公开(公告)号：US08529473B2

公开(公告)日：2013-09-10

申请号：US13560675

申请日：2012-07-27

Applicant: Michael Callahan ,  Thomas Coleman

Inventor： Michael Callahan ,  Thomas Coleman

IPC: A61B7/00

CPC classification number: G06F17/28 ,  A61B5/04886 ,  G10L13/00 ,  G10L13/043 ,  G10L15/24 ,  G10L25/48

Abstract: A method and apparatus are provided for processing a set of communicated signals associated with a set of muscles, such as the muscles near the larynx of the person, or any other muscles the person use to achieve a desired response. The method includes the steps of attaching a single integrated sensor, for example, near the throat of the person proximate to the larynx and detecting an electrical signal through the sensor. The method further includes the steps of extracting features from the detected electrical signal and continuously transforming them into speech sounds without the need for further modulation. The method also includes comparing the extracted features to a set of prototype features and selecting a prototype feature of the set of prototype features providing a smallest relative difference.

公开(公告)号：US07590350B2

公开(公告)日：2009-09-15

申请号：US10653632

申请日：2003-09-02

Applicant: Gregory Moffatt ,  Joanne Wakefield ,  Thomas Coleman ,  Mark Riley ,  Charles Hubbard

Inventor： Gregory Moffatt ,  Joanne Wakefield ,  Thomas Coleman ,  Mark Riley ,  Charles Hubbard

IPC: H04B10/08 ,  H04J14/02

CPC classification number: H04J14/0227 ,  H04J14/0221 ,  H04J14/0246 ,  H04J14/025 ,  H04J14/0283

Abstract: A computerized method for modifying an optical wavelength division multiplexing (WDM) network is described. The method includes providing an initial configuration of the optical WDM network. At least one parameter that represents a characteristic of a span in the optical WDM network as defined by the initial configuration is evaluated. The initial configuration of the optical WDM network is modified in response to the evaluation. The method can also include determining if a predetermined set of engineering rules are satisfied.

Abstract translation: 描述了用于修改光波分复用（WDM）网络的计算机化方法。 该方法包括提供光学WDM网络的初始配置。 评估表示由初始配置定义的光WDM网络中的跨度的特性的至少一个参数。 响应于评估，光学WDM网络的初始配置被修改。 该方法还可以包括确定是否满足预定的一组工程规则。

公开(公告)号：US20080010206A1

公开(公告)日：2008-01-10

申请号：US11821840

申请日：2007-06-26

Applicant: Thomas Coleman

Inventor： Thomas Coleman

IPC: H04K1/00

CPC classification number: G06Q10/00 ,  G06F21/6254 ,  G06Q10/10 ,  G06Q30/02 ,  G06Q30/0269 ,  G06Q50/265

Abstract: A method and system for asserting control over and protecting the privacy of individuals' personal and transactional information, to prevent unauthorized use thereof, and permit limited use thereof, with compensation, to the extent permitted the individual. Privacy notices are given in printed and electronic form to other parties involved in the individuals' transactions. The individuals' own data are collected and maintained in a privacy trust database. On a voluntary basis, abstracted, anonymous profile information can be made available to advertisers, in exchange for compensation to the individuals. One use is in a content broadcasting system, where receipt of profile based viewer-specific commercial messages provide financial compensation for the cost of user-selected content received by the individual.

Abstract translation: 一种方法和系统，用于控制和保护个人的个人和交易信息的隐私，防止未经授权的使用，并允许有限的使用，在个人允许的范围内进行补偿。 隐私声明以印刷和电子形式发送给个人交易的其他各方。 个人自己的数据被收集并维护在隐私信任数据库中。 在自愿的基础上，抽象的，匿名的个人资料信息可以提供给广告客户，以换取对个人的赔偿。 一种用途是在内容广播系统中，其中基于简档的观众专用商业消息的接收为由个人接收的用户选择的内容的成本提供经济补偿。

公开(公告)号：US20060216757A1

公开(公告)日：2006-09-28

申请号：US11259326

申请日：2005-10-25

Applicant: Michael Brines ,  Anthony Cerami ,  Thomas Coleman

Inventor： Michael Brines ,  Anthony Cerami ,  Thomas Coleman

IPC: C40B40/10 ,  G01N33/567 ,  G01N33/53

CPC classification number: A61K38/19 ,  A61K38/1793 ,  A61K38/1816 ,  C40B40/10 ,  G01N33/5032 ,  G01N2333/575 ,  G01N2333/72 ,  G01N2500/10 ,  G01N2500/20 ,  G01N2800/70 ,  A61K2300/00

Abstract: The present invention is directed methods for identifying compounds that have a tissue protective activity using a heteromultimer receptor complex that mediates the tissue protective activities. The complex consists of at least one EPO-R in complex with at least one βc Receptor. These compounds used in the assays to identify tissue protective compounds include, but are not limited to, small molecules and biologics. The compounds identified using these assays can be used to treat or prevent various diseases, disorders, or conditions of the central and peripheral nervous systems as well as those of other erythropoietin-responsive or excitable cells, tissues, and organs.

Abstract translation: 本发明涉及使用介导组织保护活性的异源多聚体受体复合物来鉴定具有组织保护活性的化合物的方法。 复合物由至少一个与至少一个β受体复合物的EPO-R组成。 用于鉴定组织保护性化合物的测定中使用的这些化合物包括但不限于小分子和生物制剂。 使用这些测定法鉴定的化合物可用于治疗或预防中枢和周围神经系统以及其它促红细胞生成素反应或兴奋细胞，组织和器官的各种疾病，病症或病症。

公开(公告)号：USD255362S

公开(公告)日：1980-06-10

申请号：US862049

申请日：1977-12-19

Applicant: Thomas Coleman

Designer： Thomas Coleman

公开(公告)号：US20180075019A1

公开(公告)日：2018-03-15

申请号：US15587121

申请日：2017-05-04

Applicant: Michael Callahan ,  Thomas Coleman

Inventor： Michael Callahan ,  Thomas Coleman

IPC: G06F17/28 ,  G10L13/04

CPC classification number: G06F17/28 ,  A61B5/04886 ,  G10L13/00 ,  G10L13/043 ,  G10L15/24 ,  G10L25/48

Abstract: A method and apparatus are provided for processing a set of communicated signals associated with a set of muscles, such as the muscles near the larynx of the person, or any other muscles the person use to achieve a desired response. The method includes the steps of attaching a single integrated sensor, for example, near the throat of the person proximate to the larynx and detecting an electrical signal through the sensor. The method further includes the steps of extracting features from the detected electrical signal and continuously transforming them into speech sounds without the need for further modulation. The method also includes comparing the extracted features to a set of prototype features and selecting a prototype feature of the set of prototype features providing a smallest relative difference.

公开(公告)号：US08716245B2

公开(公告)日：2014-05-06

申请号：US13278131

申请日：2011-10-20

Applicant: Anthony Cerami ,  Michael Brines ,  Thomas Coleman

Inventor： Anthony Cerami ,  Michael Brines ,  Thomas Coleman

IPC: C07K7/08 ,  A61K38/10 ,  A61K48/00

CPC classification number: C07K14/505 ,  A61K38/00 ,  C07K14/435 ,  C07K14/575 ,  C07K14/71 ,  C07K2319/00

Abstract: Provided herein are tissue protective peptides derived from or sharing consensus sequences with portions of cytokine receptor ligands, including Erythropoietin (EPO), that are generally located on or within the region of the cytokine receptor ligand that faces away from a receptor complex while the ligand is bound to the receptor. Also provide herein are fragments, chimeras, as well as peptides designed to mimic the spatial localization of key amino acid residues within the tissue protective receptor ligands, e.g., EPO; methods for treating or preventing a disease or disorder using tissue protective peptides; and methods for enhancing excitable tissue function using tissue protective peptides.

Abstract translation: 本文提供了组织保护肽，其衍生自或与共同序列共享，其中部分细胞因子受体配体包括促红细胞生成素（EPO），其通常位于远离受体复合物的细胞因子受体配体的区域上或内侧，而配体为 与受体结合。 本文还提供了片段，嵌合体以及旨在模拟组织保护性受体配体例如EPO中的关键氨基酸残基的空间定位的肽; 使用组织保护肽治疗或预防疾病或病症的方法; 以及使用组织保护肽增强可兴奋组织功能的方法。

公开(公告)号：US08251924B2

公开(公告)日：2012-08-28

申请号：US11825785

申请日：2007-07-09

Applicant: Michael Callahan ,  Thomas Coleman

Inventor： Michael Callahan ,  Thomas Coleman

IPC: A61B7/00

CPC classification number: G06F17/28 ,  A61B5/04886 ,  G10L13/00 ,  G10L13/043 ,  G10L15/24 ,  G10L25/48

Abstract: A method and apparatus are provided for processing a set of communicated signals associated with a set of muscles, such as the muscles near the larynx of the person, or any other muscles the person use to achieve a desired response. The method includes the steps of attaching a single integrated sensor, for example, near the throat of the person proximate to the larynx and detecting an electrical signal through the sensor. The method further includes the steps of extracting features from the detected electrical signal and continuously transforming them into speech sounds without the need for further modulation. The method also includes comparing the extracted features to a set of prototype features and selecting a prototype feature of the set of prototype features providing a smallest relative difference.

Abstract translation: 提供了一种方法和装置，用于处理与一组肌肉相关联的一组传播信号，例如人的喉部附近的肌肉，或者人们用于实现期望的反应的任何其他肌肉。 该方法包括以下步骤：附接单个集成传感器，例如靠近喉部的人的喉部，并通过传感器检测电信号。 该方法还包括以下步骤：从检测到的电信号中提取特征，并将其连续变换成语音，而不需要进一步的调制。 该方法还包括将所提取的特征与一组原型特征进行比较，并且选择提供最小相对差异的原始特征集的原型特征。

公开(公告)号：US20070234605A1

公开(公告)日：2007-10-11

申请号：US11278791

申请日：2006-04-05

Applicant: Thomas Coleman ,  William Schlotter ,  Princess Coleman ,  Ann Schlotter

Inventor： Thomas Coleman ,  William Schlotter ,  Princess Coleman ,  Ann Schlotter

IPC: G09F19/08

CPC classification number: G09F19/08 ,  A45D34/045 ,  A45D2034/007

Abstract: A lipstick or gloss applicator is provided with a container for lipstick or gloss that is attached to a brush handle. The container is closed with a conical slit wiper/scraper. The handle for the applicator has a cap for closing the container and houses a power source, motor and transmission for rotating an attached brush and parts of replicas of individuals, animals or objects and a light.

Abstract translation: 唇膏或光泽涂抹器具有附着于刷柄的唇膏或光泽的容器。 容器用锥形狭缝刮水器/刮板关闭。 用于涂抹器的手柄具有用于封闭容器的盖，并容纳用于旋转附着的刷子和个体，动物或物体的副本的一部分的电源，电动机和变速器。

公开(公告)号：US20060286675A1

公开(公告)日：2006-12-21

申请号：US11156714

申请日：2005-06-21

Applicant: Thomas Coleman ,  Frederick Wolf ,  James Bruya

Inventor： Thomas Coleman ,  Frederick Wolf ,  James Bruya

IPC: G01N33/00

CPC classification number: G01N33/2852 ,  G01N27/048 ,  G01N27/06 ,  G01N27/221 ,  G01N27/223 ,  G01N33/2847 ,  Y10T436/21 ,  Y10T436/218

Abstract: A method for assigning a grade to a liquid hydrocarbon fuel in relation to the potential for a water or water-based phase to form in said fuel is provided, said method comprising sensing the electrical resistance of the fuel; sensing the capacitance of the fuel; determining the amount of water or water-soluble compounds in said fuel wherein the step of determining the amount of water or water-soluble compounds includes the step of comparing the electrical resistance of the fuel to a plurality pre-determined values of electrical resistance corresponding to a plurality of concentrations of water or water-soluble compounds in the fuel; identifying which water-soluble compound or compounds are present in said fuel wherein the step of identifying which compound or compounds are present includes the step of comparing the capacitance to a plurality of pre-determined values of capacitance corresponding to a water or a plurality of water-soluble compounds that may be present; sensing the temperature of said fuel, and calculating the potential for a water or water-soluble phase to form in said fuel during anticipated temperature conditions of transportation or storage.

Abstract translation: 提供了一种用于将液位碳氢化合物燃料的等级分配给在所述燃料中形成的水​​或水基相的可能性的方法，所述方法包括感测燃料的电阻; 感测燃料的电容; 确定所述燃料中的水或水溶性化合物的量，其中确定水或水溶性化合物的量的步骤包括将燃料的电阻与多个预定值相对应的步骤 多种浓度的水或水溶性化合物在燃料中; 识别在所述燃料中存在哪些水溶性化合物或化合物，其中鉴定哪种化合物或化合物存在的步骤包括将电容与多个与水或多个水相对应的预定电容值进行比较的步骤 可能存在的可溶性化合物; 感测所述燃料的温度，并计算在运输或储存的预期温度条件下在所述燃料中形成水或水溶性相的可能性。