公开(公告)号：US20240325652A1

公开(公告)日：2024-10-03

申请号：US18709855

申请日：2022-11-09

申请人： SHL Medical AG

发明人： Christopher Foster ,  Ming-Ting Yin

IPC分类号： A61M5/315 ,  A61M5/20

CPC分类号： A61M5/31501 ,  A61M2005/202 ,  A61M2005/2026

摘要： The present disclosure provides an inner tubular body for a medicament delivery device. The inner tubular body extends along a longitudinal axis from a proximal end to a distal end. The inner tubular body includes a distal part and a proximal part. The distal part includes a flexible arm extending distally, the flexible arm comprises a first spring support at the distal end of the flexible arm and a plunger rod support at the distal end of the flexible arm. The first spring support is inclined in a radially inward direction and is configured to support a distal end of a drive spring of the medicament delivery device when the medicament delivery device is in a non-activated state. The distal part further includes a second spring support extending distally and being configured to support the distal end of the drive spring of the medicament delivery device when the medicament delivery device is in an activated state. The plunger rod support is configured to engage with a plunger rod of the medicament delivery device in order to inhibit a proximal movement of the plunger rod when the medicament delivery device is in the non-activated state. The first spring support is configured to interact with an activation button that is at a distal end of the medicament delivery device. Triggering of the activation button allows a radial outward deflection of the flexible arm thereby disengaging the plunger rod support from the plunger rod and disengaging the first spring support from the distal end of the drive spring.

公开(公告)号：US12102797B2

公开(公告)日：2024-10-01

申请号：US17329775

申请日：2021-05-25

申请人： E3D A.C.A.L LTD

发明人： Dmitri Sarkorov ,  David Daily ,  Lior Raday

IPC分类号： A61M5/20 ,  A61M5/24 ,  A61M5/315 ,  A61M5/32 ,  A61M5/46

CPC分类号： A61M5/20 ,  A61M5/2033 ,  A61M5/24 ,  A61M5/31513 ,  A61M5/3202 ,  A61M5/3275 ,  A61M5/46 ,  A61M2005/202 ,  A61M2005/208 ,  A61M2005/2086 ,  A61M2005/2407 ,  A61M2005/2411 ,  A61M2005/2492 ,  A61M2205/42

摘要： An automatic injection device including a generally cylindrical syringe body having an opening, an outlet and an inner cylindrical surface adapted to contain an injectable liquid to be injected at an injection site via the outlet; a piston disposed in the cylindrical syringe body; a driving assembly, including an elongate plunger element having a forward end adapted to be axially inserted into the generally cylindrical syringe body and an at least partial forward sealing element mounted onto the elongate plunger element adjacent the forward end for creating an at least temporary slidable seal between the elongate plunger element and the inner cylindrical surface, whereby axial insertion of the elongate plunger element and the forward sealing element into the generally cylindrical syringe body creates friction between the forward sealing element and the inner cylindrical surface and also creates an at least temporary air spring between the forward sealing element and the piston, wherein the friction and the air spring dampen motion of the elongate plunger element.

公开(公告)号：US12070586B2

公开(公告)日：2024-08-27

申请号：US17698568

申请日：2022-03-18

申请人： Novo Nordisk A/S

发明人： Tom Hede Markussen

IPC分类号： A61M5/20 ,  A61M5/315 ,  A61M5/24 ,  A61M5/31

CPC分类号： A61M5/31551 ,  A61M5/20 ,  A61M5/31525 ,  A61M5/31528 ,  A61M5/31553 ,  A61M5/3156 ,  A61M5/31585 ,  A61M2005/202 ,  A61M5/24 ,  A61M2005/3126 ,  A61M5/31583 ,  A61M5/31593

摘要： The present invention relates to a handheld mechanical injection device by which set doses of a liquid medicament can be injected from a medical reservoir. The medicament is expelled through an injection needle by release of a power reservoir in the device, the power reservoir being fully or partially released by actuation of a user operable release member being positioned at or near an upper end of the injection device, the upper end being that end of the injection device which is opposite the injection needle.

公开(公告)号：US20240252764A1

公开(公告)日：2024-08-01

申请号：US18441221

申请日：2024-02-14

申请人： Ypsomed AG

发明人： Philippe Kohlbrenner ,  Daniel Kuenzli ,  Christoph Meier ,  Peter Stettler ,  Juergen Wittmann ,  Martin Wittwer

IPC分类号： A61M5/315 ,  A61M5/20 ,  A61M5/24 ,  A61M5/31 ,  A61M5/32 ,  F04B49/10

CPC分类号： A61M5/31583 ,  A61M5/31533 ,  A61M5/31553 ,  A61M5/31555 ,  A61M5/31585 ,  A61M5/3204 ,  A61M5/3245 ,  F04B49/106 ,  A61M5/20 ,  A61M2005/202 ,  A61M5/24 ,  A61M2005/3125 ,  A61M2005/3126 ,  A61M2005/3142 ,  A61M5/31535 ,  A61M5/31536 ,  A61M5/31543 ,  A61M5/31558 ,  A61M5/31561 ,  A61M5/31575 ,  A61M5/31593 ,  A61M2005/3247 ,  A61M5/3257 ,  A61M5/326

摘要： A device for administering a fluid product includes a first housing part with a receiver for the product, a second housing part detachably connectable to the first housing part, a piston rod held such that it can be displaced for the exertion of an emptying movement, an actuatable or releasable drive element for the piston rod, a coupling element including a coupling input element that couples the drive element to the piston rod in a coupling engagement, transmits a driving force of the drive element to the piston rod, and triggers the emptying movement, and a decoupling element displaceably connected to the second housing part and coupled to the first housing part such that it is displaced, by a movement of the housing parts in relation to each other when the housing parts are separated into a decoupling position wherein the piston rod is decoupled from the coupling input element.

公开(公告)号：US11957886B2

公开(公告)日：2024-04-16

申请号：US17959194

申请日：2022-10-03

申请人： 410 Medical, Inc.

发明人： Mark D. Piehl ,  Galen C. Robertson ,  John Tyler Willis Hagler ,  Robert W. Titkemeyer ,  Frederic C. Feiler, Jr.

IPC分类号： A61M5/142 ,  A61M5/00 ,  A61M5/14 ,  A61M5/145 ,  A61M5/178 ,  A61M5/19 ,  A61M5/20 ,  A61M5/31 ,  A61M5/315 ,  A61M5/48 ,  A61M39/10 ,  A61M39/24 ,  A61M39/28

CPC分类号： A61M5/31581 ,  A61M5/002 ,  A61M5/007 ,  A61M5/1413 ,  A61M5/14244 ,  A61M5/1456 ,  A61M5/1782 ,  A61M5/19 ,  A61M5/2033 ,  A61M5/3146 ,  A61M5/3158 ,  A61M5/31586 ,  A61M5/486 ,  A61M5/488 ,  A61M39/10 ,  A61M39/105 ,  A61M39/24 ,  A61M39/28 ,  A61M2005/202 ,  A61M2005/2026 ,  A61M2005/2073 ,  A61M2005/3128 ,  A61M2005/31588 ,  A61M2039/2493 ,  A61M2205/332 ,  A61M2205/3331 ,  A61M2205/3379 ,  A61M2205/3584 ,  A61M2205/50

摘要： A system includes a tubing set and a drive assembly. The tubing set includes inlet tubing couplable to a source of fluid, a valve coupled to the inlet tubing, a syringe coupled to the inlet tubing via the valve, and outlet tubing coupled to the valve. The valve is configured to allow fluid to be drawn from the source of fluid via the inlet tubing into a syringe body of the syringe and to be expelled from the syringe body and through the outlet tubing, and to prevent fluid from being drawn from the outlet tubing into the syringe body and to prevent fluid expelled from the syringe body from flowing through the inlet tubing. The drive assembly is configured to reversibly receive the tubing set such that a drive mechanism is engaged with a plunger of the syringe to reciprocally translate the plunger relative to the syringe body.

公开(公告)号：US11883637B2

公开(公告)日：2024-01-30

申请号：US17064298

申请日：2020-10-06

申请人： Ypsomed AG

发明人： Patrick Hostettler ,  Markus Tschirren

IPC分类号： A61M5/31 ,  A61M5/315 ,  A61M5/20 ,  A61M5/32 ,  A61M5/145 ,  A61M5/46 ,  A61M5/48

CPC分类号： A61M5/31581 ,  A61M5/1454 ,  A61M5/20 ,  A61M5/2033 ,  A61M5/3157 ,  A61M5/3159 ,  A61M5/31583 ,  A61M5/31585 ,  A61M5/31586 ,  A61M5/3204 ,  A61M5/326 ,  A61M5/46 ,  A61M5/484 ,  A61M2005/202 ,  A61M2005/2013 ,  A61M2005/2086 ,  A61M2005/3143 ,  A61M2005/3152 ,  A61M2005/3247 ,  A61M2005/3267 ,  A61M2205/3341 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2207/00

摘要： An autoinjector for dispensing a liquid product, in particular a highly viscous medication, includes: a housing, a product container, which is arranged in the housing and has a slidable piston, wherein the piston can be slid in a dispensing direction in order to dispense the product contained in the product container, a forward drive element, which acts on the piston as the product is being dispensed, a first spring, which is preloaded such that the product can be dispensed from the product container by the sliding of the forward drive element and the piston, and a rotation element, which is operatively coupled to the forward drive element, wherein the first spring acts on the rotation element in such a way that the rotation element is set into rotation in order to dispense the product, wherein the rotation element or the forward drive element has a thread having a variable pitch.

公开(公告)号：US11738148B2

公开(公告)日：2023-08-29

申请号：US16759742

申请日：2018-10-29

申请人： Press-Q

发明人： Ziv Goldin ,  Amihay Avital ,  Alexander Kurayev

IPC分类号： A61M5/20 ,  A61M5/32

CPC分类号： A61M5/2033 ,  A61M5/3202 ,  A61M2005/202

摘要： Some embodiments of a low profile intramuscular auto-injector optionally comprise a contact surface contoured to fit a body surface. Optionally a height of the injector is less than ¼ a perimeter of the contact surface. Optionally a cover protects said contact surface. Optionally the device includes a priming mechanism coupled to the cover wherein removal of the cover activates the priming mechanism for priming the injector and/or increasing a height of the injector. Optionally the injector includes a cylindrical pharmaceutical reservoir rigidly attached to an injection needle. Optionally in a compact storage state the injection needle is at a low angle to the contact surface. Optionally during priming the needle and/or reservoir rotate to orient the needle at a higher angle to the contact surface.

公开(公告)号：US11723840B2

公开(公告)日：2023-08-15

申请号：US16664244

申请日：2019-10-25

申请人： Inovio Pharmaceuticals, Inc.

发明人： Daniel E. Williamson ,  John R. Marshall

IPC分类号： A61J1/20 ,  A61M5/30 ,  A61M5/178 ,  A61M5/20

CPC分类号： A61J1/2096 ,  A61M5/30 ,  A61J1/201 ,  A61M5/1782 ,  A61M5/2033 ,  A61M2005/202

摘要： Embodiments herein relate to the field of injections, for instance needle-free injections, and more specifically, to methods and apparatus for spring-driven intramuscular and intradermal injections. Provided in some embodiments are needle-free injectors adapted to deliver intradermal injections, as well as vial adaptors that are adapted to function as spacers when used with a needle-free injection device.

公开(公告)号：US20190247586A1

公开(公告)日：2019-08-15

申请号：US16389627

申请日：2019-04-19

申请人： Antares Pharma, Inc.

发明人： Benjamin Newton ,  Patrick Madsen ,  Matthew Rust ,  Janice Cox

IPC分类号： A61M5/315

CPC分类号： A61M5/31543 ,  A61M5/31536 ,  A61M5/31551 ,  A61M5/31585 ,  A61M2005/202 ,  A61M2005/2407 ,  G01F11/023 ,  G01F11/025 ,  G01F11/027

摘要： A dispensing mechanism for delivering a dosage of medicament including a housing having a proximal-distal axis; a plunger rod having a screw thread and configured to advance along the proximal-distal axis relative to the housing; a user-operable push button moveable along the proximal-distal axis relative to the housing; a twist driver threadably engaged with the push button such that movement of the push button towards the distal end of the housing causes rotation of the twist driver about the proximal-distal axis; and a driver engaged with the twist driver such that rotation of the twist driver causes rotation of the driver, the driver also engaged with a portion of the plunger rod such that rotation of the driver causes rotation of the plunger rod, advancing the plunger rod along the proximal-distal axis relative to the housing.

公开(公告)号：US20180099095A1

公开(公告)日：2018-04-12

申请号：US15832383

申请日：2017-12-05

申请人： WINDGAP MEDICAL, INC.

发明人： Adam R. Standley ,  Christopher J. Stepanian ,  Cole Constantineau ,  Michel Bruehwiler ,  Brent Buchine ,  Jeffrey Thomas Chagnon ,  Robert Brik

IPC分类号： A61M5/20 ,  A61M5/32 ,  A61M5/19 ,  A61M5/28 ,  A61M5/00 ,  A61M5/315 ,  A61M5/24 ,  A61M5/31

CPC分类号： A61M5/19 ,  A61M5/00 ,  A61M5/2033 ,  A61M5/2046 ,  A61M5/2053 ,  A61M5/2066 ,  A61M5/288 ,  A61M5/31596 ,  A61M5/32 ,  A61M5/3202 ,  A61M5/3204 ,  A61M5/321 ,  A61M5/3232 ,  A61M5/3234 ,  A61M5/3243 ,  A61M5/3245 ,  A61M5/326 ,  A61M5/3271 ,  A61M5/3293 ,  A61M39/22 ,  A61M2005/2006 ,  A61M2005/2013 ,  A61M2005/202 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/2474 ,  A61M2005/3118 ,  A61M2005/3128 ,  A61M2005/3132 ,  A61M2005/3247 ,  A61M2005/3267 ,  A61M2206/14

摘要： A portable auto-injector configured to store a dry medication separately from a liquid component, wherein removal of a cap operates a first actuation mechanism which opens a sliding valve and thus allows for the initiation of a mixing step prior to injection. An extendable needle guard is provided over the delivery assembly which prevents premature injection as well as inadvertent sticks or other cross contamination of a needle. The needle guard can also form part of a secondary trigger mechanism which injects the mixed components after the mixing stage is complete.