公开(公告)号：US20050004214A1

公开(公告)日：2005-01-06

申请号：US10611025

申请日：2003-07-01

Applicant: Mark Dewis ,  Michelle Huber ,  Michael Cossette

Inventor： Mark Dewis ,  Michelle Huber ,  Michael Cossette

IPC: A23G3/00 ,  A23G3/34 ,  A23G3/36 ,  A23G3/50 ,  A23G4/00 ,  A23G4/06 ,  A23G4/18 ,  C07C69/34 ,  C07C69/44 ,  C07C233/05 ,  C07C233/06 ,  C07C233/18 ,  C07C67/26

CPC classification number: A23G3/36 ,  A23G3/346 ,  A23G3/50 ,  A23G4/06 ,  A23G4/18 ,  A23G2200/00 ,  A23G2220/00 ,  C07C69/34 ,  C07C69/44 ,  C07C233/05 ,  C07C233/06 ,  C07C233/18 ,  C07C2601/14

Abstract: Described is a genus of menthyl half acid ester derivatives having the structure: and processes for producing same, wherein n is an integer of from 1 to 5; wherein X is either —OR″ or —NRR′; wherein R″ is hydrogen, C1-C5 lower alkyl or C3-C6 lower alkenyl; wherein R is hydrogen, C1-C5 lower alkyl, 2-hydroxyethyl or cyclopropyl and wherein R′ is hydrogen, methyl or ethyl; with the proviso that when X is —OR″, n is an integer of from 3 to 5, having utility for augmenting, enhancing or imparting a taste or cooling effect or refreshing effect in or to an ingestible or topical composition.

Abstract translation: 描述了具有以下结构的薄荷酯半酸酯衍生物及其生产方法，其中n为1至5的整数; 其中X为-OR“或-NRR'; 其中R“为氢，C 1 -C 5低级烷基或C 3 -C 6低级烯基; 其中R是氢，C1-C5低级烷基，2-羟乙基或环丙基，其中R'是氢，甲基或乙基; 条件是当X为-OR“时，n为3至5的整数，其可用于增加，增强或赋予可食用或局部组合物中的味道或凉爽效果或清爽效果。

公开(公告)号：US20070225199A1

公开(公告)日：2007-09-27

申请号：US11419311

申请日：2006-06-16

Applicant: Mark Dewis ,  Michelle Huber ,  David Agyemang ,  Garry Conklin

Inventor： Mark Dewis ,  Michelle Huber ,  David Agyemang ,  Garry Conklin

IPC: A61Q13/00

CPC classification number: A23L2/56 ,  A23L27/2026 ,  A23L27/203 ,  A23L27/29

Abstract: Described is to a process for augmenting, enhancing, modifying or imparting a berry or citrus aroma or taste in or to a foodstuff or aqueous beverage comprising the step of adding to a foodstuff or aqueous beverage an aroma or taste augmenting, enhancing, modifying or imparting quantity and concentration of at least one oxo-terpene carbinol, carbinyl C1-C6 alkanoate or C4-C6 alkenoate.

Abstract translation: 描述了一种用于在食品或含水饮料中增加，增强，改良或赋予浆果或柑橘香气或味道的方法，其包括向食品或水性饮料中添加芳香或味道增强，增强，改性或赋予 至少一种氧代 - 萜烯甲醇的量和浓度，碳水化合物C 1 -C 6烷酸酯或C 4 -C 6烷基， /亚油酸酯。

公开(公告)号：US20050010062A1

公开(公告)日：2005-01-13

申请号：US10618367

申请日：2003-07-10

Applicant: Mark Dewis ,  Michelle Huber

Inventor： Mark Dewis ,  Michelle Huber

IPC: A23L1/226 ,  A61K8/36 ,  A61K8/37 ,  A61K8/42 ,  A61K8/49 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  C07C51/16 ,  C07C51/295 ,  C07C57/03 ,  C07C67/12 ,  C07C69/587 ,  C07C69/96 ,  C07C233/09 ,  C07C233/02 ,  C07D317/44

CPC classification number: A61K8/361 ,  A23L27/2026 ,  A23L27/2054 ,  A61K8/37 ,  A61K8/42 ,  A61K8/4973 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  C07C51/16 ,  C07C51/295 ,  C07C57/03 ,  C07C67/12 ,  C07C69/587 ,  C07C69/96 ,  C07C233/09

Abstract: Described is a genus of E2,E4,Z8-undecatrienoic acid derivatives defined according to the structure: wherein Z represents —OR″ or —NRR′ with the provisos that when Z is —OR″, R″ is hydrogen, C1-C6 straight chain or branched-chain alkyl or C3-C6 straight chain or branched-chain alkenyl; and when Z is —NRR′, R represents, in the alternative, hydrogen, methyl or ethyl and R′ represents methyl, ethyl, n-propyl, cyclopropyl, isopropyl, n-butyl, sec-butyl, isobutyl, 2-methylbutyl, cyclobutyl, cyclopentyl or allyl. The E2,E4,Z8-undecatrienoic acid derivatives are useful in imparting, augmenting and/or enhancing flavors, aromas and somatosensory effects in or to consumable materials such as foods, beverages, skin care products, oral care products, medicinal products and the like. Also described is a synthesis process for producing such derivatives.

Abstract translation: 描述了根据以下结构定义的E2，E4，Z8-十一碳烯酸衍生物属：其中Z表示-OR“或-NRR'，条件是当Z为-OR”时，R“为氢，C1 -C6直链或支链烷基或C3-C6直链或支链烯基; 当Z是-NRR'时，R代表氢，甲基或乙基，R'代表甲基，乙基，正丙基，环丙基，异丙基，正丁基，仲丁基，异丁基，2-甲基丁基， 环丁基，环戊基或烯丙基。 E2，E4，Z8-十一碳三烯酸衍生物可用于赋予，增强和/或增强食用，饮料，护肤品，口腔护理产品，药用产品等中的消耗材料中的香料，香气和体感效应 。 还描述了制备这种衍生物的合成方法。

公开(公告)号：US20050197387A1

公开(公告)日：2005-09-08

申请号：US10861751

申请日：2004-06-04

Applicant: Mark Dewis ,  Michelle Huber

Inventor： Mark Dewis ,  Michelle Huber

IPC: A23L1/226 ,  A61K8/36 ,  A61K8/37 ,  A61K8/42 ,  A61K8/49 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  C07C51/16 ,  C07C51/295 ,  C07C57/03 ,  C07C67/12 ,  C07C69/587 ,  C07C69/96 ,  C07C233/09 ,  A61K31/202 ,  A61K31/16 ,  A61K31/20

CPC classification number: A61K8/361 ,  A23L27/2026 ,  A23L27/2054 ,  A61K8/37 ,  A61K8/42 ,  A61K8/4973 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  C07C51/16 ,  C07C51/295 ,  C07C57/03 ,  C07C67/12 ,  C07C69/587 ,  C07C69/96 ,  C07C233/09

Abstract: Described is a genus of undecatrienoic acid derivatives useful in imparting, augmenting and/or enhancing flavors, aromas and somatosensory effects in or to consumable materials such as foods, beverages, skin care products, oral care products, medicinal products and the like. Also described is a synthesis process for producing such derivatives.

Abstract translation: 描述了一种十一碳三烯酸衍生物，其可用于赋予，增强和/或增强食用，饮料，护肤品，口腔护理产品，医药产品等消耗材料中的香料，香气和体感效应。 还描述了制备这种衍生物的合成方法。

公开(公告)号：US20050042257A1

公开(公告)日：2005-02-24

申请号：US10955833

申请日：2004-09-30

Applicant: Mark Dewis ,  David Edwards ,  Lesley Kendrick ,  Maria Wright ,  Amir Yusuf

Inventor： Mark Dewis ,  David Edwards ,  Lesley Kendrick ,  Maria Wright ,  Amir Yusuf

IPC: A23L27/00 ,  A23L27/20 ,  A23L27/29 ,  A61K47/00 ,  A23L2/00

CPC classification number: A23G3/36 ,  A23G3/48 ,  A23G4/06 ,  A23G4/068 ,  A23L27/2022 ,  A23L27/29 ,  C11B9/0011

Abstract: This invention pertains to a method for flavoring an ingestible composition with a flavoring agent in organoleptically purified form, unaccompanied by substances of natural origin present in mango. The flavoring agent may be used in a wide variety of ingestible vehicles such as chewing gum compositions, hard and soft confections, dairy products, beverage products including juice drinks and juice products, green vegetable and chicken products, and the like. The present invention also pertains to an ingestible composition comprising an ingestible vehicle and an organoleptically effective amount of the purified flavoring agent. The present invention further pertains to ethyl 3-mercaptobutyrate represented by the formula, CH3(SH)CHCH2COOCH2CH3, in purified form, unaccompanied by substances of natural origin present in mango. The present invention still further pertains to a method to confer, enhance, improve, or modify the odor properties of a perfuming composition or a perfumed article, which comprises adding to the perfuming composition or perfumed article, ethyl 3-mercaptobutyrate represented by the formula, CH3(SH)CHCH2COOCH2CH3. The present invention still further pertains to a perfuming composition or a perfumed article containing as an active perfuming ingredient, ethyl 3-mercaptobutyrate represented by the formula, CH3(SH)CHCH2COOCH2CH3. The present invention also pertains to a method for preparing ethyl 3-mercaptobutyrate which comprises reacting ethyl crotonate with sodium hydrogen sulfide and sodium bicarbonate to form the disulfide dimer of ethyl 3-mercaptobutyrate followed by reducing the disulfide dimer to yield ethyl 3-mercaptobutyrate.

Abstract translation: 本发明涉及一种通过感官纯化形式调味具有调味剂的可摄入组合物的方法，不伴随芒果中存在的天然来源的物质。 调味剂可以用于各种可摄取的载体，例如口香糖组合物，硬和软糖果，乳制品，饮料产品，包括果汁饮料和果汁产品，绿色蔬菜和鸡肉制品等。 本发明还涉及包含可摄入载体和感官有效量的纯化调味剂的可摄取组合物。 本发明还涉及以通式CH3（SH）CHCH2COOCH2CH3表示的3-巯基丁酸乙酯，纯化形式，不含芒果中存在的天然来源的物质。 本发明还涉及赋予，增强，改善或改善加香组合物或加香制品的气味性质的方法，其包括向加香组合物或香料制品中加入由式表示的3-巯基丁酸乙酯， CH3（SH）CHCH2COOCH2CH3。 本发明还涉及含有作为活性加香成分的由式CH3（SH）CHCH2COOCH2CH3表示的3-巯基丁酸乙酯的加香组合物或香料制品。 本发明还涉及制备3-巯基丁酸乙酯的方法，该方法包括使巴豆酸乙酯与硫化氢钠和碳酸氢钠反应，形成3-巯基丁酸乙酯的二硫化物二聚物，然后还原二硫化物二聚物，得到3-巯基丁酸乙酯。

公开(公告)号：US20060057268A1

公开(公告)日：2006-03-16

申请号：US10939096

申请日：2004-09-10

Applicant: Mark Dewis ,  Garry Conklin ,  Tao Pei

Inventor： Mark Dewis ,  Garry Conklin ,  Tao Pei

IPC: A23L1/22

CPC classification number: C07C233/05 ,  A23L27/202 ,  A23L27/203 ,  A23L27/204

Abstract: Saturated and unsaturated compounds having sweet, salt or umami taste enhancement qualities. The compounds have the structure: where R1═H or methyl; R2 is selected from the group consisting of H, C1-C4 alkyl, alkenyl and methylene; R3 is selected from the group consisting of H, C1-C8 straight or branched chain alkyl, alkenyl, dienalkyl or phenyl; or if R1═H, R2 and R3 taken together can represent cyclopropyl, cyclobutyl, cyclopentyl, cyclopentenyl, cyclohexyl, or cyclohexenyl; R4 is selected from the group consisting of H, methyl and ethyl; R5 is selected from the group consisting of H, methyl and ethyl; R6 is selected from the group consisting of H, C1-C9 straight or branched chain alkyl, alkenyl, alkyldienyl, acyclic or containing no more than one ring; with the proviso that in structure 1 when R4 is H or Me; and R5═H or methyl, R6 may be selected from the group described above or phenyl.

Abstract translation: 饱和和不饱和化合物，具有甜味，盐或鲜味增强品质。 该化合物具有以下结构：

公开(公告)号：US20050074533A1

公开(公告)日：2005-04-07

申请号：US10678558

申请日：2003-10-03

Applicant: Thumplasseril John ,  Markus Eckert ,  Mark Dewis ,  Jan Colstee ,  Neil da Costa

Inventor： Thumplasseril John ,  Markus Eckert ,  Mark Dewis ,  Jan Colstee ,  Neil da Costa

IPC: A23G3/34 ,  A23G4/00 ,  A23G4/06 ,  A23L1/226 ,  A23L1/305 ,  A23L2/56 ,  A61K8/42 ,  A61Q11/00 ,  C07C233/09 ,  C07D295/185 ,  A23L1/22

CPC classification number: C07D295/185 ,  A01N65/08 ,  A23G3/346 ,  A23G4/06 ,  A23G4/068 ,  A23G2200/00 ,  A23G2200/14 ,  A23L2/56 ,  A23L3/3472 ,  A23L27/11 ,  A23L27/12 ,  A23L27/2028 ,  A23L27/2054 ,  A23L33/105 ,  A23L33/12 ,  A23L33/175 ,  A61K8/42 ,  A61K8/4913 ,  A61K8/4926 ,  A61K2800/242 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q13/00 ,  A61Q17/005 ,  A61Q19/00 ,  C07C233/09

Abstract: Described are mixtures of at least four of the alkadienamides defined according to the structure: wherein R represents C1-C2 n-alkyl; R1 is 2-methyl-1-propyl and R2 is hydrogen, or R1 and R2 taken together is a moiety having the formula —(CH2)n— wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

Abstract translation: 描述了根据以下结构定义的至少四种烷酰胺的混合物：其中R表示C 1 -C 2正烷基; R 1是2-甲基-1-丙基，R 2是氢，或者R 1和R 2一起是具有式 - （CH 2）n - 的部分，其中n是4或5，或包含基本浓度的这种混合物的组合物， 以新颖的方法：（a）提取一种Pi子种，Pi um n或琵琶鹦鹉之一的基本干燥的果实; （b）天然产物形成合成; 或（c）合成产物形成合成。 还描述了如此形成的产品用于在消耗材料和/或口腔和/或哺乳动物表皮中或/或在哺乳动物表皮上增加，增强或赋予芳香，味觉，化学疗效和/或抗菌作用的用途。

公开(公告)号：US20080008811A1

公开(公告)日：2008-01-10

申请号：US11857672

申请日：2007-09-19

Applicant: Thumplasseril John ,  Markus Eckert ,  Mark Dewis ,  Jan Colstee ,  Neil da Costa

Inventor： Thumplasseril John ,  Markus Eckert ,  Mark Dewis ,  Jan Colstee ,  Neil da Costa

IPC: A23L1/221

CPC classification number: C07D295/185 ,  A01N65/08 ,  A23G3/346 ,  A23G4/06 ,  A23G4/068 ,  A23G2200/00 ,  A23G2200/14 ,  A23L2/56 ,  A23L3/3472 ,  A23L27/11 ,  A23L27/12 ,  A23L27/2028 ,  A23L27/2054 ,  A23L33/105 ,  A23L33/12 ,  A23L33/175 ,  A61K8/42 ,  A61K8/4913 ,  A61K8/4926 ,  A61K2800/242 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q13/00 ,  A61Q17/005 ,  A61Q19/00 ,  C07C233/09

Abstract: Described are mixtures of at least four of the alkadienamides defined according to the structure: wherein R represents C1-C2 n-alkyl; R1 is 2-methyl-1-propyl and R2 is hydrogen, or R1 and R2 taken together is a moiety having the formula —(CH2)n—, wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

Abstract translation: 描述了根据以下结构定义的至少四种烷酰胺的混合物：其中R表示C 1 -C 2烷基; R 1是2-甲基-1-丙基，R 2是氢，或R 1和R 2是氢， 一起是具有下式的部分：其中n为4或5，或含有基本浓度的这种混合物的组合物，其按照新颖的方法制备 过程：（a）提取per皮种之一的干燥果实，Pi um或per per; （b）天然产物形成合成; 或（c）合成产物形成合成。 还描述了如此形成的产品用于在消耗材料和/或口腔和/或哺乳动物表皮中或/或在哺乳动物表皮上增强，增强或赋予芳香，味觉，化学疗效和/或抗菌作用的用途。

公开(公告)号：US20080008810A1

公开(公告)日：2008-01-10

申请号：US11857587

申请日：2007-09-19

Applicant: Thumplasseril John ,  Markus Eckert ,  Mark Dewis ,  Jan Colstee ,  Neil Costa

Inventor： Thumplasseril John ,  Markus Eckert ,  Mark Dewis ,  Jan Colstee ,  Neil Costa

IPC: A23L1/221

CPC classification number: C07D295/185 ,  A01N65/08 ,  A23G3/346 ,  A23G4/06 ,  A23G4/068 ,  A23G2200/00 ,  A23G2200/14 ,  A23L2/56 ,  A23L3/3472 ,  A23L27/11 ,  A23L27/12 ,  A23L27/2028 ,  A23L27/2054 ,  A23L33/105 ,  A23L33/12 ,  A23L33/175 ,  A61K8/42 ,  A61K8/4913 ,  A61K8/4926 ,  A61K2800/242 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q13/00 ,  A61Q17/005 ,  A61Q19/00 ,  C07C233/09

Abstract: Described are mixtures of at least four of the alkadienamides defined according to the structure: wherein R represents C1-C2 n-alkyl; R1 is 2-methyl-1-propyl and R2 is hydrogen, or R1 and R2 taken together is a moiety having the formula —(CH2)n—, wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

公开(公告)号：US20060154347A1

公开(公告)日：2006-07-13

申请号：US11031720

申请日：2005-01-07

Applicant: Kwang-Pil Choi ,  Michael McLean ,  John Buckley ,  Mark Dewis

Inventor： Kwang-Pil Choi ,  Michael McLean ,  John Buckley ,  Mark Dewis

IPC: C12P17/02 ,  C12P15/00

CPC classification number: C12P7/26 ,  C12P7/02

Abstract: The present invention is directed to the use of yeasts to produce spiroketal fragrance materials. The preferred yeasts used in the method of the invention are Bensingtonia ciliate and Cryptococcus laurentii.

Abstract translation: 本发明涉及酵母制造螺旋酮香料的用途。 在本发明的方法中使用的优选的酵母是Bensingtonia ciliate和月桂树隐球酵母。