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    REAGENT-CATALYST DRIVEN SINGLE USE HYDRAULIC DRIVE AND SINGLE USE LARGE VOLUME INJECTOR
    1.
    发明公开
    REAGENT-CATALYST DRIVEN SINGLE USE HYDRAULIC DRIVE AND SINGLE USE LARGE VOLUME INJECTOR 审中-公开

    公开(公告)号：US20240009401A1

    公开(公告)日：2024-01-11

    申请号：US18473379

    申请日：2023-09-25

    申请人： Nypro Inc.

    发明人： Joshua Coyne

    IPC分类号： A61M5/315

    CPC分类号： A61M5/3153 ,  A61M5/3159 ,  A61M5/31501 ,  A61M2205/273

    摘要： Single use hydraulic drive devices and single use large volume injectors are described. A method for single use hydraulic drive including releasing a holding device to move a catalyst coated portion of a rod into a reagent filled chamber, generating pressure in the chamber due to at least one of gas creation and thermal expansion from a chemical reaction between the catalyst coated portion and the reagent, hydraulically displacing a moveable object in hydraulic communication with the chamber, and stopping further chemical reaction when the pressure exceeds a holding device force threshold to enable the holding device to re-hold a retracted catalyst coated portion of the rod outside of the chamber. The self-regulating pressure in the chamber enables a controlled rate of hydraulic displacement of the moveable object.

    Syringe Assembly with Plunger Rod Backstop and Method of Use
    7.
    发明申请
    Syringe Assembly with Plunger Rod Backstop and Method of Use 审中-公开
    带柱塞棒的注射器组件及其使用方法

    公开(公告)号：US20160144122A1

    公开(公告)日：2016-05-26

    申请号：US14555039

    申请日：2014-11-26

    申请人： Fisher Clinical Services GmbH

    发明人： Patrick Locati ,  Guido Hunkeler

    IPC分类号： A61M5/315

    CPC分类号： A61M5/31501 ,  A61M5/31505 ,  A61M5/3159 ,  A61M2005/3139 ,  A61M2005/31508 ,  A61M2202/0007 ,  A61M2207/00

    摘要： A syringe assembly includes a syringe barrel having a tubular body that bounds a compartment extending between a proximal end and an opposing distal end and a flange that radially outwardly projects from the proximal end of the body. A stopper is movably disposed with the compartment of the syringe barrel. A plunger rod includes a shaft having a proximal end and an opposing distal end and a plurality of teeth disposed on the shaft, the distal end of the shaft being secured to the stopper. A backstop engages the flange of the syringe barrel and at least a portion of the plurality of teeth of the plunger rod.

    摘要翻译： 注射器组件包括注射器筒体，该注射器筒体具有限定在近端和相对的远端之间延伸的隔间的管状体，以及从主体的近端径向向外突出的凸缘。 塞子与注射器筒的隔室可移动地设置。 柱塞杆包括具有近端和相对的远端的轴，以及设置在轴上的多个齿，轴的远端固定到止动件。 止回器接合注射器筒的凸缘和柱塞杆的多个齿的至少一部分。

    Injection Device
    8.
    发明申请
    Injection Device 有权
    注射装置

    公开(公告)号：US20160058950A1

    公开(公告)日：2016-03-03

    申请号：US14783484

    申请日：2014-04-08

    申请人： SANOFI

    发明人： William Marsh ,  Anthony Paul Morris ,  Joseph Butler ,  Matthew Jones

    IPC分类号： A61M5/315

    CPC分类号： A61M5/3159 ,  A61M5/20 ,  A61M5/31528 ,  A61M5/31541 ,  A61M5/31553 ,  A61M5/3157 ,  A61M5/31583 ,  A61M5/31586 ,  A61M5/31593 ,  A61M2005/3126 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583

    摘要： The invention refers to a handheld injection device comprising a housing (10; 410) and a dose indicator (90; 480) positioned within and axially constrained to the housing (10; 410) and rotatable with respect to the housing (10; 410) during dose setting and during dose dispensing. The dose indicator (90; 480) may comprise a flexible clicker arm (95; 482) which, only during dispense, is displaced in a first radial direction and, when the device reaches its minimum dose (zero) position, in a second, opposite radial direction.

    摘要翻译： 本发明涉及一种手持式注射装置，其包括定位在壳体（10; 410）内且轴向限制于壳体（10; 410）并可相对于壳体（10; 410）旋转的壳体（10; 410）和剂量指示器（90; 480） 在剂量设定期间和剂量分配期间。 剂量指示器（90; 480）可以包括柔性拨号臂（95; 482），其仅在分配期间在第一径向方向上移位，并且当装置达到其最小剂量（零）位置时， 径向相反。

    INJECTION DEVICES USING A RESILIENTLY COMPRESSIBLE TORSION SPRING AS DRIVING FORCE
    9.
    发明申请
    INJECTION DEVICES USING A RESILIENTLY COMPRESSIBLE TORSION SPRING AS DRIVING FORCE 有权
    使用可驱动的扭力弹簧作为驱动力的注射装置

    公开(公告)号：US20150100029A1

    公开(公告)日：2015-04-09

    申请号：US14400186

    申请日：2013-04-30

    申请人： Toby Cowe ,  Simon Reitter

    发明人： Toby Cowe ,  Simon Reitter

    IPC分类号： A61M5/315

    CPC分类号： A61M5/3159 ,  A61M5/20 ,  A61M5/31583 ,  Y10T29/49863

    摘要： An injection device includes a housing for receiving a syringe or cartridge for containing a medicament; a rotary driveshaft mounted for rotation relative to the housing; and an elongate coiled torsion spring having respective formations at opposite ends thereof, with a first formation being anchored in a seat on the rotary drive shaft and a second formation being anchored in a seat on a reaction component. In use relative rotation of the rotary driveshaft and the reaction component in one angular direction strains the torsion drive spring, and release of the strained torsion drive spring causes expression of medicament from the syringe or cartridge. The torsion spring is longitudinally resiliently compressible between its end formations whereby during assembly of the injection device, the torsion spring may be longitudinally compressed and then rotated, thereby urging the end formations of the torsion drive spring into engagement with the respective seats.

    摘要翻译： 注射装置包括用于接收用于容纳药物的注射器或药筒的壳体; 安装成相对于壳体旋转的旋转驱动轴; 以及细长的盘绕的扭转弹簧，其相对的端部具有相应的结构，第一结构被锚定在旋转驱动轴上的座中，第二结构锚定在反作用部件的座中。 在使用中，旋转驱动轴和反作用部件在一个角度方向的相对旋转使扭转驱动弹簧变形，并且应变扭转驱动弹簧的释放引起药物从注射器或药筒的表达。 扭转弹簧在其端部结构之间纵向可弹性压缩，由此在注射装置的组装期间，扭转弹簧可以被纵向压缩然后旋转，从而推动扭转驱动弹簧的端部结构与相应的座部接合。

    Drug Delivery Device and Method for Detection of End-Of-Dose Condition
    10.
    发明申请
    Drug Delivery Device and Method for Detection of End-Of-Dose Condition 审中-公开
    药物输送装置和用于检测剂量结束条件的方法

    公开(公告)号：US20150088092A1

    公开(公告)日：2015-03-26

    申请号：US14395976

    申请日：2013-04-24

    申请人： Novo Nordisk A/S

    发明人： Per Einar Pontus Holm ,  Jens A. Munk

    IPC分类号： A61M5/50

    CPC分类号： A61M5/5086 ,  A61M5/16831 ,  A61M5/31535 ,  A61M5/3159 ,  A61M2205/18 ,  A61M2205/3306

    摘要： Method for detecting an end-of-dose condition in a pressurized system, comprising the steps of (a) providing a system having a fluid-filled variable volume reservoir comprising an elastically deformable portion and an outlet, pressurizing means, and means for detecting a property of the elastically deformable portion which varies with the internal pressure in the reservoir, (b) pressurizing the reservoir to expel a desired amount of fluid by applying a force, thereby deforming the elastically deformable portion, (c) measuring, after the actuating step, a property related to the elastically deformable portion as it regains its initial configuration, (d) comparing a value for the measured property with one or more threshold values, and (e) providing a user with an indication when a given threshold value has been reached, and/or when a given threshold value has not been reached within a given period of time.

    摘要翻译： 一种用于检测加压系统中的剂量结束状况的方法，包括以下步骤：（a）提供具有流体填充的可变体积贮存器的系统，其包括可弹性变形的部分和出口，加压装置，以及用于检测 弹性变形部分的特性随储存器内部压力而变化，（b）通过施加力来加压贮存器以排出所需量的流体，从而使可弹性变形部分变形，（c）在致动步骤之后测量 （d）将所测量的属性的值与一个或多个阈值进行比较，以及（e）当给定的阈值已经被提供给用户时，向用户提供指示 和/或当给定的时间段内没有达到给定的阈值时。