ,  G01N30/28 ,  G01N1/24 ,  G01N1/22 ,  G01N30/06 ,  G01N33/22 ,  G01N30/02 ,  G01N1/10

CPC分类号： G01N30/28 ,  G01N1/22 ,  G01N1/2247 ,  G01N1/24 ,  G01N30/06 ,  G01N33/225 ,  G01N2001/105 ,  G01N2001/1093 ,  G01N2030/025

摘要： Composite sampling of a fluid flowing through a conduit includes collecting, in a vessel coupled to the conduit through which the fluid is flowing, a first discrete sample of fluid from the conduit, the first discrete sample having a first selected volume, and collecting, in the vessel and at a first interval from the first sample, a second discrete sample of the fluid from the conduit, the second discrete sample having a second selected volume, thereby forming a composite sample in the vessel while the vessel is coupled to conduit. The composite sample includes the first discrete sample and the second discrete sample, and may include one or more additional discrete samples. An apparatus for collecting the composite sample includes a gas chromatograph, and is arranged such that the composite sample is provided to the gas chromatograph without removing the composite sample from the apparatus or transporting the composite sample.

公开(公告)号：US09700813B2

公开(公告)日：2017-07-11

申请号：US14269336

申请日：2014-05-05

申请人： Tomas Hudlicky ,  Ian David Brindle ,  Mary Ann Endoma-Arias

发明人： Tomas Hudlicky ,  Ian David Brindle ,  Mary Ann Endoma-Arias

IPC分类号： B01D15/16 ,  B01D15/18 ,  G01N30/38 ,  G01N30/32 ,  B01D15/22 ,  G01N30/28 ,  B01D15/14

CPC分类号： B01D15/163 ,  B01D15/14 ,  B01D15/18 ,  G01N30/28 ,  G01N30/32 ,  G01N2030/324

摘要： The present disclosure relates to methods for the chromatographic separation of two or more sample components using a column while applying a time-pulsed pressure differential to the column and to apparatus for use in the same.

公开(公告)号：US09689859B2

公开(公告)日：2017-06-27

申请号：US14787521

申请日：2014-05-02

申请人： Dow Global Technologies LLC ,  Rohm and Haas Company

发明人： Ronda L. Gras ,  Jim C. Luong ,  Warren E. Smith

IPC分类号： G01N30/28 ,  G01N33/28 ,  C10L1/00 ,  G01N30/46 ,  G01N30/88 ,  G01N30/04

CPC分类号： G01N33/2882 ,  C10L1/003 ,  G01N30/468 ,  G01N2030/047 ,  G01N2030/8854

摘要： A gas chromatographic method for detecting a first marker and a second marker in a fuel in two channels: (i) a first capillary column coated with polysiloxane and a second capillary column coated with polyethylene glycol; and (ii) a third capillary column coated with polymethylphenylsiloxane and a fourth deactivated capillary column. The steps are: (a) introducing a first sample into the first column to produce a first effluent; (b) introducing only a portion of the first effluent into the second column to produce a second effluent; (c) allowing the second effluent to pass through a mass spectrometer; (d) introducing a second sample into the third column to produce a third effluent; (e) introducing only a portion of the third effluent into the fourth column to produce a fourth effluent; (f) allowing the fourth effluent to pass through a mass spectrometer.

公开(公告)号：US09465013B2

公开(公告)日：2016-10-11

申请号：US14223595

申请日：2014-03-24

申请人： Amber Lea Russell ,  Jennifer Maureen Seiter ,  Jessica Ann Coleman ,  Anthony Joseph Bednar

发明人： Amber Lea Russell ,  Jennifer Maureen Seiter ,  Jessica Ann Coleman ,  Anthony Joseph Bednar

IPC分类号： G01N30/28 ,  G01N33/22 ,  G01N30/02

CPC分类号： G01N30/28 ,  G01N30/88 ,  G01N33/227 ,  G01N2030/027 ,  G01N2030/884 ,  G01N30/74 ,  G01N21/33

摘要： HPLC methods for detecting, identifying and quantifying munitions compounds or munitions materials are disclosed. Insensitive munitions explosives (IMX) can be detected along with conventional munitions compounds such as 2,4,6-trinitrotolene (TNT) in a single column analysis. The methods are also useful to provide analytical evaluation of soil samples, aqueous samples such as ground water samples and tissue samples containing insensitive munitions explosives (IMX).

摘要翻译： 公开了用于检测，鉴定和量化弹药化合物或弹药材料的HPLC方法。 在单柱分析中可以与常规弹药化合物如2,4,6-三硝基苯乙烯（TNT）一起检测不敏感弹药爆炸物（IMX）。 这些方法还可用于提供土壤样品，含水样品如地下水样品和含有不敏感弹药爆炸物（IMX）的组织样品的分析评估。

公开(公告)号：US20150323508A1

公开(公告)日：2015-11-12

申请号：US14804846

申请日：2015-07-21

申请人： SGS North America Inc.

发明人： Wayne A. Kriel ,  Sven Lataire

IPC分类号： G01N30/28 ,  G01N1/24

CPC分类号： G01N30/28 ,  G01N1/22 ,  G01N1/2247 ,  G01N1/24 ,  G01N30/06 ,  G01N33/225 ,  G01N2001/105 ,  G01N2001/1093 ,  G01N2030/025

摘要： Composite sampling of a fluid flowing through a conduit includes collecting, in a vessel coupled to the conduit through which the fluid is flowing, a first discrete sample of fluid from the conduit, the first discrete sample having a first selected volume, and collecting, in the vessel and at a first interval from the first sample, a second discrete sample of the fluid from the conduit, the second discrete sample having a second selected volume, thereby forming a composite sample in the vessel while the vessel is coupled to conduit. The composite sample includes the first discrete sample and the second discrete sample, and may include one or more additional discrete samples. An apparatus for collecting the composite sample includes a gas chromatograph, and is arranged such that the composite sample is provided to the gas chromatograph without removing the composite sample from the apparatus or transporting the composite sample.

摘要翻译： 流经导管的流体的复合取样包括在与流体流过的导管相连的容器中收集来自导管的第一离散的流体样本，第一离散样品具有第一选定体积，并收​​集在 所述容器和来自所述第一样品的第一间隔，来自所述导管的所述流体的第二离散样品，所述第二离散样品具有第二选定体积，从而在所述容器联接到导管时在所述容器中形成复合样品。 复合样品包括第一离散样品和第二离散样品，并且可以包括一个或多个另外的离散样品。 用于收集复合样品的装置包括气相色谱仪，并且被布置成使得将复合样品提供到气相色谱仪，而不从装置中移除复合样品或输送复合样品。