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    Method for the preparation of blood samples for automated analysis
    4.
    发明授权
    Method for the preparation of blood samples for automated analysis 失效
    血液样品制备方法用于自动分析

    公开(公告)号：US4209548A

    公开(公告)日：1980-06-24

    申请号：US862735

    申请日：1977-12-21

    申请人： James W. Bacus

    发明人： James W. Bacus

    IPC分类号： G01N1/28 ,  G01N33/96 ,  B44D1/02

    CPC分类号： G01N33/96 ,  G01N1/2813 ,  G01N2496/05

    摘要： A method for preparing blood samples containing red blood cells for automated analysis wherein the blood sample on a slide is spun to create a monolayer of randomly distributed red blood cells. To inhibit cell morphology distortions from occurring during drying, the morphologies of the cells contained in the monolayer are preserved by a fixing agent after monolayer preparation but prior to drying when such distortions would otherwise develop. The method and apparatus are particularly useful for fixing red blood cells to prevent loss of or deformation of a central pallor which would be detrimental to a subsequent automated analysis.

    摘要翻译： 一种用于制备含有红细胞的血液样品用于自动分析的方法，其中将载玻片上的血液样品旋转以产生随机分布的红细胞的单层。 为了抑制干燥期间发生的细胞形态变形，单层制备后的固定剂保留单层中所含的细胞的形态，但在干燥之前，如果这种变形会另外发生，则保留细胞的形态。 该方法和装置对于固定红细胞特别有用，以防止对随后的自动化分析有害的中央苍白体的损失或变形。

    System and method for facilitating a performance review process
    6.
    发明申请
    System and method for facilitating a performance review process 审中-公开
    用于促进绩效审查过程的系统和方法

    公开(公告)号：US20040143489A1

    公开(公告)日：2004-07-22

    申请号：US10348194

    申请日：2003-01-20

    申请人： Rush-Presbyterian - St. Luke's Medical Center

    发明人： Andrew N. Garman

    IPC分类号： G06F017/60

    CPC分类号： G06Q10/10 ,  G06Q10/06398

    摘要： A method for facilitating a performance review process. The method comprises receiving a list of reviewers and their relationship to a reviewee, generating an evaluation form for each reviewer based on the relationship between the reviewer and the reviewee, providing each reviewer with access to the evaluation form for completion, processing the completed evaluation form, and providing an evaluation results report.

    摘要翻译： 一种促进绩效审查过程的方法。 该方法包括接收审核人员的列表及其与审核人员的关系，根据评审者与审核人员之间的关系，为每位评审者生成评估表单，为每位评审者提供访问评估表以完成，处理完成的评估表单 ，并提供评估结果报告。

    Method for preventing sexually transmitted diseases
    7.
    发明授权
    Method for preventing sexually transmitted diseases 有权
    防治性传播疾病的方法

    公开(公告)号：US6028115A

    公开(公告)日：2000-02-22

    申请号：US243035

    申请日：1999-02-03

    申请人： Lourens Jan Dirk Zaneveld ,  Robert Anthony Anderson, Jr. ,  Xiao Hui Diao ,  Paul Robert Young, Jr. ,  Donald Paul Waller ,  Sanjay Garg ,  Calvin J. Chany, II

    发明人： Lourens Jan Dirk Zaneveld ,  Robert Anthony Anderson, Jr. ,  Xiao Hui Diao ,  Paul Robert Young, Jr. ,  Donald Paul Waller ,  Sanjay Garg ,  Calvin J. Chany, II

    IPC分类号： A61K31/192 ,  A61K31/70 ,  A61K31/775 ,  A01N31/10 ,  A01N31/14 ,  A01N35/00 ,  A61K31/74 ,  A61K47/48

    CPC分类号： A61K31/192 ,  A61K31/70 ,  A61K31/775

    摘要： A method for the reduction in the risk of transmitting a sexually transmitted disease--especially HIV and/or HSV--during sexual activity is provided. This method generally comprises the application of an effective amount of an inhibitory agent, preferably as a topical formulation, to the area or areas of sexual contact prior to engaging in sexual activity. Inhibitory agents which are useful in the present invention include, for example, phosphorylated hesperidins, sulfonated hesperidins, polystyrene sulfonates, substituted benzenesulfonic acid formaldehyde co-polymers, H.sub.2 SO.sub.4 -modified mandelic acids, and the like. This method can be used by heterosexuals, homosexuals, and/or bisexuals engaged in a wide variety of sexual activities. In addition to anti-STD activity, these agents may also act as vaginal contraceptives; moreover, they generally have fewer side effects than conventional vaginal contraceptives (e.g., nonoxynol-9). For example, the compounds useful in this invention are generally not toxic to natural and beneficial vaginal flora and, thus, do not upset the local microbiological balance. The anti-STD method of the present invention has the added advantage that it can be implemented and controlled by either sexual party. Methods are also provided for reducing the risk of transmission of STD-causing organisms to health care providers and laboratory personnel (or other persons) who may come into contact with biological samples and specimens.

    摘要翻译： 提供了一种在性活动期间降低传播性传播疾病（特别是艾滋病毒和/或HSV）风险的方法。 该方法通常包括在进行性活动之前将有效量的抑制剂，优选作为局部制剂施用于性接触的区域或区域。 可用于本发明的抑制剂包括例如磷酸化的hesperidins，磺化的hesperidins，聚苯乙烯磺酸盐，取代的苯磺酸甲醛共聚物，H2SO4改性的扁桃酸等。 这种方法可以被从事各种性活动的异性恋者，同性恋者和/或双性恋者使用。 除了抗STD活动外，这些药物还可以作为阴道避孕药具; 此外，它们通常具有比常规阴道避孕药（例如壬苯醇酯-9）更少的副作用。 例如，本发明中有用的化合物通常对天然和有益的阴道菌群是无毒的，因此不会扰乱局部的微生物平衡。 本发明的抗STD方法具有附加的优点，可以由任何一方实施和控制。 还提供了减少导致STD的生物传播给可能与生物样品和标本接触的保健提供者和实验室人员（或其他人员）的风险的方法。

    Method and apparatus for placement of an embolic coil
    8.
    发明授权
    Method and apparatus for placement of an embolic coil 失效
    用于放置栓塞线圈的方法和装置

    公开(公告)号：US5108407A

    公开(公告)日：1992-04-28

    申请号：US535386

    申请日：1990-06-08

    申请人： Glen K. Geremia ,  Michael Haklin

    发明人： Glen K. Geremia ,  Michael Haklin

    IPC分类号： A61B17/12 ,  A61B18/28

    CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61B18/28 ,  A61B2017/12068 ,  A61B2017/12072 ,  Y10S623/90 ,  Y10S623/903

    摘要： Method and apparatus for placing therapeutic devices such as embolic coils includes a probe assembly carried within a catheter. The probe assembly includes a fiber-optic cable with a connector retained thereon by crimping. The connector has a cable-receiving end resembling a ferrule, which is crimped about the cable. The other end of the connector provides mounting of a therapeutic device, such as an embolic coil. Heat releasable adhesive bonds the therapeutic device to the mounting portion of the connector. Laser energy transmitted through the fiber-optic cable is converted to heat by the connector, which thereupon becomes heated, releasing the adhesive bond between the connector and the therapeutic device. The probe assembly can then be withdrawn from the treatment site.

    摘要翻译： 用于放置治疗装置如栓塞线圈的方法和装置包括在导管内承载的探针组件。 探针组件包括通过卷曲保持在其上的连接器的光纤电缆。 连接器具有类似于套圈的电缆接收端，其围绕电缆卷曲。 连接器的另一端提供诸如栓塞线圈之类的治疗装置的安装。 热释放性粘合剂将治疗装置粘合到连接器的安装部分。 通过光纤电缆传输的激光能量被连接器转换成热量，然后连接器被加热，释放连接器和治疗装置之间的粘合剂粘结。 然后可以从治疗部位取出探针组件。

    Inhibition of bone resorption
    9.
    发明授权
    Inhibition of bone resorption 失效
    抑制骨吸收

    公开(公告)号：US4176177A

    公开(公告)日：1979-11-27

    申请号：US961296

    申请日：1978-11-16

    申请人： Klaus E. Kuettner

    发明人： Klaus E. Kuettner

    IPC分类号： A61K35/24 ,  A61K35/32 ,  A61K35/34 ,  A61K35/44

    CPC分类号： A61K35/24 ,  A61K35/32 ,  A61K35/34 ,  A61K35/44

    摘要： A method for regulating bone resorption wherein the bone is exposed to an effective amount of a composition of matter obtained from avascular or poorly vascularized tissue by extracting the tissue with an aqueous extraction medium which includes a solute which does not irreversibly denature the proteinaceous matter to be extracted and recovering from the aqeuous extract substances having molecular weight below about 50,000.

    摘要翻译： 一种用于调节骨吸收的方法，其中通过用含水提取介质提取组织来暴露有效量的由无血管或血管不全组织获得的物质的组合物，所述水性提取介质包括不会使蛋白质物质变性的溶质 从分子量低于约50,000的酸性提取物提取和回收。

    Dual resolution method and apparatus for use in automated classification of pap smear and other samples
    10.
    发明授权
    Dual resolution method and apparatus for use in automated classification of pap smear and other samples 失效
    双分辨方法和装置，用于自动分类pap涂片和其他样品

    公开(公告)号：US4175860A

    公开(公告)日：1979-11-27

    申请号：US801623

    申请日：1977-05-31

    申请人： James W. Bacus

    发明人： James W. Bacus

    IPC分类号： A61B10/00 ,  G01N33/48 ,  G06K9/00 ,  G01N33/16

    CPC分类号： G06K9/00127

    摘要： A method and apparatus is disclosed for use in performing automated classification of cells of a pap smear as well as other types of cells, such as red blood cells and blood cell neutrophiles. The apparatus generates an image that is split into two paths, (1) a high resolution image of primarily the nucleus of a cell, and (2) a low resolution image of the total cell, nucleus and cytoplasm. An image scanning device located in the first path provides output signals representing the image and circuitry performs measurement and analysis relating to texture of the nucleus. The image in the other path is demagnified which provides an enlarged, lower resolution image of the entire cell, including the nucleus and the cytoplasm and it is projected to a second image scanning device, which provides electrical signals that represent the image of the larger area and circuitry performs measurement and analysis relating to the size, density and color of the cytoplasm and the nucleus. The analysis obtained from each of the two circuits are applied to classification logic circuitry for the purpose of determining malignant cells.

    摘要翻译： 公开了用于对pap涂片的细胞进行自动分类以及其它类型的细胞（例如红细胞和血细胞嗜中性细胞）的方法和装置。 该装置产生分成两条路径的图像，（1）主要是细胞核的高分辨率图像，和（2）总细胞，细胞核和细胞质的低分辨率图像。 位于第一路径中的图像扫描装置提供表示图像的输出信号，并且电路执行与核的纹理相关的测量和分析。 其他路径中的图像被缩小，其提供整个细胞的扩大的较低分辨率图像，包括细胞核和细胞质，并且其被投影到第二图像扫描装置，其提供表示较大面积的图像的电信号 并且电路执行与细胞质和细胞核的大小，密度和颜色有关的测量和分析。 从两个电路中的每一个获得的分析被应用于分类逻辑电路，以便确定恶性细胞。