公开(公告)号：US20070054119A1

公开(公告)日：2007-03-08

申请号：US11368263

申请日：2006-03-03

申请人： Piotr Garstecki ,  Douglas Weibel ,  Irina Gitlin ,  Shoji Takeuchi ,  Shengqing Xu ,  Zhihong Nie ,  Min Seo ,  Patrick Lewis ,  Eugenia Kumacheva ,  Howard Stone ,  George Whitesides

发明人： Piotr Garstecki ,  Douglas Weibel ,  Irina Gitlin ,  Shoji Takeuchi ,  Shengqing Xu ,  Zhihong Nie ,  Min Seo ,  Patrick Lewis ,  Eugenia Kumacheva ,  Howard Stone ,  George Whitesides

IPC分类号： B32B1/00

CPC分类号： B01J19/0093 ,  B01F3/0807 ,  B01F13/0062 ,  B01J19/06 ,  B01J2219/00873 ,  B22F1/0007 ,  B22F9/06 ,  Y10T428/2982

摘要： The present invention generally relates to systems and methods of forming particles and, in certain aspects, to systems and methods of forming particles that are substantially monodisperse. Microfluidic systems and techniques for forming such particles are provided, for instance, particles may be formed using gellation, solidification, and/or chemical reactions such as cross-linking, polymerization, and/or interfacial polymerization reactions. In one aspect, the present invention is directed to a plurality of particles having an average dimension of less than about 500 micrometers and a distribution of dimensions such that no more than about 5% of the particles have a dimension greater than about 10% of the average dimension, which can be made via microfluidic systems. In one set of embodiments, at least some of the particles may comprise a metal, and in certain embodiments, at least some of the particles may comprise a magnetizable material. In another set of embodiments, at least some of the particles may be porous. In some embodiments, the invention includes non-spherical particles. Non-spherical particles may be formed, for example, by urging a fluidic droplet into a channel having a smallest dimension that is smaller than the diameter of a perfect mathematical sphere having a volume of the droplet, and solidifying the droplet, and/or by exposing at least a portion of a plurality of particles to an agent able to remove at least a portion of the particles.

摘要翻译： 本发明一般涉及形成颗粒的系统和方法，并且在某些方面涉及形成基本上单分散的颗粒的体系和方法。 提供了用于形成这种颗粒的微流体系统和技术，例如，可以使用凝胶化，固化和/或化学反应如交联，聚合和/或界面聚合反应形成颗粒。 在一个方面，本发明涉及平均尺寸小于约500微米的多个颗粒和尺寸分布，使得不超过约5％的颗粒具有大于所述颗粒的约10％的尺寸 平均尺寸，可以通过微流体系统进行。 在一组实施方案中，至少一些颗粒可以包含金属，并且在某些实施方案中，至少一些颗粒可以包含可磁化材料。 在另一组实施方案中，至少一些颗粒可以是多孔的。 在一些实施方案中，本发明包括非球形颗粒。 非球形颗粒可以例如通过将流体液滴推入具有小于具有液滴体积的完美数学球体的直径的最小尺寸的通道，和/或通过 将多个颗粒的至少一部分暴露于能除去至少一部分颗粒的试剂。

公开(公告)号：US20050226932A1

公开(公告)日：2005-10-13

申请号：US11049266

申请日：2005-02-01

申请人： Hye-Jeong Yoon ,  Min Seo ,  Jeong-Kyung Kim

发明人： Hye-Jeong Yoon ,  Min Seo ,  Jeong-Kyung Kim

IPC分类号： A61K9/14 ,  A61K9/19 ,  A61K9/50 ,  A61K9/51 ,  A61K31/496 ,  A61K47/34

CPC分类号： A61K9/1075 ,  A61K9/0019 ,  A61K9/19 ,  A61K9/5153 ,  A61K31/496 ,  A61K47/34

摘要： The present invention relates to a pharmaceutical composition containing as an active ingredient, itraconazole. More particularly, the present invention relates to the pharmaceutical composition comprising itraconazole, a polylactic acid derivative, and an amphiphilic block copolymer. The polylactic acid derivative may be combined with a metal ion at the carboxylic acid terminal, and the amphiphilic block copolymer forms micelles or nano-particles in an aqueous medium.

摘要翻译： 本发明涉及含有伊曲康唑作为活性成分的药物组合物。 更具体地，本发明涉及包含伊曲康唑，聚乳酸衍生物和两亲性嵌段共聚物的药物组合物。 聚乳酸衍生物可以在羧酸末端与金属离子结合，两亲性嵌段共聚物在水性介质中形成胶束或纳米颗粒。

公开(公告)号：US20070131164A1

公开(公告)日：2007-06-14

申请号：US11354036

申请日：2006-02-15

申请人： Myung Park ,  Woon Kim ,  Min Seo

发明人： Myung Park ,  Woon Kim ,  Min Seo

IPC分类号： B05C3/00

CPC分类号： C23C18/1632 ,  H05K1/0393 ,  H05K3/187 ,  H05K3/241 ,  H05K3/381 ,  H05K3/389 ,  H05K2203/1545

摘要： Disclosed is an electroless metal film-plating system. While polyimide film is continuously fed from a roll, a series of wetting processes, including a degreasing process, an etching process, a neutralizing process, a coupling process, a catalyst-adding process, an undercoating process, and a plating process are conducted, in order, so as to plate one or both surfaces of the film with a conductive metal, followed by drying the conductive metal-plated film and taking up the plated film into a roll. A wetting process, in which the film passes through a liquid solution and is repetitively immersed in and drawn from a washing solution, is applied to all process parts, several parts notwithstanding, to produce a bilayer structure FCCL exhibiting superior physical properties such as peel strength. Also, after immersion in liquid in each process, the liquid is removed using wringing rollers so as to coat the material of interest at a uniform thickness. In the unwinding process for feeding the film, and the winding process for taking up the film, roller assemblies comprising a plurality of fixed rollers and a plurality of movable rollers are employed to control the tension of the film, thereby transporting the film without causing twisting or distortion. Also, one or more auxiliary operating processes are provided to facilitate the transfer of the film.

摘要翻译： 公开了一种无电金属膜电镀系统。 虽然聚酰亚胺膜从辊连续进料，但是进行了一系列润湿工艺，包括脱脂工艺，蚀刻工艺，中和过程，偶联工艺，催化剂添加工艺，底漆工艺和电镀工艺， 以便用导电金属对薄膜的一个或两个表面进行平板化，然后干燥导电金属镀膜，并将镀膜卷取成卷。 其中薄膜通过液体溶液并重复浸入洗涤溶液并从洗涤溶液中抽出的润湿方法被应用于所有加工部件，尽管如此，生产出具有优异物理性能如剥离强度的双层结构FCCL 。 此外，在每个工艺中浸入液体后，使用拧紧辊除去液体，以便以均匀的厚度涂覆目标材料。 在用于进给薄膜的退绕过程以及卷取卷取过程中，使用包括多个固定辊和多个可动辊的辊组件来控制薄膜的张力，从而输送薄膜而不引起扭曲 或失真。 此外，提供一个或多个辅助操作过程以便于胶片的转印。

公开(公告)号：US20050201972A1

公开(公告)日：2005-09-15

申请号：US10962204

申请日：2004-10-07

申请人： Min Seo ,  Bong Kim ,  In Choi ,  Myung Shim ,  Sa-Won Lee ,  Myung-Han Hyun ,  Jeong-Il Yu ,  Dong-Hoon Chang ,  Hye-Jeong Yoon ,  Jeong-Kyung Kim

发明人： Min Seo ,  Bong Kim ,  In Choi ,  Myung Shim ,  Sa-Won Lee ,  Myung-Han Hyun ,  Jeong-Il Yu ,  Dong-Hoon Chang ,  Hye-Jeong Yoon ,  Jeong-Kyung Kim

IPC分类号： A61K31/785 ,  C08L39/04

CPC分类号： A61K9/1075 ,  C08G63/08 ,  C08L53/00 ,  C08L2666/14 ,  C08L2666/02

摘要： The present invention relates to an amphiphilic block copolymer of a hydrophilic block and a hydrophobic block with a terminal hydroxyl group wherein the terminal hydroxyl group of the hydrophobic bock is substituted with a tocopherol or cholesterol group. It also relates to polymeric compositions capable of forming stable micelles in an aqueous solution, comprising the amphiphilic block copolymer and a polylactic acid derivative wherein one or more ends of the polylactic acid are covalently bound to at least one carboxyl group.

摘要翻译： 本发明涉及亲水嵌段和具有末端羟基的疏水嵌段的两亲嵌段共聚物，其中疏水基团的末端羟基被生育酚或胆固醇基团取代。 它还涉及能够在水溶液中形成稳定的胶束的聚合物组合物，其包含两亲嵌段共聚物和聚乳酸衍生物，其中聚乳酸的一个或多个末端与至少一个羧基共价结合。

公开(公告)号：US20070165295A1

公开(公告)日：2007-07-19

申请号：US11491961

申请日：2006-07-25

申请人： Dae-Sik Kim ,  Sae Jeoung ,  Joong Lee ,  Min Seo

发明人： Dae-Sik Kim ,  Sae Jeoung ,  Joong Lee ,  Min Seo

IPC分类号： G02F1/03

CPC分类号： G02B5/204 ,  G02B5/208 ,  G02B5/30

摘要： A filter having a high transmittance is disclosed. The filter comprises a substrate having a first surface and a second surface, and a periodic or random array of through-holes formed so as to pass through the first surface and the second surface. The through-hole has a size of subwavelength at a range of infrared and terahertz wave. Here, transmission resonance characteristic of incident light on the first surface is controlled by a shape of the through-hole.

摘要翻译： 公开了具有高透射率的滤光片。 滤光器包括具有第一表面和第二表面的基底，以及形成为穿过第一表面和第二表面的通孔的周期性或随机阵列。 通孔在红外线和太赫兹波的范围内具有亚波长的大小。 这里，通过通孔的形状来控制第一表面上的入射光的透射谐振特性。

公开(公告)号：US20060147744A1

公开(公告)日：2006-07-06

申请号：US11314584

申请日：2005-12-21

申请人： Min Seo ,  Woon Kim ,  Jae Kim

发明人： Min Seo ,  Woon Kim ,  Jae Kim

IPC分类号： B21D39/00 ,  B32B15/06 ,  B32B15/08 ,  C23C28/00 ,  C25D3/00

CPC分类号： C25D5/56 ,  C23C18/22 ,  C23C18/30 ,  C23C18/36 ,  C23C18/405 ,  C23C28/00 ,  H05K1/0346 ,  H05K3/181 ,  H05K3/381 ,  H05K2201/0154 ,  H05K2203/0789 ,  H05K2203/0793 ,  H05K2203/0796 ,  Y10T428/12556 ,  Y10T428/12562 ,  Y10T428/12569

摘要： Disclosed is a process for a conductive metal plated polyimide substrate. The process for a conductive metal plated polyimide substrate comprises a) etching surface of the polyimide film with KOH, mixed solution of ethylene glycol and KOH, or mixed solution of CrO3 and H2SO4, b) coupling the etched surface of the polyimide film with a coupling agent, c) absorbing a catalyst on the polyimide film, d) plating a first conductive metal on the polyimide film which the catalyst was absorbed without applying current, to form a first conductive metal thin film, and e) plating a second conductive metal on the first conductive metal thin film with applying current, to form a second conductive metal thin film.

摘要翻译： 公开了一种导电金属电镀聚酰亚胺基板的工艺。 导电金属电镀聚酰亚胺基板的方法包括：a）用KOH，乙二醇和KOH的混合溶液或CrO 3 3和H 2的混合溶液蚀刻聚酰亚胺膜的表面， b）将聚酰亚胺膜的蚀​​刻表面与偶联剂偶联，c）在聚酰亚胺膜上吸收催化剂，d）将第一导电金属镀在聚酰亚胺膜上， 在不施加电流的情况下吸收催化剂，形成第一导电金属薄膜，e）用施加电流在第一导电金属薄膜上镀覆第二导电金属，形成第二导电金属薄膜。

公开(公告)号：US20060081122A1

公开(公告)日：2006-04-20

申请号：US10530291

申请日：2003-10-31

申请人： Cheal Choi ,  Dal Kang ,  Chul Rho ,  Min Seo ,  Kee Kim ,  June Hur

发明人： Cheal Choi ,  Dal Kang ,  Chul Rho ,  Min Seo ,  Kee Kim ,  June Hur

IPC分类号： F16J1/10

CPC分类号： F16H21/20 ,  F04B49/126

摘要： Dual capacity compressor including a power generating part (20) having a reversible motor (21, 22) and a crank shaft (23) inserted in the motor (21, 23), a compression part (30) having a cylinder (32), a piston (31), and a connecting rod (33), a crank pin (110) in an upper part of the crank shaft (23) eccentric to an axis of the crank shaft, an eccentric sleeve (120) rotatably fitted to the crank pin (110), and the connecting rod (33) respectively, a key member (130) for positive fastening of the eccentric sleeve (120 ) to the crank pin (110) in all rotation directions of the motor, and an eccentric mass (200) provided to the eccentric sleeve (120) for rotating the eccentric sleeve (120) around the crank pin (110), thereby preventing relative motion between components that sustain the eccentricity, and permitting a smooth motion between the components.