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    Polymer poly (triphenylacrylonitrite) and synthesis thereof
    3.
    发明授权
    Polymer poly (triphenylacrylonitrite) and synthesis thereof 有权

    公开(公告)号：US10941243B2

    公开(公告)日：2021-03-09

    申请号：US16341260

    申请日：2017-10-09

    申请人： THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY

    发明人： Benzhong Tang ,  Zijie Qiu

    IPC分类号： C08G61/12 ,  C09K11/06 ,  C08G61/02 ,  G03F7/038 ,  G03F7/039

    摘要： A method is directed to synthesis of poly(triphenylacrylonitrite)s (PTPANs) comprising polycoupling dibromoarenes, internal diynes, and potassium ferrocyanide, resulting in polycoupled dibromoarenes, internal diynes, and potassium ferrocyanide; and producing poly(triphenylacrylonitrite)s (PTPANs) by catalysis of the polycoupled dibromoarenes, internal diynes, and potassium ferrocyanide with palladium acetate and sodium bicarbonate, wherein the catalysis is allowed to proceed in dimethylacetamide under nitrogen at a prescribed temperature for a prescribed time. Further, poly(triphenylacrylonitrite)s (PTPANs) is a polymer and comprises a backbone structure of wherein x and y are integers; wherein each R is independently selected from the group consisting of and wherein each R′ is independently selected from the group consisting of

    THERMOSETTING POLY(SILOXANE-DIPHENYLBUTADIYNE) WITH READILY TUNABLE GLASS TRANSITION TEMPERATURE AND HIGH THERMAL STABILITY
    5.
    发明申请
    THERMOSETTING POLY(SILOXANE-DIPHENYLBUTADIYNE) WITH READILY TUNABLE GLASS TRANSITION TEMPERATURE AND HIGH THERMAL STABILITY 有权
    热固性聚（硅氧烷 - 二苯乙烯），具有易燃玻璃过渡温度和高热稳定性

    公开(公告)号：US20150057421A1

    公开(公告)日：2015-02-26

    申请号：US14386972

    申请日：2013-04-07

    申请人： THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY

    发明人： Benzhong Tang ,  Jie Li ,  Rongrong Hu ,  Wing Yip Lam

    IPC分类号： C08G77/52

    CPC分类号： C08G77/52 ,  C09J183/14

    摘要： A poly(siloxane-diphenylbutadiyne) exhibiting thermosetting properties, a highly tunable glass transition temperature (Tg), and very high thermal and thermo-oxidative stability. In one embodiment, the poly(siloxane-diphenylbutadiyne) is a poly(tetrasiloxane-diphenylbutadiyne). The present subject matter also relates to a method of synthesizing the poly(tetrasiloxane-diphenylbutadiyne).

    摘要翻译： 显示出热固性，高可调玻璃化转变温度（Tg）和非常高的热和热氧化稳定性的聚（硅氧烷 - 二苯基丁二炔）。 在一个实施方案中，聚（硅氧烷 - 二苯基丁二炔）是聚（四硅氧烷 - 二苯基丁二炔）。 本主题还涉及合成聚（四硅氧烷 - 二苯基丁二炔）的方法。

    Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins
    9.
    发明授权
    Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins 有权
    用于监测和延缓淀粉样蛋白原纤维的水溶性AIE发光剂

    公开(公告)号：US09279806B2

    公开(公告)日：2016-03-08

    申请号：US14171957

    申请日：2014-02-04

    申请人： THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY

    发明人： Benzhong Tang ,  Yuning Hong ,  Sijie Chen ,  Tsz Kin Ryan Kwok ,  Wai Tung Leung

    IPC分类号： C12Q1/00 ,  G01N33/53 ,  G01N33/543 ,  G01N33/542 ,  G01N21/64 ,  G01N21/77

    CPC分类号： G01N33/542 ,  G01N2021/6432 ,  G01N2021/7786 ,  G01N2333/4709 ,  G01N2333/62

    摘要： Compounds that exhibit aggregation induced emission (AIE), and more particularly to water-soluble conjugated polyene compounds that exhibit aggregation induced emission. The conjugated polyene compounds can be used as bioprobes for DNA detection, G-quadruplex identification, and potassium-ion sensing. The polyenes also can be utilized as an external fluorescent marker to study conformational structures, to monitor folding processes of label-free oligonucleotides with G-rich strand sequences, and to visualize DNA bands in PAGE assay. The polyenes have applications in high-throughput anticancer drug screening and are useful for the development of efficient anti-cancer drugs. Furthermore, the present subject matter can also be used to monitor fibrillation of amyloid proteins and to facilitate the storage and delivery thereof.

    摘要翻译： 表现出聚集诱导发射（AIE）的化合物，更具体地说是表现出聚集诱导发射的水溶性共轭多烯化合物。 共轭多烯化合物可用作DNA检测，G-四链体鉴定和钾离子感测的生物探针。 多烯还可以用作外部荧光标记物来研究构象结构，监测具有富G链的序列的无标记寡核苷酸的折叠过程，并在PAGE测定中显现DNA条带。 多烯在高通量抗癌药物筛选中有应用，可用于开发有效的抗癌药物。 此外，本主题也可用于监测淀粉样蛋白的原纤维化并促进其储存和递送。