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公开(公告)号:US09528083B2
公开(公告)日:2016-12-27
申请号:US15017354
申请日:2016-02-05
IPC分类号: C12N5/10 , C12M1/00 , B01F3/04 , B01F7/16 , B01F7/18 , B01F15/00 , C12M1/06 , C12M1/12 , B01D47/05 , C12N1/10 , C12N1/12 , C12N1/14 , C12N1/20 , C12N5/00 , C12N5/04 , B01D5/00 , B01F7/00 , B01F15/06
CPC分类号: C12M23/14 , B01D5/0072 , B01D47/05 , B01F3/04241 , B01F3/04531 , B01F7/00691 , B01F7/1695 , B01F7/18 , B01F7/22 , B01F15/00071 , B01F15/00831 , B01F15/0085 , B01F15/065 , B01F2003/04191 , B01F2003/04297 , B01F2003/04673 , B01F2003/04865 , B01F2003/04872 , B01F2003/04879 , B01F2003/04893 , B01F2003/04921 , B01F2015/061 , B01F2215/0073 , C12M23/26 , C12M23/34 , C12M27/02 , C12M29/00 , C12M29/06 , C12M29/24 , C12M37/00 , C12M41/14 , C12M41/18 , C12N1/10 , C12N1/12 , C12N1/14 , C12N1/20 , C12N5/00 , C12N5/04 , C12N5/10 , F28B1/02 , F28F3/12 , F28F21/06 , F28F2255/02
摘要: A heat exchanger system includes a heat exchanger having a body with a first side face and an opposing second side face, the body bounding a fluid channel disposed between the opposing side faces and extending between an inlet port and an outlet port. A flexible first bag has of one or more sheet of polymeric material and bounds a fluid pathway that extends between a fluid inlet and a fluid outlet. The first bag is removably retained against the first side face of the body of the heat exchanger, the fluid channel of the body of the heat exchanger being sealed from fluid communication with the fluid pathway of the first bag.
摘要翻译: 热交换器系统包括具有主体的热交换器,该主体具有第一侧面和相对的第二侧面,该主体包围设置在相对侧面之间并在入口和出口之间延伸的流体通道。 柔性第一袋具有一个或多个聚合物材料片并且限定了在流体入口和流体出口之间延伸的流体路径。 第一袋可移除地保持在热交换器的主体的第一侧面上,热交换器的主体的流体通道与第一袋的流体通道的流体连通密封。
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公开(公告)号:US08800608B2
公开(公告)日:2014-08-12
申请号:US13661398
申请日:2012-10-26
IPC分类号: B65B31/00
CPC分类号: B65B1/04 , A61J1/10 , A61J1/16 , A61J1/20 , A61J3/002 , B01F9/0016 , B01F9/002 , B01F9/0023 , B01F13/1055 , B01F13/1069 , B01F15/00071 , B01F15/00746 , B01F2009/0072 , B01F2009/0081 , B01F2015/00097 , B01F2215/0032 , B65B43/46 , B65B43/465
摘要: A machine for the preparation of pharmaceutical products is provided with a gripping and carrier device to transfer at least one container between a magazine and a dosage station for the preparation of a pharmaceutical product, and a box-type holding frame defining a chamber for the housing of magazine, gripping and carrier device, and dosage station; the chamber displaying an access aperture to magazine and being crossed by a sterile air flow adapted to avoid the entry of air from the external environment through aperture itself.
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公开(公告)号:US20130192165A1
公开(公告)日:2013-08-01
申请号:US13661398
申请日:2012-10-26
IPC分类号: B65B1/04
CPC分类号: B65B1/04 , A61J1/10 , A61J1/16 , A61J1/20 , A61J3/002 , B01F9/0016 , B01F9/002 , B01F9/0023 , B01F13/1055 , B01F13/1069 , B01F15/00071 , B01F15/00746 , B01F2009/0072 , B01F2009/0081 , B01F2015/00097 , B01F2215/0032 , B65B43/46 , B65B43/465
摘要: A machine for the preparation of pharmaceutical products is provided with a gripping and carrier device to transfer at least one container between a magazine and a dosage station for the preparation of a pharmaceutical product, and a box-type holding frame defining a chamber for the housing of magazine, gripping and carrier device, and dosage station; the chamber displaying an access aperture to magazine and being crossed by a sterile air flow adapted to avoid the entry of air from the external environment through aperture itself.
摘要翻译: 一种用于制备药物的机器设置有夹持和载体装置,用于在用于制备药物产品的药盒和剂量站之间转移至少一个容器,以及限定用于外壳的腔室的盒式保持框架 杂志,夹持和载体装置和剂量站; 该腔室显示出杂物的进入孔,并被无菌空气流穿过,以避免通过孔本身从外部环境进入空气。
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公开(公告)号:US08297320B2
公开(公告)日:2012-10-30
申请号:US12374875
申请日:2006-12-07
IPC分类号: B65B31/00
CPC分类号: B65B1/04 , A61J1/10 , A61J1/16 , A61J1/20 , A61J3/002 , B01F9/0016 , B01F9/002 , B01F9/0023 , B01F13/1055 , B01F13/1069 , B01F15/00071 , B01F15/00746 , B01F2009/0072 , B01F2009/0081 , B01F2015/00097 , B01F2215/0032 , B65B43/46 , B65B43/465
摘要: A machine for the preparation of pharmaceutical products is provided with a gripping and carrier device to transfer at least one container between a magazine and a dosage station for the preparation of a pharmaceutical product, and a box-type holding frame defining a chamber for the housing of magazine, gripping and carrier device, and dosage station; the chamber displaying an access aperture to magazine and being crossed by a sterile air flow adapted to avoid the entry of air from the external environment through aperture itself.
摘要翻译: 一种用于制备药物的机器设置有夹持和载体装置,用于在用于制备药物产品的药盒和剂量站之间转移至少一个容器,以及限定用于外壳的腔室的盒式保持框架 杂志,夹持和载体装置和剂量站; 该腔室显示出杂物的进入孔,并被无菌空气流穿过,以避免通过孔本身从外部环境进入空气。
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公开(公告)号:US20110249526A1
公开(公告)日:2011-10-13
申请号:US13043862
申请日:2011-03-09
申请人: Dennis Wong
发明人: Dennis Wong
IPC分类号: B01F15/00
CPC分类号: C12M41/00 , B01F7/162 , B01F13/08 , B01F15/00071 , B01F15/00175 , B01F15/00207 , B01F15/0022 , B01F15/00227 , B01F15/00831 , B01F15/0085 , B01L3/52 , C12M23/14 , C12M23/26 , C12M27/02
摘要: A process bag container is provided comprising a flexible bag, at least one inlet sealed to the bag, and an outlet. A probe housing for a probe construction is sealed to the bag. Preferably, the probe housing extends at least partway into the bag interior and is connected to a cable for power and data transmission that runs along the outer surface of the bag to the top of the bag or its support container. The probe construction is adapted to monitor the composition of a reagent in the bag as well as the environment within the bag. A mixer is positioned within the bag to effect mixing of reagents in the bag.
摘要翻译: 提供一种处理袋容器,其包括柔性袋,至少一个入口密封到袋和出口。 用于探针结构的探针壳体被密封到袋子上。 优选地,探针壳体至少部分地延伸到袋内部,并且连接到沿着袋的外表面延伸到袋或其支撑容器的顶部的电力和数据传输的电缆。 探针结构适于监测袋中的试剂的组成以及袋内的环境。 将混合器定位在袋内以实现袋中试剂的混合。
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公开(公告)号:US20110058447A1
公开(公告)日:2011-03-10
申请号:US12991461
申请日:2009-05-07
申请人: Oscar-Werner Reif , Gerhard Greller , Juergen Van Den Boogaard , Sven Luehmann , Marco Lohrengel
发明人: Oscar-Werner Reif , Gerhard Greller , Juergen Van Den Boogaard , Sven Luehmann , Marco Lohrengel
IPC分类号: B01F7/16
CPC分类号: C12M23/14 , B01F7/1695 , B01F13/0827 , B01F13/0836 , B01F15/00071 , B01F15/00831 , B01F15/0085 , B01F2015/00084 , B01F2215/0032 , B01F2215/0073 , C12M27/02
摘要: A mixing system has a container with flexible walls (1), a fluid-tight drive space (6) and a mixing device. The container with flexible walls (1) has at least one head plate (5). The fluid-tight drive space (6) is outside of the container interior (2), and is enclosed by the head plate (5) and a cap (7) attached to the head plate (5). The mixing device has a stirrer shaft (3), onto which stirrer elements (4, 4′) are attached. The stirrer shaft (3) is guided from the container interior (2) through an opening in the head plate (5) and the section of the stirrer shaft (3) in the drive space (6) is guided by bearings (9, 10). A seal (8) is fit into the opening of the head plate, and encloses the stirrer shaft (3) and seals the container interior (2) from the drive space (6).
摘要翻译: 混合系统具有容器,该容器具有柔性壁(1),流体密封的驱动空间(6)和混合装置。 具有柔性壁(1)的容器具有至少一个头板(5)。 流体密封的驱动空间(6)位于容器内部(2)的外部,并由头板(5)和盖(7)封闭,盖帽(7)附接到头板(5)。 混合装置具有搅拌器轴(3),搅拌器元件(4,4')安装在搅拌轴上。 搅拌器轴(3)从容器内部(2)通过头板(5)中的开口引导,并且驱动空间(6)中的搅拌器轴(3)的部分由轴承(9,10 )。 密封件(8)装配在头板的开口中,并包围搅拌器轴(3)并将容器内部(2)与驱动空间(6)密封。
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公开(公告)号:US20070053238A1
公开(公告)日:2007-03-08
申请号:US11219738
申请日:2005-09-07
申请人: Anthony Kocienski
发明人: Anthony Kocienski
IPC分类号: B01F13/08
CPC分类号: B01F15/00915 , B01F7/186 , B01F13/0863 , B01F15/00071 , B01F2215/0032
摘要: A mixing apparatus and method uses a disposable assembly including a closed vessel with a rotating shaft supported in the vessel. The shaft has radially extending impellers. The shaft is driven via an external magnetic drive system. The vessel can be cleaned during manufacture and discarded after use.
摘要翻译: 混合装置和方法使用一次性组件,其包括具有支撑在容器中的旋转轴的密闭容器。 轴具有径向延伸的叶轮。 轴通过外部磁驱动系统驱动。 容器在制造过程中可以清洗,使用后丢弃。
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公开(公告)号:US20050249033A1
公开(公告)日:2005-11-10
申请号:US10838576
申请日:2004-05-04
申请人: Richard Krause
发明人: Richard Krause
IPC分类号: B01F11/00
CPC分类号: B01F11/0082 , B01F15/00071 , B01F15/00831 , B01F15/0085 , B01F2215/0032 , B01F2215/0073
摘要: A (disposable) single-use closed mixing system consisting of a mixing impeller(s) on a shaft, the shaft being sealed to the top of the bag. The flexible bag is used as the reciprocating membrane. Bag sizes 1 to 10,000 liters, can be gamma sterilized or non-sterile. The bags can be round or square in shape. All components including the impeller, shaft and accessories are CLASS VI material. The impeller or impellers used for large bags can be round, or square with holes, flutes, fins, tubing or a combination of these to meet specific mixing requirements. A detachable electric or air powered actuator provides the reciprocating action. The impeller shaft is sealed to the bag eliminating the need for rotary seals. Disposal of the mixing system is environmentally friendly.
摘要翻译: 一种(一次性)一次性密闭混合系统,由轴上的混合叶轮组成,轴被密封到袋的顶部。 柔性袋用作往复式膜。 袋子尺寸为1至10,000升,可以进行γ灭菌或非灭菌。 袋子可以是圆形或正方形。 包括叶轮,轴和附件在内的所有部件都是CLASS VI材料。 用于大袋的叶轮或叶轮可以是圆形的,或具有孔,槽,翅片,管道或这些的组合的正方形,以满足特定的混合要求。 可拆卸的电动或空气致动器提供往复动作。 叶轮轴密封到袋子上,无需旋转密封。 混合系统的处理是环保的。
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公开(公告)号:US20020105856A1
公开(公告)日:2002-08-08
申请号:US10068373
申请日:2002-02-05
发明人: Alexandre Terentiev
IPC分类号: B01F007/16
CPC分类号: B01F7/00325 , B01F7/0005 , B01F7/1695 , B01F15/00071 , B01F15/00824 , B01F15/0085 , B01F15/0212 , B01F2015/00084 , B01F2215/0037 , B01F2215/0073 , C12M23/14 , C12M27/02
摘要: A mixing bag usable in chemical and bioprocessing procedures that is hermetically sealed about a tube that is closed within the bag but extends out through a seal and adapted to receive a rotatable rigid rod of a predetermined shape for mixing the materials in the bag.
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公开(公告)号:US09738862B2
公开(公告)日:2017-08-22
申请号:US14441009
申请日:2013-11-06
发明人: Yrjo Virtanen , Vesa Joutsjoki
CPC分类号: C12M27/02 , B01F7/00975 , B01F7/16 , B01F15/00071 , B01F15/00175 , B01F15/00389 , B01F15/00396 , B01F15/00545 , B01F15/00662 , B01F15/00785 , B01F15/06 , B01F15/066 , B01F2015/062 , B01F2215/0073 , B01F2215/0431 , B01F2215/0472 , C12M23/38 , C12M23/44 , C12M29/00 , C12M41/24
摘要: A bioreactor apparatus includes a vessel establishing an interior space environmentally separable from an exterior space outside of the vessel, an agitation system including mixing means arranged in the interior space and drive means adapted to rotate the mixing means. The drive means includes a drive motor that is arranged in the interior space.
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