公开(公告)号：US20190210949A1

公开(公告)日：2019-07-11

申请号：US16331613

申请日：2017-09-13

Applicant: MARUZEN PETROCHEMICAL CO., LTD.

Inventor： Takashi NANIKI ,  Ryuichi TENJIMBAYASHI ,  Masuo YAMAZAKI ,  Tomohiko SATO

IPC: C07C41/38 ,  C07C43/13 ,  C07C43/16 ,  C07C41/06

CPC classification number: C07C41/38 ,  C07B61/00 ,  C07C41/06 ,  C07C41/08 ,  C07C41/42 ,  C07C43/13 ,  C07C43/16

Abstract: To provide a method capable of easily and efficiently removing a 2-alkoxyethanol from a mixture containing the 2-alkoxyethanol and a (2-alkoxyethyl) vinyl ether while suppressing a decrease in the yield of (2-alkoxyethyl) vinyl ether.A method for removing a 2-alkoxyethanol, including the step of adding one or more azeotropic solvents selected from the group consisting of alkanes having 7 to 8 carbon atoms and cycloalkanes having 7 to 8 carbon atoms to a mixture containing the 2-alkoxyethanol represented by the following formula (1) R—O—CH2CH2OH  (1) where R represents an alkyl group having 1 to 4 carbon atoms, and a (2-alkoxyethyl) vinyl ether represented by the following formula (2) R—O—CH2CH2O—CH═CH2  (2) where R has the same meaning as R in the formula (1), and subjecting the resulting mixture to azeotropic distillation.

公开(公告)号：US09452962B2

公开(公告)日：2016-09-27

申请号：US14129715

申请日：2012-06-28

Applicant: Ralf Pelzer ,  Roland Merten ,  Markus Christian Biel ,  Pierre Fournier

Inventor： Ralf Pelzer ,  Roland Merten ,  Markus Christian Biel ,  Pierre Fournier

IPC: C07C29/44 ,  C07C41/01 ,  C07C41/16 ,  C07C41/08 ,  C07C43/115 ,  C07C41/20 ,  C07C43/178 ,  C07C43/162 ,  C11B9/00 ,  A23L1/226

CPC classification number: C07C43/115 ,  A23L27/203 ,  C07C29/44 ,  C07C41/01 ,  C07C41/08 ,  C07C41/16 ,  C07C41/20 ,  C07C43/162 ,  C07C43/1781 ,  C07C2601/14 ,  C11B9/0034

Abstract: The present invention relates to ethers of 1,2-, 1,3- and 1,4-bis(hydroxymethyl)cyclohexanes, to the preparation of such ethers and also to the use of such ethers as fragrances and as formulation auxiliaries in fragrance-comprising preparations.

Abstract translation: 本发明涉及1,2-，1,3-和1,4-双（羟甲基）环己烷的醚，用于制备这种醚，以及在芳香剂中使用香料和制剂助剂等醚类， 包括制剂。

公开(公告)号：US20100249465A1

公开(公告)日：2010-09-30

申请号：US12729639

申请日：2010-03-23

Applicant: Ryuichi TENJIMBAYASHI ,  Ichiro Kimura

Inventor： Ryuichi TENJIMBAYASHI ,  Ichiro Kimura

IPC: C07C41/42

CPC classification number: C07C41/42 ,  C07C41/08 ,  C07C41/54 ,  C07C43/16 ,  C07C43/188 ,  C07C43/303 ,  C07C43/305 ,  C07C2601/14

Abstract: A process for producing a high-purity vinyl ether, which comprises: a step of subjecting an alcohol represented by the general formula (1) R—O—H  (1) to a vinyl ether formation reaction in the presence of a catalyst to synthesize a vinyl ether represented by the general formula (2), R—O—CH═CH2  (2) a step of removing the catalyst from the reaction mixture obtained in the above step to obtain a crude vinyl ether containing the vinyl ether and the unreacted raw material alcohol, a step of reacting the unreacted raw material alcohol in the crude vinyl ether, with the vinyl ether in the presence of an acid catalyst, to convert the alcohol into an acetal represented by the general formula (3), and a step of subjecting a crude vinyl ether containing the acetal (III) to distillation to obtain a high-purity vinyl ether.

Abstract translation: 一种制备高纯度乙烯基醚的方法，包括：在催化剂存在下使由通式（1）R-O-H（1）表示的醇进行乙烯基醚形成反应的步骤合成 由通式（2）表示的乙烯基醚，R-O-CH = CH 2（2）从上述步骤中获得的反应混合物中除去催化剂以获得含有乙烯基醚的粗乙烯基醚和未反应的步骤 原料醇，在粗乙烯基醚中使未反应的原料醇与乙酸乙烯酯在酸催化剂的存在下反应的步骤，将醇转化为由通式（3）表示的缩醛，以及步骤 将含有缩醛（III）的粗乙烯基醚进行蒸馏以获得高纯度乙烯基醚。

公开(公告)号：US20030114715A1

公开(公告)日：2003-06-19

申请号：US10240683

申请日：2002-10-03

Inventor： Arnd Boettcher ,  Rolf Pinkos ,  Rudolf Erich Lorenz

IPC: C07C041/08 ,  C07C043/20

CPC classification number: C07C41/08 ,  C07C43/16 ,  C07C43/215

Abstract: Alkenyl ethers are prepared by reacting the corresponding alcohols or phenols with acetylenes in the liquid phase in the presence of basic alkali metal compounds and a cocatalyst comprising compounds of the formula (Ia) and/or (Ib)R1Onull(CH2CH2CH2CH2O)nnullHnullnull(Ia)R1Onull(CH2CH2CH2CH2O)nnullH2,nullnull(Ia)where R1, R2 are, independently of one another, C1-C6-alkyl or C2-C6-alkenyl, or R1 and R2 together form a butyl unit and n is 1, 2, 3, 4 or 5.

Abstract translation: 烯化醚通过在碱性碱金属化合物和包含式（Ia）和/或（Ib）R 1 O-（CH 2 CH 2 CH 2 CH 2 O）n H（Ia）的化合物的助催化剂的存在下在液相中与相应的醇或酚反应来制备。 ）R 1 O-（CH 2 CH 2 CH 2 CH 2 O）n -H 2，（Ia）其中R 1，R 2彼此独立地为C 1 -C 6 - 烷基或C 2 -C 6 - 烯基，或者R 1和R 2一起形成丁基单元并且n为1， 2,3,4或5。

公开(公告)号：US06504064B1

公开(公告)日：2003-01-07

申请号：US09884969

申请日：2001-06-21

Applicant: Jochem Henkelmann ,  Heike Becker ,  Juan Aiscar ,  Boris A. Trofimov ,  Nina K. Gusarova ,  Ludmilla A. Oparina

Inventor： Jochem Henkelmann ,  Heike Becker ,  Juan Aiscar ,  Boris A. Trofimov ,  Nina K. Gusarova ,  Ludmilla A. Oparina

IPC: C07C4106

CPC classification number: C07C41/08 ,  C07C43/16

Abstract: Enol ethers of the formula (I) where R1 to R3 are each, independently of one another, hydrogen or a carbon-containing organic radical and R4 is an unsubstituted or substituted alkyl radical, are prepared by reacting alcohols of the formula (II) R4—OH  (II), with alkynes of the formula (IlIa), alkadienes of the formula (IIIb) R1—C≡C—CHR2R3  (IIIa), R1—CH═C═CR2R3  (IIIb) or mixtures thereof, where R1 to R4 are as defined above, in the presence of an alkali metal alkoxide and a polar, aprotic solvent.

Abstract translation: 其中R 1至R 3各自独立地为氢或含碳有机基团且R 4为未取代或取代的烷基的式（I）的烯醇醚通过使式（II）的醇与 在碱金属醇盐和极性非质子溶剂的存在下，式（IIIa）的炔，式（IIIb）的链二烯或其混合物，其中R 1至R 4如上定义。

公开(公告)号：US5726321A

公开(公告)日：1998-03-10

申请号：US620940

申请日：1996-03-22

Applicant: Klaus Bittins ,  Marc Heider ,  Martin Schmidt-Radde ,  Jochen Kellenbenz ,  Kurt Josef Wagner ,  Peter Zehner ,  Stefan Berg

Inventor： Klaus Bittins ,  Marc Heider ,  Martin Schmidt-Radde ,  Jochen Kellenbenz ,  Kurt Josef Wagner ,  Peter Zehner ,  Stefan Berg

IPC: B01J3/00 ,  B01J10/00 ,  C07B61/00 ,  C07C29/36 ,  C07C29/44 ,  C07C29/48 ,  C07C31/12 ,  C07C31/13 ,  C07C31/20 ,  C07C31/27 ,  C07C35/08 ,  C07C41/05 ,  C07C41/08 ,  C07C43/16 ,  C07C51/235 ,  C07C53/122 ,  C07D233/54 ,  C07C31/18 ,  C07C35/18 ,  C07C41/00 ,  C07C43/00

CPC classification number: C07D233/54 ,  B01J10/002 ,  B01J3/00 ,  C07C29/36 ,  C07C29/44 ,  C07C41/08 ,  C07C51/235 ,  B01J2219/00162 ,  C07C2101/14 ,  Y10S585/951

Abstract: Process for carrying out gas/liquid reactions at from (-50.degree.) to 300.degree. C. and from 0.1 to 100 bar by carrying out the reaction in the absence of a continuous gas phase, and, as a special case, a process for the batchwise reaction of acetylene in the liquid phase at from 0.degree. to 300.degree. C. and from 2 to 30 bar, in which acetylene is introduced a) in the absence of a continuous gas phase and b) under isobaric conditions to a degree of saturation of from 5 to 100%.

Abstract translation: 通过在不存在连续气相的情况下进行反应，在（-50℃）〜300℃，0.1〜100巴下进行气/液反应的方法，作为特殊情况， 在不存在连续气相的条件下，在0-300℃和2-30巴条件下将乙炔在液相中进行间歇反应，其中引入乙炔a）a）在不存在连续气相的情况下，和b）在等压条件下以一定程度 饱和度为5〜100％。

公开(公告)号：US5723685A

公开(公告)日：1998-03-03

申请号：US548739

申请日：1995-10-26

Applicant: Marc Heider ,  Thomas Ruhl ,  Herbert Helfert ,  Martin Schmidt-Radde ,  Jochem Henkelmann

Inventor： Marc Heider ,  Thomas Ruhl ,  Herbert Helfert ,  Martin Schmidt-Radde ,  Jochem Henkelmann

IPC: B01J23/02 ,  B01J31/02 ,  B01J31/12 ,  C07B61/00 ,  C07C41/06 ,  C07C41/08 ,  C07C43/178 ,  C07C41/00

CPC classification number: C07C41/08 ,  C07C41/54

Abstract: The preparation of monovinyl ethers of the general formula I ##STR1## in which A stands for a chemical bond or for a methylene or ethylene group, the radicals R.sup.1 and R.sup.2 independently stand for hydrogen, alkyl, cycloalkyl, or aryl groups or R.sup.1 and R.sup.2 together form a C.sub.3 -C.sub.5 alkylene bridging member, by the reaction of a diol of the general formula II ##STR2## in which the variables have the above meanings, with acetylene in the presence of a base, in which the reaction is carried out at 150.degree.-250.degree. C. under an acetylene partial pressure of 5-25 bar until 40-80% of the diol has been converted, at which point the reaction is stopped and the monovinyl ether of the formula I is isolated.

Abstract translation: 制备通式I的单乙烯基醚（I）其中A代表化学键或亚甲基或亚乙基，基团R 1和R 2分别代表氢，烷基，环烷基或芳基或 R 1和R 2一起形成C 3 -C 5亚烷基桥连体，通过其中变量具有上述含义的通式II的二醇（II）与乙炔在碱的存在下反应，其中 反应在150-250℃，乙炔分压为5-25巴下进行，直到二醇的40-80％转化为止，此时反应停止，式I的单乙烯基醚 是孤立的

公开(公告)号：US5183946A

公开(公告)日：1993-02-02

申请号：US852421

申请日：1992-03-16

Applicant: Kou-Chang Liu ,  Paul D. Taylor

Inventor： Kou-Chang Liu ,  Paul D. Taylor

IPC: C07C41/08 ,  C07C43/178

CPC classification number: C07C41/08 ,  C07C2101/14 ,  C07C2101/18

Abstract: The invention relates to a vinyloxy hydroxyalkyl cycloalkylene having the formulaHO(CH.sub.2).sub.x --A--(CH.sub.2).sub.x, OCH.dbd.CH.sub.2wherein x has a value of from 1 to 10; x' has a value of from 0 to 10 and A is a cycloalkylene group having from 3 to 8 carbon atoms in the ring and is optionally substituted with lower alkyl. The invention also relates to the method for synthesizing the above compounds.

Abstract translation: 本发明涉及具有式HO（CH 2）x -A-（CH 2）x，OCH = CH 2的乙烯基氧基羟基烷基亚环烷基，其中x具有1至10的值; x'具有0至10的值，并且A是在环中具有3至8个碳原子的亚环烷基，并且任选被低级烷基取代。 本发明还涉及上述化合物的合成方法。

公开(公告)号：US09981897B2

公开(公告)日：2018-05-29

申请号：US15211247

申请日：2016-07-15

Applicant: BASF SE

Inventor： Ralf Pelzer ,  Roland Merten ,  Pierre Fournier ,  Markus C. Biel

IPC: C07C43/115 ,  C07C29/44 ,  C07C41/01 ,  C07C41/16 ,  C11B9/00 ,  C07C41/20 ,  C07C43/162 ,  C07C43/178 ,  C07C41/08 ,  A23L27/20

CPC classification number: C07C43/115 ,  A23L27/203 ,  C07C29/44 ,  C07C41/01 ,  C07C41/08 ,  C07C41/16 ,  C07C41/20 ,  C07C43/162 ,  C07C43/1781 ,  C07C2601/14 ,  C11B9/0034

Abstract: The present invention relates to ethers of 1,2-, 1,3- and 1,4-bis(hydroxymethyl)cyclohexanes, to the preparation of such ethers and also to the use of such ethers as fragrances and as formulation auxiliaries in fragrance-comprising preparations.

公开(公告)号：US09758499B2

公开(公告)日：2017-09-12

申请号：US15398094

申请日：2017-01-04

Applicant: The Florida State University Research Foundation, Inc.

Inventor： Dinesh V. Vidhani ,  Marie E. Krafft ,  Igor Alabugin

IPC: C07D307/46 ,  C07C41/08 ,  C07C45/51 ,  C07C253/30 ,  C07D307/42

CPC classification number: C07D307/46 ,  C07C41/08 ,  C07C45/513 ,  C07C253/30 ,  C07D307/42 ,  C07C255/56 ,  C07C255/54 ,  C07C47/21 ,  C07C43/16 ,  C07C43/164 ,  C07C43/162 ,  C07C47/232 ,  C07C47/225

Abstract: A novel Rh(I)-catalyzed approach to synthesizing functionalized (E,Z) dienal compounds has been developed via tandem transformation where a stereoselective hydrogen transfer follows a propargyl Claisen rearrangement. Z-Stereochemistry of the first double bond suggests the involvement of a six-membered cyclic intermediate whereas the E-stereochemistry of the second double bond stems from the subsequent protodemetallation step giving an (E,Z)-dienal. The reaction may be represented by the following sequence.