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公开(公告)号:US20220265998A1
公开(公告)日:2022-08-25
申请号:US17622561
申请日:2020-06-05
Applicant: Verily Life Sciences LLC
Inventor: Benjamin K. Yaffe , Ken Rys , Bo Lu
Abstract: The present disclosure relates to connectors for high density neural interfaces and methods of microfabricating the connectors. Particularly, aspects of the present disclosure are directed to a connector having a main body, a first plug extending from the main body, a flexible bridge extending from the main body or the first plug, and a second plug extending from the flexible bridge. This structure allows for the main body, the first plug, and the second plug to be arranged in tandem on a longitudinal axis of the main body, which enables the connector to be passed through a narrow diameter cannula. This structure also allows for the first plug and the second plug to be arranged in a spread out orientation, which enables the connector to be electrically connected with a neurostimulator.
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公开(公告)号:US20220212016A1
公开(公告)日:2022-07-07
申请号:US17605493
申请日:2020-04-14
Applicant: Verily Life Sciences LLC
Inventor: Benjamin K. Yaffe , Bo Lu
IPC: A61N1/375 , A61N1/05 , H01B3/30 , H01B3/42 , H01R13/6598 , H01R13/642 , H01R24/58
Abstract: The present disclosure relates to connectors for high density neural interfaces and methods of microfabricating the connectors. Particularly, aspects of the present disclosure are directed to a connector having a core and a supporting structure wrapped around at least a portion of the core. The supporting structure may have a first layer of a high temperature liquid crystal polymer, and the second layer of a low temperature liquid crystal polymer that is reflowed to attach the supporting structure to the core. Conductive traces are buried between the first layer and the second layer, and the conductive traces terminate at conductive contacts formed on a surface of the first layer. The connector may have a predetermined shape or profile, which facilitates alignment and insertion of the connector into a header of a neurostimulator.
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公开(公告)号:US20190201154A1
公开(公告)日:2019-07-04
申请号:US16230337
申请日:2018-12-21
Applicant: Verily Life Sciences LLC
Inventor: Benjamin K. Yaffe
IPC: A61B90/00
CPC classification number: A61B90/08 , A61B17/02 , A61B17/0218 , A61B2017/00283 , A61B2017/00557 , A61B2017/00946 , A61B2017/0212 , A61B2017/12004 , A61B2090/036 , A61B2090/08021 , A61B2090/0815 , A61B2090/0817
Abstract: The present disclosure relates to devices and methods for partly isolating a target biological structure. The device may include a main body comprising a front face and a rear face, the main body having a proximal end and a distal end. The distal end may be arcuate in a first state and may be substantially planar in a second state. The device may further include one or more balloons disposed on the distal end of the main body. Each of the one or more balloons is deflated in the first state and each of the one or more balloons is inflated in the second state. The distal end of the main body is configured to deform to be substantially planar when each of the one or more balloons are inflated in the second state.
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公开(公告)号:US12172000B2
公开(公告)日:2024-12-24
申请号:US17622561
申请日:2020-06-05
Applicant: Verily Life Sciences LLC
Inventor: Benjamin K. Yaffe , Ken Rys , Bo Lu
Abstract: The present disclosure relates to connectors for high density neural interfaces and methods of microfabricating the connectors. Particularly, aspects of the present disclosure are directed to a connector having a main body, a first plug extending from the main body, a flexible bridge extending from the main body or the first plug, and a second plug extending from the flexible bridge. This structure allows for the main body, the first plug, and the second plug to be arranged in tandem on a longitudinal axis of the main body, which enables the connector to be passed through a narrow diameter cannula. This structure also allows for the first plug and the second plug to be arranged in a spread out orientation, which enables the connector to be electrically connected with a neurostimulator.
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公开(公告)号:US20210100633A1
公开(公告)日:2021-04-08
申请号:US17127494
申请日:2020-12-18
Applicant: Verily Life Sciences LLC
Inventor: Benjamin K. Yaffe
Abstract: The present disclosure relates to devices and methods for partly isolating a target biological structure. The device may include a main body comprising a front face and a rear face, the main body having a proximal end and a distal end. The distal end may be arcuate in a first state and may be substantially planar in a second state. The device may further include one or more balloons disposed on the distal end of the main body. Each of the one or more balloons is deflated in the first state and each of the one or more balloons is inflated in the second state. The distal end of the main body is configured to deform to be substantially planar when each of the one or more balloons are inflated in the second state.
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公开(公告)号:US20190200995A1
公开(公告)日:2019-07-04
申请号:US16230350
申请日:2018-12-21
Applicant: Verily Life Sciences LLC
Inventor: Benjamin K. Yaffe , Cindy Au , Eric Erwin
CPC classification number: A61B17/11 , A61B17/0218 , A61B17/1204 , A61B17/12136 , A61B17/3421 , A61B17/3423 , A61B17/3474 , A61B2017/00557 , A61B2017/00778 , A61B2017/00946 , A61B2017/1107 , A61B2017/12004 , A61B2017/320048 , A61B2090/0815 , A61B2090/0816 , A61M2025/0175
Abstract: The present disclosure relates to a method for installing a cuff around a target biological structure. The method may include inserting a guidewire through an incision in a patient underneath an exterior surface of a target biological structure, guiding a ramp device over the guidewire to a position underneath the target biological structure such that the target biological structure is partly supported by the ramp device, guiding a cuff deployment tool over the guidewire to the ramp device, the cuff deployment tool comprising an interior volume and a cuff positioned within the interior volume, and causing the cuff from the cuff deployment tool to deploy such that the cuff moves from within the interior volume to an extended position. At least part of the cuff is positioned between the ramp device and the target biological structure in the extended position.
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公开(公告)号:US12193885B2
公开(公告)日:2025-01-14
申请号:US17127494
申请日:2020-12-18
Applicant: Verily Life Sciences LLC
Inventor: Benjamin K. Yaffe
Abstract: The present disclosure relates to devices and methods for partly isolating a target biological structure. The device may include a main body comprising a front face and a rear face, the main body having a proximal end and a distal end. The distal end may be arcuate in a first state and may be substantially planar in a second state. The device may further include one or more balloons disposed on the distal end of the main body. Each of the one or more balloons is deflated in the first state and each of the one or more balloons is inflated in the second state. The distal end of the main body is configured to deform to be substantially planar when each of the one or more balloons are inflated in the second state.
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公开(公告)号:US12053636B2
公开(公告)日:2024-08-06
申请号:US17605493
申请日:2020-04-14
Applicant: Verily Life Sciences LLC
Inventor: Benjamin K. Yaffe , Bo Lu
IPC: A61N1/37 , A61N1/05 , A61N1/375 , H01B3/30 , H01B3/42 , H01R13/642 , H01R13/6598 , H01R24/58 , H01R107/00
CPC classification number: A61N1/3752 , A61N1/0531 , A61N1/0534 , A61N1/0551 , H01B3/305 , H01B3/306 , H01B3/307 , H01B3/427 , H01R13/642 , H01R13/6598 , H01R24/58 , H01R2107/00
Abstract: The present disclosure relates to connectors for high density neural interfaces and methods of microfabricating the connectors. Particularly, aspects of the present disclosure are directed to a connector having a core and a supporting structure wrapped around at least a portion of the core. The supporting structure may have a first layer of a high temperature liquid crystal polymer, and the second layer of a low temperature liquid crystal polymer that is reflowed to attach the supporting structure to the core. Conductive traces are buried between the first layer and the second layer, and the conductive traces terminate at conductive contacts formed on a surface of the first layer. The connector may have a predetermined shape or profile, which facilitates alignment and insertion of the connector into a header of a neurostimulator.
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公开(公告)号:US10898289B2
公开(公告)日:2021-01-26
申请号:US16230337
申请日:2018-12-21
Applicant: Verily Life Sciences LLC
Inventor: Benjamin K. Yaffe
Abstract: The present disclosure relates to devices and methods for partly isolating a target biological structure. The device may include a main body comprising a front face and a rear face, the main body having a proximal end and a distal end. The distal end may be arcuate in a first state and may be substantially planar in a second state. The device may further include one or more balloons disposed on the distal end of the main body. Each of the one or more balloons is deflated in the first state and each of the one or more balloons is inflated in the second state. The distal end of the main body is configured to deform to be substantially planar when each of the one or more balloons are inflated in the second state.
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公开(公告)号:US11540734B2
公开(公告)日:2023-01-03
申请号:US16551362
申请日:2019-08-26
Applicant: Verily Life Sciences LLC
Inventor: Derek DeBusschere , Benjamin K. Yaffe , Shannon Fong
IPC: A61B5/022 , A61B5/024 , A61B5/0205 , A61B5/021
Abstract: An apparatus for measuring a performance metric of a heart includes a housing, a tactile sensor, a finger clamp, a linear actuator, and a controller. The tactile sensor measures blood pressure pulsatility in a digital artery of a finger via applanation tonometry and outputs pulsatility signals indicative of the blood pressure pulsatility. The finger clamp extends from the housing to clamp the finger against the tactile sensor with the digital artery aligned over the tactile sensor. The linear actuator drives the finger clamp with a clamping force directed along a linear path. The controller is coupled to the tactile sensor and the linear actuator to control the clamping force and to generate pulsatility data, based upon the pulsatility signals, from which the performance metric of the heart may be determined.
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