公开(公告)号：US20190198781A1

公开(公告)日：2019-06-27

申请号：US15854716

申请日：2017-12-26

Applicant: Feng-Wen YEN ,  Chin-Min TENG

Inventor： Feng-Wen YEN ,  Chin-Min TENG

IPC: H01L51/00 ,  H01L51/50 ,  C07C13/62 ,  C07D209/82 ,  C07D307/91 ,  C07D333/76 ,  C07F7/08 ,  C09K11/06

Abstract: An organic compound which can be used as the phosphorescent host material, the fluorescent host material, or the fluorescent dopant material of the light emitting layer, and/or the electron transporting material in the organic electroluminescence device is disclosed. The organic electroluminescence device employing the organic compound can lower driving voltage, prolong half-lifetime, and increase current efficiency.

公开(公告)号：US20180182975A1

公开(公告)日：2018-06-28

申请号：US15390720

申请日：2016-12-27

Applicant: FENG-WEN YEN ,  Wen-Feng Hsiao ,  Chin-Min Teng

Inventor： FENG-WEN YEN ,  Wen-Feng Hsiao ,  Chin-Min Teng

IPC: H01L51/00 ,  C09K11/06 ,  C09K11/02 ,  C07D417/14

CPC classification number: H01L51/0071 ,  C07D417/14 ,  C09K11/02 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1029 ,  C09K2211/1051 ,  C09K2211/185 ,  H01L51/0072 ,  H01L51/0085 ,  H01L51/5016 ,  H01L51/5072 ,  H01L51/5096 ,  H01L2251/5361

Abstract: The present invention discloses a delayed fluorescence compound and the organic EL device employing the delayed fluorescence compound as light emitting host of emitting lay and/or an electron transporting layer, and/or a hole blocking layer, and/or a delayed fluorescence material of emitting layer for organic EL device in the present invention display good performance.

公开(公告)号：US20120202809A1

公开(公告)日：2012-08-09

申请号：US13450388

申请日：2012-04-18

Applicant: Hui Li ,  Seiji Nukui ,  Stephanie Anne Scales ,  Min Teng ,  Chunfeng Yin

Inventor： Hui Li ,  Seiji Nukui ,  Stephanie Anne Scales ,  Min Teng ,  Chunfeng Yin

IPC: A61K31/5377 ,  A61K31/506 ,  A61K31/4985 ,  A61K31/4545 ,  A61K31/496 ,  A61P3/10 ,  A61P35/00 ,  A61P9/10 ,  A61P29/00 ,  A61P25/00 ,  A61P9/00 ,  A61P25/28 ,  A61P17/00 ,  A61P31/12 ,  A61P1/16 ,  A61P13/12 ,  A61P27/02 ,  C07D487/04

CPC classification number: C07D519/00 ,  C07D487/04

Abstract: The present invention relates to compounds and pharmaceutically acceptable salts of Formulas A and B: wherein A, B, R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined above. The invention further relates to pharmaceutical compositions comprising the compounds and pharmaceutically acceptable salts and to methods of treating diabetes mellitus and its complications, cancer, ischemia, inflammation, central nervous system disorders, cardiovascular disease, Alzheimer's disease and dermatological disase pression, virus diseases, inflammatory disorders, or diseases in which the liver is a target organ.

Abstract translation: 本发明涉及式A和B的化合物和药学上可接受的盐：其中A，B，R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8，R 9和R 10如上所定义。 本发明还涉及包含该化合物和药学上可接受的盐的药物组合物以及治疗糖尿病及其并发症，癌症，局部缺血，炎症，中枢神经系统疾病，心血管疾病，阿尔茨海默氏病和皮肤病学抑制的病毒病，炎性疾病 疾病或肝脏是靶器官的疾病。

公开(公告)号：US20070135415A1

公开(公告)日：2007-06-14

申请号：US11426132

申请日：2006-06-23

Applicant: Suzanne Benedict ,  Michael Bennett ,  Sacha Ninkovic ,  Min Teng ,  Eugene Rui ,  Fen Wang ,  Yong Wang ,  Jinjiang Zhu

Inventor： Suzanne Benedict ,  Michael Bennett ,  Sacha Ninkovic ,  Min Teng ,  Eugene Rui ,  Fen Wang ,  Yong Wang ,  Jinjiang Zhu

IPC: A61K31/551 ,  C07D487/02

CPC classification number: C07D487/06 ,  C07D498/06

Abstract: Protein kinase, such as CHK-1, inhibiting tricyclic compounds of the following formula (wherein R2, R3 and R4 are as defined in the specification) pharmaceutical compositions containing effective amounts of said compounds or their salts are useful as a single agent or in combination with an anti-neoplastic agent or therapeutic radiation having an anti-neoplastic effect for treating diseases or conditions such as cancers. The current invention relates to the making and using of such compounds.

Abstract translation: 蛋白激酶，如CHK-1，抑制下式（其中R 2，R 3，R 3和R 4）的三环化合物如上定义 在本说明书中）含有有效量的所述化合物或其盐的药物组合物可用作单一试剂或与用于治疗疾病或病症如癌症的抗肿瘤作用的抗肿瘤剂或治疗辐射组合。 本发明涉及制备和使用这些化合物。

公开(公告)号：US20060004052A1

公开(公告)日：2006-01-05

申请号：US11187089

申请日：2005-07-22

Applicant: Suzanne Benedict ,  Michael Bennett ,  Sacha Ninkovic ,  Min Teng ,  Eugene Rui ,  Fen Wang ,  Yong Wang ,  Zinjiang Zhu

Inventor： Suzanne Benedict ,  Michael Bennett ,  Sacha Ninkovic ,  Min Teng ,  Eugene Rui ,  Fen Wang ,  Yong Wang ,  Zinjiang Zhu

IPC: A61K31/454 ,  C07D487/02

CPC classification number: C07D487/06 ,  C07D498/06

Abstract: Protein kinase, such as CHK-1, inhibiting tricyclic compounds of the following formula (wherein R2, R3and R4 are as defined in the specification) pharmaceutical compositions containing effective amounts of said compounds or their salts are useful as a single agent or in combination with an anti-neoplastic agent or therapeutic radiation having an anti-neoplastic effect for treating diseases or conditions such as cancers.

Abstract translation: 蛋白激酶，如CHK-1，抑制下式（其中R 2，R 3，R 3和R 4）的三环化合物如上定义 在本说明书中）含有有效量的所述化合物或其盐的药物组合物可用作单一试剂或与用于治疗疾病或病症如癌症的抗肿瘤作用的抗肿瘤剂或治疗辐射组合。

公开(公告)号：US06967198B2

公开(公告)日：2005-11-22

申请号：US10754171

申请日：2004-01-09

Applicant: Suzanne Benedict ,  Michael Bennett ,  Sacha Ninkovic ,  Min Teng ,  Yuanjin Rui ,  Fen Wang ,  Yong Wang ,  Jinjiang Zhu

Inventor： Suzanne Benedict ,  Michael Bennett ,  Sacha Ninkovic ,  Min Teng ,  Yuanjin Rui ,  Fen Wang ,  Yong Wang ,  Jinjiang Zhu

IPC: A61K31/55 ,  A61P35/00 ,  C07D487/06 ,  C07D498/06 ,  A61K31/551 ,  C07D487/02

CPC classification number: C07D487/06 ,  C07D498/06

Abstract: Protein kinase, such as CHK-1, inhibiting tricyclic compounds of the following formula (wherein R2, R3 and R4 are as defined in the specification) pharmaceutical compositions containing effective amounts of said compounds or their salts are useful as a single agent or in combination with an anti-neoplastic agent or therapeutic radiation having an anti-neoplastic effect for treating diseases or conditions such as cancers.

Abstract translation: 蛋白激酶，如CHK-1，抑制下式（其中R 2，R 3，R 3和R 4）的三环化合物如上定义 在本说明书中）含有有效量的所述化合物或其盐的药物组合物可用作单一试剂或与用于治疗疾病或病症如癌症的抗肿瘤作用的抗肿瘤剂或治疗辐射组合。

公开(公告)号：US06891044B2

公开(公告)日：2005-05-10

申请号：US10326037

申请日：2003-02-15

Applicant: Robert Steven Kania ,  Steven Lee Bender ,  Allen J. Borchardt ,  Stephan James Cripps ,  Ye Hua ,  Michael David Johnson ,  Theodore Otto Johnson, Jr. ,  Hiep The Luu ,  Cynthia Louise Palmer ,  Siegfried Heinz Reich ,  Anna Maria Tempczyk-Russell ,  Min Teng ,  Christine Thomas ,  Michael David Varney ,  Michael Brennan Wallace ,  Michael Raymond Collins

Inventor： Robert Steven Kania ,  Steven Lee Bender ,  Allen J. Borchardt ,  Stephan James Cripps ,  Ye Hua ,  Michael David Johnson ,  Theodore Otto Johnson, Jr. ,  Hiep The Luu ,  Cynthia Louise Palmer ,  Siegfried Heinz Reich ,  Anna Maria Tempczyk-Russell ,  Min Teng ,  Christine Thomas ,  Michael David Varney ,  Michael Brennan Wallace ,  Michael Raymond Collins

IPC: C07D209/18 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D401/02

CPC classification number: C07D401/12 ,  C07D209/18 ,  C07D401/14 ,  C07D403/12

Abstract: Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer and other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.

Abstract translation: 描述了调节和/或抑制某些蛋白激酶活性的吲唑化合物。 这些化合物和含有它们的药物组合物能够介导酪氨酸激酶信号转导，从而调节和/或抑制不期望的细胞增殖。 本发明还涉及含有这些化合物的药物组合物的治疗或预防用途，以及治疗与不需要的血管生成和/或细胞增殖相关的癌症和其它疾病状态的方法，例如糖尿病性视网膜病变，新生血管性青光眼，类风湿性关节炎和 银屑病，通过施用有效量的这种化合物。

公开(公告)号：US06818775B2

公开(公告)日：2004-11-16

申请号：US10731448

申请日：2003-12-09

Applicant: Alan T. Johnson ,  Min Teng ,  Vidyasagar Vuligonda ,  Richard L. Beard ,  Samuel J. Gillett ,  Tien T. Duong ,  Roshantha A. Chandraratna

Inventor： Alan T. Johnson ,  Min Teng ,  Vidyasagar Vuligonda ,  Richard L. Beard ,  Samuel J. Gillett ,  Tien T. Duong ,  Roshantha A. Chandraratna

IPC: C07D1172

CPC classification number: C07D317/24 ,  C07C69/587 ,  C07C69/76 ,  C07C233/81 ,  C07C245/10 ,  C07C251/44 ,  C07C309/65 ,  C07C317/44 ,  C07C323/55 ,  C07C2602/10 ,  C07D277/30 ,  C07D309/12 ,  C07D317/20 ,  C07D317/26 ,  C07D333/24 ,  C07D339/08 ,  C07D409/10

Abstract: Compounds of the formula where the symbols have the meaning described in the application, have retinoid-like or retinoid antagonist-like biological activity.

Abstract translation: 符号具有本申请中描述的含义的化合物具有类视黄醇样或类视黄醇拮抗剂样的生物活性。

公开(公告)号：US06653483B1

公开(公告)日：2003-11-25

申请号：US09550952

申请日：2000-04-17

Applicant: Alan T. Johnson ,  Min Teng ,  Vidyasagar Vuligonda ,  Richard L. Beard ,  Samuel J. Gillett ,  Tien T. Duong ,  Roshantha A. Chandraratna

Inventor： Alan T. Johnson ,  Min Teng ,  Vidyasagar Vuligonda ,  Richard L. Beard ,  Samuel J. Gillett ,  Tien T. Duong ,  Roshantha A. Chandraratna

IPC: C07D21372

CPC classification number: C07D409/10 ,  C07C69/587 ,  C07C69/76 ,  C07C233/81 ,  C07C245/10 ,  C07C251/44 ,  C07C309/65 ,  C07C317/44 ,  C07C323/55 ,  C07C2602/10 ,  C07D277/30 ,  C07D309/12 ,  C07D317/20 ,  C07D317/24 ,  C07D317/26 ,  C07D333/24 ,  C07D339/08

Abstract: Compounds of the formula where the symbols have the meaning described in the application, have retinoid-like or retinoid antagonist-like biological activity.

公开(公告)号：US06245786B1

公开(公告)日：2001-06-12

申请号：US09550744

申请日：2000-04-17

Applicant: Min Teng ,  Tien T. Duong ,  Roshantha A. Chandraratna

Inventor： Min Teng ,  Tien T. Duong ,  Roshantha A. Chandraratna

IPC: C07D21302

CPC classification number: C07D213/82 ,  C07C233/81

Abstract: Compounds of the formula wherein the symbols have the meaning described in the specification, have retinoid-like biological activity.

Abstract translation: 符号表示的化合物具有说明书中描述的含义，具有类视黄醇样生物活性。