公开(公告)号：US10570084B2

公开(公告)日：2020-02-25

申请号：US15802980

申请日：2017-11-03

Applicant: ExxonMobil Research and Engineering Company

Inventor： Stephen T. Cohn ,  Christopher M. Evans ,  Christine A. Costello ,  James R. Lattner

IPC: C07C67/08 ,  C07C69/76 ,  C08K5/00 ,  C07C69/616 ,  C08K5/12 ,  C07C67/12 ,  C07C69/753 ,  C07C67/303 ,  C08F14/06 ,  C08K5/09 ,  C08L75/04 ,  C08L23/08 ,  C08L27/06 ,  C08L33/10 ,  C07D307/92 ,  G01R33/46

Abstract: A diester of a fused ring compound of the formula (I): wherein: the fused rings are both aromatic; R1 and R4 to R6 substituents are H or ester moieties having C1 to C20 linear or branched alkyl chains; R2 and R3 are —C(O)OCxHy, wherein x is from 10 to 12 and y is from 21 to 25; two adjacent R1 to R4 substituents are —C(O)OCxHy, wherein x is from 10 to 12 and y is from 21 to 25; and when R3 and R4 are ester moieties, the alkyl chains of R4 are not C5 or C8; and polymer compositions containing the fused ring compound.

公开(公告)号：US20170275222A1

公开(公告)日：2017-09-28

申请号：US15506583

申请日：2015-08-25

Applicant: The Scripps Research Institute

Inventor： Roy A. PERIANA ,  Michael M. KONNICK ,  Brian G. HASHIGUCHI

IPC: C07C29/48 ,  C07C67/055 ,  C07C67/12 ,  C07C53/18

CPC classification number: C07C29/48 ,  C07C29/72 ,  C07C51/54 ,  C07C53/18 ,  C07C67/035 ,  C07C67/05 ,  C07C67/055 ,  C07C67/12 ,  C07C71/00 ,  C07C2523/08 ,  C07C2523/14 ,  C07C2523/16 ,  C07C2523/70 ,  Y02P20/582 ,  C07C69/63

Abstract: Provided are methods and materials for the functionalization of a heteroalkane or arene using an oxidizing electrophile as a stoichiometric agent or catalyst. The reaction involves the replacement of a hydrogen atom on an sp3-hybridized carbon atom of the heteroalkane or of a hydrogen atom on an sp2-hybridized carbon atom of the arene. A main group element organometallic intermediate is formed that undergoes further conversion to a functionalized heteroalkane or arene.

公开(公告)号：US5650158A

公开(公告)日：1997-07-22

申请号：US433483

申请日：1995-05-11

Applicant: Horst Eierdanz ,  Peter Busch ,  Holger Tesmann ,  Walter Knoerr ,  Rolf Wachter

Inventor： Horst Eierdanz ,  Peter Busch ,  Holger Tesmann ,  Walter Knoerr ,  Rolf Wachter

IPC: A61K8/00 ,  A61K8/37 ,  A61K8/39 ,  A61K31/25 ,  A61P17/00 ,  A61Q17/00 ,  A61Q19/00 ,  C07C67/12 ,  C07C69/34 ,  C07C69/347 ,  C07C69/40 ,  C07C69/593 ,  A61K7/48

CPC classification number: A61K8/39 ,  A61Q19/00 ,  C07C69/34 ,  C07C69/593 ,  Y10S514/844 ,  Y10S514/937 ,  Y10S514/938

Abstract: A skin-moisture-regulating composition for cosmetic or dermatological preparations, the composition containing succinic acid derivatives corresponding to formula I:R.sup.1 O(C.sub.n H.sub.2n O).sub.x CO--CHR.sup.2 --CHR.sup.3 --CO(OC.sub.n H.sub.2n O).sub.y OR.sup.4 (I)wherein R.sup.1 is an alkyl, alkenyl, mono-or dihydroxyalkyl or hydroxyalkenyl group containing 6 to 22 carbon atoms, one of R.sup.2 and R.sup.3 is hydrogen and the other is an alkyl or alkenyl group containing 12 to 22 carbon atoms, n=2 or 3, x and y are average degrees of alkoxylation and have values of 0 to 20 and 1 to 20, respectively, and R.sup.4 is hydrogen or a group R.sup.1 O--(C.sub.n H.sub.2n O).sub.x --CO--CHR.sup.2 --CHR.sup.3 --CO--, or an alkyl, alkenyl, mono- or dihydroxyalkyl or hydroxyalkenyl group containing 6 to 22 carbon atoms.

Abstract translation: PCT No.PCT / EP93 / 03044 Sec。 371日期1995年5月11日 102（e）日期1995年5月11日PCT 1993年11月2日PCT公布。 公开号WO94 / 11333 日本1994年5月26日用于化妆品或皮肤病学制剂的皮肤调湿组合物，含有对应于式I的琥珀酸衍生物的组合物：R1O（CnH2nO）xCO-CHR2-CHR3-CO（OCnH2nO）yOR4（I）其中R1是 烷基，烯基，含有6-22个碳原子的一或二羟基烷基或羟基烯基，R2和R3之一是氢，另一个是含有12-22个碳原子的烷基或烯基，n = 2或3，x和y 是平均烷氧基化度，分别为0至20和1至20，R4为氢或R1O-（CnH2nO）x-CO-CHR2-CHR3-CO-，或烷基，烯基， 或含有6-22个碳原子的二羟基烷基或羟基烯基。

公开(公告)号：US5501708A

公开(公告)日：1996-03-26

申请号：US129181

申请日：1993-10-07

Applicant: Peter Pojer ,  Kenneth C. Montgomery ,  Chi P. Huynh ,  Brian Milligan

Inventor： Peter Pojer ,  Kenneth C. Montgomery ,  Chi P. Huynh ,  Brian Milligan

IPC: C07C67/12 ,  C07C67/14 ,  C07C69/08 ,  C07C69/76 ,  C07C69/80 ,  C07C69/82 ,  C07C69/84 ,  C07D307/89 ,  C07H13/08 ,  C14C3/04 ,  C14C3/06 ,  C14C3/08

CPC classification number: C07H13/08 ,  C07C67/08 ,  C07C69/76 ,  C07C69/80 ,  C14C3/04

Abstract: An organic polyol ester of a polycarboxylic acid having formulae (Para) and/or (Meta) and/or (Ortho), wherein R.sub.6 is --(COOR.sub.1)x, or (I).sub.1 R.sub.7 is H; or R.sub.6 and R.sub.7 together for (II); R.sub.1 and R.sub.2 are hydrogen or --OR.sub.1 and --OR.sub.2 together form an anhydride (--0--) bond; x is an integer of 0 or 1; Z is an integer ranging from 1 to the number of hydroxy groups on the polyol and D is a polyol residue. Also disclosed are processes for the preparation of these polyol esters, a tanning composition comprising a metallic salt and a polyol ester, and a method of tanning using said composition.

Abstract translation: PCT No.PCT / AU92 / 00154 Sec。 371日期：1993年10月7日 102（e）日期1994年1月18日PCT提交1992年4月9日PCT公布。 出版物WO92 / 18456 具有式（Para）和/或（Meta）和/或（Ortho）的多元羧酸的有机多羟基酯，其中R 6为 - （COOR 1）x或（I）1R 7为H; 或R6和R7一起用于（II）; R1和R2是氢或-OR1，-OR2一起形成酸酐（-O-）键; x是0或1的整数; Z是多元醇上1至数个羟基的整数，D是多元醇残基。 还公开了制备这些多元醇酯的方法，包含金属盐和多元醇酯的鞣制组合物以及使用所述组合物进行鞣制的方法。

公开(公告)号：US4381406A

公开(公告)日：1983-04-26

申请号：US303648

申请日：1981-09-18

Applicant: Joseph H. Finley

Inventor： Joseph H. Finley

IPC: B01J31/00 ,  B01J31/02 ,  C07B61/00 ,  C07C20060101 ,  C07C63/20 ,  C07C67/00 ,  C07C67/08 ,  C07C67/12 ,  C07C69/80 ,  C07C69/83 ,  C08F20060101

CPC classification number: C07C67/08 ,  C07C67/11

Abstract: Allylic esters of tetrachlorophthalic acid are formed using allylic alcohol both as a reactant and a solvent. In the first step, the alcohol and a base are reacted with tetrachlorophthalic anhydride to form the half-ester sodium salt. In the second step, the sodium salt is reacted with allylic halide to form the diester which crystallizes from solution. The excess solvent may be treated to recover the raw materials or recycled.

Abstract translation: 使用烯丙醇作为反应物和溶剂形成四氯邻苯二甲酸的烯丙酯。 在第一步中，使醇和碱与四氯邻苯二甲酸酐反应形成半酯钠盐。 在第二步中，钠盐与烯丙基卤化物反应形成从溶液中结晶的二酯。 可以处理过量的溶剂以回收原料或再循环。

公开(公告)号：US20160102166A1

公开(公告)日：2016-04-14

申请号：US14889809

申请日：2014-05-05

Applicant: Johnson Controls Technology Company ,  BEIJING JOHNSON CONTROLS AUTOMOTIVE COMPONENTS CO.

Inventor： Haifeng Ni ,  Jenny Dong ,  Yao Gu ,  James T. McEvoy ,  William Li

IPC: C08G18/48 ,  C08G18/72 ,  C08G18/08 ,  C07C67/26 ,  C07C67/12

CPC classification number: C08G18/4887 ,  C07C67/12 ,  C07C67/26 ,  C08G18/14 ,  C08G18/36 ,  C08G18/4288 ,  C08G18/72 ,  C08G2101/00

Abstract: Disclosed embodiments include an open cell, molded polyurethane foam comprising the reaction product of a reaction mixture comprising: an isocyanate mixture; and a polyol formulation, comprising a glycerin-initiated, alkylene-oxide capped natural oil polyol having a molecular weight of between 3,000 and 8,000 and a polydispersity index (PDI) of between approximately 1.5 and 2.5, wherein the PDI is defined as the ratio of the weight-average molecular weight, Mw, to the number-average molecular weight, Mn.

Abstract translation: 公开的实施方案包括开孔，模塑聚氨酯泡沫，其包含反应混合物的反应产物，其包含：异氰酸酯混合物; 和多元醇制剂，其包含分子量在3,000至8,000之间的甘油引发的烯化氧封端的天然油多元醇和多分散指数（PDI）在约1.5和2.5之间，其中PDI定义为 重均分子量Mw，数均分子量Mn。

公开(公告)号：US07205443B2

公开(公告)日：2007-04-17

申请号：US11041940

申请日：2005-01-26

Applicant: Takeo Komata ,  Kei Matsunaga ,  Yoshiki Hirotsu ,  Shinya Akiba

Inventor： Takeo Komata ,  Kei Matsunaga ,  Yoshiki Hirotsu ,  Shinya Akiba

IPC: C07C31/20 ,  C07C31/18 ,  C07C31/27 ,  C07C67/08 ,  C07C67/12 ,  C07C67/14

CPC classification number: C07C49/733 ,  C07C29/145 ,  C07C45/72 ,  C07C49/24 ,  C07C49/493 ,  C07C49/497 ,  C07C49/82 ,  C07C67/14 ,  C07C2601/08 ,  C07C2602/08 ,  C07C69/653 ,  C07C31/42 ,  C07C35/48 ,  C07C35/52

Abstract: A process for producing a fluorine-containing 2,4-diol represented by the formula [4], wherein R1 represents a hydrogen atom or an acyclic or cyclic alkyl group having a carbon atom number of 1 to 7; R2 represents an acyclic or cyclic alkyl group having a carbon atom number of 1 to 7; and R1 and R2 are optionally bonded to each other to form a ring, includes reducing a hydroxy ketone represented by the formula [3], wherein R1 and R2 are defined as above, by hydrogen in the presence of a ruthenium catalyst.

Abstract translation: 由式[4]表示的含氟2,4-二醇的制造方法，

公开(公告)号：US20050154209A1

公开(公告)日：2005-07-14

申请号：US10502750

申请日：2003-01-31

Applicant: Yutaka Ishii ,  Yasushi Miki ,  Yoshiro Furukawa ,  Satoshi Murakami

Inventor： Yutaka Ishii ,  Yasushi Miki ,  Yoshiro Furukawa ,  Satoshi Murakami

IPC: B01J31/02 ,  C07C51/083 ,  C07C67/12 ,  C07D453/04 ,  C07C229/02

CPC classification number: B01J31/0244 ,  B01J31/0204 ,  B01J31/0237 ,  B01J31/0271 ,  C07B2200/07 ,  C07C51/083 ,  C07C67/12 ,  C07D453/04 ,  C07C59/48

Abstract: The present invention provides a method of kinetic optical resolution of carboxylic acid derivatives using specific optically active catalysts. A racemic or diastereomeric mixture of carboxylic acid derivatives of the formula (A) is reacted with a nucleophile in the presence of an optically active catalyst to form an optically active nucleophile derivative of the formula (B). The catalyst is an optically active compound represented by the formula (C) or (D) [wherein R1 is a substituted or unsubstituted, saturated or unsaturated, straight-chain, branched or alicyclic aliphatic hydrocarbon group which can have a heteroatom, R2 is ethyl or vinyl, and R5 is hydrogen or methoxy respectively].

Abstract translation: 本发明提供使用特定光学活性催化剂的羧酸衍生物的动态光学拆分方法。 式（A）的羧酸衍生物的外消旋或非对映异构体混合物在光学活性催化剂存在下与亲核试剂反应以形成式（B）的光学活性亲核体衍生物。 催化剂是由式（C）或（D）表示的光学活性化合物[其中R 1是取代或未取代的饱和或不饱和的直链，支链或脂环族脂族烃基，其中 可以具有杂原子，R 2是乙基或乙烯基，R 5分别是氢或甲氧基）。

公开(公告)号：US20050010062A1

公开(公告)日：2005-01-13

申请号：US10618367

申请日：2003-07-10

Applicant: Mark Dewis ,  Michelle Huber

Inventor： Mark Dewis ,  Michelle Huber

IPC: A23L1/226 ,  A61K8/36 ,  A61K8/37 ,  A61K8/42 ,  A61K8/49 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  C07C51/16 ,  C07C51/295 ,  C07C57/03 ,  C07C67/12 ,  C07C69/587 ,  C07C69/96 ,  C07C233/09 ,  C07C233/02 ,  C07D317/44

CPC classification number: A61K8/361 ,  A23L27/2026 ,  A23L27/2054 ,  A61K8/37 ,  A61K8/42 ,  A61K8/4973 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  C07C51/16 ,  C07C51/295 ,  C07C57/03 ,  C07C67/12 ,  C07C69/587 ,  C07C69/96 ,  C07C233/09

Abstract: Described is a genus of E2,E4,Z8-undecatrienoic acid derivatives defined according to the structure: wherein Z represents —OR″ or —NRR′ with the provisos that when Z is —OR″, R″ is hydrogen, C1-C6 straight chain or branched-chain alkyl or C3-C6 straight chain or branched-chain alkenyl; and when Z is —NRR′, R represents, in the alternative, hydrogen, methyl or ethyl and R′ represents methyl, ethyl, n-propyl, cyclopropyl, isopropyl, n-butyl, sec-butyl, isobutyl, 2-methylbutyl, cyclobutyl, cyclopentyl or allyl. The E2,E4,Z8-undecatrienoic acid derivatives are useful in imparting, augmenting and/or enhancing flavors, aromas and somatosensory effects in or to consumable materials such as foods, beverages, skin care products, oral care products, medicinal products and the like. Also described is a synthesis process for producing such derivatives.

Abstract translation: 描述了根据以下结构定义的E2，E4，Z8-十一碳烯酸衍生物属：其中Z表示-OR“或-NRR'，条件是当Z为-OR”时，R“为氢，C1 -C6直链或支链烷基或C3-C6直链或支链烯基; 当Z是-NRR'时，R代表氢，甲基或乙基，R'代表甲基，乙基，正丙基，环丙基，异丙基，正丁基，仲丁基，异丁基，2-甲基丁基， 环丁基，环戊基或烯丙基。 E2，E4，Z8-十一碳三烯酸衍生物可用于赋予，增强和/或增强食用，饮料，护肤品，口腔护理产品，药用产品等中的消耗材料中的香料，香气和体感效应 。 还描述了制备这种衍生物的合成方法。

公开(公告)号：US5756830A

公开(公告)日：1998-05-26

申请号：US766441

申请日：1996-12-12

Applicant: Christopher M. Nielsen ,  Anantha Sudhakar

Inventor： Christopher M. Nielsen ,  Anantha Sudhakar

IPC: C07C69/63 ,  C12P7/62 ,  C12P41/00 ,  C07C67/00 ,  C07C67/12

CPC classification number: C12P41/004 ,  C07C69/63 ,  C12P7/62

Abstract: A process for producing a crystalline chiral hydroxy ester of the formula: ##STR1## is disclosed. The process comprises reacting a diol of the formula: ##STR2## with an effective amount of isobutryic anhydride and an effective amount of a lipase enzyme in an effective amount of acetonitrile, said reaction being conducted at a low temperature, and wherein X.sup.1 and X.sup.2 are each independently selected from F or Cl.

Abstract translation: 公开了一种制备下式的结晶手性羟基酯的方法：（IMAG）（1.0）。 该方法包括使下式的二醇与有效量的异丁酸酐和有效量的脂肪酶在有效量的乙腈中反应，所述反应在低温下进行，其中X1 和X 2各自独立地选自F或Cl。