知搜-全球专利检索

  1. 登录
  2. 注册

搜索结果

221 条记录 (耗时 0.032 秒)

    LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
    6.
    发明申请
    LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE 有权
    液晶组合物和液晶显示装置

    公开(公告)号：US20160090531A1

    公开(公告)日：2016-03-31

    申请号：US14825162

    申请日：2015-08-12

    申请人： JNC CORPORATION ,  JNC PETROCHEMICAL CORPORATION

    发明人： ERIKO KURIHARA ,  MASAYUKI SAITO ,  YOSHIMASA FURUSATO

    IPC分类号： C09K19/34 ,  C09K19/54 ,  C07C43/225 ,  C07C57/62 ,  C07C13/28 ,  C07C15/14 ,  C07D311/60 ,  C09K19/30 ,  C07D309/06

    CPC分类号： C09K19/3402 ,  C07C43/225 ,  C07C57/62 ,  C07D309/06 ,  C07D311/60 ,  C09K19/3048 ,  C09K19/3066 ,  C09K19/3068 ,  C09K19/3098 ,  C09K2019/0448 ,  C09K2019/123 ,  C09K2019/3004 ,  C09K2019/3016 ,  C09K2019/3021 ,  C09K2019/3078 ,  C09K2019/3422 ,  C09K2019/3425 ,  C09K2019/548

    摘要： A liquid crystal composition having at least one or a suitable balance regarding at least two of characteristics such as high maximum temperature of a nematic phase, low minimum temperature thereof, small viscosity, suitable optical anisotropy, large negative dielectric anisotropy, large specific resistance, high stability to ultraviolet light or heat and a large elastic constant; an AM device having characteristics such as short response time, a large voltage holding ratio, low threshold voltage, a large contrast ratio and long service life are described. The liquid crystal composition has negative dielectric anisotropy, and contains a specific compound having negatively large dielectric anisotropy and a large elastic constant as a first component, and may contain a specific compound having high maximum temperature or small viscosity as a second component, a specific compound having negative dielectric anisotropy as a third component, and a specific compound having a polymerizable group as an additive component.

    摘要翻译： 一种液晶组合物，其具有至少两种特征，如向列相的最高温度最高，其最低最低温度，小粘度，适当的光学各向异性，大的负介电各向异性，大比电阻，高 对紫外线或热的稳定性和较大的弹性常数; 描述了具有响应时间短，电压保持率大，阈值电压低，对比度大，使用寿命长等特点的AM器件。 液晶组合物具有负的介电各向异性，并且含有具有负的大的介电各向异性和大的弹性常数作为第一成分的特定化合物，并且可以含有作为第二成分的具有最高温度或较小粘度的特定化合物，特定化合物 具有负介电各向异性作为第三成分，具有可聚合基团的具体化合物作为添加成分。

    Substituted chroman-6-yloxy-cycloalkanes and their use as pharmaceuticals
    7.
    发明申请
    Substituted chroman-6-yloxy-cycloalkanes and their use as pharmaceuticals 有权
    取代的苯并二氢吡喃-6-基氧基 - 环烷烃及其作为药物的用途

    公开(公告)号：US20160016928A1

    公开(公告)日：2016-01-21

    申请号：US14772375

    申请日：2014-03-07

    申请人： SANOFI

    发明人： Werngard CZECHTIZKY ,  John WESTON ,  Nils RACKELMANN ,  Volker KRAFT ,  Petra ARNDT ,  Klaus WIRTH ,  Heinz GOEGELEIN ,  Olaf RITZELER

    IPC分类号： C07D311/60 ,  C07D407/14 ,  C07F9/655 ,  C07D405/12

    CPC分类号： C07D311/60 ,  C07D405/12 ,  C07D407/12 ,  C07D407/14 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D417/14 ,  C07F9/65522

    摘要： The present invention relates to substituted chroman-6-yloxy-cycloalkanes of the formula (I) in which Ar, R1 to R4, p and q are as defined in the claims. The compounds of the formula (I) are inhibitors of the sodium-calcium exchanger (NCX), especially of the sodium-calcium exchanger of subtype 1 (NCX1), and are suitable for the treatment of diverse disorders in which intracellular calcium homeostasis is disturbed, such as arrhythmias, heart failure and stroke. The invention furthermore relates to processes for the preparation of the compounds of the formula (I), their use as pharmaceuticals, and pharmaceutical compositions comprising them.

    摘要翻译： 本发明涉及式（I）的取代的苯并二氢吡喃-6-基氧基 - 环烷烃，其中Ar，R 1至R 4，p和q如权利要求中所定义。 式（I）的化合物是钠 - 钙交换剂（NCX）的抑制剂，特别是亚型1型（NCX1）的钠 - 钙交换剂的抑制剂，并且适用于治疗细胞内钙稳态受到干扰的多种疾病 ，如心律失常，心力衰竭和中风。 本发明还涉及制备式（I）化合物，其作为药物的用途以及包含它们的药物组合物的方法。

    FERMENTATION PRODUCT CONTAINING EQUOL-PRODUCING MICROORGANISM HAVING MAINTAINED EQUOL-PRODUCING ABILITY, AND METHOD FOR PRODUCING SAME
    9.
    发明申请
    FERMENTATION PRODUCT CONTAINING EQUOL-PRODUCING MICROORGANISM HAVING MAINTAINED EQUOL-PRODUCING ABILITY, AND METHOD FOR PRODUCING SAME 审中-公开
    含有具有维持生产能力的均质生产微生物的发酵产品及其生产方法

    公开(公告)号：US20150299748A1

    公开(公告)日：2015-10-22

    申请号：US14755550

    申请日：2015-06-30

    申请人： OTSUKA PHARMACEUTICAL CO., LTD.

    发明人： Yoshikazu ISONO ,  Hisako MORI ,  Tomomi UENO ,  Rieko ENDO ,  Megumi KUMEMURA ,  Yasuhiro ABIRU ,  Shigeto UCHIYAMA

    IPC分类号： C12P17/06 ,  C07D311/60

    CPC分类号： C12P17/06 ,  A23C9/1236 ,  A23C9/1315 ,  A23C11/106 ,  A23L11/09 ,  A23L29/065 ,  A23L33/135 ,  A23Y2240/00 ,  C07D311/60

    摘要： An object of the present invention is to provide a fermented product containing equol-producing microorganisms in the state of living cells by which equol production ability is maintained.When producing a fermented material by using an equol-producing microorganism, with soybean powder or soybean milk as raw materials, (1) preparing a mother starter by fermentation under anaerobic conditions by using an equol-producing microorganism in the presence of a daidzein species at pH 5.0 or higher, (2) preparing a bulk starter by fermentation under anaerobic conditions by using said mother starter in the presence of a daidzein species at pH 5.0 or higher, and (3) preparing a fermented material by fermentation by using said bulk starter in a medium containing soybean powder or soybean milk, enables production of a fermented material containing microorganisms in the state of living cells in which the equol production ability is maintained.

    摘要翻译： 本发明的目的在于提供含有维生素生产能力的活细胞状态下的产生雌马酚的微生物的发酵产物。 当使用牛尿酚产生微生物生产发酵物质时，以大豆粉或豆浆为原料，（1）通过在黄豆苷原物质存在下，使用牛尿酚产生微生物在厌氧条件下发酵来制备母发酵剂 pH5.0以上，（2）通过在pH5.0以上的黄豆苷原物质的存在下使用所述母体起始剂在厌氧条件下发酵制备散装起动机，以及（3）通过使用所述批量起动机发酵制备发酵物质 在含有大豆粉末或豆浆的培养基中，能够生产维持雌马酚生产能力的活细胞状态的含有微生物的发酵物质。