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公开(公告)号：US09265662B2
公开(公告)日：2016-02-23
申请号：US14527194
申请日：2014-10-29
Inventor： Michael P. Kilgard , Navzer Engineer , David Michael Pierce
CPC classification number: A61F11/00 , A61B5/128 , A61N1/0551 , A61N1/36036 , A61N1/36053 , A61N1/36092 , A61N1/361 , A61N1/36132 , A61N1/36167 , A61N1/36171 , A61N1/36178 , A61N1/37235 , A61N1/37247 , G06F19/00 , G09B23/28 , H04R25/75
Abstract: A method of treating tinnitus comprising measuring a patient's hearing, determining the patient's hearing loss and the patient's tinnitus frequency using the measurements of the patient's hearing, programming a clinical controller with the measurements of the patient's hearing, selecting a plurality of therapeutic tones, where the therapeutic tones are selected to be at least a half-octave above or below of the patient's tinnitus frequency, setting an appropriate volume for each of the plurality of tones, repetitively playing each of the plurality of therapeutic tones, and pairing a vagus nerve stimulation pulse train with each playing of a therapeutic tone, thereby reducing the patient's perception of tinnitus.
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2.发明授权Methods, systems, and devices for pairing vagus nerve stimulation with motor therapy in stroke patients 有权用于配对迷走神经刺激与中风患者运动疗法的方法，系统和装置公开(公告)号：US09533152B2
公开(公告)日：2017-01-03
申请号：US14550357
申请日：2014-11-21
Inventor： Michael P. Kilgard , Navzer Engineer , David Michael Pierce , Robert L. Rennaker
CPC classification number: A61N1/36067 , A61B5/1124 , A61N1/36003 , A61N1/36053 , A61N1/36092 , A61N1/361 , A61N1/36103 , A61N1/36132 , A61N1/36139 , A61N1/36178 , A61N1/37217 , A61N1/37235 , A61N1/37247 , A61N2/006 , A61N7/00 , A61N2007/0026 , G06F19/00 , G09B23/28
Abstract: A method of treating motor deficits in a stroke patient, comprising assessing a patient's motor deficits, determining therapeutic goals for the patient, based on the patient's motor deficits, selecting therapeutic tasks based on the therapeutic goals, performing each of the selected therapeutic tasks repetitively, observing the performance of the therapeutic tasks, initiating the stimulation of the vagus nerve manually at approximately a predetermined moment during the performance of the therapeutic tasks, stimulating the vagus nerve of the patient during the performance of the selected therapeutic tasks, and improving the patient's motor deficits.
Abstract translation: 一种治疗卒中患者的运动障碍的方法，包括评估患者的运动缺陷，基于患者运动障碍确定患者的治疗目标，基于治疗目标选择治疗任务，重复执行所选择的治疗任务， 观察治疗任务的性能，在执行治疗任务期间大约预定的时刻手动地启动迷走神经的刺激，在执行所选择的治疗任务期间刺激患者的迷走神经，并改善患者的运动 赤字。
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公开(公告)号：US09522274B2
公开(公告)日：2016-12-20
申请号：US14550286
申请日：2014-11-21
Inventor： Michael P. Kilgard , Navzer Engineer , David Michael Pierce , Robert L. Rennaker
CPC classification number: A61N1/36067 , A61B5/1124 , A61N1/36003 , A61N1/36053 , A61N1/36092 , A61N1/361 , A61N1/36103 , A61N1/36132 , A61N1/36139 , A61N1/36178 , A61N1/37217 , A61N1/37235 , A61N1/37247 , A61N2/006 , A61N7/00 , A61N2007/0026 , G06F19/00 , G09B23/28
Abstract: A method of treating motor deficits in a stroke patient, comprising assessing a patient's motor deficits, determining therapeutic goals for the patient, based on the patient's motor deficits, selecting therapeutic tasks based on the therapeutic goals, performing each of the selected therapeutic tasks repetitively, observing the performance of the therapeutic tasks, initiating the stimulation of the vagus nerve manually at approximately a predetermined moment during the performance of the therapeutic tasks, stimulating the vagus nerve of the patient during the performance of the selected therapeutic tasks, and improving the patient's motor deficits.
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公开(公告)号：US09345886B2
公开(公告)日：2016-05-24
申请号：US14497907
申请日：2014-09-26
Inventor： Michael P. Kilgard , Larry Cauller , Navzer Engineer , Christa McIntyre Rodriguez , Will Rosellini
CPC classification number: A61N1/36167 , A61F11/00 , A61M21/00 , A61M21/02 , A61M2021/0016 , A61M2021/0022 , A61M2021/0027 , A61M2021/0044 , A61M2021/0072 , A61M2021/0077 , A61M2205/3515 , A61M2230/06 , A61M2230/08 , A61M2230/10 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/50 , A61M2230/60 , A61M2230/65 , A61N1/36014 , A61N1/36053 , A61N1/36067 , A61N1/36082 , A61N1/36092 , A61N1/361 , A61N1/36103 , A61N1/36139 , A61N5/0618 , A61N5/0622 , G09B19/00 , G09B19/003 , G09B23/28 , H04R25/75
Abstract: Systems, methods and devices for paired training include timing controls so that training and neural stimulation can be provided simultaneously. Paired trainings may include therapies, rehabilitation and performance enhancement training. Stimulations of nerves such as the vagus nerve that affect subcortical regions such as the nucleus basalis, locus coeruleus or amygdala induce plasticity in the brain, enhancing the effects of a variety of therapies, such as those used to treat tinnitus, stroke, traumatic brain injury and post-traumatic stress disorder.
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公开(公告)号：US09265661B2
公开(公告)日：2016-02-23
申请号：US14286177
申请日：2014-05-23
Inventor： Michael P. Kilgard , Navzer Engineer , David Michael Pierce
CPC classification number: A61F11/00 , A61B5/128 , A61N1/0551 , A61N1/36036 , A61N1/36053 , A61N1/36092 , A61N1/361 , A61N1/36132 , A61N1/36167 , A61N1/36171 , A61N1/36178 , A61N1/37235 , A61N1/37247 , G06F19/00 , G09B23/28 , H04R25/75
Abstract: A method of treating tinnitus comprising measuring a patient's hearing, determining the patient's hearing loss and the patient's tinnitus frequency using the measurements of the patient's hearing, programming a clinical controller with the measurements of the patient's hearing, selecting a plurality of therapeutic tones, where the therapeutic tones are selected to be at least a half-octave above or below of the patient's tinnitus frequency, setting an appropriate volume for each of the plurality of tones, repetitively playing each of the plurality of therapeutic tones, and pairing a vagus nerve stimulation pulse train with each playing of a therapeutic tone, thereby reducing the patient's perception of tinnitus.
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Patent Agency Ranking
公开(公告)号：US09339654B2
公开(公告)日：2016-05-17
申请号：US14500325
申请日：2014-09-29
Inventor： Michael P. Kilgard , Larry Cauller , Navzer Engineer , Christa McIntyre Rodriguez , Will Rosellini
IPC: A61N1/00 , A61N1/36 , A61N5/06 , G09B19/00 , G09B23/28 , A61M21/02 , H04R25/00 , A61F11/00 , A61M21/00
CPC classification number: A61N1/36167 , A61F11/00 , A61M21/00 , A61M21/02 , A61M2021/0016 , A61M2021/0022 , A61M2021/0027 , A61M2021/0044 , A61M2021/0072 , A61M2021/0077 , A61M2205/3515 , A61M2230/06 , A61M2230/08 , A61M2230/10 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/50 , A61M2230/60 , A61M2230/65 , A61N1/36014 , A61N1/36053 , A61N1/36067 , A61N1/36082 , A61N1/36092 , A61N1/361 , A61N1/36103 , A61N1/36139 , A61N5/0618 , A61N5/0622 , G09B19/00 , G09B19/003 , G09B23/28 , H04R25/75
Abstract: Systems, methods and devices for paired training include timing controls so that training and neural stimulation can be provided simultaneously. Paired trainings may include therapies, rehabilitation and performance enhancement training. Stimulations of nerves such as the vagus nerve that affect subcortical regions such as the nucleus basalis, locus coeruleus or amygdala induce plasticity in the brain, enhancing the effects of a variety of therapies, such as those used to treat tinnitus, stroke, traumatic brain injury and post-traumatic stress disorder.
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公开(公告)号：US09265663B2
公开(公告)日：2016-02-23
申请号：US14527253
申请日：2014-10-29
Inventor： Michael P. Kilgard , Navzer Engineer , David Michael Pierce
CPC classification number: A61F11/00 , A61B5/128 , A61N1/0551 , A61N1/36036 , A61N1/36053 , A61N1/36092 , A61N1/361 , A61N1/36132 , A61N1/36167 , A61N1/36171 , A61N1/36178 , A61N1/37235 , A61N1/37247 , G06F19/00 , G09B23/28 , H04R25/75
Abstract: A method of treating tinnitus comprising measuring a patient's hearing, determining the patient's hearing loss and the patient's tinnitus frequency using the measurements of the patient's hearing, programming a clinical controller with the measurements of the patient's hearing, selecting a plurality of therapeutic tones, where the therapeutic tones are selected to be at least a half-octave above or below of the patient's tinnitus frequency, setting an appropriate volume for each of the plurality of tones, repetitively playing each of the plurality of therapeutic tones, and pairing a vagus nerve stimulation pulse train with each playing of a therapeutic tone, thereby reducing the patient's perception of tinnitus.
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公开(公告)号：US09265660B2
公开(公告)日：2016-02-23
申请号：US13934893
申请日：2013-07-03
Inventor： Michael P. Kilgard , Navzer Engineer , David Michael Pierce
CPC classification number: A61F11/00 , A61B5/128 , A61N1/0551 , A61N1/36036 , A61N1/36053 , A61N1/36092 , A61N1/361 , A61N1/36132 , A61N1/36167 , A61N1/36171 , A61N1/36178 , A61N1/37235 , A61N1/37247 , G06F19/00 , G09B23/28 , H04R25/75
Abstract: A method of treating tinnitus comprising measuring a patient's hearing, determining the patient's hearing loss and the patient's tinnitus frequency using the measurements of the patient's hearing, programming a clinical controller with the measurements of the patient's hearing, selecting a plurality of therapeutic tones, where the therapeutic tones are selected to be at least a half-octave above or below of the patient's tinnitus frequency, setting an appropriate volume for each of the plurality of tones, repetitively playing each of the plurality of therapeutic tones, and pairing a vagus nerve stimulation pulse train with each playing of a therapeutic tone, thereby reducing the patient's perception of tinnitus.
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公开(公告)号：US09522085B2
公开(公告)日：2016-12-20
申请号：US14527316
申请日：2014-10-29
Inventor： Michael P. Kilgard , Navzer Engineer , David Michael Pierce
CPC classification number: A61F11/00 , A61B5/128 , A61N1/0551 , A61N1/36036 , A61N1/36053 , A61N1/36092 , A61N1/361 , A61N1/36132 , A61N1/36167 , A61N1/36171 , A61N1/36178 , A61N1/37235 , A61N1/37247 , G06F19/00 , G09B23/28 , H04R25/75
Abstract: A method of treating tinnitus comprising measuring a patient's hearing, determining the patient's hearing loss and the patient's tinnitus frequency using the measurements of the patient's hearing, programming a clinical controller with the measurements of the patient's hearing, selecting a plurality of therapeutic tones, where the therapeutic tones are selected to be at least a half-octave above or below of the patient's tinnitus frequency, setting an appropriate volume for each of the plurality of tones, repetitively playing each of the plurality of therapeutic tones, and pairing a vagus nerve stimulation pulse train with each playing of a therapeutic tone, thereby reducing the patient's perception of tinnitus.
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10.发明授权公开(公告)号：US09474904B2
公开(公告)日：2016-10-25
申请号：US14538421
申请日：2014-11-11
Inventor： Michael P. Kilgard , Navzer Engineer , David Michael Pierce , Robert L. Rennaker
CPC classification number: A61N1/36067 , A61B5/1124 , A61N1/36003 , A61N1/36053 , A61N1/36092 , A61N1/361 , A61N1/36103 , A61N1/36132 , A61N1/36139 , A61N1/36178 , A61N1/37217 , A61N1/37235 , A61N1/37247 , A61N2/006 , A61N7/00 , A61N2007/0026 , G06F19/00 , G09B23/28
Abstract: A method of treating motor deficits in a stroke patient, comprising assessing a patient's motor deficits, determining therapeutic goals for the patient, based on the patient's motor deficits, selecting therapeutic tasks based on the therapeutic goals, performing each of the selected therapeutic tasks repetitively, observing the performance of the therapeutic tasks, initiating the stimulation of the vagus nerve manually at approximately a predetermined moment during the performance of the therapeutic tasks, stimulating the vagus nerve of the patient during the performance of the selected therapeutic tasks, and improving the patient's motor deficits.
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