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公开(公告)号：US09844384B2
公开(公告)日：2017-12-19
申请号：US13179960
申请日：2011-07-11
Applicant: Boris Chernov , Nataliya Chernova , Igoris Misuchenko , Georgy Martsinovskiy , Mikhail Verbitsky
Inventor： Boris Chernov , Igoris Misuchenko , Georgy Martsinovskiy , Mikhail Verbitsky
IPC: A61B18/18 , A61B17/122 , A61B18/14 , A61B5/05 , A61B18/20 , A61B17/00 , A61B18/00 , A61B18/12 , A61B90/00
CPC classification number: A61B17/122 , A61B5/05 , A61B18/1442 , A61B18/20 , A61B2017/00004 , A61B2017/00026 , A61B2017/00119 , A61B2017/00199 , A61B2017/00221 , A61B2017/00517 , A61B2017/00734 , A61B2017/00867 , A61B2018/00273 , A61B2018/00428 , A61B2018/00607 , A61B2018/0063 , A61B2018/00642 , A61B2018/00702 , A61B2018/00779 , A61B2018/00875 , A61B2018/1226 , A61B2090/065
Abstract: The present disclosure is directed to a tissue clip for use in electrosurgical procedures. The tissue clip includes an arm having a first electrode formed thereon. The tissue clip also includes a body pivotally coupled to the arm. The body includes a power source and a second electrode. The arm is moveable from a first position relative to the body for approximating tissue and a second position closer to the body for grasping tissue therebetween.
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公开(公告)号：US20050038471A1
公开(公告)日：2005-02-17
申请号：US10732032
申请日：2003-12-09
Applicant: Barbara Chan , Timothy Johnson , Irene Kochevar , Mark Randolph , Robert Redmond , Jonathan Winograd
Inventor： Barbara Chan , Timothy Johnson , Irene Kochevar , Mark Randolph , Robert Redmond , Jonathan Winograd
CPC classification number: A61B17/11 , A61B2017/00508 , A61B2017/00517 , A61F9/0079 , A61F9/0081 , A61F9/00821 , A61F2009/00842 , A61F2009/00853 , A61F2009/00872 , A61F2009/00887 , A61L24/001 , A61L2430/32 , A61N5/062
Abstract: Photochemical tissue boding methods for bonding neural tissues include the application of a photosensitizer to a tissue and/or tissue graft, followed by irradiation with electromagnetic energy to produce a tissue seal. The methods are useful for tissue adhesion, such as in wound closure, tissue grafting, skin grafting, musculoskeletal tissue repair, ligament or tendon repair, neural repair, blood vessel repair and corneal repair.
Abstract translation: 用于粘合神经组织的光化学组织编织方法包括将光敏剂施用于组织和/或组织移植物，随后用电磁能照射以产生组织密封。 该方法可用于组织粘连，例如伤口闭合，组织移植，皮肤移植，肌肉骨骼组织修复，韧带或肌腱修复，神经修复，血管修复和角膜修复。
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公开(公告)号：US20030216718A1
公开(公告)日：2003-11-20
申请号：US10462179
申请日：2003-06-16
Inventor： Michael R. Hamblin , John J. Khadem
IPC: A61B018/20
CPC classification number: A61L31/043 , A61B2017/00517 , A61L31/14
Abstract: Various tissue glues have drawback such as toxicity, causing inflammatory reactions or insufficient bonding strength. The present invention is directed to methods of form tissue adhesion by administering to tissues compositions comprising proteins conjugated to one or more novel photosensitizers and irradiating the composition. The composition may further comprise one or more proteins not conjugated to the photosensitizer. Additionally, the present invention relates to compositions and methods wherein increased ratios of protein to photosensitizer enhance weld strength.
Abstract translation: 各种组织胶具有毒性，引起炎症反应或粘合强度不足等缺点。 本发明涉及通过给予包含与一种或多种新型光敏剂缀合的蛋白质并照射该组合物的组合物组合来形成组织粘附的方法。 该组合物可进一步包含一种或多种未偶联于光敏剂的蛋白质。 另外，本发明涉及组合物和方法，其中蛋白质与光敏剂的比例增加增强了焊接强度。
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公开(公告)号：US06607522B1
公开(公告)日：2003-08-19
申请号：US09527369
申请日：2000-03-16
Applicant: Michael R. Hamblin , John Khadem
Inventor： Michael R. Hamblin , John Khadem
IPC: A61B1818
CPC classification number: A61L31/043 , A61B2017/00517 , A61L31/14
Abstract: Various tissue glues have drawback such as toxicity, causing inflammatory reactions or insufficient bonding strength. The invention is directed to methods of form tissue adhesion by administering to tissues compositions comprising proteins conjugated to one or more novel photosensitizers and irradiating the composition. The composition may further comprise one or more proteins not conjugated to the photosensitizer. Additionally, the present invention relates to compositions and methods wherein increased ratios of protein to photosensitizer enhance weld strength.
Abstract translation: 各种组织胶具有毒性，引起炎症反应或粘合强度不足等缺点。 本发明涉及通过给予包含与一种或多种新型光敏剂缀合的蛋白质的组合组合物并照射该组合物来形成组织粘附的方法。 该组合物可进一步包含一种或多种未偶联于光敏剂的蛋白质。 另外，本发明涉及组合物和方法，其中蛋白质与光敏剂的比例增加增强了焊接强度。
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公开(公告)号：US20030065377A1
公开(公告)日：2003-04-03
申请号：US10136569
申请日：2002-04-30
Inventor： Luis A. Davila , David J. Wilson
IPC: A61F002/06 , A61M031/00
CPC classification number: A61F2/07 , A61B17/00491 , A61B17/0469 , A61B17/06166 , A61B17/0644 , A61B17/068 , A61B17/0684 , A61B17/0686 , A61B17/11 , A61B17/115 , A61B2017/00508 , A61B2017/00517 , A61B2017/06028 , A61B2017/0641 , A61B2017/081 , A61B2017/1107 , A61B2017/1135 , A61F2/064 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/91533 , A61F2002/91558 , A61F2230/0013 , A61F2230/005 , A61F2250/0067 , A61F2310/0097 , A61F2310/00976 , A61L17/145 , A61L27/34 , A61L27/54 , A61L29/085 , A61L31/10 , A61L31/16 , A61L2300/41 , A61L2300/416 , A61L2300/42 , A61L2300/45 , A61L2300/606 , A61M25/0045 , A61M2025/0057 , C08L27/12 , C08L27/16 , C08L27/14
Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.
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Patent Agency Ranking
公开(公告)号：US20030065345A1
公开(公告)日：2003-04-03
申请号：US10274770
申请日：2002-10-21
Inventor： Kevin Weadock
IPC: A61B017/08
CPC classification number: A61F2/07 , A61B17/00491 , A61B17/0469 , A61B17/06166 , A61B17/0644 , A61B17/068 , A61B17/0684 , A61B17/0686 , A61B17/11 , A61B17/115 , A61B2017/00508 , A61B2017/00517 , A61B2017/00893 , A61B2017/06028 , A61B2017/0641 , A61B2017/081 , A61B2017/1107 , A61B2017/1135 , A61F2/064 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2230/0013 , A61F2230/005 , A61F2250/0067 , A61F2310/0097 , A61L27/34 , A61L27/54 , A61L31/10 , A61L2300/41 , A61L2300/416 , A61L2300/42 , A61M25/0045 , A61M2025/0057 , C08L27/12
Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.
Abstract translation: 可以涂覆医疗装置，特别是可植入医疗装置，以最小化或基本上消除生物体对将生物体引入医疗装置的反应。 医疗装置可以涂覆任何数量的生物相容性材料。 治疗药物，药剂或化合物可以与生物相容性材料混合并固定在医疗装置的至少一部分上。 这些治疗药物，药剂或化合物还可以进一步减少生物体对将生物体引入医疗装置的反应。 可以使用各种材料和涂覆方法来将药物，试剂或化合物维持在医疗装置上，直到输送和定位。
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公开(公告)号：US20170281191A1
公开(公告)日：2017-10-05
申请号：US15628051
申请日：2017-06-20
Applicant: COVIDIEN LP
Inventor： Boris Chernov , Igoris Misuchenko , Georgy Martsinovskiy , Mikhail Verbitsky
IPC: A61B17/122
CPC classification number: A61B17/122 , A61B5/05 , A61B18/1442 , A61B18/20 , A61B2017/00004 , A61B2017/00026 , A61B2017/00119 , A61B2017/00199 , A61B2017/00221 , A61B2017/00517 , A61B2017/00734 , A61B2017/00867 , A61B2018/00273 , A61B2018/00428 , A61B2018/00607 , A61B2018/0063 , A61B2018/00642 , A61B2018/00702 , A61B2018/00779 , A61B2018/00875 , A61B2018/1226 , A61B2090/065
Abstract: A tissue clip for use in electrosurgical procedures includes an arm having a first electrode formed thereon. The tissue clip also includes a body pivotally coupled to the arm. The body includes a power source and a second electrode. The arm is moveable from a first position relative to the body for approximating tissue and a second position closer to the body for grasping tissue therebetween.
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公开(公告)号：US20150351767A1
公开(公告)日：2015-12-10
申请号：US14614644
申请日：2015-02-05
Applicant: Boston Scientific Scimed, Inc.
Inventor： Jonathan ZOLL , Peter J. Pereira , Michael S.H. Chu
CPC classification number: A61B17/11 , A61B17/00491 , A61B17/1114 , A61B17/1204 , A61B17/12136 , A61B18/24 , A61B2017/00084 , A61B2017/00199 , A61B2017/00508 , A61B2017/00517 , A61B2017/00831 , A61B2017/00893 , A61B2017/00907 , A61B2017/1132 , A61B2018/00517 , A61B2018/00619 , A61B2018/0063 , A61M25/0023 , A61M25/1002 , A61M2025/1081
Abstract: The present disclosure is directed to methods, compositions, devices and kits which pertain to the attachment of one body conduit portion to another body conduit portion by application of an energy source to body conduit portions in the presence of a bonding material.
Abstract translation: 本公开涉及涉及通过在存在接合材料的情况下将能量源施加到身体导管部分而将一个体导管部分附接到另一个体导管部分的方法，组合物，装置和试剂盒。
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9.发明申请TAILOR-MADE STENT GRAFT AND PROCEDURE FOR MINIMALLY INVASIVE ANEURYSM REPAIR WITH NOVEL TAILOR-MADE BALLOON, NOVEL GUIDEWIRE, AND NOVEL CAPSULATED BIOGLUE 审中-公开用户可以使用新的制造商制造的气球，新颖的GUIDEWIRE和新型的封闭式生物技术来进行最小的入侵手术修复和手术公开(公告)号：US20140018902A1
公开(公告)日：2014-01-16
申请号：US13547467
申请日：2012-07-12
Applicant: David MYR
Inventor： David MYR
IPC: A61F2/06
CPC classification number: A61F2/07 , A61B17/00491 , A61B17/12118 , A61B2017/00508 , A61B2017/00517 , A61B2017/00526 , A61F2/958 , A61F2002/072 , A61L31/044 , A61L31/14 , A61L31/16 , A61L2300/418 , A61L2300/624 , A61L2420/08
Abstract: An individually tailored endovascular stent graft device and procedure is for performing a no-cut repair of different aneurysm types: ascending, descending, arch, abdominal and cerebral aneurysms. Many aneurysm types can thus be treated without the need for open heart surgery. The stent may be biomaterial based (collagen-based in the preferred embodiment). No shape-memory metals need be used therefore allowing better implantation flexibility and better patient recovery. The stent may be fixated in the designated treatment area by remotely activating individually capsulated bicomponent biological glue by UV light/ultrasound means, wherein each component of the glue is coated separately. Further presented is a method for calculating stent graft implantation path by determining the sequence of implantation points through computer simulation means, wherein the implantation is done by discrete pulses.
Abstract translation: 单独定制的血管内支架移植装置和程序用于执行不同动脉瘤类型的无切割修复：上升，下降，拱形，腹部和脑动脉瘤。 因此，可以治疗许多动脉瘤类型，而不需要开心手术。 支架可以是基于生物材料的（在优选实施例中基于胶原）。 不需要使用形状记忆金属，因此允许更好的植入灵活性和更好的患者恢复。 通过用UV光/超声波装置远程激活单独封装的双组分生物胶，将支架固定在指定的治疗区域，其中胶水的每个组分被单独涂覆。 进一步提出的是通过计算机模拟装置确定植入点的顺序来计算支架移植物植入路径的方法，其中通过离散脉冲进行注入。
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公开(公告)号：US20130018364A1
公开(公告)日：2013-01-17
申请号：US13179960
申请日：2011-07-11
Applicant: Igoris Misuchenko , Georgy Martsinovskiy , Mikhail Verbitsky , Nataliya Chernova
Inventor： Boris Chernov , Igoris Misuchenko , Georgy Martsinovskiy , Mikhail Verbitsky
CPC classification number: A61B17/122 , A61B5/05 , A61B18/1442 , A61B18/20 , A61B2017/00004 , A61B2017/00026 , A61B2017/00119 , A61B2017/00199 , A61B2017/00221 , A61B2017/00517 , A61B2017/00734 , A61B2017/00867 , A61B2018/00273 , A61B2018/00428 , A61B2018/00607 , A61B2018/0063 , A61B2018/00642 , A61B2018/00702 , A61B2018/00779 , A61B2018/00875 , A61B2018/1226 , A61B2090/065
Abstract: The present disclosure is directed to a tissue clip for use in electrosurgical procedures. The tissue clip includes an arm having a first electrode formed thereon. The tissue clip also includes a body pivotally coupled to the arm. The body includes a power source and a second electrode. The arm is moveable from a first position relative to the body for approximating tissue and a second position closer to the body for grasping tissue therebetween
Abstract translation: 本公开涉及用于电外科手术的组织夹。 组织夹具包括其上形成有第一电极的臂。 组织夹还包括枢转地联接到臂的主体。 主体包括电源和第二电极。 臂可以相对于身体的第一位置移动以近似组织，并且靠近身体的第二位置用于抓住组织
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