-
公开(公告)号:US11773423B2
公开(公告)日:2023-10-03
申请号:US15753378
申请日:2016-08-17
申请人: ZuChem, Inc.
IPC分类号: C12P19/60 , C12P19/18 , C12N9/12 , C12N9/88 , A61K35/66 , C12N9/90 , C12N9/10 , C12N9/04 , A61K35/00
CPC分类号: C12P19/60 , A61K35/66 , C12N9/0006 , C12N9/1029 , C12N9/1096 , C12N9/1241 , C12N9/88 , C12N9/90 , C12P19/18 , C12Y101/01049 , C12Y206/01 , C12Y207/07024 , C12Y402/01046 , C12Y501/03013 , A61K35/00 , Y02A50/30
摘要: The invention provides compositions and methods for the production of TDP-deoxysugars.
-
公开(公告)号:US20230227879A1
公开(公告)日:2023-07-20
申请号:US17769001
申请日:2020-10-02
CPC分类号: C12P19/26 , C12N15/52 , C12N15/76 , C12N9/1241 , C12N9/88 , C12Y207/07009 , C12Y402/01046 , C12R2001/045
摘要: The present invention relates to Actinomycetales strains for the improved formation of acarbose. Provided are Actinomycetales strains which are engineered to overexpress dTDP-D-glucose-4,6-dehydratase (AcbB) and/or uridyltransferase (GtaB). Also provided are Actinomycetales strains which are engineered to have a reduced or absent expression of the small carbohydrate binding protein (Cgt) and/or a reduced or absent expression of genes which are essential for carotenoid synthesis. Also provided are tools, methods and means to generate these strains.
-
公开(公告)号:US20240110216A1
公开(公告)日:2024-04-04
申请号:US18329744
申请日:2023-06-06
申请人: ZuChem, Inc.
CPC分类号: C12P19/60 , A61K35/66 , C12N9/0006 , C12N9/1029 , C12N9/1096 , C12N9/1241 , C12N9/88 , C12N9/90 , C12P19/18 , C12Y101/01049 , C12Y206/01 , C12Y207/07024 , C12Y402/01046 , C12Y501/03013 , A61K35/00
摘要: The invention provides compositions and methods for the production of TDP-deoxysugars.
-
公开(公告)号:US20180245118A1
公开(公告)日:2018-08-30
申请号:US15753378
申请日:2016-08-17
申请人: ZuChem, Inc.
CPC分类号: C12P19/60 , A61K35/00 , A61K35/66 , C12N9/0006 , C12N9/1029 , C12N9/1096 , C12N9/1241 , C12N9/88 , C12N9/90 , C12P19/18 , C12Y101/01049 , C12Y206/01 , C12Y207/07024 , C12Y402/01046 , C12Y501/03013 , Y02A50/473
摘要: The invention provides compositions and methods for the production of TDP-deoxysugars.
-
-
-