公开(公告)号：US20240110216A1

公开(公告)日：2024-04-04

申请号：US18329744

申请日：2023-06-06

申请人： ZuChem, Inc.

发明人： Micah Douglas Shepherd

IPC分类号： C12P19/60 ,  A61K35/66 ,  C12N9/04 ,  C12N9/10 ,  C12N9/12 ,  C12N9/88 ,  C12N9/90 ,  C12P19/18

CPC分类号： C12P19/60 ,  A61K35/66 ,  C12N9/0006 ,  C12N9/1029 ,  C12N9/1096 ,  C12N9/1241 ,  C12N9/88 ,  C12N9/90 ,  C12P19/18 ,  C12Y101/01049 ,  C12Y206/01 ,  C12Y207/07024 ,  C12Y402/01046 ,  C12Y501/03013 ,  A61K35/00

摘要： The invention provides compositions and methods for the production of TDP-deoxysugars.

公开(公告)号：US20180245118A1

公开(公告)日：2018-08-30

申请号：US15753378

申请日：2016-08-17

申请人： ZuChem, Inc.

发明人： Micah Douglas Shepherd

IPC分类号： C12P19/60 ,  C12N9/12 ,  C12N9/88 ,  C12P19/18

CPC分类号： C12P19/60 ,  A61K35/00 ,  A61K35/66 ,  C12N9/0006 ,  C12N9/1029 ,  C12N9/1096 ,  C12N9/1241 ,  C12N9/88 ,  C12N9/90 ,  C12P19/18 ,  C12Y101/01049 ,  C12Y206/01 ,  C12Y207/07024 ,  C12Y402/01046 ,  C12Y501/03013 ,  Y02A50/473

摘要： The invention provides compositions and methods for the production of TDP-deoxysugars.

公开(公告)号：US20210189440A1

公开(公告)日：2021-06-24

申请号：US17116704

申请日：2020-12-09

申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS ,  ZUCHEM INC.

发明人： Huimin Zhao ,  Nikhil Unni Nair ,  Michael Racine ,  Ryan Woodyer

IPC分类号： C12P7/18

摘要： Materials and methods are described to produce xylitol from a mixture of hemicellulosic sugars by several routes. Examples include either as a direct co-product of a biorefinery or ethanol facility, or as a stand-alone product produced from an agricultural or forestry biomass feedstock including using, e.g. ethanol waste streams.

公开(公告)号：US20160272953A1

公开(公告)日：2016-09-22

申请号：US15172836

申请日：2016-06-03

申请人： ZuChem, Inc.

发明人： Ryan Woodyer ,  Paul Taylor ,  David Demirjian

IPC分类号： C12N9/12 ,  C12P19/02 ,  C12P19/18

CPC分类号： C12N9/1241 ,  C12N9/1205 ,  C12P19/02 ,  C12P19/18 ,  C12P19/38 ,  C12Y207/07

摘要： Kinase and nucleotidyltransferase enzymes for the production of activated sugars have been developed. These enzymes have improved stability for industrial application and relaxed specificity towards a variety of sugars. These enzymes are useful in, for example, the production of diverse NDP-sugars for glycosylation of aglycones of interest, production of oligosaccharides, production of other important glycoylated sugars, and in drug discovery applications.

摘要翻译： 已经开发了用于生产活性糖的激酶和核苷酸转移酶。 这些酶具有改善的工业应用稳定性和对各种糖的放宽特异性。 这些酶可用于例如生产用于目标糖苷配基糖基化的多种NDP-糖，寡糖的产生，其它重要的糖基化糖的生产以及药物发现应用中。

公开(公告)号：US11773423B2

公开(公告)日：2023-10-03

申请号：US15753378

申请日：2016-08-17

申请人： ZuChem, Inc.

发明人： Micah Douglas Shepherd

IPC分类号： C12P19/60 ,  C12P19/18 ,  C12N9/12 ,  C12N9/88 ,  A61K35/66 ,  C12N9/90 ,  C12N9/10 ,  C12N9/04 ,  A61K35/00

CPC分类号： C12P19/60 ,  A61K35/66 ,  C12N9/0006 ,  C12N9/1029 ,  C12N9/1096 ,  C12N9/1241 ,  C12N9/88 ,  C12N9/90 ,  C12P19/18 ,  C12Y101/01049 ,  C12Y206/01 ,  C12Y207/07024 ,  C12Y402/01046 ,  C12Y501/03013 ,  A61K35/00 ,  Y02A50/30

摘要： The invention provides compositions and methods for the production of TDP-deoxysugars.

公开(公告)号：US20190106720A1

公开(公告)日：2019-04-11

申请号：US16167207

申请日：2018-10-22

申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS ,  ZUCHEM INC.

发明人： Huimin Zhao ,  Nikhil Unni Nair ,  Michael Racine ,  Ryan Woodyer

IPC分类号： C12P7/18

摘要： Materials and methods are described to produce xylitol from a mixture of hemicellulosic sugars by several routes. Examples include either as a direct co-product of a biorefinery or ethanol facility, or as a stand-alone product produced from an agricultural or forestry biomass feedstock including using, e.g. ethanol waste streams.

公开(公告)号：US20180194794A1

公开(公告)日：2018-07-12

申请号：US15736126

申请日：2016-06-15

申请人： zuChem, Inc.

发明人： Leila Aminova

IPC分类号： C07H19/10 ,  C07H1/08 ,  C07H3/06 ,  C12P19/18 ,  C12N9/10 ,  C12N9/12 ,  C12N9/90

CPC分类号： C07H19/10 ,  C07H1/08 ,  C07H3/06 ,  C12N9/1048 ,  C12N9/1241 ,  C12N9/90 ,  C12P19/18 ,  C12Y207/07012

摘要： The invention relates to production of uridine-5′diphospho-N-acetylglucosamine and uridine-5′diphospho-N-acetylgalactosamine. The invention further relates to the production of lacto-/V-triose II and globotetraose.