发明授权
- 专利标题： Aromatic sulfonyl alpha-hydroxy hydroxamic acid compounds
- 专利标题（中）： 芳香磺酰基α-羟基异羟肟酸化合物
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申请号： US09254535申请日： 1999-06-04
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公开(公告)号： US06362183B1公开(公告)日： 2002-03-26
- 发明人: John N. Freskos , Terri L. Boehm , Brent V. Mischke , Robert M. Heintz , Joseph J. McDonald , Gary A. DeCrescenzo , Susan C. Howard
- 申请人： John N. Freskos , Terri L. Boehm , Brent V. Mischke , Robert M. Heintz , Joseph J. McDonald , Gary A. DeCrescenzo , Susan C. Howard
- 主分类号： C07D40302
- IPC分类号： C07D40302
摘要：
An aromatic sulfonyl alpha-hydroxy hydroxamic acid compound that, inter alia, inhibits matrix metalloprotease activity is disclosed, as is a treatment process that comprises administering a contemplated aromatic sulfonyl alpha-hydroxy hydroxamic acid compound in an MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity.
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