Squarylium dye and filter for display device
    3.
    发明授权
    Squarylium dye and filter for display device 失效
    Squarylium染料和过滤器用于显示装置

    公开(公告)号:US06638624B2

    公开(公告)日:2003-10-28

    申请号:US09861714

    申请日:2001-05-22

    申请人: Tetsuo Ozawa

    发明人: Tetsuo Ozawa

    IPC分类号: C07D40302

    摘要: A filter for a display device, which comprises a dipyrazolylsquarylium dye represented by formula: wherein A and B each independently represent a substituted or unsubstituted pyrazolyl group. The filter is excellent in resistance to heat and light and gives no adverse influences on luminescence of the three primary colors, red, green and blue.

    摘要翻译: 一种用于显示装置的过滤器,其包含由下式表示的二吡唑并吡咯鎓染料:其中A和B各自独立地表示取代或未取代的吡唑基。 该滤光片的耐热性和耐光性优异,对红,绿,蓝三原色的发光没有不利影响。

    Integrin antagonists
    4.
    发明授权
    Integrin antagonists 有权
    整合素拮抗剂

    公开(公告)号:US06489333B2

    公开(公告)日:2002-12-03

    申请号:US09828751

    申请日:2001-04-09

    IPC分类号: C07D40302

    摘要: This invention relates to novel heterocycles which are useful as antagonists of the &agr;v&bgr;3 integrin, the &agr;2b&bgr;3 integrin, and related cell surface adhesive protein receptors, to pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using these compounds, alone or in combination with other therapeutic agents, for the inhibition of cell adhesion, the treatment of angiogenic disorders, inflammation, bone degradation, cancer metastasis, diabetic retinopathy, thrombosis, restenosis, macular degeneration, and other conditions mediated by cell adhesion and/or cell migration and/or angiogenesis.

    摘要翻译: 本发明涉及可用作α1bβ3整联蛋白,α2bβ3整联蛋白和相关细胞表面粘附蛋白受体的拮抗剂的新型杂环,含有这些化合物的药物组合物,制备此类化合物的方法,以及单独使用这些化合物的方法 或与其他治疗剂组合用于抑制细胞粘附,血管生成障碍,炎症,骨退化,癌转移,糖尿病性视网膜病变,血栓形成,再狭窄,黄斑变性以及由细胞粘附和/或细胞介导的其它病症的治疗 迁移和/或血管发生。

    4-and 5-alkynyloxindoles and 4-and 5-alkenyloxindoles
    9.
    发明授权
    4-and 5-alkynyloxindoles and 4-and 5-alkenyloxindoles 失效
    4-和5-炔氧基吲哚和4-和5-烯氧基吲哚

    公开(公告)号:US06313310B1

    公开(公告)日:2001-11-06

    申请号:US09464238

    申请日:1999-12-15

    IPC分类号: C07D40302

    摘要: Disclosed are 4- and 5-alkynyloxindoles as well as 4- and 5-alkenyloxindoles that inhibit or modulate protein kinases, in particular JNK protein kinases. The compounds of the invention and their pharmaceutically acceptable salts, and prodrugs of said compounds, are useful as anti-inflammatory agents, particularly useful in the treatment of rheumatoid arthritis. Also disclosed are pharmaceutical compositions containing the foregoing compounds, methods for the treatment and/or control of inflammation, particularly in the treatment or control of rheumatoid arthritis using these compounds, as well as intermediates useful in the preparation of compounds of the invention.

    摘要翻译: 公开了抑制或调节蛋白激酶,特别是JNK蛋白激酶的4-和5-炔氧基吲哚以及4-和5-链烯氧基吲哚。 本发明的化合物及其药学上可接受的盐和所述化合物的前药可用作抗炎剂,特别可用于治疗类风湿性关节炎。 还公开了含有前述化合物的药物组合物,用于治疗和/或控制炎症的方法,特别是在使用这些化合物治疗或控制类风湿性关节炎的药物组合物中,以及可用于制备本发明化合物的中间体。