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公开(公告)号:US12053617B2
公开(公告)日:2024-08-06
申请号:US16601824
申请日:2019-10-15
申请人: AMGEN INC.
发明人: Matias Melander , Jakob Halkjaer Pedersen , Christian Plambech , Adam B. McCullough , Julian Jazayeri
CPC分类号: A61M5/24 , A61M5/3129 , A61M5/3148 , A61M5/2033 , A61M2005/208 , A61M2005/2086 , A61M2005/3143 , A61M5/31585 , A61M2005/3267
摘要: A drug delivery device includes a housing defining a shell having a proximal and a distal end, a needle assembly at least partially disposed within the housing at the proximal end, a drive assembly at least partially disposed within the housing, and a damper mechanism at least partially disposed within the housing adjacent to the distal end. The housing further defines a longitudinal axis extending between the proximal end and the distal end. The needle assembly includes a syringe barrel containing a medicament and a needle or a cannula. The drive assembly is operably coupled to the needle assembly to urge the medicament through the needle or cannula. The damper mechanism is operably coupled to the drive assembly and the housing. Upon activating the drive assembly, the damper mechanism dampens an effect thereof.
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公开(公告)号:US20240197994A1
公开(公告)日:2024-06-20
申请号:US18435702
申请日:2024-02-07
申请人: Sanofi
发明人: Beate Franke
CPC分类号: A61M5/2033 , A61M5/3202 , A61M2005/2013 , A61M2005/202 , A61M2005/206 , A61M2005/2073 , A61M2005/2086
摘要: An injector device includes an elongate housing configured to receive container of medicament. The injector device also includes a needle sleeve mounted within the housing and moveable between an extended position in which the needle sleeve at least partially extends from the distal end of the housing, and a retracted position in which the needle sleeve is received further within the housing than in the extended position. The injector device also includes a release mechanism configured to control actuation of a piston rod. The release mechanism includes a rotatable member disposed within the housing and in cooperating engagement with the needle sleeve such that movement of the needle sleeve from the extended position to the retracted position causes the rotatable member to rotate within the housing from a first position to a second position.
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公开(公告)号:US11786658B2
公开(公告)日:2023-10-17
申请号:US17082547
申请日:2020-10-28
申请人: E3D A.C.A.L LTD
发明人: Dmitri Sarkorov , Lior Raday , David Daily , Menachem Zucker
CPC分类号: A61M5/2033 , A61M5/3158 , A61M5/31581 , A61M5/3204 , A61M5/46 , A61M2005/202 , A61M2005/2073 , A61M2005/2086 , A61M2205/583
摘要: A user-powered medicament injector including a reusable, user-powered automatic injection assembly including a user energizable medicament injection subassembly and a medicament module removably insertable into the reusable, user-powered automatic injection assembly and including a module housing adapted to receive a syringe having a barrel, a needle engaged to said barrel, and a removable needle cap covering the needle; a needle shield configured to be moveable with respect to the module housing and a needle cap remover associated with the needle shield. The medicament module is configured for energizing the user energizable medicament injection subassembly by insertion of the medicament module into the reusable, user powered automatic injection assembly.
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公开(公告)号:US20190175837A1
公开(公告)日:2019-06-13
申请号:US16280488
申请日:2019-02-20
申请人: kaleo, Inc.
CPC分类号: A61M5/2033 , A61M5/20 , A61M5/2066 , A61M5/315 , A61M5/3202 , A61M5/3204 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2005/208 , A61M2005/2086
摘要: An apparatus includes a housing, a medicament container and a movable member. The medicament container is configured to move within the housing between a first position and a second position in response to a force produced by an energy storage member. A proximal end portion of the medicament container includes a flange and has a plunger disposed therein. A first shoulder of the movable member is configured to exert the force on the flange to move the medicament container from the first position to the second position. A portion of the first shoulder deforms when the medicament container is in the second position such that at least a portion of the force is exerted upon the plunger. A second shoulder of the movable member is configured to exert a retraction force on the flange to move the medicament container from the second position towards the first position.
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公开(公告)号:US20180344941A1
公开(公告)日:2018-12-06
申请号:US16059860
申请日:2018-08-09
发明人: Toby Cowe
CPC分类号: A61M5/31595 , A61M5/20 , A61M5/2033 , A61M5/3157 , A61M5/3204 , A61M5/46 , A61M2005/202 , A61M2005/206 , A61M2005/2073 , A61M2005/208 , A61M2005/2086 , A61M2005/3125 , A61M2005/3126 , A61M2205/581 , A61M2205/583 , A61M2205/586
摘要: An injector device includes an injector body that receives a syringe; and an injection assembly being configured to dispense medicament from the syringe in a dispensation step. Certain types of injector devices include a sudden completion indicator that indicates when the injection is completed. Certain types of injector devices are configured to dispense two different medicament formulations having different viscosities from syringes without making any changes to the injector devices other than to switch out the syringes. Certain types of injector devices include safety arrangements that inhibit firing of the injector device until front and rear housing assemblies are disposed in predetermined rotational and axial positions relative to each other.
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公开(公告)号:US20180147355A1
公开(公告)日:2018-05-31
申请号:US15580181
申请日:2016-06-30
CPC分类号: A61M5/2066 , A61M5/2448 , A61M5/2459 , A61M5/284 , A61M5/31596 , A61M2005/2086 , A61M2005/31598
摘要: The present disclosure relates to a syringe for mixing two substances which have been retained separately inside the syringe, for instance in a storage condition. In particular the present disclosure relates to a syringe for 1) retaining a dry composition in a vacuum, and 2) mixing the dry composition with an aqueous medium to form a flowable substance. One embodiment relates to a syringe for retaining and mixing first and second substances comprising: a barrel comprising a sealable and/or closable distal outlet and a vacuum chamber for holding a first substance, a plunger incorporating a reservoir chamber for holding a second substance and configured to be axially displaced through a proximal end of the barrel, a membrane separating the vacuum chamber and the reservoir chamber, and a pointed member, such as one or more needles, for penetrating the membrane.
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公开(公告)号:US09895492B2
公开(公告)日:2018-02-20
申请号:US13902387
申请日:2013-05-24
申请人: APTAR FRANCE SAS
发明人: David Fabien , Matthieu Walter , Antoine Mansencal
CPC分类号: A61M5/20 , A61M5/2033 , A61M5/3157 , A61M5/3204 , A61M5/326 , A61M5/3272 , A61M39/1055 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2005/2086 , A61M2005/3125 , A61M2205/3327 , A61M2205/3368 , A61M2205/581 , A61M2205/582 , A61M2205/584 , F04C2270/0421
摘要: An autoinjector having a lower body (10; 1010) receiving a reservoir, a piston, a needle, an actuating sleeve (11; 1011) with a contact end to contact the user. The actuating sleeve is displaceable between projected positions and an actuation position, being in a first projected position prior to actuation of the autoinjector. The autoinjector also having an injection device (5, 8; 1005, 1008) and an injection lock. The actuating sleeve is automatically returns to the second projected position when the user removes the autoinjector from his body and is locked in this second projected position. The autoinjector includes an external shell (22; 1022) having a display window for indicating the actuation sequences, at least one display window (221; 1221; 1023) indicating to the user that the injection of the fluid product is finished.
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公开(公告)号:US09827374B2
公开(公告)日:2017-11-28
申请号:US14048601
申请日:2013-10-08
发明人: Toby Cowe
CPC分类号: A61M5/31595 , A61M5/20 , A61M5/2033 , A61M5/3157 , A61M5/3204 , A61M5/46 , A61M2005/202 , A61M2005/206 , A61M2005/2073 , A61M2005/208 , A61M2005/2086 , A61M2005/3125 , A61M2005/3126 , A61M2205/581 , A61M2205/583 , A61M2205/586
摘要: An injector device includes an injector body that receives a syringe; and an injection assembly being configured to dispense medicament from the syringe in a dispensation step. Certain types of injector devices include a sudden completion indicator that indicates when the injection is completed. Certain types of injector devices are configured to dispense two different medicament formulations having different viscosities from syringes without making any changes to the injector devices other than to switch out the syringes. Certain types of injector devices include safety arrangements that inhibit firing of the injector device until front and rear housing assemblies are disposed in predetermined rotational and axial positions relative to each other.
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公开(公告)号:US20170165426A1
公开(公告)日:2017-06-15
申请号:US15323560
申请日:2015-07-02
申请人: APTAR FRANCE SAS
发明人: David FABIEN
CPC分类号: A61M5/2033 , A61M5/31515 , A61M5/3158 , A61M5/326 , A61M5/46 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2205/581
摘要: An autoinjector having a reservoir containing fluid and including: a piston; a piston rod cooperating with the piston and is movable between a rest position and an injection position in which the piston rod has moved the piston to inject the fluid; an actuator spring urging the piston rod towards its injection position; a force-adjustment system exerting at least one force on the piston rod, the force adding to the force exerted by the spring on the piston rod at the beginning of injection; two pivot members cooperating with the piston rod and are connected together by two resilient elements, at least one pivot member being blocked prior to actuation by a locking system, thus preventing the autoinjector from being actuated, and an unlocking element adapted to move and/or to deform the locking system so as to unblock the at least one pivot member.
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公开(公告)号:US09616174B2
公开(公告)日:2017-04-11
申请号:US13902403
申请日:2013-05-24
申请人: APTAR FRANCE SAS
发明人: David Fabien , Antoine Mansencal , Matthieu Walter
CPC分类号: A61M5/20 , A61M5/2033 , A61M5/3157 , A61M5/3204 , A61M5/326 , A61M5/3272 , A61M39/1055 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2005/2086 , A61M2005/3125 , A61M2205/3327 , A61M2205/3368 , A61M2205/581 , A61M2205/582 , A61M2205/584 , F04C2270/0421
摘要: An autoinjector having an external shell (1022), a reservoir, a piston, a needle, a piston rod (1005) that is displaceable between a loaded position and an injection position in which the piston rod has displaced the piston of the reservoir to inject the fluid product through the needle, an injection spring (1008) to stress the piston rod towards the injection position, and a mobile element (1004; 1006), the piston rod displaceable relative to the mobile element. The autoinjector also includes an indication device (1500) having a key (1120), and a head part (1122). The mobile element including a deformable tab (1510; 1520), the head part cooperating prior to injection with the deformable tab to prevent any radial deformation, blocking the mobile element relative to the external shell. The piston rod, on completion of injection, exerting traction on the head part causing displacement of the key and enabling radial deformation of the deformable tab and axial displacement of the mobile element.
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