POLYPEPTIDE MONOLAYER WITH LOW POTENTIAL AND HYDROPHOBICITY, AND PREPARATION METHOD AND APPLICATION

    公开(公告)号:US20230142745A1

    公开(公告)日:2023-05-11

    申请号:US17753424

    申请日:2020-11-27

    摘要: A polypeptide monolayer with a low surface potential and hydrophobicity. The polypeptide is composed of polypeptide molecules with a molecular weight of (1.48±0.2)×105 g/mol, a thickness of the monolayer is 6.2-9.0 nm, the exposure of primary amino groups on the surface of the monolayer is 9.5-15%, a Zeta potential of the polypeptide monolayer is (−3)−(−9) mV, and a contact angle of the monolayer is (61±1°)-(84±1°). The monolayer can be ultrathin, with a minimum thickness of only about 6.6 nm. The polypeptide monolayer can also be applied to the preparation of a biosensor, which is conductive to increase in limit of detection. The content of primary amino groups on the surface of polypeptide monolayer is conductive to controllability of further chemical modification and laying the foundation for achieving controllable grafting of polysiloxane and biological preparations in the later stage.

    METHOD FOR COATING METAL SURFACES USING AN AQUEOUS COMPOUND HAVING POLYMERS, THE AQUEOUS COMPOUND, AND USE OF THE COATED SUBSTRATES
    10.
    发明申请
    METHOD FOR COATING METAL SURFACES USING AN AQUEOUS COMPOUND HAVING POLYMERS, THE AQUEOUS COMPOUND, AND USE OF THE COATED SUBSTRATES 审中-公开
    使用具有聚合物的水性化合物,水性化合物和涂覆的基材的使用来涂覆金属表面的方法

    公开(公告)号:US20140134368A1

    公开(公告)日:2014-05-15

    申请号:US14156720

    申请日:2014-01-16

    申请人: Chemetall GmbH

    摘要: The invention concerns a process for coating a metallic surface with an aqueous composition, wherein in addition to water the composition contains a) as the main component, an organic film former consisting of at least one synthetic resin, 70 to 100 wt. % of the content of synthetic resin(s) in the organic film former comprising at least one water-soluble or/and water-dispersible synthetic resin in the form of polymers, copolymers, block copolymers or/and graft copolymers based on synthetic resins selected from the group consisting of polycarbonate, polyurethane, ionomer, poly(meth)acrylate, polyester, polyether or/and polystyrene, the content of polycarbonate and polyurethane being at least 10 wt. % each, b) at least one long-chain alcohol as film-forming aid for the organic film former, c) at least one crosslinker, d) at least one lubricant, and e) at least one substance based on silane, silanol or/and siloxane or/and at least one inorganic compound in particle form with an average particle diameter measured on a scanning electron microscope in the range from 0.005 to 0.3 μm, and f) optionally at least one organic corrosion inhibitor, at least one organic solvent or/and at least one additive, wherein the metallic surface is brought into contact with the aqueous composition and a polymeric film is formed on the metallic surface with a film thickness in the range from 0.01 to 10 μm. The invention also concerns a corresponding aqueous composition.

    摘要翻译: 本发明涉及一种用水性组合物涂覆金属表面的方法,其中除了水之外,组合物含有a)作为主要成分,由至少一种合成树脂组成的有机成膜剂为70-100wt。 基于合成树脂选择的聚合物,共聚物,嵌段共聚物或/和接枝共聚物形式的至少一种水溶性或/和水分散性合成树脂的有机成膜剂中合成树脂的含量的百分比 由聚碳酸酯,聚氨酯,离聚物,聚(甲基)丙烯酸酯,聚酯,聚醚或/和聚苯乙烯组成的组中,聚碳酸酯和聚氨酯的含量为至少10重量% %),b)至少一种长链醇作为有机成膜剂的成膜助剂,c)至少一种交联剂,d)至少一种润滑剂,和e)至少一种基于硅烷,硅烷醇或 /和硅氧烷或/和至少一种颗粒形式的无机化合物,其平均粒径在扫描电子显微镜上测量的范围为0.005-0.3μm,和f)任选的至少一种有机腐蚀抑制剂,至少一种有机溶剂 或/或至少一种添加剂,其中金属表面与含水组合物接触,并且在金属表面上形成膜厚在0.01至10μm范围内的聚合物膜。 本发明还涉及相应的水性组合物。