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公开(公告)号：US4884221A
公开(公告)日：1989-11-28
申请号：US038366
申请日：1987-04-14
申请人： Masami Sugiyama , Nobuyuki Kita , Yoshihiro Tasaka
发明人： Masami Sugiyama , Nobuyuki Kita , Yoshihiro Tasaka
CPC分类号： G01J3/46 , G01J3/462 , G01J3/465 , G01J3/524 , G01J2001/444 , G01J2003/466 , G01J3/513 , G01N2201/12753
摘要： A color measuring apparatus including a photoelectric conversion device for outputting basic color signals corresponding to quantities of light of basic color components of a sample, respectively, a calculating device for calculating a color value of the sample in a predetermined colorimetric system, a target setting device for setting a target color value of the sample in the predetermined colorimetric system, a region setting device for setting a predetermined region containing the target color value, a region decision device for deciding whether or not the color value falls within the predetermined region, an approximation decision device for deciding whether or not the color value has most approximated to the target color value and an output device for outputting a result of the decision of the approximation decision device.
摘要翻译： 一种颜色测量装置，包括：光电转换装置，用于分别输出与样品的基本颜色分量的光量对应的基本色信号;计算装置，用于计算预定比色系统中的样品的颜色值;目标设定装置 用于设定所述预定比色系统中的样本的目标色值;区域设定装置，用于设定包含所述目标色彩值的预定区域;区域判定装置，用于判定所述色彩值是否落在所述预定区域内;近似值 判定装置，用于判定颜色值是否最接近于目标色彩值，以及输出装置，用于输出近似判定装置的判定结果。
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公开(公告)号：US4773761A
公开(公告)日：1988-09-27
申请号：US942446
申请日：1986-12-16
申请人： Masami Sugiyama , Yoshihiro Tasaka
发明人： Masami Sugiyama , Yoshihiro Tasaka
摘要： A photoelectric colorimeter which comprises a photoelectric conversion section including an optical filter to analyze light coming from a test piece and a reference calibrating sample into primary color elements, and a photosensor to convert each of said primary color elements into an electric signal; and a data processing section including a calibration constant calculating device for calculating a calibration constant for each of a plurality of reference calibrating samples on the basis of a calibration point of each of the reference calibrating samples and an information inputted from said photoelectric conversion section, a chromaticity point calculation device for calculating a chromaticity point of the test piece and that of each reference calibrating sample, a memory device for memorizing the calibration constant and calibration point of each of the reference calibrating samples, a device for estimating a new calibration constant suitable for the chromaticity point of the test piece between the respective calibration constants of the reference calibrating samples through the interpolation using a positional relation between the chromaticity point of the calibration point and that of the test piece as a parameter, and a correction device for correcting measured value of the test piece by the new calibration constant.
摘要翻译： 一种光电比色计，包括光电转换部分，该光电转换部分包括滤光器，用于分析来自测试片的光和参考校准样品为原色元素;以及光电传感器，用于将每个所述原色元件转换成电信号; 以及数据处理部，包括校准常数计算装置，用于根据每个参考校准样本的校准点和从所述光电转换部输入的信息计算多个参考校准样本中的每一个的校准常数， 用于计算测试片的色度点和每个参考校准样品的色度点的色度点计算装置，用于存储每个参考校准样品的校准常数和校准点的存储器件，用于估计适合于 通过使用校准点的色度点和测试片的色度点之间的位置关系作为参数，将参考校准样品的各个校准常数之间的测试片的色度点与用于校正测量值的校正装置 的 通过新的校准常数。
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公开(公告)号：US07803638B2
公开(公告)日：2010-09-28
申请号：US11379617
申请日：2006-04-21
申请人： Masami Sugiyama
发明人： Masami Sugiyama
IPC分类号： G01N33/533 , G01N33/53 , G01N21/76
CPC分类号： G01N33/582 , Y10S436/80 , Y10T436/17 , Y10T436/18
摘要： The present invention relates to a fluorescent label characterized by containing a hydrophilic polymer having an anionic group, a polyether derivative, and a phosphor, in which the phosphor is bound to the hydrophilic polymer via the polyether derivative, and also relates to a fluorescently labeled recognition substance labeled with the fluorescent label, and an immunoassay method using the recognition substance.
摘要翻译： 本发明涉及一种荧光标记，其特征在于含有具有阴离子基团的亲水性聚合物，聚醚衍生物和荧光体，其中荧光体通过聚醚衍生物与亲水性聚合物结合，并且还涉及荧光标记的识别 用荧光标记标记的物质和使用识别物质的免疫测定法。
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公开(公告)号：US20060240479A1
公开(公告)日：2006-10-26
申请号：US11379617
申请日：2006-04-21
申请人： Masami Sugiyama
发明人： Masami Sugiyama
CPC分类号： G01N33/582 , Y10S436/80 , Y10T436/17 , Y10T436/18
摘要： The present invention relates to a fluorescent label characterized by containing a hydrophilic polymer having an anionic group, a polyether derivative, and a phosphor, in which the phosphor is bound to the hydrophilic polymer via the polyether derivative, and also relates to a fluorescently labeled recognition substance labeled with the fluorescent label, and an immunoassay method using the recognition substance.
摘要翻译： 本发明涉及一种荧光标记，其特征在于含有具有阴离子基团的亲水性聚合物，聚醚衍生物和荧光体，其中荧光体通过聚醚衍生物与亲水性聚合物结合，并且还涉及荧光标记的识别 用荧光标记标记的物质和使用识别物质的免疫测定法。
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5.发明授权Color developing method, enzyme immunoassay using the color developing method, and immunochromatography incorporating the enzyme immunoassay 有权彩色显影法，使用彩色显影法的酶免疫测定法和含有酶免疫测定法的免疫层析法公开(公告)号：US06251618B1
公开(公告)日：2001-06-26
申请号：US09417220
申请日：1999-10-13
IPC分类号： G01N33543
CPC分类号： G01N33/581 , Y10S435/962
摘要： Disclosed are a color developing method utilizing the reaction of an indolyl derivative with an enzyme in the presence of a specific free radical compound and/or a specific chelate compound, and an enzyme immunoassay using the color developing method.
摘要翻译： 公开了利用吲哚基衍生物与酶在特定自由基化合物和/或特定螯合物的存在下的反应的彩色显影方法，以及使用彩色显影法的酶免疫测定法。
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公开(公告)号：US5432609A
公开(公告)日：1995-07-11
申请号：US177843
申请日：1994-01-05
申请人： Masami Sugiyama , Takao Sakai
发明人： Masami Sugiyama , Takao Sakai
摘要： A two-dimensional colorimeter focuses light through a beam splitter onto a rotary filter so that a first light receiving element can receive light from multiple points on a sample. A rotating filter can provide multiple measurements based upon different wavelengths of light. A portion of the light from the beam splitter also contacts a spectral sensor which separates the light from a particular point into primary wavelength elements which are converted into electrical signals. Based upon these primary wavelength elements, the first signals from the light receiving element are corrected. As a result, the measurement of chromaticity of multiple points on a sample can be performed accurately using a device of simple construction.
摘要翻译： 二维色度计将光束通过分束器聚焦到旋转滤光器上，使得第一光接收元件可以接收来自样品上多个点的光。 旋转滤波器可以基于不同波长的光提供多个测量。 来自分束器的光的一部分还接触光谱传感器，光谱传感器将光从特定点分离成主要波长元件，其被转换成电信号。 基于这些主波长元件，来自光接收元件的第一信号被校正。 结果，可以使用简单结构的装置来精确地进行样品上多个点的色度测量。
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公开(公告)号：US4419445A
公开(公告)日：1983-12-06
申请号：US360723
申请日：1982-03-22
CPC分类号： C12Q1/46 , C12Q2334/00
摘要： A method for determining the activity of cholinesterase comprising the steps of:mixing a solution containing p-methoxybenzoate demethylmonooxygenase, nicotinamide adenine dinucleotide reduced form (NADH) and p-methoxybenzoyl choline cation having the following formula: ##STR1## with a liquid containing cholinesterase, measuring the decrease in absorbance of light by NADH, which is based on a consumption of NADH, and calculating the activity of cholinesterase therefrom.
摘要翻译： 一种确定胆碱酯酶活性的方法，包括以下步骤：将含有对甲氧基苯甲酸甲酯脱甲基单加氧酶，烟酰胺腺嘌呤二核苷酸还原形式（NADH）和具有下式的对甲氧基苯甲酰胆碱阳离子的溶液与含有胆碱酯酶的液体混合， 测量基于NADH消耗的NADH对光的吸光度的降低，并计算其中胆碱酯酶的活性。
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公开(公告)号：US4205918A
公开(公告)日：1980-06-03
申请号：US881177
申请日：1978-02-27
申请人： Tohru Kisanuki , Masami Sugiyama , Takeshi Kosaka
发明人： Tohru Kisanuki , Masami Sugiyama , Takeshi Kosaka
摘要： A hand-carriable, compact color meter for indicating proper amount of adjustment of color compensation filters interposed in the light path of a color printer for the compensation of color balance of the light illuminating a film or the slide set on the printer. The color meter includes an indicating lamp, a photocell to be exposed to the light passing through the film or slide, a plurality of optical color filters selectively disposed in front of the photocell to provide the photocell with spectral sensitivities corresponding to the spectral sensitivity of the printing paper, a plurality of fixed or variable resistors selectable in correspondence to the selection of the color filter, and an electric circuit for actuating the indicating lamp in accordance with the relationship between the output of the light measuring circuit and a reference voltage commensurate with the selected one of the resistors. In a preferred embodiment, the color meter further includes a combination of a variable resistor and a filter for determination of exposure time.
摘要翻译： 一种手提式紧凑型色表，用于指示插入彩色打印机光路中的适当量的色彩补偿滤光片的调整，以补偿照亮胶片或设置在打印机上的幻灯片的光的色彩平衡。 色度计包括指示灯，要暴露于穿过膜或载玻片的光的光电池，选择性地设置在光电管前面的多个光学滤色器，以向光电池提供与光电池的光谱灵敏度相对应的光谱灵敏度 打印纸，对应于滤色器的选择可选择的多个固定或可变电阻器，以及用于根据光测量电路的输出与与该测量电路相当的参考电压之间的关系致动指示灯的电路 选择一个电阻。 在优选实施例中，色度计还包括可变电阻器和用于确定曝光时间的滤光器的组合。
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公开(公告)号：US20090081696A1
公开(公告)日：2009-03-26
申请号：US12277359
申请日：2008-11-25
申请人： Masami Sugiyama
发明人： Masami Sugiyama
IPC分类号： G01N33/53 , C08F210/02 , C08F112/06 , C08F226/06
CPC分类号： G01N33/582 , C08F212/14 , C08F212/36 , C08F220/06 , C08F226/06 , C09K11/06 , C09K11/07 , C09K2211/1007 , C09K2211/1088 , G01N21/76 , G01N33/52 , G01N33/532 , G01N2333/916
摘要： An object of the present invention is to provide a luminescence enhancer by which a luminescence such as chemiluminescence can be enhanced with higher sensitivity and the luminescence can be continued over a prolonged period of time. That is, the present invention provides a luminescence enhancer containing a heteropolymer as an active ingredient, a method for measuring the luminescence using a luminescent substrate and said luminescence enhancer, and a method for analyzing a substance to be measured in a specimen wherein the specimen, an antigen and/or antibody corresponding to a substance to be measured, an antigen and/or antibody labeled-form with an activator and a luminescent substrate are reacted in the presence of said luminescence enhancer to measure the luminescence.
摘要翻译： 本发明的目的是提供一种发光增强剂，通过该发光增强剂可以以更高的灵敏度增强诸如化学发光的发光，并且可以在长时间内持续发光。 也就是说，本发明提供含有异源聚合物作为有效成分的发光增强剂，使用发光底物和所述发光增强剂测定发光的方法，以及在试样中分析待测物质的方法， 与待测物质相对应的抗原和/或抗体，用激活剂和发光底物标记形式的抗原和/或抗体在所述发光增强剂存在下反应以测量发光。
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10.发明授权Color developing method, enzyme immunoassay using the color developing method, and immunochromatography incorporating the enzyme immunoassay 失效彩色显影法，使用彩色显影法的酶免疫测定法和含有酶免疫测定法的免疫层析法
公开(公告)号：US5998156A
公开(公告)日：1999-12-07
申请号：US104166
申请日：1998-06-25
IPC分类号： G01N33/58 , G01N33/543 , G01N33/576
CPC分类号： G01N33/581 , Y10S435/962
摘要： Disclosed are a color developing method utilizing the reaction of an indolyl derivative with an enzyme in the presence of a specific free radical compound and/or a specific chelate compound, and an enzyme immunoassay using the color developing method.
摘要翻译： 公开了利用吲哚基衍生物与酶在特定自由基化合物和/或特定螯合物的存在下的反应的彩色显影方法，以及使用彩色显影法的酶免疫测定法。
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