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公开(公告)号：US20240358923A1
公开(公告)日：2024-10-31
申请号：US18658491
申请日：2024-05-08
发明人： Elijah KAPAS , Matthew KANE , Conor CULLINANE
CPC分类号： A61M5/2033 , A61M5/14244 , A61M5/14248 , A61M5/20 , A61M5/46 , A61M2005/14284 , A61M2005/206 , A61M2005/2073 , A61M5/24 , A61M5/2466 , A61M2005/2474 , A61M5/31565 , A61M5/31571 , A61M5/3158 , A61M5/3202 , A61M5/3232
摘要： A novel single use auto-injector for delivering a fixed amount of medicament is described. The auto-injector may include a sealed housing rotatably held in a cover. Once the auto-injector is positioned at the injection location, the user can transition the housing from a locked to an armed position. The user can then compress the sealed housing into the cover, triggering activation mechanisms that initiate the injection. A first activation mechanism engages an interlock to prevent reuse of the auto-injector. A second activation mechanism straightens and extends a curved needle to a set the exposed needle length. A third activation mechanism pierces a sealed reservoir allowing the medicament to be forced through the injection needle. Following the injection, the auto-injector expands and interlocks, retracting the needle into the auto-injector and preventing reuse.
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公开(公告)号：US12102806B2
公开(公告)日：2024-10-01
申请号：US17658020
申请日：2022-04-05
申请人： SHL Medical AG
CPC分类号： A61M5/31556 , A61M5/31505 , A61M5/31541 , A61M5/3155 , A61M5/31565 , A61M5/3158 , A61M5/31581 , A61M5/31593 , A61M5/31585
摘要： An actuation mechanism is presented for a medicament delivery device having a plunger rod arranged to act on a stopper of a medicament container, an actuator arranged slidable and connected to the plunger rod for acting on the stopper when said actuator is operated by displacing it in a longitudinal direction of the actuation mechanism, and an activator for activating the actuation mechanism and for setting a dose. The activator having a generally tubular activator sleeve provided with a spirally extending groove on an outer surface, the groove arranged with a length corresponding to the total amount of medicament to be delivered in a number of doses contained in said medicament container, where the groove is provided with an end wall, a stop ring arranged coaxial with said activator sleeve. The activator sleeve arranged with a follower positioned in the groove and the follower arranged to abut the end wall when the total amount has been delivered.
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公开(公告)号：US20180185390A1
公开(公告)日：2018-07-05
申请号：US15579224
申请日：2016-06-02
发明人： Timothy J. Eviston , Arun Krishnan
IPC分类号： A61K31/573 , A61B5/0488 , A61K47/36
CPC分类号： A61K31/573 , A61B5/0488 , A61B17/3472 , A61B2090/3933 , A61B2090/3941 , A61B2505/05 , A61F9/0008 , A61K9/0024 , A61K47/36 , A61M5/14248 , A61M5/24 , A61M5/2422 , A61M5/2466 , A61M5/315 , A61M5/31565 , A61M5/31595 , A61M5/48 , A61M39/18 , A61M2005/005 , A61M2005/3117 , A61M2205/0266 , A61M2205/13 , A61M2205/586 , A61M2205/8206
摘要： Disclosed in some forms is a process of limiting the impact of surgery on a nerve, the process comprising applying a therapeutic substance to the nerve during surgery. In some aspects, disclosed is a formulation for reducing nerve trauma comprising an active pharmacological ingredient adapted to intervene in the activation of pathways of cellular degradation within the nerve and a carrier adapted to reduce dissemination of the active pharmacological ingredient beyond the site at which its effect is intended.
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公开(公告)号：US10004850B2
公开(公告)日：2018-06-26
申请号：US15078711
申请日：2016-03-23
申请人： Juvaplus SA
CPC分类号： A61M5/20 , A61M5/24 , A61M5/31565 , A61M5/31566 , A61M5/31571 , A61M5/31576 , A61M5/31586 , A61M2005/31588 , A61M2205/586
摘要： A syringe holder for a motorized injection device, the syringe holder being adapted to receive a receptacle intended to contain a fluid or viscous substance, preferably a disposable refillable receptacle or a syringe, as well as being adapted to be mounted on the motorized injection device such that the motorized injection device enables a part or all of the fluid or viscous substance contained in said receptacle to be expelled. The syringe holder includes a first activator portion to control a predefined function of the motorized injection device. The syringe holder is distinguished in that it comprises a second activator portion to control said predefined function of the motorized injection device independently from the first activator portion.
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公开(公告)号：US09987432B2
公开(公告)日：2018-06-05
申请号：US14861478
申请日：2015-09-22
发明人： Oz Cabiri , Ran Hezkiahu
CPC分类号： A61M5/31515 , A61M5/142 , A61M5/14248 , A61M5/1452 , A61M5/31501 , A61M5/31511 , A61M5/31565 , A61M5/31583 , A61M5/31586 , A61M2005/3123
摘要： A method and system are disclosed for driving a plunger in a drug reservoir. In some embodiments, a variable friction element interconnects between a pushing shaft and a wall of the reservoir. For example, rotation of a driving element in a first direction relative to the pushing shaft may advance the pushing shaft in the reservoir. The friction element may have increased friction resistance to rotation of the pushing shaft in the first direction in comparison to frictional resistance to advancing the pushing shaft. For example, the increased friction may result from wedging a radial element between the pushing shaft and the wall of the reservoir.
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公开(公告)号：US20170290988A1
公开(公告)日：2017-10-12
申请号：US15507861
申请日：2015-09-01
申请人： Novo Nordisk A/S
CPC分类号： A61M5/31565 , A61M5/14 , A61M5/20 , A61M5/24 , A61M5/31 , A61M5/3146 , A61M5/31515 , A61M5/31573 , A61M5/365 , A61M2005/31588 , A61M2205/33 , A61M2205/332
摘要： A drug delivery device (100) for estimating the amount of free air in a cartridge (1) comprising a cartridge receiving portion (not shown) adapted to receive a cartridge (1), the cartridge (1) comprising a body portion (6), an axially displaceable piston (5), and a distal outlet portion (4), an expelling assembly comprising an axially displaceable piston drive member (10) adapted to interface with the proximal piston (5) portion of a received cartridge (1), the piston drive member (10) is adapted to be moveable in a distal direction, and to thereby pressurize the drug in a received cartridge. The drug delivery device further comprises means for measuring and acquiring a property relating to a fluid pres-sure of the drug in a received cartridge (1), and where the property depends on the amount of free air (7) contained in the cartridge (1). The drug delivery device further comprises means (20) for measuring and acquiring the position of the piston rod drive member (10), and means (40) for measuring and acquiring the time. The drug delivery device further comprises means (30) for storing, and means (31) for processing the acquired measurements. The processing means are configured for estimating the amount of air (7) in the cartridge (1).
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公开(公告)号：US20170274147A1
公开(公告)日：2017-09-28
申请号：US15177697
申请日：2016-06-09
IPC分类号： A61M5/315
CPC分类号： A61M5/31548 , A23K40/00 , A61M5/3129 , A61M5/31505 , A61M5/31536 , A61M5/31553 , A61M5/31555 , A61M5/3156 , A61M5/31563 , A61M5/31565 , A61M5/31591 , A61M2005/3104 , A61M2005/311 , A61M2005/3125 , A61M2205/583 , A61M2250/00
摘要： Disclosed herein is a syringe device comprises (a) an outer housing, (b) a barrel, (c) a stopper, and (d) a plunger with one or more grooves.
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公开(公告)号：US09672328B2
公开(公告)日：2017-06-06
申请号：US14797044
申请日：2015-07-10
发明人： Sean Saint , Arnold Holmquist , Cory McCluskey , Jack Pryor , Jasper Benke
CPC分类号： G16H20/17 , A61M5/31525 , A61M5/31528 , A61M5/31545 , A61M5/31565 , A61M5/31566 , A61M5/31568 , A61M2005/14208 , A61M2005/3126 , A61M2205/3584 , A61M2205/52 , G06F19/00 , G06F19/3462 , G06F19/3468 , G16H20/13 , H04B7/24 , H04L9/08 , H04L9/30
摘要： Methods, systems, and devices are disclosed for administering a medicament to a patient. In one aspect, a system includes an injection pen device in wireless communication with a mobile communication device. The injection pen device includes a housing including a chamber to encase a cartridge containing medicine, a dose setting and dispensing mechanism to set the mechanism to dispense a particular dose of the medicine from the loaded cartridge, a sensor unit to detect a dispensed dose based on positions and/or movements of the dose setting and dispensing mechanism, and an electronics unit in communication with the sensor unit to process the detected dispensed dose and time data associated with a dispensing event and to wirelessly transmit the dose data to a user's device. The mobile communication device provides a software application to provide the user with health information using the processed dose data.
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公开(公告)号：US09610407B2
公开(公告)日：2017-04-04
申请号：US14793076
申请日：2015-07-07
CPC分类号： A61M5/20 , A61M5/14546 , A61M5/14566 , A61M5/31546 , A61M5/31565 , A61M2005/31588 , A61M2205/14 , A61M2205/3327
摘要： A medicament delivery device comprises a housing, a holder within the housing for receiving a medicament cartridge, a piston rod for driving a bung of the medicament cartridge, a drive mechanism including a motor for providing an output drive to the piston rod for delivering the medicament and control means for controlling operation of the device. The device is additionally provided with a bung sensor for sensing when the piston rod is in contact with the bung and the control means is operative for advancing the drive of the piston rod towards the bung.
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公开(公告)号：US09604009B2
公开(公告)日：2017-03-28
申请号：US14319394
申请日：2014-06-30
CPC分类号： A61M5/24 , A61M5/31528 , A61M5/31533 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31546 , A61M5/31551 , A61M5/3156 , A61M5/31563 , A61M5/31565 , A61M5/31568 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M5/32 , A61M2005/2407 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要： A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.
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