公开(公告)号：US20240398697A1

公开(公告)日：2024-12-05

申请号：US18696258

申请日：2022-09-29

Applicant: The University of Liverpool

Inventor： Steven Paul Rannard ,  Andrew Owen ,  Andrew Dwyer ,  Catherine Unsworth ,  James Hobson ,  Paul Curley ,  Joanne Sharp ,  Ryan Donnelly ,  Yara NASER

IPC: A61K9/00 ,  A61K31/454 ,  A61K31/498 ,  A61K45/06

Abstract: The present invention relates to solid compositions comprising microparticles of glecaprevir and/or pibrentasvir dispersed within a matrix comprising a first excipient and a second excipient. The present invention also relates to microneedle arrays, implantable rods, aqueous dispersions, and pharmaceutical compositions derived from said solid compositions and uses for the same.