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公开(公告)号：US20240108818A1
公开(公告)日：2024-04-04
申请号：US18276627
申请日：2022-02-15
申请人： Novo Nordisk A/S
CPC分类号： A61M5/3298 , A61M5/20 , A61M5/2459 , A61M5/31581 , A61M5/3204 , A61M5/3271 , A61M5/3293 , A61M2005/2013 , A61M2005/206 , A61M2005/208
摘要： A drug delivery device (100, 300), comprising a rotatable drum (210, 410) with a plurality of needle assemblies, a shield (110, 410) and a needle change mechanism (134, 233, 105.2, 231, 105.2, 214, 305.1, 317). The needle change mechanism is operationally coupled to the drum (210, 410) and the shield (110, 310). The needle change mechanism is having an active state adapted to induce rotation of the drum (210, 410), in response to a movement of the shield (110, 310), the needle change mechanism further comprises a passive state wherein no rotation is induced on the drum (210, 410). The needle change mechanism is, in response to the second movement of the shield (110, 310), adapted to change from the passive state to the active state after the hollow needle (224, 424) disconnects from the cartridge, whereby it is prevented that the drum (210, 410) rotates while the hollow needle (224, 424) is connected with the cartridge.
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公开(公告)号：US20240033446A1
公开(公告)日：2024-02-01
申请号：US18257487
申请日：2021-12-14
CPC分类号： A61M5/3298 , A61M39/10 , A61M5/2466 , A61M5/322
摘要： A needle assembly configured to be part of a drug delivery device comprises a plurality of extendable and retractable needles. The needles are fluidly coupled by a flexible connector, which is configured to maintain fluid connection between the needles throughout their movement. When the needles are extended, a first needle pierces a patient's skin, and a second needle pierces a septum of a drug container to deliver a medication. Once the medication has been delivered, the needles may then retract within a needle assembly housing. The needle assembly may also be part of a partially disposable drug delivery device and may be used with multiple different drug cartridges. Multiple embodiments of the needle assembly are disclosed.
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公开(公告)号：US20180272078A1
公开(公告)日：2018-09-27
申请号：US15730541
申请日：2017-10-11
CPC分类号： A61M5/3298 , A61B6/508 , A61M5/1452 , A61M5/14526 , A61M5/16827 , A61M5/20 , A61M5/3287 , A61M5/3291 , A61M5/3294 , A61M2205/50 , A61M2205/52
摘要： A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality, of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment.
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公开(公告)号：US20180078714A1
公开(公告)日：2018-03-22
申请号：US15690111
申请日：2017-08-29
发明人： Hiroshi OZAWA , Akinori INOU , Nobuyuki TAKAHASHI , Akihiro SHINODA , Eiji KANI
CPC分类号： A61M5/3298 , A61M5/345 , A61M5/349
摘要： An injection needle is provided that allows design of the size of a needle base without being limited by the size of a syringe connecting part. As a hub, a needle base that is formed to have a through hole into which a needle tube is inserted, and a tubular housing where both ends in the axial direction are opened and the needle base is fitted and stored inside of one end, are formed as separate injection molded parts, thereby allowing the needle base to be largely designed. A needle tube shield part is in a box-lid shape, and the back side of a ceiling part thereof is provided with a tubular guiding part. An edge surface thereof abuts on the needle base, and a side part annularly holds and abuts on the housing. Accordingly, the needle base does not move upon receiving the pressure of a drug solution.
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公开(公告)号：US20170258507A1
公开(公告)日：2017-09-14
申请号：US15608861
申请日：2017-05-30
申请人： Hugh Hetherington
发明人： Hugh Hetherington
CPC分类号： A61B17/8822 , A61B5/0002 , A61B2017/00747 , A61B2017/00792 , A61M5/20 , A61M5/24 , A61M5/31505 , A61M5/31511 , A61M5/31576 , A61M5/31578 , A61M5/3158 , A61M5/31585 , A61M5/3287 , A61M5/3298 , A61M5/482 , A61M2005/2073 , A61M2005/3152
摘要： A single hand operable injection control device (ICD) automatically injects material into a subject tissue at a rate controllably proportional to the rate of movement of the syringe. Squeezing the figure holds rotates a transmission/timing belt that is connected to a position reference member/guide that pushes against the subject tissue, causing the ICD body (containing the syringe) to push away from the subject tissue. The timing belt turns a worm gear that drives a syringe plunger into the syringe held by the ICD. The coordinated motions result in precise delivery of a unit volume/region of injectate into the subject. That is, a uniform “tube” of injectate is automatically laid in the cannula track.
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公开(公告)号：US20170157337A1
公开(公告)日：2017-06-08
申请号：US15435433
申请日：2017-02-17
发明人： Ilona Eggert , Frederic Laugere , Cristian Popa , Ben Impey , Andrew Macleod
CPC分类号： A61M5/343 , A61M5/19 , A61M5/2448 , A61M5/2455 , A61M5/3294 , A61M5/3295 , A61M5/3298 , A61M39/22 , A61M39/223 , A61M2005/3128 , A61M2205/12 , A61M2205/121 , A61M2207/00
摘要： The invention inter alia relates to a dispense interface for an ejection device. The dispense interface comprises at least two inlets, at least one outlet, a body part, and a fluid channel arrangement within the body part configured to provide fluid communication between the at least two inlets and the at least one outlet; wherein each of the at least two inlets is formed from a tubelike fluid element; wherein each of the tubelike fluid elements is molded into the body part; and wherein each of the tubelike fluid elements provides at least a part of the fluid channel arrangement within said body part.
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公开(公告)号：US20170157327A1
公开(公告)日：2017-06-08
申请号：US15115961
申请日：2014-12-23
申请人： PANACE CO., LTD.
发明人： Sung Tae YOON
CPC分类号： A61M5/2053 , A61M5/20 , A61M5/3298 , A61M5/425 , A61M2205/3344
摘要： The present invention uses an injection apparatus comprising: an injector which includes a mounting part on which a syringe is mounted, a needle assembly having a plurality of needles, a motor and a screw for actuating a piston of the syringe forward and backward; and a main body for controlling the forward and backward actuation of the piston of the syringe and drug injection. The present invention is configured as follows: a vacuum suction pressure is formed in the needle assembly that is in contact with the skin; injection is performed so that a drug is injected through a needle after it is determined that the needle is in close contact with the skin by comparing a sensed vacuum suction pressure value with a preset vacuum suction pressure value; and if injection is completed, the needle assembly is separated from the skin.
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公开(公告)号：US09662457B2
公开(公告)日：2017-05-30
申请号：US13261780
申请日：2012-06-01
CPC分类号： A61M5/3294 , A61M5/1782 , A61M5/19 , A61M5/2448 , A61M5/2466 , A61M5/31511 , A61M5/3202 , A61M5/326 , A61M5/3272 , A61M5/3287 , A61M5/3293 , A61M5/3298 , A61M2005/2407 , A61M2005/2414 , A61M2005/247 , A61M2005/3267 , A61M2005/3289
摘要： An injection device which includes a housing (12), a needle hub (38) slidable within the housing (12), a needle (40) having a distal end piercing tip (42) and a proximal end piercing tip (44), the needle hub (40) being moveable from a first position wherein the distal piercing tip (42) is within the housing to a second position wherein the distal end piercing tip (42) extends outwardly of housing (12), a first spring (23) biasing the needle hub (38) towards the first position, and a cartridge receiving member (48) mounted within the housing, and a plunger rod assembly (166), the plunger rod assembly (166) having a distal interior chamber (102) and a proximal interior chamber (103), the distal interior chamber (102) being designed to receive a cartridge (85) containing a liquid (89), the cartridge having a septum (87) and a plunger (88) to prevent exit of the liquid, and a second needle hub (91) located in the proximal chamber, a second hollow needle (92) mounted in the second needle hub, the second hollow needle having a distal piercing tip (94) and a proximal piercing tip (93), the second hollow needle being moveable from a first non piercing position to a second position whereby said distal piercing tip (94) will pierce the septum (87).
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公开(公告)号：US20170056583A1
公开(公告)日：2017-03-02
申请号：US15120268
申请日：2015-02-23
CPC分类号： A61M5/158 , A61B17/205 , A61B17/3478 , A61B2017/00247 , A61K9/0019 , A61K35/12 , A61M5/1452 , A61M5/162 , A61M5/3298 , A61M2005/1581 , A61M2005/341
摘要： This document provides systems and methods that can be used for the practice of regenerative medicine. For example, this document provides devices and methods for injecting stem cell material into tissue, such as heart tissue.
摘要翻译： 本文件提供可用于再生医学实践的系统和方法。 例如，本文件提供了用于将干细胞材料注射到诸如心脏组织的组织中的装置和方法。
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公开(公告)号：US20170035962A1
公开(公告)日：2017-02-09
申请号：US15294845
申请日：2016-10-17
CPC分类号： A61M5/14244 , A61M5/003 , A61M5/1408 , A61M5/1413 , A61M5/14216 , A61M5/162 , A61M5/3297 , A61M5/3298 , A61M2005/14268 , A61M2005/1587
摘要： An infusion cartridge for use with an ambulatory infusion system can be provided with a preattached infusion set to eliminate potential leakage, potential snagging and other inconveniences from tubing connectors. The infusion cartridge can include a rigid housing, a collapsible fluid reservoir within the housing and a dispense mechanism for drawing fluid from the reservoir and sending it out an outlet port. A length of tubing can be fixedly attached to the outlet port in fluid communication with the outlet port. The length of tubing can extend as a unitary construct from the outlet port to a connector that connects to a cannula for delivering fluid from the reservoir to a user.
摘要翻译： 用于与步进输液系统一起使用的输液盒可以设置有预先连接的输液器，以消除管道连接器的潜在泄漏，潜在的阻塞和其它不便。 输液盒可以包括刚性壳体，壳体内的可折叠流体储存器和用于从储存器抽出流体并将其发送到出口的分配机构。 一段管道可以固定地连接到出口端口，与出口端口流体连通。 管道的长度可以作为整体结构从出口延伸到连接到插管的连接器，以将流体从储存器输送到使用者。
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