公开(公告)号：US20070179596A1

公开(公告)日：2007-08-02

申请号：US11736137

申请日：2007-04-17

申请人： Luis Davila ,  David Lentz ,  Gerard Llanos ,  Jorge Mendez ,  Pallassana Narayanan ,  Alan Pelton ,  Mark Roller ,  Karl Scheidt ,  Angelo Scopelianos ,  William Shaw ,  James Silver ,  John Spaltro ,  Christine Trepanier ,  David Wilson

发明人： Luis Davila ,  David Lentz ,  Gerard Llanos ,  Jorge Mendez ,  Pallassana Narayanan ,  Alan Pelton ,  Mark Roller ,  Karl Scheidt ,  Angelo Scopelianos ,  William Shaw ,  James Silver ,  John Spaltro ,  Christine Trepanier ,  David Wilson

IPC分类号： A61F2/90

CPC分类号： A61B17/0644 ,  A61B17/00491 ,  A61B17/0469 ,  A61B17/11 ,  A61B17/115 ,  A61B2017/06028 ,  A61F2/064 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/3008 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2250/0067 ,  A61F2250/0098 ,  A61F2310/0097 ,  A61F2310/00976 ,  A61K31/436 ,  A61K31/727 ,  A61K45/06 ,  A61L17/145 ,  A61L27/34 ,  A61L29/085 ,  A61L31/022 ,  A61L31/10 ,  A61L31/16 ,  A61L31/18 ,  A61L2300/416 ,  A61L2300/608 ,  B05D1/18 ,  B05D3/0254 ,  B05D3/0493 ,  A61K2300/00 ,  C08L27/14 ,  C08L27/12 ,  C08L27/16

摘要： Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.

摘要翻译： 可以涂覆医疗装置，特别是可植入医疗装置，以最小化或基本上消除生物体对将生物体引入医疗装置的反应。 医疗装置可以涂覆任何数量的生物相容性材料。 治疗药物，药剂或化合物可以与生物相容性材料混合并固定在医疗装置的至少一部分上。 这些治疗药物，药剂或化合物还可以进一步减少生物体对将生物体引入医疗装置的反应。 可以使用各种材料和涂覆方法来将药物，试剂或化合物维持在医疗装置上，直到输送和定位。

公开(公告)号：US20070179595A1

公开(公告)日：2007-08-02

申请号：US11736043

申请日：2007-04-17

申请人： Luis Davila ,  David Lentz ,  Gerard Llanos ,  Jorge Mendez ,  Pallassana Narayanan ,  Alan Pelton ,  Mark Roller ,  Karl Scheidt ,  Angelo Scopelianos ,  William Shaw ,  James Silver ,  John Spaltro ,  Christine Trepanier ,  David Wilson

发明人： Luis Davila ,  David Lentz ,  Gerard Llanos ,  Jorge Mendez ,  Pallassana Narayanan ,  Alan Pelton ,  Mark Roller ,  Karl Scheidt ,  Angelo Scopelianos ,  William Shaw ,  James Silver ,  John Spaltro ,  Christine Trepanier ,  David Wilson

IPC分类号： A61F2/90 ,  A61L33/00 ,  B05D3/00

CPC分类号： A61B17/0644 ,  A61B17/00491 ,  A61B17/0469 ,  A61B17/11 ,  A61B17/115 ,  A61B2017/06028 ,  A61F2/064 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/3008 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2250/0067 ,  A61F2250/0098 ,  A61F2310/0097 ,  A61F2310/00976 ,  A61K31/436 ,  A61K31/727 ,  A61K45/06 ,  A61L17/145 ,  A61L27/34 ,  A61L29/085 ,  A61L31/022 ,  A61L31/10 ,  A61L31/16 ,  A61L31/18 ,  A61L2300/416 ,  A61L2300/608 ,  B05D1/18 ,  B05D3/0254 ,  B05D3/0493 ,  A61K2300/00 ,  C08L27/14 ,  C08L27/12 ,  C08L27/16

摘要： Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.

公开(公告)号：US20040197372A1

公开(公告)日：2004-10-07

申请号：US10827844

申请日：2004-04-20

发明人： Gerard H. Llanos ,  Pallassana Narayanan ,  Mark B. Roller ,  Angelo Scopelianos

IPC分类号： A61F002/00

CPC分类号： A61F2/91 ,  A61B17/00491 ,  A61B17/0469 ,  A61B17/0644 ,  A61B17/11 ,  A61B17/115 ,  A61B17/54 ,  A61B2017/06028 ,  A61F2/064 ,  A61F2250/0067 ,  A61F2310/0097 ,  A61F2310/00976 ,  A61L17/145 ,  A61L27/34 ,  A61L29/085 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/602 ,  A61L2300/606 ,  C08L27/14 ,  C08L27/12 ,  C08L27/16

摘要： The present invention includes biocompatible coatings and films for use on implantable medical devices and medical devices containing such coatings and films applied to a surface thereof, which coatings/films are present on the device in an amount effective to provide an inert surface to be in contact with body tissue of a mammal upon implantation of the device in the mammal, and contain a film-forming polyfluoro copolymer containing the polymerized residue of a moiety selected from the group consisting of vinylidenefluoride and tetrafluoroethylene copolymerized with a second moiety other than the first moiety, wherein the relative amounts of the polymerized residue of the first and second moieties are effective to provide the coating and films with properties effective for use in coating implantable med devices.

公开(公告)号：US20040102758A1

公开(公告)日：2004-05-27

申请号：US10636435

申请日：2003-08-07

发明人： Luis A. Davila ,  David Christian Lentz ,  Gerard H. Llanos ,  Jorge Orlando Mendez ,  Pallassana V. Narayanan ,  Alan Roy Pelton ,  Mark B. Roller ,  Karl K. Scheidt ,  Angelo George Scopelianos ,  William Douglas Shaw JR. ,  James H. Silver ,  John Spaltro ,  Christine Trepanier ,  David J. Wilson

IPC分类号： A61M031/00

CPC分类号： A61F2/91 ,  A61B17/00491 ,  A61B17/0469 ,  A61B17/0644 ,  A61B17/11 ,  A61B17/115 ,  A61B2017/06028 ,  A61F2/064 ,  A61F2/915 ,  A61F2002/3008 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2250/0067 ,  A61F2250/0098 ,  A61F2310/0097 ,  A61F2310/00976 ,  A61K31/436 ,  A61K31/727 ,  A61K45/06 ,  A61L17/145 ,  A61L27/34 ,  A61L29/085 ,  A61L31/022 ,  A61L31/10 ,  A61L31/16 ,  A61L31/18 ,  A61L2300/416 ,  A61L2300/608 ,  A61L2420/02 ,  B05D1/18 ,  B05D3/0254 ,  B05D3/0493 ,  A61K2300/00 ,  C08L27/20 ,  C08L27/16 ,  C08L27/14 ,  C08L27/12

摘要： Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.

摘要翻译： 可以涂覆医疗装置，特别是可植入医疗装置，以最小化或基本上消除生物体对将生物体引入医疗装置的反应。 医疗装置可以涂覆任何数量的生物相容性材料。 治疗药物，药剂或化合物可以与生物相容性材料混合并固定在医疗装置的至少一部分上。 这些治疗药物，药剂或化合物还可以进一步减少生物体对将生物体引入医疗装置的反应。 可以使用各种材料和涂覆方法来将药物，试剂或化合物维持在医疗装置上，直到输送和定位。

公开(公告)号：US20030065377A1

公开(公告)日：2003-04-03

申请号：US10136569

申请日：2002-04-30

发明人： Luis A. Davila ,  David J. Wilson

IPC分类号： A61F002/06 ,  A61M031/00

CPC分类号： A61F2/07 ,  A61B17/00491 ,  A61B17/0469 ,  A61B17/06166 ,  A61B17/0644 ,  A61B17/068 ,  A61B17/0684 ,  A61B17/0686 ,  A61B17/11 ,  A61B17/115 ,  A61B2017/00508 ,  A61B2017/00517 ,  A61B2017/06028 ,  A61B2017/0641 ,  A61B2017/081 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61F2/064 ,  A61F2/89 ,  A61F2/91 ,  A61F2/915 ,  A61F2/958 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/075 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2230/0013 ,  A61F2230/005 ,  A61F2250/0067 ,  A61F2310/0097 ,  A61F2310/00976 ,  A61L17/145 ,  A61L27/34 ,  A61L27/54 ,  A61L29/085 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/41 ,  A61L2300/416 ,  A61L2300/42 ,  A61L2300/45 ,  A61L2300/606 ,  A61M25/0045 ,  A61M2025/0057 ,  C08L27/12 ,  C08L27/16 ,  C08L27/14

摘要： Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.

公开(公告)号：US06303699B1

公开(公告)日：2001-10-16

申请号：US09252439

申请日：1999-02-18

申请人： Akihiro Naraki ,  Takashi Sato

发明人： Akihiro Naraki ,  Takashi Sato

IPC分类号： C08F818

CPC分类号： C08K5/14 ,  C08K3/22 ,  C08K5/34924 ,  C08L27/14 ,  C08L27/12

摘要： Disclosed is a vulcanizable fluororubber composition comprising (a) a tetrafluoroethylene/perfluoroalkyl vinyl ether copolymer, (b) an organic peroxide, (c) a co-crosslinking agent and (d) hydrotalcite. The copolymer (a) preferably contains an iodine atom or a bromine atom. The vulcanizable fluororubber composition preferably further comprises carbon black or titanium oxide. When the vulcanizable fluororubber composition is vulcanized, the resulting vulcanizate has excellent compression set and is relatively non-toxic.

摘要翻译： 公开了一种可硫化的氟橡胶组合物，其包含（a）四氟乙烯/全氟烷基乙烯基醚共聚物，（b）有机过氧化物，（c）共交联剂和（d）水滑石。 共聚物（a）优选含有碘原子或溴原子。 可硫化氟橡胶组合物优选还包含炭黑或氧化钛。 当可硫化氟橡胶组合物硫化时，得到的硫化橡胶具有优异的压缩永久变形，并且是相对无毒的。

公开(公告)号：US5270115A

公开(公告)日：1993-12-14

申请号：US042479

申请日：1993-04-02

申请人： Liberato Mascia ,  Giovanni Moggi

发明人： Liberato Mascia ,  Giovanni Moggi

IPC分类号： C04B41/48 ,  C08L27/14 ,  C08L27/16 ,  C08L33/06 ,  C09D127/16 ,  D06M15/256 ,  D06M15/263 ,  C08L27/08 ,  B32B15/08 ,  B32B27/04

CPC分类号： D06M15/263 ,  C04B41/4842 ,  C08L27/16 ,  C09D127/16 ,  D06M15/256 ,  C08L2205/02 ,  C08L27/14 ,  C08L33/06 ,  Y10T428/31544 ,  Y10T442/2189

摘要： Reversible polymer gels comprising:(a) 55-98% by weight based on the total polymers contained in the gel, of an elastomeric copolymer of vinylidene fluoride comprising, in moles, 55-85% of vinylidene fluoride, 15-45% of hexafluoropropene and 0.30% of tetrafluoroethylene;(b) 2-45% based on the total polymers contained in the gel, of a non-elastomeric polymer selected from non-elastomeric VDF. based polymers, or polyvinylfluoride, or acrylic resins, for example polyalkylmethacrylates and copolymers of alkylmethacrylates with alkylacrylates, having T.sub.g >50.degree. C.Said polymer gels can be used as protective and consolidating agents for stone materials, for preparing insulating and impermeable films and for impregnating fiber textiles

摘要翻译： 可逆聚合物凝胶包含：（a）基于凝胶中包含的总聚合物的55-98重量％的偏二氟乙烯的弹性共聚物，其摩尔数为55-85％的偏二氟乙烯，15-45％的六氟丙烯 和0.30％的四氟乙烯; （b）基于凝胶中包含的总聚合物，选自非弹性体VDF的非弹性体聚合物的2-45％。 基于聚合物或聚氟乙烯或丙烯酸树脂，例如聚甲基丙烯酸烷基酯和甲基丙烯酸烷基酯与丙烯酸烷基酯的共聚物，Tg> 50℃。所述聚合物凝胶可用作石材的保护和固结剂，用于制备绝缘和不渗透膜， 浸渍纤维纺织品

公开(公告)号：US5219661A

公开(公告)日：1993-06-15

申请号：US767121

申请日：1991-09-27

申请人： Liberato Mascia ,  Giovanni Moggi

发明人： Liberato Mascia ,  Giovanni Moggi

IPC分类号： C08L27/14 ,  C04B41/48 ,  C08L27/00 ,  C08L27/16 ,  C08L27/20 ,  C08L33/00 ,  C08L33/04 ,  C08L33/06 ,  C08L33/08 ,  C09D127/12 ,  C09D127/16 ,  D06M15/256 ,  D06M15/263

CPC分类号： D06M15/263 ,  C04B41/4842 ,  C08L27/16 ,  C09D127/16 ,  D06M15/256 ,  C08L2205/02 ,  C08L27/14 ,  C08L33/06 ,  Y10T428/3154 ,  Y10T428/31544 ,  Y10T428/4935

摘要： Reversible polymer gels comprising:(a) 55-98% by weight based on the total polymers contained in the gel, of an elastomeric copolymer of vinylidene fluoride comprising, in moles, 55-85% of vinylidene fluoride, 15-45% of hexafluoropropene and 0-30% of tetrafluoroethylene;(b) 2-45% based on the total polymers contained in the gel, of a non-elastomeric polymer selected from non-elastomeric VDF-based polymers, or polyvinylfluoride, or acrylic resins, for example polyalkylmethacrylates and copolymers of alkylmethacrylates with alkylacrylates, having T.sub.g >50.degree. C.Said polymer gels can be used as protective and consolidating agents for stone materials, for preparing insulating and impermeable films and for impregnating fiber textiles.

公开(公告)号：US3557050A

公开(公告)日：1971-01-19

申请号：US3557050D

申请日：1968-03-05

申请人： DAIKIN IND LTD ,  KANSAI PAINT CO LTD

发明人： KOIZUMI SHUN ,  INAMURA KEIZO

IPC分类号： C08K5/00 ,  C08F45/58 ,  C08F45/60 ,  C08F45/62

CPC分类号： C08K5/005 ,  C08L27/14

摘要： A HEAT-STABLE COMPOSITION COMPRISING A VINYL FLUORIDE POLYMER, 0.01 TO 5 WEIGHT PERCENT OF AN ALKALI METAL FORMATE, BASED ON THE WEIGHT OF THE VINYL FLUORIDE POLYMER AND 0.01 TO 5 WEIGHT PERCENT OF AN ORGANIC ANTIOXIDANT HAVING A BOILING POINT OF HIGHER THAN THE MELTING POINT OF THE VINYL FLUORIDE POLYMER, BASED ON THE WEIGHT OF THE VINYL FLUORIDE POLYMER.

公开(公告)号：US3234172A

公开(公告)日：1966-02-08

申请号：US15916161

申请日：1961-12-13

申请人： DU PONT

发明人： NICOLL WILLIAM D

IPC分类号： C08K5/053

CPC分类号： C08K5/053 ,  C08L27/14