公开(公告)号：US12023468B2

公开(公告)日：2024-07-02

申请号：US16980253

申请日：2019-03-12

申请人： MYLAN UK HEALTHCARE LTD. ,  COALESCE PRODUCT DEVELOPMENT LIMITED

发明人： Michael John Holroyd ,  Robin Craig Cocker ,  James Terrence Collins ,  Paul Christopher Edward Mutti ,  Daniel Colin Jackson ,  Michael Edgar Newton

IPC分类号： A61M5/20 ,  A61M5/315 ,  A61M5/32 ,  A61M5/24

CPC分类号： A61M5/20 ,  A61M5/2033 ,  A61M5/31591 ,  A61M5/3202 ,  A61M5/3204 ,  A61M5/326 ,  A61M2005/2013 ,  A61M2005/2403 ,  A61M2005/2488 ,  A61M2005/3267

摘要： A device for injecting a medicament is provided. The device has a housing with a container within it which can hold a medicament. At its proximal end the container has a needle and a stopper. The device includes a plunger which at one end can engage the stopper. At the opposite end, the plunger can engage a first resilient member to move the stopper within the container to inject the medicament from the container. The device includes a collar with distal and proximal ends, the distal end engaging with a carriage and causing its rotation and the proximal end engaging with a second resilient member. The second resilient member can engage with a skin sensor which has distal and proximal ends. At the proximal end, the skin sensor can contact an injection site. The housing has a cap which can reduce or prevent movement of the skin sensor.

公开(公告)号：US11980742B2

公开(公告)日：2024-05-14

申请号：US15533567

申请日：2015-12-22

申请人： Novo Nordisk A/S

发明人： Carsten Schau Andersen ,  Simon Roervig ,  Steffen Hansen

IPC分类号： A61M5/20 ,  A61M5/24 ,  A61M5/315 ,  A61M5/32 ,  A61M5/31 ,  A61M5/46

CPC分类号： A61M5/2033 ,  A61M5/2459 ,  A61M5/31536 ,  A61M5/31591 ,  A61M5/3202 ,  A61M5/3204 ,  A61M5/3232 ,  A61M5/3243 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/3109 ,  A61M2005/3154 ,  A61M2005/3254 ,  A61M2005/3267 ,  A61M5/46

摘要： A device for administering a fluid medicament by injection comprises a dosing portion (1) with a collapsible reservoir (10). The reservoir (10) has a maximum volume in an extended state and a minimum volume in a collapsed state. Prior to injection, the reservoir (10) is in the extended state and contains a liquid to be administered, and the reservoir (10) is biased towards the collapsed state. The device further comprises a needle (2), wherein a lumen (20) of the needle (2) is in fluid communication with the reservoir (10). The device further comprises a shield portion (3) with a plug (30). Prior to injection, the shield portion (3) is in a deployed position where the plug (30) blocks the lumen (20) of the needle (2). The shield portion (3) is adapted to move in response to an actuation force from the deployed position to a retracted position where the lumen (20) of the needle (2) is open, thereby causing the reservoir (10) to shift to the collapsed state to expel the liquid through the needle.

公开(公告)号：US20240042138A1

公开(公告)日：2024-02-08

申请号：US18492144

申请日：2023-10-23

申请人： Nancy C. Stamps

发明人： Nancy C. Stamps

IPC分类号： A61M5/315 ,  A61M5/00

CPC分类号： A61M5/31591 ,  A61M5/002 ,  A61K31/137

摘要： The present invention relates to a syringe and medical kit, which allow for doses of epinephrine of 0.15 mg or 0.15 mL, 0.3 mg or 0.3 mL, and 0.5 mg or 0.5 mL, the most commonly prescribed doses which are utilized today in treating anaphylaxis or other allergic reactions. Currently, existing syringes may include many markings of ten or more dosages. Although these prior art syringes are useful, it is difficult to use them for a patient who must quickly identify a correct dose level among many other marks. The above problem can be addressed by a syringe design which has only a few dosage markings, which correspond to commonly used standard dosages for children and adults. When used with a standard concentration of 1:1000 epinephrine solution, such a device can rapidly provide a known quantity of medicine to a patient who is in urgent need of it.

公开(公告)号：US10010483B2

公开(公告)日：2018-07-03

申请号：US15214432

申请日：2016-07-19

申请人： ANUTRA MEDICAL, INC.

发明人： Daniel K. Davidian ,  Scott G. Newnam ,  Eli B. Nichols ,  Theodore J. Mosler

IPC分类号： A61J1/20 ,  A61J1/22 ,  A61M5/315 ,  A61M5/178 ,  A61M5/00 ,  A61M5/31 ,  A61M5/24 ,  A61M5/50

CPC分类号： A61J1/2096 ,  A61J1/201 ,  A61J1/2055 ,  A61J1/2075 ,  A61J1/22 ,  A61M5/001 ,  A61M5/1782 ,  A61M5/2425 ,  A61M5/2448 ,  A61M5/3137 ,  A61M5/31586 ,  A61M5/31591 ,  A61M5/31593 ,  A61M5/502 ,  A61M2202/048 ,  A61M2205/75

摘要： A syringe fill system is described, which is useful for filling syringes for dental anesthetic applications. The system incorporates capability for “push-pull”, “pull-push”, “push-push”, and “pull-pull” modes of operation, for loading syringes with compositions comprising multiple fluid components. A syringe fillable by such syringe fill systems is described, providing haptic and audible feedback to a user, to aid in administering precise amounts of therapeutic compositions. Also disclosed are cassette assemblies for use in such syringe fill systems. Such cassette assemblies may be formed of plastic and elastomeric materials of construction, as disposable or single-use components of the syringe fill system.

公开(公告)号：US09931469B2

公开(公告)日：2018-04-03

申请号：US14462116

申请日：2014-08-18

申请人： Dr. Reddy's Laboratories, Ltd.

发明人： Adam M. Shain ,  Rajesh Kumar ,  Anil Namboodiripad

IPC分类号： A61M5/20 ,  A61M5/315 ,  A61M5/50 ,  A61M5/31 ,  A61M5/32

CPC分类号： A61M5/2033 ,  A61M5/3129 ,  A61M5/31546 ,  A61M5/31548 ,  A61M5/31553 ,  A61M5/31555 ,  A61M5/3156 ,  A61M5/31591 ,  A61M5/321 ,  A61M5/50 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/208 ,  A61M2005/3126 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583

摘要： An auto-injector device for administering a liquid pharmaceutical composition, in which an end-user can select between doses that the device is capable of delivering. The end-user choices that translate into the selected doses can be based on end-user perceived severity of symptoms, end-user weight and other such factors. In some embodiments the auto-injector is configured to administer the one chosen dose only. In other embodiments, the auto-injector can deliver second and subsequent doses up to full dose of the pharmaceutical composition disposed in the injector. The auto-injector can provide visual, audio, and tactile feedback, alone or in combination, to the user to indicate the dose selected, instructions for use, and when the dose has been administered.

公开(公告)号：US09802001B2

公开(公告)日：2017-10-31

申请号：US14782745

申请日：2014-04-08

申请人： SANOFI

发明人： Daniel David Higgins ,  Matthew Jones ,  Joseph Butler ,  William Marsh

IPC分类号： A61M5/315 ,  A61M5/20 ,  A61M5/24

CPC分类号： A61M5/31551 ,  A61M5/20 ,  A61M5/24 ,  A61M5/31525 ,  A61M5/31553 ,  A61M5/31558 ,  A61M5/31561 ,  A61M5/31583 ,  A61M5/31591 ,  A61M2005/2086

摘要： The present invention relates to a dispensing speed control mechanism for use in an injection device. The injection device may have a housing (10, 30, 40; 40′; 40″; 40′″) and a drive member (70), which is driven by a power reservoir (100, 100′) and axially movable between a dose setting position, in which the drive member (70) is rotationally constrained to the housing (10, 30, 40; 40′; 40″; 40′″), and a dose dispensing position, in which the drive member (70) is rotationally de-coupled from the housing (10, 30, 40; 40′; 40″; 40′″). The speed control mechanism comprises friction means (42) for retarding the drive member (70) during dose dispensing depending on the axial position of the drive member (70). Further, the invention relates to an injection device with such a dispensing speed control mechanism.

公开(公告)号：US20170290986A1

公开(公告)日：2017-10-12

申请号：US15480029

申请日：2017-04-05

申请人： University of Washington

发明人： Keith Chan ,  Ben Carney ,  Zachary Chen ,  Ha Seung Chung ,  Jazmine Saito ,  Wealth Mele Salvador ,  Shawn Swanson

IPC分类号： A61M5/24 ,  A61M5/315 ,  A61M5/32 ,  A61M5/28 ,  A61M5/31 ,  A61M5/20 ,  A61M5/19

CPC分类号： A61M5/2466 ,  A61M5/19 ,  A61M5/2033 ,  A61M5/288 ,  A61M5/3145 ,  A61M5/31591 ,  A61M5/3243 ,  A61M2005/2013 ,  A61M2005/2026 ,  A61M2005/208 ,  A61M2005/2407 ,  A61M2005/247 ,  A61M2005/3128 ,  A61M2205/581

摘要： An autoinjector is described that includes an outer body, a first trigger, an output needle, and a first compartment. The first compartment is positioned within the outer body and includes (i) a main body, (ii) a first biasing member coupled to the first trigger, and (iii) a protrusion positioned at a distal end of the main body. The autoinjector further includes a second compartment positioned in the outer body and in fluid communication with the first compartment and the output needle. The autoinjector also includes a second biasing member coupled to a second trigger. The first biasing member is configured to, upon application of force to the first trigger, automatically move an ampule in a distal direction relative to the main body to force the ampule against the protrusion, so as to break the ampule and allow a medicament to flow from the ampule to the second compartment.

公开(公告)号：US20170281871A1

公开(公告)日：2017-10-05

申请号：US15444598

申请日：2017-02-28

申请人： Joseph ONORATO

发明人： Joseph ONORATO

IPC分类号： A61M5/315 ,  A61M5/24 ,  A61M5/32 ,  A61M5/20 ,  A61M5/46

CPC分类号： A61M5/3156 ,  A61M5/20 ,  A61M5/2033 ,  A61M5/24 ,  A61M5/3153 ,  A61M5/3155 ,  A61M5/31553 ,  A61M5/31555 ,  A61M5/3158 ,  A61M5/31585 ,  A61M5/3159 ,  A61M5/31591 ,  A61M5/31593 ,  A61M5/3287 ,  A61M5/42 ,  A61M5/46 ,  A61M2210/04 ,  A61M2230/005

摘要： An auto-injector device including a syringe, a needle arranged in the vicinity of a first end of the syringe, and a plunger arranged within the syringe. A volume within the syringe between the plunger the needle accommodates medicine, such that movement of the plunger toward the needle dispenses medicine through the needle. A selection assembly configurable by a user to adjust an amount of medicine dispensed by the auto-injector device and depth to which the medicine is delivered. Also, a method for treating a skin lesion or skin disorder utilizing the auto-injector and a kit for patient administered treatment.

公开(公告)号：US20170274147A1

公开(公告)日：2017-09-28

申请号：US15177697

申请日：2016-06-09

申请人： Glenmark Pharmaceuticals S.A.

发明人： A.V.V.P.S. RAGHUVEER ,  Rajendra SHETTY ,  Prashant NAVALE

IPC分类号： A61M5/315

CPC分类号： A61M5/31548 ,  A23K40/00 ,  A61M5/3129 ,  A61M5/31505 ,  A61M5/31536 ,  A61M5/31553 ,  A61M5/31555 ,  A61M5/3156 ,  A61M5/31563 ,  A61M5/31565 ,  A61M5/31591 ,  A61M2005/3104 ,  A61M2005/311 ,  A61M2005/3125 ,  A61M2205/583 ,  A61M2250/00

摘要： Disclosed herein is a syringe device comprises (a) an outer housing, (b) a barrel, (c) a stopper, and (d) a plunger with one or more grooves.

公开(公告)号：US20170136190A1

公开(公告)日：2017-05-18

申请号：US15310208

申请日：2015-05-27

申请人： Sanofi-Aventis Deutschland GmbH

发明人： Matthew Meredith Jones ,  Samuel Keir Steel ,  Neal Alexander Blundred ,  Joseph Butler ,  Robert Frederick Veasey ,  David Plumptre ,  Anthony Paul Morris

IPC分类号： A61M5/315 ,  A61M5/32 ,  A61M5/24

CPC分类号： A61M5/31575 ,  A61M5/19 ,  A61M5/2448 ,  A61M5/31515 ,  A61M5/31528 ,  A61M5/31538 ,  A61M5/31551 ,  A61M5/31561 ,  A61M5/31585 ,  A61M5/31591 ,  A61M5/31593 ,  A61M5/31596 ,  A61M5/3295 ,  A61M2005/1787 ,  A61M2005/244 ,  A61M2005/3126

摘要： The invention is directed to a differential gear mechanism (26) for a drug delivery device with a primary drug delivery assembly (3) and a secondary drug delivery assembly (4), wherein the primary drug delivery assembly (3) comprises a primary dose dial sleeve (17) and wherein the secondary drug delivery assembly (4) comprises a secondary drive sleeve (24). The invention is also directed to a respective drug delivery device.