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    Cardiac output measurement with metabolizable analyte containing fluid
    3.
    发明授权
    Cardiac output measurement with metabolizable analyte containing fluid 失效
    心脏输出测量与可代谢分析物含液体

    公开(公告)号：US5928155A

    公开(公告)日：1999-07-27

    申请号：US40167

    申请日：1998-03-17

    申请人： Philip E. Eggers ,  Scott P. Huntley ,  Gamal Eddin Khalil

    发明人： Philip E. Eggers ,  Scott P. Huntley ,  Gamal Eddin Khalil

    IPC分类号： A61B5/0215 ,  A61B5/00 ,  A61B5/0275 ,  A61B5/028 ,  A61B5/029 ,  A61B5/145 ,  A61M25/00

    CPC分类号： A61B5/14539 ,  A61B5/0215 ,  A61B5/0275 ,  A61B5/029 ,  A61B5/14542 ,  A61B5/1459 ,  A61B5/412 ,  A61B5/6853 ,  A61B5/028 ,  A61B5/1473 ,  A61M2025/0002 ,  A61M2025/0003

    摘要： Cardiac output is measured utilizing a catheter in conjunction with the indicator dilution technique. Non-thermal analyte-containing fluid is used as the injectate. This fluid is biocompatible with and metabolizable within the body of the patient. An analyte concentration sensor is mounted upon the catheter and located downstream within the bloodstream from the port from which the analyte-containing fluid is expressed. Because of the matching of rapid concentration sensor response with an analyte-containing fluid which is metabolizable, the measurement of cardiac output may be carried out as often as about one to three minutes in conjunction with an infusion interval substantially less than the measurement frequency interval. The analyte-containing fluids are selected from a group consisting of ammoniacal fluid, heparin, ethanol, a carbon dioxide releasing fluid, glucose, and anesthesia agent. The system performs in conjunction with a microprocessor-driven controller which automates the measurement procedure and provides a display of cardiac output and various cardiovascular parameters.

    摘要翻译： 结合指标稀释技术，使用导管测量心输出量。 不含热分析物的流体用作注射剂。 该液体与患者体内生物相容并可代谢。 分析物浓度传感器安装在导管上并位于从含有分析物的流体表达的端口的血流内的下游。 由于快速浓度传感器响应与可代谢的含分析物的流体的匹配，心输出量的测量可以与基本上小于测量频率间隔的输注间隔一起进行大约一到三分钟。 含分析物的流体选自氨流体，肝素，乙醇，释放二氧化碳的液体，葡萄糖和麻醉剂。 该系统与微处理器驱动的控制器一起执行，该控制器使测量程序自动化并提供心输出量和各种心血管参数的显示。

    Monitoring of total ammoniacal concentration in blood
    4.
    发明授权
    Monitoring of total ammoniacal concentration in blood 失效
    监测血液中总氨浓度

    公开(公告)号：US06219567B1

    公开(公告)日：2001-04-17

    申请号：US09337382

    申请日：1999-06-21

    申请人： Philip E. Eggers ,  Andrew R. Eggers ,  Eric A. Eggers ,  Scott P. Huntley

    发明人： Philip E. Eggers ,  Andrew R. Eggers ,  Eric A. Eggers ,  Scott P. Huntley

    IPC分类号： A61B500

    CPC分类号： A61B5/14542 ,  A61B5/14539 ,  A61B5/1473 ,  A61B5/412 ,  G01N33/84

    摘要： Total ammoniacal concentration (TAC) in blood is measured and displayed on a repetitive basis by a controller driven sensor arrangement which may be utilized either with a catheter structure or with a bypass system. The catheter based sensors may be employed with a peripheral region of the vascular system of the body. Repetitive measurements are carried out and these measurements are subjected to a moving average filtering procedure, whereupon the filtered TAC values are displayed numerically and graphically. The controller functions to compute the rate-of-rise of TAC and compares that value with a threshold rate-of-rise valuation which is inputted by the practitioner. Threshold values for TAC also may be inputted and the system not only provides alarm warnings for threshold excursions in TAC above threshold or excursions in rate-of-rise of TAC above threshold but also provides a visual cuing as a warning that TAC is elevating from one filtered measurement to the next.

    摘要翻译： 通过控制器驱动的传感器装置测量和显示血液中的总氨基酸浓度（TAC），其可以重复地显示，其可以与导管结构或旁路系统一起使用。 基于导管的传感器可以与身体的血管系统的周边区域一起使用。 进行重复测量，并对这些测量进行移动平均滤波过程，然后以数字和图形方式显示经过滤的TAC值。 控制器用于计算TAC的升率，并将该值与从业者输入的阈值上升率估值进行比较。 TAC的阈值也可以被输入，并且系统不仅提供TAC中阈值偏差的警报警报，或者超过阈值的TAC的上升速率的偏移量，还提供视觉检测作为TAC从一个升高的警告 过滤测量到下一个。

    METHOD, APPARATUS AND SYSTEM FOR COMPLETE EXAMINATION OF TISSUE WITH HAND-HELD IMAGING DEVICES
    5.
    发明申请
    METHOD, APPARATUS AND SYSTEM FOR COMPLETE EXAMINATION OF TISSUE WITH HAND-HELD IMAGING DEVICES 审中-公开
    用手持式成像装置完整检查组织的方法，装置和系统

    公开(公告)号：US20130225986A1

    公开(公告)日：2013-08-29

    申请号：US13854800

    申请日：2013-04-01

    申请人： Philip E. Eggers ,  Scott P. Huntley ,  Eric A. Eggers ,  Bruce A. Robinson

    发明人： Philip E. Eggers ,  Scott P. Huntley ,  Eric A. Eggers ,  Bruce A. Robinson

    IPC分类号： A61B5/00

    CPC分类号： A61B5/0033 ,  A61B8/0825 ,  A61B8/14 ,  A61B8/4245 ,  A61B8/4254 ,  A61B8/4405 ,  A61B8/4444 ,  A61B8/463 ,  A61B8/466 ,  A61B8/483 ,  G01S7/5205 ,  G01S15/8936

    摘要： A scan completeness auditing system for screening a volume of tissue comprising a manual image scanning device having an imaging probe, a position tracking system configured to track and record the position of the imaging probe during use, and a controller in communication with the recording system and the manual image scanning device, the controller configured to electronically receive and record the scanned images from the manual image scanning device, and to measure an image-to-image spacing and a scan-to-scan spacing between the scanned images within scan sequence and between scan sequences respectively. The scan completeness auditing system is further adapted to provide an alert to the operator if the image-to-image or scan-to-scan spacing exceeds an acceptable value.

    摘要翻译： 一种用于筛选组织体积的扫描完整性审查系统，包括具有成像探针的手动图像扫描装置，配置成在使用期间跟踪和记录成像探针的位置的位置跟踪系统，以及与记录系统通信的控制器， 所述手动图像扫描装置，所述控制器被配置为从所述手动图像扫描装置电子地接收和记录扫描的图像，并且测量扫描序列内的扫描图像之间的图像间图像间隔和扫描到扫描间隔，以及 在扫描序列之间。 扫描完整性审计系统还适用于向图像提供警告，如果图像到图像或扫描间距超过可接受的值。

    Apparatus Detection of Circulatory Anomalies
    6.
    发明申请
    Apparatus Detection of Circulatory Anomalies 审中-公开
    循环异常的装置检测

    公开(公告)号：US20140276034A1

    公开(公告)日：2014-09-18

    申请号：US13835697

    申请日：2013-03-15

    申请人： Philip E. Eggers ,  Andrew R. Eggers ,  Eric A. Eggers

    发明人： Philip E. Eggers ,  Andrew R. Eggers ,  Eric A. Eggers

    IPC分类号： A61B5/0275 ,  A61B5/00

    CPC分类号： A61B5/0275 ,  A61B5/0071 ,  A61B5/08 ,  A61B5/6815

    摘要： A system, and apparatus for detecting and quantifying circulatory anomalies, including right-to-left cardiac shunts. The apparatus implements a sensor system useful in connection with a circulatory indicator delivery system. The sensor apparatus is preferably configured with a series of emitter/detector pairs to optimize the sensitivity of detection of the circulating indicator. Sensing of the indicator concentration takes place at an arterial vasculature, for example, the pinna of the human ear. A monitor/controller calculates and displays a indicator/dye dilution curve to assess for the presence of a cardiac shunt. The monitor/controller further corrects the indicator/dilution curve displayed for any recirculation phenomena and can quantify any right-to-left shunt calculated conductance associated with detected shunts.

    摘要翻译： 一种用于检测和定量循环异常的系统和装置，包括从右到左的心脏分流。 该装置实现了与循环指示器传送系统有关的传感器系统。 传感器装置优选地配置有一系列发射器/检测器对，以优化循环指示器的检测灵敏度。 指示剂浓度的检测发生在动脉脉管系统，例如人耳的耳廓。 监视器/控制器计算并显示指示剂/染料稀释曲线以评估心脏分流的存在。 显示器/控制器进一步校正任何再循环现象显示的指示器/稀释曲线，并且可以量化与检测到的分流相关的任何从右到左的分流计算的电导。

    Hemostatic surgical blade, system and method of blade manufacture
    7.
    发明授权
    Hemostatic surgical blade, system and method of blade manufacture 有权
    止血手术刀片，系统和刀片制造方法

    公开(公告)号：US08142425B2

    公开(公告)日：2012-03-27

    申请号：US11980310

    申请日：2007-10-30

    申请人： Philip E. Eggers

    发明人： Philip E. Eggers

    IPC分类号： A61B18/04 ,  A61B17/32

    CPC分类号： A61B17/3211 ,  A61B18/082 ,  A61B2017/00526

    摘要： A hemostatic surgical blade is described which is formed of five symmetrically disposed layers. A martensitic stainless steel core is provided with oppositely disposed faces which are bonded to hard pure copper thermal transfer layers which, in turn, are supported by buttressing layers of austenitic stainless steel. The blade is heated by a blade heater circuit which is provided as a flexible circuit carrying one or more resistor heaters and associated leads supported by a polyimide substrate. A thermally conductive and electrically insulative adhesive is used to bond the flexible circuit to a blade blank. The system employs a multi-lead cable which is removable from an instrument handle. One blade embodiment involves an elongate stem for accessing body cavities and another embodiment incorporates a controller function within an instrument handle.

    摘要翻译： 描述了由五个对称设置的层形成的止血手术刀片。 马氏体不锈钢芯具有相对设置的面，其与硬纯铜热转印层接合，所述硬转移层又由奥氏体不锈钢的支撑层支承。 刀片由刀片加热器电路加热，叶片加热器电路被设置为作为柔性电路，其承载一个或多个电阻加热器和由聚酰亚胺基底支撑的相关引线。 使用导热和电绝缘粘合剂将柔性电路连接到刀片坯料。 该系统采用可从仪器手柄移除的多引线电缆。 一个刀片实施例涉及用于进入体腔的细长杆，另一个实施例在仪器手柄内并入控制器功能。

    System, method and apparatus for evaluating tissue temperature
    8.
    发明授权
    System, method and apparatus for evaluating tissue temperature 失效
    用于评估组织温度的系统，方法和装置

    公开(公告)号：US07684871B2

    公开(公告)日：2010-03-23

    申请号：US11241059

    申请日：2005-09-30

    申请人： Philip E. Eggers ,  John L. Ridihalgh ,  Mark Mayerchak ,  Gary Altman

    发明人： Philip E. Eggers ,  John L. Ridihalgh ,  Mark Mayerchak ,  Gary Altman

    IPC分类号： A61F2/00

    CPC分类号： G01K7/38 ,  A61B18/04 ,  A61B18/18 ,  A61B2017/00084 ,  A61F2/82 ,  A61F7/12 ,  A61F2250/0001

    摘要： Method, system and apparatus for monitoring target tissue temperatures wherein temperature sensors are configured as passive resonant circuits each with a unique resonating signature at monitoring temperatures extending below a select temperature setpoint. The resonant circuits are configured with an inductor component formed of windings about a ferrite core having a Curie temperature characteristic corresponding with a desired temperature setpoint. By selecting inductor winding turns and capacitance values, unique resonant center frequencies are detectable. Temperature monitoring can be carried out with implants at lower threshold and upper limit temperature responses. Additionally, the lower threshold sensors may be combined with auto-regulated heater implants having Curie transitions at upper temperature limits.

    摘要翻译： 用于监测目标组织温度的方法，系统和装置，其中温度传感器被配置为无源谐振电路，每个无源谐振电路在监测温度延伸到选定温度设定点以下时具有独特的谐振特征。 谐振电路由具有对应于期望温度设定点的居里温度特性的铁氧体磁芯绕组构成的电感器部件构成。 通过选择电感绕组匝数和电容值，可以检测到独特的谐振中心频率。 温度监测可以用较低阈值和上限温度响应的植入物进行。 此外，较低阈值传感器可与在较高温度极限下具有居里转变的自动调节加热器植入物组合。

    Accurate Cutting About and Into Tissue Volumes with Electrosurgically Deployed Electrodes
    10.
    发明申请
    Accurate Cutting About and Into Tissue Volumes with Electrosurgically Deployed Electrodes 审中-公开
    用电外科部署的电极准确切割和组织组织体积

    公开(公告)号：US20090149852A1

    公开(公告)日：2009-06-11

    申请号：US12371740

    申请日：2009-02-16

    申请人： Philip E. Eggers ,  Eric A. Eggers ,  Andrew R. Eggers

    发明人： Philip E. Eggers ,  Eric A. Eggers ,  Andrew R. Eggers

    IPC分类号： A61B18/18

    CPC分类号： A61B18/1492 ,  A61B2017/00973 ,  A61B2018/00011 ,  A61B2018/00214 ,  A61B2018/1286 ,  A61B2018/1475 ,  A61B2218/002

    摘要： Method, system and apparatus for carrying out accurate electrosurgical cutting. A thin resilient electrode is utilized at the forward end region of an instrument that is deployable from a longitudinally disposed slot positioned rearwardly of the tip of the instrument. Lateral sides of the slot extend between a forward location adjacent the tip and a rearward location. The electrode is deployed by urging it forwardly in compression to form an arch profile supported by the abutting slot sides adjacent the forward and rearward locations. Electrosurgically excitable with a cutting output, the electrode may carry out a cutting action both during its deployment and retraction into the noted slot. This permits a pivoting maneuver effective for circumscribing a volume of targeted tissue.

    摘要翻译： 用于进行精确电切割的方法，系统和装置。 在仪器的前端区域使用薄的弹性电极，其可从位于仪器尖端的纵向设置的狭槽展开。 狭槽的侧面在邻近尖端的前部位置和向后位置之间延伸。 电极通过向前推动而被压缩形成拱形轮廓，该拱形轮廓由邻近的前后方向的邻接槽侧支撑。 电切割可以切割输出，电极可以在其展开和退回到所述插槽期间执行切割动作。 这允许枢转机动有效地限制一定体积的目标组织。