Tangential Filtration Elements and Filtration Devices and Methods Of Use

    公开(公告)号:US20240299885A1

    公开(公告)日:2024-09-12

    申请号:US18531697

    申请日:2023-12-07

    申请人: Yingqing Huang

    发明人: Yingqing Huang

    摘要: In some embodiments thereof, the present invention describes TFF (Tangential Flow Filtration) filtration devices that utilize tubular membranes for the separation of cells and particles. These devices encompass several innovative features, including the use of membrane tubes with either circular or non-circular cross-sections. These tubes are closely surrounded by both tube housing and filter housing to regulate the pressure of the liquid exiting the filter housing. Additionally, the membrane tubes may feature internal cores within their lumens and/or structures along their inner walls. These internal features serve to regulate flow patterns and pressures within the tubes. One notable aspect of this invention is the inclusion of features on the tube housing or tube core that effectively regulate pressure resistance and feed flow patterns. These features lead to a reduction in the required recirculation rate and contribute to improved transmembrane pressure profiles, making these membrane filters highly effective for cell retention in cell culture and other applications. The patent also introduces various filter designs that incorporate tubular membranes into TFF filtration devices to achieve multiple goals, including a more consistent TMP (Transmembrane Pressure) profile for efficient separation, reduced recirculation rates to generate adequate shear rates, higher packing densities of membrane surface areas within the same filter design, and enhanced manufacturability and recyclability of the filters. Overall, this invention represents a significant advancement in the field of TFF filtration, offering innovative solutions for a wide range of applications in the separation of cells and particles.

    ASSEMBLY INCLUDING SERIALLY CONNECTED SPIRAL WOUND MODULES WITH PERMEATE FLOW CONTROLLER
    6.
    发明申请
    ASSEMBLY INCLUDING SERIALLY CONNECTED SPIRAL WOUND MODULES WITH PERMEATE FLOW CONTROLLER 审中-公开
    组装包括带有渗透流量控制器的串联连接螺旋缠绕模块

    公开(公告)号:US20160129398A1

    公开(公告)日:2016-05-12

    申请号:US14774023

    申请日:2014-04-15

    IPC分类号: B01D63/12

    摘要: A spiral wound assembly including: i) a pressure vessel including a feed inlet, concentrate outlet and permeate outlet, and ii) a plurality of spiral wound modules, each including at least one membrane envelop wound around a permeate tube, and wherein the spiral wound modules are serially arranged within the pressure vessel with a first element of the series positioned adjacent to a first end of the pressure vessel and a last element of the series positioned adjacent to an opposing second end of the pressure vessel, and wherein the permeate tubes of the spiral wound elements are serially connected to form a permeate pathway which is connected to the permeate outlet. The assembly is characterized by including a flow controller within the permeate pathway that provides a resistance that varies as a function of permeate flow.

    摘要翻译: 一种螺旋缠绕组件,包括:i)包括进料入口,浓缩物出口和渗透物出口的压力容器,以及ii)多个螺旋缠绕模块,每个包括缠绕在渗透管周围的至少一个膜包膜,并且其中所述螺旋缠绕 模块串联设置在压力容器内,其中串联的第一元件邻近压力容器的第一端定位,并且该系列的最后一个元件邻近压力容器的相对的第二端定位,并且其中渗透管 螺旋缠绕元件串联连接以形成渗透通道,其连接到渗透物出口。 该组件的特征在于在渗透通路内包括一个流量控制器,该流量控制器提供作为渗透物流量的函数而变化的阻力。

    SPIRAL TYPE SEAWATER DESALINATION APPARATUS
    7.
    发明申请
    SPIRAL TYPE SEAWATER DESALINATION APPARATUS 审中-公开
    螺旋式海水淡化装置

    公开(公告)号:US20160038882A1

    公开(公告)日:2016-02-11

    申请号:US14825499

    申请日:2015-08-13

    IPC分类号: B01D63/12 C02F1/44 B01D61/02

    摘要: An embodiment of the present invention includes: a spiral type pressure vessel 15 in which a plurality of reverse osmosis membrane apparatuses 13-1 to 13-10 having spiral reverse osmosis membranes is connected through a permeated water pipe 14, and is housed in a connected state; a raw water supplying line that supplies raw water 11 into the pressure vessel 15; a concentrated water discharging line through which concentrated water 16 concentrated is discharged; a plug 17 that blocks the permeated water pipe 14 at the center of the reverse osmosis membrane apparatuses 13-1 to 13-10; a front-side permeated water line and a front-side permeated water line through which front-side permeated water 12-1 and rear-side permeated water 12-2 are discharged to the exterior, respectively, which are separated fore and aft, respectively, of the permeated water pipe 14 blocked by the plug 17; a pressure regulating valve 20 that is mounted in the raw water supplying line and regulates the supply pressure of the raw water 11; and a flow regulating valve 22 that is mounted in the front-side permeated water line and regulates the pressure of the front-side permeated water 12-1.

    摘要翻译: 本发明的一个实施例包括:螺旋型压力容器15,其中多个具有螺旋反渗透膜的反渗透膜装置13-1至13-10通过渗透水管14连接,并且被容纳在连接 州; 将原水11供给到压力容器15内的原水供给管路; 浓缩水16集中排出的浓缩排水管线; 堵塞反渗透膜装置13-1〜13-10的中央处的渗透水管14的塞子17; 前侧渗透水线和前侧渗透水线,前侧渗透水12-1和后侧渗透水12-2分别通过其分别前后分别排出到外部,前侧渗透水线 由插头17阻塞的透水水管14; 压力调节阀20,其安装在原水供给管线中并调节原水11的供给压力; 以及流量调节阀22,其安装在前侧渗透水管路中并调节前侧渗透水12-1的压力。

    Methods of Making a Hollow Fiber Membrane Element Adapted for use in Water Treatment and Osmotic Processes
    8.
    发明申请
    Methods of Making a Hollow Fiber Membrane Element Adapted for use in Water Treatment and Osmotic Processes 审中-公开
    制造适用于水处理和渗透过程的中空纤维膜元件的方法

    公开(公告)号:US20150157983A1

    公开(公告)日:2015-06-11

    申请号:US14593777

    申请日:2015-01-09

    IPC分类号: B01D63/02

    摘要: A membrane element comprising: a hollow fiber (HF) stack comprising a plurality of loosely packed hollow fibers (HFs) comprising first ends extending through one contact structure and opposed ends extending through an opposed contact structure, each HF comprising an elongated lumen extending between the one contact structure and the opposed contact structure and comprising a hydrophilic semipermeable membrane adapted to achieve salt rejection of 98.5% or more and exhibiting a surface tension of 35 dynes/cm or more; the membrane element being adapted to be encased in a frame and submersed in a first fluid and for induced osmosis between lumens of the plurality of loosely packed HFs and the first fluid, the membrane element having sufficient mechanical integrity when encased in the frame and submersed in the first fluid to sustain turbulence flow across and along surfaces of the plurality of loosely packed HFs at a Reynolds' Number of about 3,000 or more and to maintain said mechanical integrity at feed pumping pressures of 30 bars or higher.

    摘要翻译: 一种膜元件,包括:包含多个松散包装的中空纤维(HF)的中空纤维(HF)堆叠,其包括延伸穿过一个接触结构的第一端和延伸穿过相对接触结构的相对端,每个HF包括在 一个接触结构和相对的接触结构,并且包括适于实现98.5%或更高的盐排斥并且表现出35达因/厘米或更大的表面张力的亲水半透膜; 膜元件适于包封在框架中并浸没在第一流体中,并且用于多个松散包装的HF和第一流体的流体之间的诱导渗透,当包装在框架中并浸没在膜元件中时,膜元件具有足够的机械完整性 维持湍流的第一流体以大约3,000或更大的雷诺数来流过和沿着多个松散包装的HF的表面流动并且在30巴或更高的进料泵送压力下保持所述机械完整性。

    Method for reducing performance variability of multi-layer filters
    10.
    发明授权
    Method for reducing performance variability of multi-layer filters 有权
    降低多层滤波器性能变异性的方法

    公开(公告)号:US08733556B2

    公开(公告)日:2014-05-27

    申请号:US12387576

    申请日:2009-05-05

    摘要: Multi-layer membrane devices with reduced performance variability, and method of reducing performance variability of such devices. The variability is reduced by combining two or more membranes with similar pore sizes, and carefully selecting the upstream membrane based upon its performance rating, in order to control the performance of the overall device. Selective layering reduces the capacity range of the device when compared to random layering, with the mean capacity greater than overall population mean. The flux range also can be reduced, with the mean near the overall population mean. The LRV range also can be reduced, with the mean LRV near or higher than the overall population mean.

    摘要翻译: 具有降低的性能变异性的多层膜装置,以及降低这些装置的性能变异性的方法。 通过组合具有相似孔径的两个或更多个膜,并且基于其性能等级仔细选择上游膜,以便控制整个装置的性能来降低可变性。 与随机分层相比,选择性分层降低了设备的容量范围,平均容量大于总体平均数。 通量范围也可以减少,平均值接近总体平均值。 LRV范围也可以减少,平均LRV接近或高于总体人口平均值。