公开(公告)号：US20190024109A1

公开(公告)日：2019-01-24

申请号：US16043477

申请日：2018-07-24

申请人： Spogen Biotech Inc. ,  Nufarm Limited

发明人： Brian Thompson

IPC分类号： C12N15/82 ,  C12N9/04 ,  C12N15/74 ,  A01N25/12 ,  C08G64/30 ,  C12N9/02

CPC分类号： C12N15/8274 ,  A01N25/12 ,  A01N25/32 ,  C08G64/30 ,  C12N9/0006 ,  C12N9/0071 ,  C12N15/74 ,  C12Y101/01 ,  C12Y114/11 ,  C12Y114/13001 ,  C12Y114/13002 ,  C12Y114/13063 ,  C12Y308/01008

摘要： Herbicide-detoxifying enzymes, compositions containing one or more of the enzymes, and plant seeds treated with the enzymes are provided. The enzymes can be used in methods for detoxifying auxin herbicides or degrading auxin plant regulators, including in methods for decontaminating surface of an apparatus used in agriculture or pesticide manufacturing, methods for decontaminating water, soil, soilless media, or sludge, and methods for protecting a plant from an auxin herbicide, improving a plant's tolerance to an auxin herbicide, or removing an auxin herbicide from the surface of a plant.

公开(公告)号：US20170145158A1

公开(公告)日：2017-05-25

申请号：US15321859

申请日：2015-07-02

申请人： Mitsubishi Gas Chemical Company, Inc.

发明人： Takeo HAYASHI ,  Hideyuki SATO

IPC分类号： C08G64/02 ,  C08G18/10 ,  C08G64/42 ,  C08G18/44 ,  C08G64/30 ,  C08G64/18

CPC分类号： C08G64/0208 ,  C08G18/10 ,  C08G18/44 ,  C08G18/7671 ,  C08G64/02 ,  C08G64/18 ,  C08G64/30 ,  C08G64/42 ,  C08G18/3206

摘要： Provided is a polycarbonates that can be used as starting materials for polyurethanes having excellent weather resistance and heat aging resistance. Provided is polyurethanes and elastomers obtained by using the polycarbonates, as well as processes for manufacturing the polycarbonates and processes for manufacturing the polyurethanes. The polycarbonate contains one or more types of repeating unit represented by formula [I] below, which contains 90% or more of terminal hydroxyl groups; wherein R1, R2, R3 and R4 each independently represent an aliphatic hydrocarbon group containing 1 to 6 carbon atoms.

公开(公告)号：US20170114182A1

公开(公告)日：2017-04-27

申请号：US15397193

申请日：2017-01-03

申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION ,  AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

发明人： Kazuki Fukushima ,  James L. Hedrick ,  Yi Yan Yang

IPC分类号： C08G63/64 ,  C08G64/30 ,  A61K47/34 ,  C08G64/42 ,  C08G63/91 ,  C08G64/18 ,  C12N15/88 ,  C08G64/02

CPC分类号： C08G63/64 ,  A61K47/34 ,  C08G63/06 ,  C08G63/912 ,  C08G64/0208 ,  C08G64/0241 ,  C08G64/18 ,  C08G64/30 ,  C08G64/38 ,  C08G64/42 ,  C08G2261/126 ,  C12N5/0068 ,  C12N15/88 ,  C12N2533/30 ,  Y02P20/582

摘要： A biodegradable cationic polymer is disclosed, comprising first repeat units derived from a first cyclic carbonyl monomer by ring-opening polymerization, wherein more than 0% of the first repeat units comprise a side chain moiety comprising a quaternary amine group; a subunit derived from a monomeric diol initiator for the ring-opening polymerization; and an optional endcap group. The biodegradable cationic polymers have low cytotoxicity and form complexes with biologically active materials useful in gene therapeutics and drug delivery.

公开(公告)号：US09562127B2

公开(公告)日：2017-02-07

申请号：US14280167

申请日：2014-05-16

申请人： International Business Machines Corporation

发明人： Joy Cheng ,  Anindarupa Chunder ,  Daniel P. Sanders ,  Melia Tjio ,  Ankit Vora

IPC分类号： C08F283/00 ,  C09D169/00 ,  C08F293/00

CPC分类号： C08G64/18 ,  B82Y40/00 ,  C08F293/00 ,  C08F2438/01 ,  C08G64/30 ,  C08G81/027 ,  C09D169/00 ,  G03F7/0002

摘要： Block polymers are formed by ring opening polymerization (ROP) of a cyclic carbonate monomer using a polymeric initiator for the ROP that comprises repeating functionalized ethylene units. The block polymers are free of, or substantially free of, any polymer having a chemical structure that does not comprise the polymer backbone of the polymeric initiator. The block polymers are capable of directed self-assembly.

摘要翻译： 嵌段聚合物通过使用包含重复官能化乙烯单元的用于ROP的聚合引发剂的环状碳酸酯单体的开环聚合（ROP）形成。 嵌段聚合物不含或基本上不含具有不包含聚合物引发剂的聚合物主链的化学结构的任何聚合物。 嵌段聚合物能够引导自组装。

公开(公告)号：US09493606B2

公开(公告)日：2016-11-15

申请号：US13825513

申请日：2011-09-02

申请人： Marion Helou ,  Sophie Guillaume ,  Jean-François Carpentier ,  Martine Slawinski ,  William Guerin

发明人： Marion Helou ,  Sophie Guillaume ,  Jean-François Carpentier ,  Martine Slawinski ,  William Guerin

IPC分类号： C08G63/08 ,  C08G63/64 ,  C08G63/87 ,  C08G64/02 ,  C08G64/18 ,  C08G64/30 ,  C08G63/83 ,  C08G63/84

CPC分类号： C08G63/87 ,  C08G63/08 ,  C08G63/64 ,  C08G63/83 ,  C08G63/84 ,  C08G64/0208 ,  C08G64/18 ,  C08G64/30

摘要： The present invention relates to the field of tailored di-, tri- and multi-block as well as gradient polyesters/polycarbonates copolymers prepared by introducing monomers simultaneously in the reaction medium in the presence of an organometallic, metal salt or organic catalyst.

摘要翻译： 本发明涉及通过在有机金属，金属盐或有机催化剂的存在下在反应介质中同时引入单体而制备的定制的二，三和多嵌段以及梯度聚酯/聚碳酸酯共聚物的领域。

公开(公告)号：US20160257782A1

公开(公告)日：2016-09-08

申请号：US15154948

申请日：2016-05-14

申请人： International Business Machines Corporation ,  Agency For Science, Technology and Research

发明人： Daniel J. Coady ,  Richard A. Dipietro ,  Amanda C. Engler ,  James L. Hedrick ,  Victor M. L. Ng ,  Zhan-Yuin Ong ,  Jeremy P.K. Tan ,  Yi Yan Yang

IPC分类号： C08G63/64 ,  A61K9/00 ,  A61K31/765

CPC分类号： C08G63/64 ,  A01N33/12 ,  A01N43/50 ,  A01N57/34 ,  A61K9/0019 ,  A61K31/765 ,  A61K2800/54 ,  A61K2800/542 ,  A61K2800/5426 ,  C08G64/0233 ,  C08G64/0241 ,  C08G64/025 ,  C08G64/0258 ,  C08G64/0291 ,  C08G64/30 ,  A01N45/00

摘要： Antimicrobial cationic polymers having one or two cationic polycarbonate chains were prepared by organocatalyzed ring opening polymerization. One antimicrobial cationic polymer has a polymer chain consisting essentially of cationic carbonate repeat units linked to one or two end groups. The end groups can comprise a covalently bound form of biologically active compound such as cholesterol. Other antimicrobial cationic polymers have a random copolycarbonate chain comprising a minor mole fraction of hydrophobic repeat units bearing a covalently bound form of a vitamin E and/or vitamin D2. The cationic polymers exhibit high activity and selectivity against Gram-negative and Gram-positive microbes and fungi.

摘要翻译： 通过有机催化开环聚合制备具有一个或两个阳离子聚碳酸酯链的抗微生物阳离子聚合物。 一种抗微生物阳离子聚合物具有基本上由连接到一个或两个端基的阳离子碳酸酯重复单元组成的聚合物链。 末端基团可包含共价结合形式的生物活性化合物如胆固醇。 其它抗微生物阳离子聚合物具有无规共聚碳酸酯链，其包含具有共价结合形式的维生素E和/或维生素D2的疏水重复单元的较小摩尔分数。 阳离子聚合物对革兰氏阴性和革兰氏阳性微生物和真菌表现出高活性和选择性。

公开(公告)号：US09243106B2

公开(公告)日：2016-01-26

申请号：US14400640

申请日：2013-05-14

申请人： MITSUBISHI GAS CHEMICAL COMPANY, INC.

发明人： Yoshinori Isahaya ,  Atsushi Hirashima ,  Hidefumi Harada ,  Maki Ito ,  Jun-ya Hayakawa ,  Takehiko Isobe ,  Taichi Tokutake ,  Yousuke Shinkai

IPC分类号： C08G64/00 ,  C08G64/30 ,  C08G64/16 ,  C08G64/06 ,  C08G63/02

CPC分类号： C08G64/307 ,  C08G64/06 ,  C08G64/1608 ,  C08G64/205 ,  C08G64/30 ,  C08G64/305

摘要： A high molecular weight polycarbonate resin is continuously produced by subjecting an aromatic polycarbonate prepolymer and an aliphatic diol compound to a linking and highly polymerizing reaction. Even an aliphatic diol compound having a comparatively low boiling point can be allowed to efficiently contribute to the linking and highly polymerizing reaction. An aromatic polycarbonate prepolymer is produced by a polycondensation reaction between an aromatic dihydroxy compound and a diester carbonate, adding an aliphatic diol compound having an aliphatic group bonding to a terminal hydroxyl group to obtain a prepolymer mixture, and subjecting the resulting prepolymer mixture to a linking and highly polymerizing reaction under reduced pressure. The aliphatic diol compound is added at a pressure exceeding 200 torr, and the prepolymer mixture is subjected to a linking and highly polymerizing reaction before the terminal hydroxyl group concentration of the aromatic polycarbonate prepolymer in the prepolymer mixture reaches 2000 ppm.

摘要翻译： 通过使芳族聚碳酸酯预聚物和脂族二醇化合物进行连接和高度聚合反应来连续制备高分子量聚碳酸酯树脂。 甚至可以使具有较低沸点的脂族二醇化合物有效地促进连接和高度聚合反应。 通过芳香族二羟基化合物与碳酸二酯之间的缩聚反应生成芳香族聚碳酸酯预聚物，加入具有与末端羟基键合的脂肪族二醇化合物，得到预聚物混合物，将所得预聚物混合物进行连接 并在减压下进行高度聚合反应。 在超过200托的压力下加入脂族二醇化合物，预聚物混合物在预聚物混合物中的芳族聚碳酸酯预聚物的末端羟基浓度达到2000ppm之前进行连接和高度聚合反应。

公开(公告)号：US20160009860A1

公开(公告)日：2016-01-14

申请号：US14862365

申请日：2015-09-23

申请人： International Business Machines Corporation ,  Agency For Science, Technology and Research

发明人： Mareva B. Fevre ,  James L. Hedrick ,  Victor W.L. Ng ,  Robert J. Ono ,  Shrinivas Venkataraman ,  Zhi Xiang Voo ,  Yi Yan Yang

IPC分类号： C08G64/16 ,  C07D273/01 ,  C07D323/00 ,  C08G64/02

CPC分类号： C07D323/00 ,  A01N47/06 ,  C07D273/01 ,  C08G64/0241 ,  C08G64/30

摘要： Eight-membered ring cyclic carbonates having an oxygen or an acylated nitrogen at position 6 were prepared by reaction of precursor diols with ethyl chloroformate. The cyclic carbonates undergo organocatalyzed ring opening polymerization. In one instance, the initial polymer formed comprises a carbonate repeat unit having a Boc-protected nitrogen in the polymer backbone. Deprotecting the nitrogen with acid forms a cationic carbonate repeat unit having a positive charged secondary ammonium nitrogen in the polymer backbone.

摘要翻译： 通过前体二醇与氯甲酸乙酯的反应制备在6位具有氧或酰化氮的八元环状碳酸酯。 环状碳酸酯进行有机催化开环聚合。 在一种情况下，形成的初始聚合物包含在聚合物主链中具有Boc-保护的氮的碳酸酯重复单元。 用酸去保护氮气形成在聚合物主链中具有带正电荷的仲铵氮的阳离子碳酸酯重复单元。

公开(公告)号：US09115111B2

公开(公告)日：2015-08-25

申请号：US13510625

申请日：2010-11-19

申请人： Henri Cramail ,  Aurelie Boyer ,  Eric Cloutet ,  Benoit Gadenne ,  Alfos Carine

发明人： Henri Cramail ,  Aurelie Boyer ,  Eric Cloutet ,  Benoit Gadenne ,  Alfos Carine

IPC分类号： C08F2/48 ,  C07D317/36 ,  C08G64/30 ,  C07D317/38 ,  C08G71/04

CPC分类号： C07D317/36 ,  C07D317/38 ,  C08G64/30 ,  C08G71/04

摘要： The present invention concerns a compound of following formula (I): where: R1 is H or an alkyl group, A1 is a divalent straight-chain or branched alkylene radical, and A2 is a —O-A4-O— radical, A4 is a divalent straight-chain or branched alkylene radical.

摘要翻译： 本发明涉及下式（I）的化合物：其中：R1为H或烷基，A1为二价直链或支链亚烷基，A2为-O-A4-O-基，A4为 二价直链或支链亚烷基。

公开(公告)号：US20140301968A1

公开(公告)日：2014-10-09

申请号：US13859048

申请日：2013-04-09

申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION ,  AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

发明人： Daniel J. Coady ,  Richard A. Dipietro ,  Amanda C. Engler ,  James L. Hedrick ,  Victor W. L. Ng ,  Zhan-Yuin Ong ,  Jeremy P. K. Tan ,  Yi Yan Yang

IPC分类号： A01N47/06

CPC分类号： C08G63/64 ,  A01N33/12 ,  A01N43/50 ,  A01N57/34 ,  A61K9/0019 ,  A61K31/765 ,  A61K2800/54 ,  A61K2800/542 ,  A61K2800/5426 ,  C08G64/0233 ,  C08G64/0241 ,  C08G64/025 ,  C08G64/0258 ,  C08G64/0291 ,  C08G64/30 ,  A01N45/00

摘要： Antimicrobial cationic polymers having one or two cationic polycarbonate chains were prepared by organocatalyzed ring opening polymerization. One antimicrobial cationic polymer has a polymer chain consisting essentially of cationic carbonate repeat units linked to one or two end groups. The end groups can comprise a covalently bound form of biologically active compound such as cholesterol. Other antimicrobial cationic polymers have a random copolycarbonate chain comprising a minor mole fraction of hydrophobic repeat units bearing a covalently bound form of a vitamin E and/or vitamin D2. The cationic polymers exhibit high activity and selectivity against Gram-negative and Gram-positive microbes and fungi.