知搜-全球专利检索

  1. 登录
  2. 注册

搜索结果

17 条记录 (耗时 0.018 秒)

    Reagent container and reagent set
    3.
    发明授权
    Reagent container and reagent set 有权
    试剂容器和试剂组

    公开(公告)号：US08679425B2

    公开(公告)日：2014-03-25

    申请号：US12837869

    申请日：2010-07-16

    申请人： Sachiko Ueda ,  Yusuke Mori ,  Hiroyuki Ohashi ,  Yuji Itose ,  Kinya Uchihashi ,  Yoichi Nakamura ,  Kohei Sugitani

    发明人： Sachiko Ueda ,  Yusuke Mori ,  Hiroyuki Ohashi ,  Yuji Itose ,  Kinya Uchihashi ,  Yoichi Nakamura ,  Kohei Sugitani

    IPC分类号： B01L3/00 ,  B01L9/00 ,  B01L99/00 ,  B65D21/02 ,  B65D1/24 ,  B65D25/04 ,  B65D57/00 ,  B65D85/00 ,  G01N21/00 ,  G01N31/00 ,  G01N33/00 ,  A47B77/00 ,  B65D6/28

    CPC分类号： B01L3/0293 ,  B01L3/527 ,  B01L9/00 ,  B01L2200/185 ,  B01L2300/021 ,  G01N35/1002

    摘要： A reagent container set is disclosed which comprises: a first reagent container for accommodating a first reagent to be used in a sample analyzer, the top part of the first reagent container having a first aspiration opening for inserting a first reagent aspirating tube to aspirate the first reagent; a waste fluid container for accommodating the first reagent used in the sample analyzer as a waste fluid, the top of the waste fluid container having a discharge opening for inserting a waste fluid discharging tube to discharge the waste fluid into the waste fluid container; a box for accommodating the first reagent container and the waste fluid container; and a container holding member for holding the first reagent container and the waste fluid container so that the first aspiration opening and the discharge opening are disposed at predetermined positions, the container holding member being maintained at a predetermined position within the box.

    摘要翻译： 公开了一种试剂容器组，其包括：第一试剂容器，用于容纳待用于样本分析仪的第一试剂，所述第一试剂容器的顶部具有用于插入第一试剂抽吸管的第一抽吸开口， 试剂; 用于将用于样品分析器中的第一试剂用作废液的废液容器，废液容器的顶部具有用于插入废液排放管的排出口，以将废液排放到废液容器中; 用于容纳第一试剂容器和废液容器的箱体; 以及容器保持构件，用于保持第一试剂容器和废液容器，使得第一抽吸开口和排出口设置在预定位置，容器保持构件保持在箱内的预定位置。

    REAGENT CONTAINER AND REAGENT SET
    4.
    发明申请
    REAGENT CONTAINER AND REAGENT SET 有权
    试剂容器和试剂组

    公开(公告)号：US20110014095A1

    公开(公告)日：2011-01-20

    申请号：US12837869

    申请日：2010-07-16

    申请人： Sachiko UEDA ,  Yusuke Mori ,  Hiroyuki Ohashi ,  Yuji Itose ,  Kinya Uchihashi ,  Yoichi Nakamura ,  Kohei Sugitani

    发明人： Sachiko UEDA ,  Yusuke Mori ,  Hiroyuki Ohashi ,  Yuji Itose ,  Kinya Uchihashi ,  Yoichi Nakamura ,  Kohei Sugitani

    IPC分类号： G01N33/48 ,  G01N1/28 ,  B01L3/00

    CPC分类号： B01L3/0293 ,  B01L3/527 ,  B01L9/00 ,  B01L2200/185 ,  B01L2300/021 ,  G01N35/1002

    摘要： A reagent container set is disclosed which comprises: a first reagent container for accommodating a first reagent to be used in a sample analyzer, the top part of the first reagent container having a first aspiration opening for inserting a first reagent aspirating tube to aspirate the first reagent; a waste fluid container for accommodating the first reagent used in the sample analyzer as a waste fluid, the top of the waste fluid container having a discharge opening for inserting a waste fluid discharging tube to discharge the waste fluid into the waste fluid container; a box for accommodating the first reagent container and the waste fluid container; and a container holding member for holding the first reagent container and the waste fluid container so that the first aspiration opening and the discharge opening are disposed at predetermined positions, the container holding member being maintained at a predetermined position within the box.

    摘要翻译： 公开了一种试剂容器组，其包括：第一试剂容器，用于容纳待用于样本分析仪的第一试剂，所述第一试剂容器的顶部具有用于插入第一试剂抽吸管的第一抽吸开口， 试剂; 用于将用于样品分析器中的第一试剂用作废液的废液容器，废液容器的顶部具有用于插入废液排放管的排出口，以将废液排放到废液容器中; 用于容纳第一试剂容器和废液容器的箱体; 以及容器保持构件，用于保持第一试剂容器和废液容器，使得第一抽吸开口和排出口设置在预定位置，容器保持构件保持在箱内的预定位置。

    Reagent for partially lysing a cell membrane of a red blood cell, a reagent for detecting malaria infected red blood cells, and a sample analyzing method for detecting malaria infected red blood cells
    5.
    发明授权
    Reagent for partially lysing a cell membrane of a red blood cell, a reagent for detecting malaria infected red blood cells, and a sample analyzing method for detecting malaria infected red blood cells 有权
    用于部分裂解红细胞的细胞膜的试剂，用于检测疟疾感染的红细胞的试剂和用于检测疟疾感染的红细胞的样品分析方法

    公开(公告)号：US07354775B2

    公开(公告)日：2008-04-08

    申请号：US11390298

    申请日：2006-03-28

    申请人： Ayumu Yoshida ,  Kinya Uchihashi ,  Yuji Itose ,  Aya Konishi ,  Hiromitsu Iizuka

    发明人： Ayumu Yoshida ,  Kinya Uchihashi ,  Yuji Itose ,  Aya Konishi ,  Hiromitsu Iizuka

    IPC分类号： G01N33/555

    CPC分类号： G01N33/80 ,  G01N33/56905 ,  Y02A50/58

    摘要： A reagent for partially lysing a cell membrane of a red blood cell infected with a malaria parasite, comprising: a first surfactant which has predetermined lysing ability for the red blood cell membrane; and a second surfactant which has weaker lysing ability than that of the first surfactant; wherein the reagent has pH of 5 to 7 and osmotic pressure of 200 to 300 mOsm/kg·H2O; and wherein the reagent partially lyses the malaria infected red blood cell membrane such that a malaria parasite is retained in the red blood cell and fluorescent dye passes through the cell membrane, is disclosed. A reagent for detecting malaria infected red blood cells, and a sample analyzing method for detecting malaria infected red blood cells, are also disclosed.

    摘要翻译： 一种用于部分溶解感染疟原虫的红细胞的细胞膜的试剂，其包含：对红细胞膜具有预定的裂解能力的第一表面活性剂; 和具有比第一表面活性剂弱的裂解能力的第二表面活性剂; 其中所述试剂的pH为5至7，渗透压为200至300mOsm / kg.H 2 O; 并且其中所述试剂部分地裂解疟疾感染的红细胞膜，使得疟原虫被保留在红细胞中，荧光染料通过细胞膜。 还公开了用于检测疟疾感染的红细胞的试剂和用于检测疟疾感染的红细胞的样品分析方法。

    Blood analyzing method and blood analyzer
    6.
    发明申请
    Blood analyzing method and blood analyzer 审中-公开
    血液分析方法和血液分析仪

    公开(公告)号：US20070020721A1

    公开(公告)日：2007-01-25

    申请号：US11491352

    申请日：2006-07-21

    申请人： Ayumu Yoshida ,  Yuji Itose ,  Kinya Uchihashi

    发明人： Ayumu Yoshida ,  Yuji Itose ,  Kinya Uchihashi

    IPC分类号： C12Q1/04

    CPC分类号： G01N15/1459 ,  G01N2015/008 ,  G01N2015/0088 ,  G01N2015/1486

    摘要： A blood analyzing method is described that includes steps of: preparing a measurement sample by hemolyzing red blood cells in a blood specimen, the measurement sample containing particles; irradiating a light on the measurement sample to detect two or more types of optical information reflecting characters of the particles in the measurement sample, thereby acquiring data indicating light intensities of the respective optical information as a particle data associated with each of the particles; counting white blood cells based on the particle data; outputting the result of counting white blood cells; determining whether malarial parasites are present or not based on the particle data; and outputting the result of determining. A blood analyzer also described.

    摘要翻译： 描述了一种血液分析方法，其包括以下步骤：通过溶血血样中的红细胞来制备测量样品，所述测量样品含有颗粒; 在测量样品上照射光以检测反映测量样本中的颗粒的字符的两种或更多种类型的光学信息，从而获取指示各个光学信息的光强度的数据，作为与每个颗粒相关联的粒子数据; 基于粒子数据计数白细胞; 输出白细胞计数结果; 基于粒子数据确定疟疾寄生虫是否存在; 并输出确定结果。 血液分析仪也有描述。

    Diluting reagent and method compelling time-independent consistency in MCV assay
    7.
    发明授权
    Diluting reagent and method compelling time-independent consistency in MCV assay 有权
    稀释试剂和方法在MCV测定中引人注目的时间依赖性一致性

    公开(公告)号：US06225124B1

    公开(公告)日：2001-05-01

    申请号：US09323689

    申请日：1999-06-02

    申请人： Berend Houwen ,  Kinya Uchihashi ,  Yukio Hamaguchi ,  Rolf Mast

    发明人： Berend Houwen ,  Kinya Uchihashi ,  Yukio Hamaguchi ,  Rolf Mast

    IPC分类号： G01N3348

    CPC分类号： G01N33/5094 ,  G01N15/12 ,  Y10T436/10 ,  Y10T436/101666 ,  Y10T436/108331 ,  Y10T436/2525 ,  Y10T436/25625

    摘要： Aqueous blood-sample diluting reagent and method of its use for compelling a morphological change in a blood sample to yield an MCV value assayed at elapsed time after the sample is drawn to be consistent within a diagnostically acceptable range with the original, immediate post-drawing MCV value. Selection of a small amount of a predetermined surfactant added within a limited range of concentration, and of a salt for adjusting osmotic pressure of the sample is thereby determined. The blood sample is treated with an anti-coagulant agent immediately post-drawing, and for assay in a particle analyzer at post-drawing elapsed time is diluted with the reagent solution. The reagent has an osmotic pressure (&pgr;) of approximately 150-400 mOsm/kg and a pH of 6.0-8.5. The surfactant is present in a 0.0005% to 0.5% concentration and has a hydrophile-lipophile balance (HLB) of 10-20.

    摘要翻译： 水性血液样品稀释试剂及其用于强制血液样品中形态学变化的方法，以产生在样品抽出后经过时间测定的MCV值，使其在诊断上可接受的范围内与原始的立即后绘图 MCV值。 由此确定少量在有限浓度范围内加入的预定表面活性剂和用于调节样品渗透压的盐的选择。 血液样品立即在拉伸后用抗凝剂处理，并且在抽出后经过时间的粒子分析仪中用试剂溶液稀释。 试剂的渗透压（pI）为约150-400mOsm / kg，pH为6.0-8.5。 表面活性剂的浓度为0.0005％至0.5％，亲水亲油平衡（HLB）为10-20。

    BLOOD ANALYZER, BLOOD ANALYSIS METHOD, HEMOLYTIC AGENT AND STAINING AGENT
    9.
    发明申请
    BLOOD ANALYZER, BLOOD ANALYSIS METHOD, HEMOLYTIC AGENT AND STAINING AGENT 有权
    血液分析仪，血液分析方法，HEMOLYTIC AGENT AND STAINING AGENT

    公开(公告)号：US20110053212A1

    公开(公告)日：2011-03-03

    申请号：US12942752

    申请日：2010-11-09

    申请人： Hideaki Matsumoto ,  Kinya Uchihashi ,  Yuji Itose ,  Aya Konishi ,  Ayumu Yoshida

    发明人： Hideaki Matsumoto ,  Kinya Uchihashi ,  Yuji Itose ,  Aya Konishi ,  Ayumu Yoshida

    IPC分类号： C12Q1/04 ,  C12M1/34

    CPC分类号： C12Q1/68 ,  G01N33/5094 ,  G01N33/56905 ,  G01N2333/44 ,  Y02A50/58

    摘要： This blood analyzer includes a sample preparation portion preparing a first measurement sample containing a blood sample and a hemolytic agent and a second measurement sample containing the blood sample, the same hemolytic agent as the hemolytic agent and a staining agent and a control portion classifying white blood cells in the first measurement sample into at least four groups of monocytes, neutrophils, eosinophils and others on the basis of fluorescent information and two types of scattered light information generated by a light information generation portion and classifying blood cells in the second measurement sample into at least malaria-infected red blood cells and others on the basis of fluorescent information and scattered light information generated by the light information generation portion.

    摘要翻译： 该血液分析装置具备准备含有血液试样和溶血剂的第一测定试样和含有血液试样的第二测定试样，与溶血剂相同的溶血剂和染色剂的试样调制部以及白血病分级对照部 基于荧光信息和由光信息生成部生成的两种类型的散射光信息将第一测量样品中的细胞分成至少四组单核细胞，嗜中性粒细胞，嗜酸性粒细胞等，并将第二测量样品中的血细胞分类为 基于由光信息生成部生成的荧光信息和散射光信息，最少疟疾感染的红细胞等。

    Reagent for measurement of leukocytes and hemoglobin concentration in blood
    10.
    再颁专利
    Reagent for measurement of leukocytes and hemoglobin concentration in blood 有权
    用于测量血液中白细胞和血红蛋白浓度的试剂

    公开(公告)号：USRE38131E1

    公开(公告)日：2003-06-03

    申请号：US09977768

    申请日：2001-10-15

    申请人： Kinya Uchihashi ,  Yoshiro Ikeuchi ,  Atsushi Shirakami ,  Yukio Hamaguchi

    发明人： Kinya Uchihashi ,  Yoshiro Ikeuchi ,  Atsushi Shirakami ,  Yukio Hamaguchi

    IPC分类号： G01N3100

    CPC分类号： G01N33/5094 ,  G01N33/721 ,  Y10T436/10 ,  Y10T436/101666 ,  Y10T436/107497 ,  Y10T436/108331 ,  Y10T436/25 ,  Y10T436/25125 ,  Y10T436/2525

    摘要： A reagent for measurement of leukocytes and hemoglobin concentration in the blood includes a cationic surfactant in an amount sufficient to lyse erythrocytes and denature hemoglobin, at least one of the following hemoglobin stabilizers: (a) sulfosalicylic acid, or its salt, in an amount effective for promoting the conversion of hemoglobin into methemoglobin, (b) 0.2 to 10.0 g/L of a water-soluble chelating agent having a nitrogen atom and a carboxyl group, and (c) piperazine, or its salt, in an amount effective for promoting the conversion of hemoglobin into methemoglobin, and a buffer for maintaining pH at 4 to 6.

    摘要翻译： 白血球的测定用试剂和血液中的血红蛋白浓度包括阳离子表面活性剂，其量足以溶解红细胞，变性血红蛋白，以下血红蛋白稳定剂中的至少一种：（a）磺基水杨酸或其盐，有效量 用于促进血红蛋白转化成高铁血红蛋白，（b）0.2〜10.0g / L的具有氮原子和羧基的水溶性螯合剂，和（c）哌嗪或其盐，其量有效促进 将血红蛋白转化为高铁血红蛋白，以及将pH保持在4至6的缓冲液。