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    Viral Vectors with Improved Properties
    1.
    发明申请
    Viral Vectors with Improved Properties 审中-公开
    具有改进性质的病毒载体

    公开(公告)号：US20120220492A1

    公开(公告)日：2012-08-30

    申请号：US13247860

    申请日：2011-09-28

    Applicant: Thomas Weber ,  Laure Gigout

    Inventor： Thomas Weber ,  Laure Gigout

    IPC: C40B40/08 ,  C40B50/00 ,  C12N15/864 ,  C12Q1/70 ,  C12N5/071 ,  C12N15/86 ,  C40B40/02 ,  C40B50/06

    CPC classification number: C12N15/86 ,  A61K48/0091 ,  C12N7/00 ,  C12N2750/14123 ,  C12N2750/14143 ,  C12N2750/14145 ,  C12N2810/40 ,  C12N2810/405 ,  C12N2810/60 ,  C12N2810/6072 ,  C12N2810/80 ,  C12N2810/85 ,  C12N2810/851 ,  C12N2810/854 ,  C12N2810/859 ,  C12N2830/42 ,  C12N2840/44

    Abstract: Methods to improve the tropism or other features of a virus are disclosed. Such methods can be used to prepare, e.g., DNA or plasmid libraries of variants of a gene encoding a viral capsid or envelope protein having a randomly inserted restriction site, libraries of viral clones with such variant genes with a randomly inserted restriction site or polypeptide sequence targeting a receptor expressed by a specific type of mammalian cells. Described are also methods to prepare mosaic viruses, i.e., viral particles wherein copies of one or more capsid or envelope proteins originate from different sources. These methods can be used to prepare mosaic viruses of a specific mixture of wild-type and mutant proteins, or of different types of mutant proteins.

    Abstract translation: 公开了改善病毒向性或其他特征的方法。 这样的方法可用于制备例如编码具有随机插入的限制性位点的病毒衣壳或包膜蛋白的基因的变体的DNA或质粒文库，具有随机插入的限制性位点或多肽序列的具有这种变体基因的病毒克隆的文库 靶向由特定类型的哺乳动物细胞表达的受体。 还描述了制备花叶病毒的方法，即病毒颗粒，其中一种或多种衣壳或包膜蛋白的拷贝来源于不同的来源。 这些方法可用于制备野生型和突变蛋白或不同类型的突变蛋白的特异性混合物的花叶病毒。

    Viral vectors with improved properties
    2.
    发明申请
    Viral vectors with improved properties 审中-公开
    具有改善性质的病毒载体

    公开(公告)号：US20060286545A1

    公开(公告)日：2006-12-21

    申请号：US10558394

    申请日：2004-05-24

    Applicant: Thomas Weber ,  Laure Gigout

    Inventor： Thomas Weber ,  Laure Gigout

    IPC: C40B30/06 ,  C40B40/08 ,  C12N15/86

    CPC classification number: C12N15/86 ,  A61K48/0091 ,  C12N7/00 ,  C12N2750/14123 ,  C12N2750/14143 ,  C12N2750/14145 ,  C12N2810/40 ,  C12N2810/405 ,  C12N2810/60 ,  C12N2810/6072 ,  C12N2810/80 ,  C12N2810/85 ,  C12N2810/851 ,  C12N2810/854 ,  C12N2810/859 ,  C12N2830/42 ,  C12N2840/44

    Abstract: Methods to improve the tropism or other features of a virus is disclosed. Such methods can be used to prepare, e.g., DNA or plasmid libraries of variants of a gene encoding a viral capsid or envelope restriction site, libraries of viral clones with such variant genes with a randon-dy inserted restriction site or polypeptide sequence targeting a receptor expressed by a specific type of mammalian cells. Described are also methods to prepare mosaic viruses, i.e., viral particles wherein copies of one or more capsid or envelope proteins originate from different sources. These methods can be used to prepare mosaic viruses of a specific mixture of wild-type and mutant proteins, or of different types of mutant proteins.

    Abstract translation: 公开了改善病毒的向性或其他特征的方法。 这样的方法可以用于制备例如编码病毒衣壳或包膜限制性位点的基因的变体的DNA或质粒文库，具有这样的变体基因的病毒克隆的文库与插入限制性位点或靶向受体的多肽序列 由特定类型的哺乳动物细胞表达。 还描述了制备花叶病毒的方法，即病毒颗粒，其中一种或多种衣壳或包膜蛋白的拷贝来源于不同的来源。 这些方法可用于制备野生型和突变蛋白或不同类型的突变蛋白的特异性混合物的花叶病毒。

    Motor vehicle device
    3.
    发明授权
    Motor vehicle device 有权
    机动车装置

    公开(公告)号：US09352657B2

    公开(公告)日：2016-05-31

    申请号：US13996942

    申请日：2011-11-16

    Applicant: Karlheinz Baier ,  Matthias Kronewitter ,  Thomas Weber

    Inventor： Karlheinz Baier ,  Matthias Kronewitter ,  Thomas Weber

    IPC: H02J7/00 ,  B60L11/18

    CPC classification number: B60L11/1809 ,  B60L11/1816 ,  B60L11/182 ,  B60L11/1846 ,  B60L11/1848 ,  Y02T10/7005 ,  Y02T10/7072 ,  Y02T90/121 ,  Y02T90/122 ,  Y02T90/128 ,  Y02T90/14 ,  Y02T90/163 ,  Y02T90/169 ,  Y04S30/14

    Abstract: An electrical and/or hybrid motor vehicle device includes a charging device for the charging of an accumulator device. The charging device includes a first charging unit with a connector element for the charging of the accumulator device, which is provided for energy transfer by means of contacts. The charging device also includes a second charging unit with an energy transfer unit for the charging of the accumulator device, which is provided for a contactless energy transfer. The charging device has a charging electronic system, which is provided at least in part as an integral construction with the first and second charging units.

    Abstract translation: 电动和/或混合动力车辆装置包括用于对蓄电装置进行充电的充电装置。 充电装置包括具有用于蓄电装置的充电的连接器元件的第一充电单元，其被提供用于通过触点的能量传递。 充电装置还包括具有用于蓄电装置的充电的能量传递单元的第二充电单元，其被提供用于非接触式能量传递。 充电装置具有充电电子系统，其至少部分地作为与第一充电单元和第二充电单元一体的结构。

    Vehicle seat, in particular commercial vehicle seat
    5.
    发明授权
    Vehicle seat, in particular commercial vehicle seat 有权
    车辆座椅，特别是商用车座椅

    公开(公告)号：US08544813B2

    公开(公告)日：2013-10-01

    申请号：US13130428

    申请日：2010-06-24

    Applicant: Viktor Enns ,  Thomas Weber ,  Thomas Gundall

    Inventor： Viktor Enns ,  Thomas Weber ,  Thomas Gundall

    IPC: F16M13/00 ,  A47C1/00

    CPC classification number: B60N2/508 ,  B60N2/509

    Abstract: A vehicle seat, particularly a commercial-vehicle seat is provided with a scissor-type stand (3) which is able to vibrate and which is provided with a top frame (7), two first rocker arms (8a) and two second rocker arms (8b), which intersect in pairs at a scissor axis (10) extending in a transverse seat direction (y). The first two rocker arms (8a) are connected with one another at one end via a transverse tube (18) which extends in the transverse seat direction (y) and are pivotably mounted on the top frame (7) and able to vibrate in the longitudinal seat direction (x) via a bearing mechanism (20). The transverse tube (18) can be locked with the top frame (7) via at least one locking device (31).

    Abstract translation: 车辆座椅，特别是商用车座具有能够振动的剪刀式支架（3），并且设置有顶架（7），两个第一摇臂（8a）和两个第二摇臂 （8b），其在沿横向座椅方向（y）延伸的剪刀轴线（10）成对地相交。 前两个摇臂（8a）在一端通过横向管（18）彼此连接，横向管（18）在横向座椅方向（y）上延伸并且可枢转地安装在顶架（7）上并且能够在 纵向座椅方向（x）经由轴承机构（20）。 横管（18）可以经由至少一个锁定装置（31）与顶框架（7）锁定。

    Optoelectronic sensor device for a motor vehicle
    9.
    发明授权
    Optoelectronic sensor device for a motor vehicle 有权
    汽车用光电传感器装置

    公开(公告)号：US07414237B2

    公开(公告)日：2008-08-19

    申请号：US11640684

    申请日：2006-12-18

    Applicant: Matthias Richwin ,  Thomas Weber

    Inventor： Matthias Richwin ,  Thomas Weber

    IPC: G02B6/42 ,  H01J5/02 ,  G01N15/06

    CPC classification number: G01N21/552 ,  B60S1/0822 ,  B60S1/0833

    Abstract: A sensor for detecting moisture on a pane includes a coupler having prisms arranged in coupling areas for coupling light from a transmitter into the pane at an input angle and prisms arranged in decoupling areas for decoupling light reflected from the pane to a receiver at a corresponding output angle. The prisms in the coupling areas have prism surfaces perpendicular to the input angle and the prisms in the decoupling areas have prism surfaces perpendicular to the output angle. Each prism includes a prism flank. The prism flanks in the decoupling areas may be arranged parallel to the output angle. Some of the prism flanks in the decoupling areas are opaque or roughened. Alternatively, some of the prism flanks in the decoupling areas are tilted from running parallel to the output angle. Alternatively, some of the prism flanks in the decoupling areas include at least one additional superimposed prism.

    Abstract translation: 用于检测窗格上的水分的传感器包括耦合器，其具有布置在耦合区域中的棱镜，用于将来自发射器的光以输入角度耦合到窗格中，并且布置在去耦区域中的棱镜，用于将从窗格反射的光去耦到相应输出端处的接收器 角度。 耦合区域中的棱镜具有垂直于输入角的棱镜表面，并且去耦区域中的棱镜具有垂直于输出角的棱镜表面。 每个棱镜包括棱镜。 去耦区域中的棱镜侧面可以平行于输出角度布置。 去耦区域中的一些棱镜侧面是不透明或粗糙的。 或者，解耦区域中的一些棱镜侧面平行于输出角度倾斜。 或者，解耦区域中的一些棱镜侧面包括至少一个附加的叠加棱镜。

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