公开(公告)号：US20170362557A1

公开(公告)日：2017-12-21

申请号：US15536584

申请日：2015-12-15

申请人： NOVELLUSDX LTD.

发明人： Yehoshua SHEINMAN ,  Revital SHARIVKIN ,  Merav BELENKOVICH

IPC分类号： C12M1/32 ,  C12M1/18 ,  C40B60/08 ,  C12M3/00 ,  C12M1/26

CPC分类号： C12M33/06 ,  B01J2219/00351 ,  B01J2219/00369 ,  B01J2219/00619 ,  B01J2219/00621 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00734 ,  B01J2219/00743 ,  C12M1/18 ,  C12M3/00 ,  C12M33/14 ,  C40B60/08

摘要： The present disclosure provides systems, devices and methods for seeding cells or sets of molecules on a substrate by utilizing a seeding mesh, to obtain an essentially homogenous patterned seeding of the cells or sets of molecules on the mesh.

公开(公告)号：US20130174287A1

公开(公告)日：2013-07-04

申请号：US13808399

申请日：2011-07-06

申请人： Gustavo Andres Higuera ,  Lorenzo Moroni ,  Clemens Antoni van Blitterswijk

发明人： Gustavo Andres Higuera ,  Lorenzo Moroni ,  Clemens Antoni van Blitterswijk

IPC分类号： C12M1/18

CPC分类号： C12M1/18 ,  B01L3/5085 ,  B01L2300/0829 ,  B01L2300/163 ,  C12M21/08 ,  C12M23/12 ,  C12M23/20

摘要： The invention relates to a multiwell system, characterized that said multiwell system having at least 3 wells, wherein said wells have a volume between 0.125 and 4.0 mm3.

摘要翻译： 本发明涉及一种多井系统，其特征在于所述多井系统具有至少3个井，其中所述井的体积在0.125和4.0mm 3之间。

公开(公告)号：US11680234B2

公开(公告)日：2023-06-20

申请号：US17314098

申请日：2021-05-07

申请人： BECTON DICKINSON AND COMPANY

发明人： Ryan D. Crandall

IPC分类号： C12M1/18 ,  C12M1/00 ,  C12M3/00 ,  C12Q1/02 ,  C12M1/22 ,  C12M1/12

CPC分类号： C12M1/18 ,  C12M23/02 ,  C12M23/04 ,  C12M23/10 ,  C12M23/26 ,  C12M23/28 ,  C12M23/38 ,  C12M23/44 ,  C12M23/46 ,  C12Q1/02

摘要： The present invention relates to systems and methods involving interconnected plate components, including bases, lids and covers, interconnected in a manner such that a continuous strip of each component is prepared. The continuous strips may be stored as rollstock in a reel style. The physical properties of each continuous strip allow the base, lid and/or cover to include means for positive control. In one embodiment, the continuous strip of bases is advanced and processed through an automated system with positive control, and remains in the form of a continuous strip until agar in the bases is cured, at which time the bases are singulated. When a lid is applied to a base using methods described herein, an airtight seal is formed improving the quality of culture media used in testing.

公开(公告)号：US09133429B2

公开(公告)日：2015-09-15

申请号：US13808399

申请日：2011-07-06

申请人： Gustavo Andres Higuera ,  Lorenzo Moroni ,  Clemens Antoni van Blitterswijk

发明人： Gustavo Andres Higuera ,  Lorenzo Moroni ,  Clemens Antoni van Blitterswijk

IPC分类号： C12N5/00 ,  C12M1/12 ,  C12M1/18 ,  B01L3/00 ,  C12M3/00 ,  C12M1/32 ,  C12M1/00

CPC分类号： C12M1/18 ,  B01L3/5085 ,  B01L2300/0829 ,  B01L2300/163 ,  C12M21/08 ,  C12M23/12 ,  C12M23/20

摘要： The invention relates to a multiwell system, characterized that said multiwell system having at least 3 wells, wherein said wells have a volume between 0.125 and 4.0 mm3.

摘要翻译： 本发明涉及一种多井系统，其特征在于所述多井系统具有至少3个井，其中所述井的体积在0.125和4.0mm 3之间。

公开(公告)号：US20230392178A1

公开(公告)日：2023-12-07

申请号：US18449087

申请日：2023-08-14

申请人： International Business Machines Corporation

发明人： Amos Cahan ,  Guy M. Cohen ,  Theodore G. van Kessel ,  Sufi Zafar

IPC分类号： C12Q1/02 ,  C12Q1/18 ,  G01N21/59 ,  G01N27/04 ,  G01N15/06 ,  C12M1/12 ,  C12M1/34 ,  C12M1/00 ,  C12M3/00 ,  C12M1/18

CPC分类号： C12Q1/02 ,  C12Q1/18 ,  G01N21/59 ,  G01N27/04 ,  G01N15/0656 ,  C12M25/14 ,  C12M41/36 ,  C12M1/3453 ,  C12M23/34 ,  C12M3/00 ,  C12M1/18 ,  C12M31/02 ,  G01N2201/08 ,  C12N2533/76 ,  G01N27/02

摘要： A structure for culturing cells includes growth medium regions on a surface of the structure. Each of the growth medium regions includes a growth medium surface configured to receive and promote growth in a cell that is being cultured. The structure includes a non-growth medium. The non-growth medium includes a non-growth medium surface configured to receive the cell that is being cultured.

公开(公告)号：US11781166B2

公开(公告)日：2023-10-10

申请号：US17708387

申请日：2022-03-30

申请人： International Business Machines Corporation

发明人： Amos Cahan ,  Guy M. Cohen ,  Theodore G. van Kessel ,  Sufi Zafar

IPC分类号： G01N27/02 ,  C12Q1/02 ,  C12Q1/18 ,  G01N21/59 ,  G01N27/04 ,  G01N15/06 ,  C12M1/12 ,  C12M1/34 ,  C12M1/00 ,  C12M3/00 ,  C12M1/18

CPC分类号： C12Q1/02 ,  C12M1/18 ,  C12M1/3453 ,  C12M3/00 ,  C12M23/34 ,  C12M25/14 ,  C12M31/02 ,  C12M41/36 ,  C12Q1/18 ,  G01N15/0656 ,  G01N21/59 ,  G01N27/04 ,  C12N2533/76 ,  G01N27/02 ,  G01N2201/08

摘要： A structure for culturing cells includes growth medium regions on a surface of the structure. Each of the growth medium regions includes a growth medium surface configured to receive and promote growth in a cell that is being cultured. The structure includes a non-growth medium. The non-growth medium includes a non-growth medium surface configured to receive the cell that is being cultured.

公开(公告)号：US09828576B2

公开(公告)日：2017-11-28

申请号：US14416330

申请日：2013-07-29

申请人： National University of Singapore ,  Centre National de la Recherche Scientifique

发明人： Virgile Nicolas Robert Viasnoff ,  Qiushi Li

IPC分类号： C12N1/12 ,  G01N33/50 ,  C12M1/12 ,  C12M1/18 ,  C12N5/00 ,  C12M1/32 ,  C12M1/00 ,  B01L3/00

CPC分类号： C12M25/04 ,  B01L3/5085 ,  C12M1/18 ,  C12M23/12 ,  C12M23/20 ,  C12M25/02 ,  C12N5/0062 ,  C12N5/0068 ,  C12N2529/10 ,  C12N2533/30 ,  C12N2533/52 ,  C12N2533/90 ,  C12N2537/10 ,  C12N2539/00 ,  G01N33/5014

摘要： The disclosure relates to the fabrication of a three dimensional [3-D] cell culture membrane comprising one or more functionalized surfaces adapted to provide cell culture conditions suitable for the analysis of proliferation, differentiation or function of cells, typically eukaryotic or prokaryotic cells.

公开(公告)号：US09599604B2

公开(公告)日：2017-03-21

申请号：US14281186

申请日：2012-12-07

申请人： University of Florida Research Foundation, Incorporated

发明人： Peter S. McFetridge

IPC分类号： C12M1/00 ,  G01N33/50 ,  C12M1/12 ,  C12M3/00 ,  C12M1/18 ,  C12M1/34 ,  C12M3/06

CPC分类号： G01N33/5005 ,  C12M1/18 ,  C12M1/34 ,  C12M23/16 ,  C12M23/22 ,  C12M23/34 ,  C12M23/42 ,  C12M23/46 ,  C12M25/00 ,  C12M25/02 ,  C12M25/04 ,  C12M25/14 ,  C12M29/10 ,  C12M41/36 ,  Y10T137/8359

摘要： In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to a device (or “flow chamber”), methods of making a device, methods of using a device, and the like.

公开(公告)号：US20150203809A1

公开(公告)日：2015-07-23

申请号：US14416330

申请日：2013-07-29

申请人： National University of Singapore ,  Centre National de la Recherche Scientifique

发明人： Virgile Nicolas Robert Viasnoff ,  Qiushi Li

IPC分类号： C12N5/00 ,  G01N33/50 ,  C12M1/12

CPC分类号： C12M25/04 ,  B01L3/5085 ,  C12M1/18 ,  C12M23/12 ,  C12M23/20 ,  C12M25/02 ,  C12N5/0062 ,  C12N5/0068 ,  C12N2529/10 ,  C12N2533/30 ,  C12N2533/52 ,  C12N2533/90 ,  C12N2537/10 ,  C12N2539/00 ,  G01N33/5014

摘要： The disclosure relates to the fabrication of a three dimensional [3-D] cell culture membrane comprising one or more functionalized surfaces adapted to provide cell culture conditions suitable for the analysis of proliferation, differentiation or function of cells, typically eukaryotic or prokaryotic cells.

摘要翻译： 本公开涉及三维[3-D]细胞培养膜的制造，所述三维[3-D]细胞培养膜包含一个或多个功能化表面，其适于提供适于分析细胞（通常为真核细胞或原核细胞）的增殖，分化或功能的细胞培养条件。

公开(公告)号：US12098415B2

公开(公告)日：2024-09-24

申请号：US18449087

申请日：2023-08-14

申请人： International Business Machines Corporation

发明人： Amos Cahan ,  Guy M. Cohen ,  Theodore G. van Kessel ,  Sufi Zafar

IPC分类号： G01N27/02 ,  C12M1/00 ,  C12M1/12 ,  C12M1/18 ,  C12M1/34 ,  C12M3/00 ,  C12Q1/02 ,  C12Q1/18 ,  G01N15/06 ,  G01N21/59 ,  G01N27/04

CPC分类号： C12Q1/02 ,  C12M1/18 ,  C12M1/3453 ,  C12M3/00 ,  C12M23/34 ,  C12M25/14 ,  C12M31/02 ,  C12M41/36 ,  C12Q1/18 ,  G01N15/0656 ,  G01N21/59 ,  G01N27/04 ,  C12N2533/76 ,  G01N27/02 ,  G01N2201/08

摘要： A structure for culturing cells includes growth medium regions on a surface of the structure. Each of the growth medium regions includes a growth medium surface configured to receive and promote growth in a cell that is being cultured. The structure includes a non-growth medium. The non-growth medium includes a non-growth medium surface configured to receive the cell that is being cultured.