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    Modular stent graft employing bifurcated graft and leg locking stent elements
    2.
    发明申请
    Modular stent graft employing bifurcated graft and leg locking stent elements 失效
    模块化支架移植使用分叉移植和腿部锁定支架元件

    公开(公告)号：US20060178733A1

    公开(公告)日：2006-08-10

    申请号：US11336175

    申请日：2006-01-20

    申请人： Leonard Pinchuk ,  Arthur Rosenthal

    发明人： Leonard Pinchuk ,  Arthur Rosenthal

    IPC分类号： A61F2/06

    CPC分类号： A61F2/07 ,  A61F2/89 ,  A61F2/91 ,  A61F2002/061 ,  A61F2002/067 ,  A61F2002/075 ,  A61F2230/0054

    摘要： A modular stent graft system and associated surgical methods are provided that incorporates an external stent-based locking mechanism to prevent disarticulation of the legs from the bifurcated graft as well as other features that overcome many of the difficulties of the prior art associated with delivering and securing the bifurcated grafts to the intended deployment site within the human aorta.

    摘要翻译： 提供了一种组合式支架移植系统和相关的手术方法，其包括外部基于支架的锁定机构，以防止腿部从分叉移植物脱位，以及克服与递送和固定有关的现有技术的许多困难的其它特征 分叉移植到人类主动脉内的预期部署地点。

    Stretch valve balloon catheter and methods for producing and using same
    4.
    发明授权
    Stretch valve balloon catheter and methods for producing and using same 有权
    弹力气囊导管及其制造和使用方法

    公开(公告)号：US09272120B2

    公开(公告)日：2016-03-01

    申请号：US14024151

    申请日：2013-09-11

    申请人： Leonard Pinchuk ,  Gary A. Kalser ,  Gregory L. Mayback ,  James Leone

    发明人： Leonard Pinchuk ,  Gary A. Kalser ,  Gregory L. Mayback ,  James Leone

    IPC分类号： A61M31/00 ,  A61M37/00 ,  A61M27/00 ,  A61M25/00 ,  A61M25/10

    CPC分类号： A61M25/0017 ,  A61M25/04 ,  A61M25/10 ,  A61M25/1018 ,  A61M25/10186 ,  A61M25/1027 ,  A61M2025/1093 ,  A61M2210/1085

    摘要： A safety catheter for draining a given fluid includes a hollow stretch valve and a flexible, multi-lumen, balloon drainage catheter having a proximal catheter end, a balloon defining a balloon interior to be inflated with an inflation fluid, a drain lumen. and a balloon drainage port fluidically connecting the balloon interior to the drain lumen. The hollow stretch valve is shaped to permit the given fluid to pass therethrough and is positioned in the drain lumen to at least partially slide therein such that, in a steady state, the stretch valve prevents the inflation fluid from passing through the drainage port, and, in a stretched state when the proximal catheter end is stretched, the distal sliding portion slides within the drain lumen to permit the inflation fluid to pass through the drainage port and into the drain lumen.

    摘要翻译： 用于排出给定流体的安全导管包括中空拉伸阀和具有近端导管末端的柔性多腔气囊排出导管，气囊限定用充气流体充气的气囊内部，排液腔。 以及将气囊内部流体连接到排泄管腔的气囊引流口。 中空拉伸阀被成形为允许给定的流体通过，并且定位在排水管腔中以在其中至少部分地滑动，使得在稳定状态下，拉伸阀阻止膨胀流体通过排水口，并且 当拉伸近端导管末端时处于拉伸状态，远端滑动部分在排水管内滑动，以使膨胀流体通过排水口并进入排水管腔。

    Stretch Valve Balloon Catheter and Methods for Producing and Using Same
    6.
    发明申请
    Stretch Valve Balloon Catheter and Methods for Producing and Using Same 有权
    伸展阀气球导管及其生产和使用方法

    公开(公告)号：US20130237966A1

    公开(公告)日：2013-09-12

    申请号：US13868376

    申请日：2013-04-23

    申请人： Leonard Pinchuk ,  Gary A. Kalser ,  Gregory L. Mayback ,  James Leone

    发明人： Leonard Pinchuk ,  Gary A. Kalser ,  Gregory L. Mayback ,  James Leone

    IPC分类号： A61M25/00

    CPC分类号： A61M25/0017 ,  A61B5/205 ,  A61M25/04 ,  A61M25/10181 ,  A61M25/10184 ,  A61M25/10185 ,  A61M2025/1093 ,  A61M2210/1085

    摘要： A safety catheter includes a flexible, multi-lumen shaft having an outer diameter, a distal tip, a proximal catheter end with a drain end and a proximal inflation end. The multi-lumen shaft defines a drain lumen, a distal hollow balloon portion, at least one inflation lumen, and a drainage port. A hollow stretch valve is coaxially disposed in the drainage lumen and has a radially self-expandable proximal section fixedly connected within the drain lumen by self-expansion, a flexible intermediate section longitudinally movable within the drain lumen, and a distal plug movably positioned in the drain lumen to prevent fluid from passing through the drainage port in a steady state and being slidably disposed within the drain lumen such that, in a stretched state when the proximal catheter end is stretched, the distal plug slides within the drain lumen to permit the inflation fluid to pass through the drainage port.

    摘要翻译： 安全导管包括具有外径，远侧末端，具有排水端和近侧充气端的近侧导管端的柔性多腔轴。 多腔轴限定排水腔，远端中空球囊部分，至少一个充气腔和排水口。 中空拉伸阀同轴地布置在排水腔中，并且具有通过自膨胀固定地连接在排水管腔内的径向自扩张近端部分，可在排液腔内纵向移动的柔性中间部分和可移动地定位在排液腔内的远端塞 排水管腔，以防止流体在稳定状态下通过排水口并且可滑动地设置在排水管腔内，使得当拉伸近端导管端时处于拉伸状态，远端塞在排液管内滑动以允许膨胀 流体通过排水口。

    Method, Surgical Kit and Device for Treating Glaucoma
    7.
    发明申请
    Method, Surgical Kit and Device for Treating Glaucoma 有权
    方法，手术套件和治疗青光眼的装置

    公开(公告)号：US20130184631A1

    公开(公告)日：2013-07-18

    申请号：US13348931

    申请日：2012-01-12

    申请人： Leonard Pinchuk

    发明人： Leonard Pinchuk

    IPC分类号： A61F9/007

    CPC分类号： A61F9/00781 ,  A61F9/0017 ,  A61F9/007 ,  A61F9/00736 ,  A61F2009/00891 ,  A61M27/002 ,  A61M2210/0612

    摘要： A surgical kit includes at least one instrument and at least one implant device. The instrument has a needle body used to form a surgical passage through ocular tissue. The device includes a flexible tube that defines a duct for diverting aqueous humor with an outer surface having a maximal cross-sectional dimension that is less than the maximal cross-sectional dimension of the needle body. The device incorporates sealing means including at least one element that define a maximal cross-sectional dimension that is greater that the maximal cross-sectional dimension of the needle body and that are operably disposed within the surgical passage and form a seal between the surrounding ocular tissue and the element(s) as well as fixate the device in the surgical passage. The kit (and devices thereof) can be used as part of a surgical method to divert aqueous humor to a space formed in ocular tissue.

    摘要翻译： 手术套件包括至少一个仪器和至少一个植入装置。 仪器具有用于通过眼组织形成手术通道的针体。 该装置包括柔性管，其限定用于将房水转移到具有小于针体的最大横截面尺寸的最大横截面尺寸的外表面的管道。 该装置包括密封装置，其包括至少一个元件，其限定最大横截面尺寸，其大于针体的最大横截面尺寸并且可操作地设置在手术通道内并在周围的眼组织之间形成密封 和元件以及将装置固定在手术通道中。 该套件（及其装置）可用作手术方法的一部分，以将房水转移到眼组织中形成的空间。

    Pacemaker Lead and Method of Making Same
    9.
    发明申请
    Pacemaker Lead and Method of Making Same 失效
    起搏器牵头及其制作方法

    公开(公告)号：US20100241208A1

    公开(公告)日：2010-09-23

    申请号：US12690997

    申请日：2010-01-21

    申请人： Leonard Pinchuk

    发明人： Leonard Pinchuk

    IPC分类号： A61N1/05

    CPC分类号： A61N1/05 ,  A61B5/042 ,  A61B2562/125

    摘要： An improved pacemaker lead including a lead body supporting at least one flexible conductor element that provides an electrical signal path between a proximal connector element and a distal electrode. The lead body includes an insulating structure that protects the flexible conductor element(s) wherein the insulating structure is realized from a polymer blend of a thermoplastic polyurethane elastomer and an isobutylene block copolymer. The mole fraction of the isobutylene block copolymer of the polymer blend is in the range of 2-15% (most preferably on the order of 10%). The polymer blend of the insulating structure has a maximum tensile strength in the range of 20-40 MPa (most preferably in a range of 25-35 MPa). In the preferred embodiment, the hardness of the polymer blend can be characterized by a Shore hardness in a range of 70-80 A. The flexible conductor element(s) preferably include a coiled wire conductor defining a central axis with an outer surface facing radially outward away from the central axis and an inner surface facing radially inward toward the central axis, and the insulating structure surrounds at least the outer surface of the coiled wire conductor (and more preferably encapsulates the coiled wire conductor). The polymer blend of the insulating structure has reduced oxygen permeability, and thus provides improved resistance to environmental stress cracking and metal ion induced oxidation while maintaining the flexibility and desired tensile strength of the lead body.

    摘要翻译： 一种改进的起搏器引线，包括引导体，其支撑至少一个柔性导体元件，其提供近端连接器元件和远端电极之间的电信号路径。 引线体包括保护柔性导体元件的绝缘结构，其中由热塑性聚氨酯弹性体和异丁烯嵌段共聚物的聚合物共混物实现绝缘结构。 聚合物共混物的异丁烯嵌段共聚物的摩尔分数在2-15％（最优选约10％）的范围内。 绝缘结构的聚合物共混物的最大拉伸强度在20-40MPa的范围内（最优选在25-35MPa的范围内）。 在优选实施方案中，聚合物共混物的硬度可以通过肖氏硬度在70-80A的范围内表征。柔性导体元件优选包括限定中心轴线的线圈状导体，其外表面面向径向 远离中心轴线的外表面和朝向中心轴线径向向内的内表面，并且绝缘结构至少围绕线圈导线的外表面（更优选地包围线圈导线）。 绝缘结构的聚合物共混物具有降低的透氧性，从而提供改善的耐环境应力开裂性和金属离子诱导氧化性，同时保持引线体的柔软性和所需拉伸强度。

    APPARATUS, METHODS AND DEVICES FOR TREATMENT OF OCULAR DISORDERS
    10.
    发明申请
    APPARATUS, METHODS AND DEVICES FOR TREATMENT OF OCULAR DISORDERS 审中-公开
    用于治疗眼病的装置，方法和装置

    公开(公告)号：US20100241046A1

    公开(公告)日：2010-09-23

    申请号：US12440096

    申请日：2007-09-06

    申请人： Leonard Pinchuk ,  Jean-Marie A. Parel ,  Francisco Fantes

    发明人： Leonard Pinchuk ,  Jean-Marie A. Parel ,  Francisco Fantes

    IPC分类号： A61M1/00

    CPC分类号： A61L27/56 ,  A61F9/00781 ,  A61L27/48 ,  A61L31/129 ,  A61L31/146 ,  C08L53/02

    摘要： Apparatus and methods for relieving and treating glaucoma and other ocular disorders are disclosed. The apparatus includes a thin flexible membrane and preferably a tubular member. In another aspect of the invention, a surgical device for repairing ocular tissue includes a flexible membrane of a polymeric material comprising polyisobutylene. In the preferred embodiment, the polymeric material of the membrane is porous.

    摘要翻译： 公开了用于缓解和治疗青光眼和其它眼部疾病的装置和方法。 该装置包括薄的柔性膜并且优选地为管状构件。 在本发明的另一方面，用于修复眼组织的手术装置包括包含聚异丁烯的聚合物材料的柔性膜。 在优选的实施方案中，膜的聚合物材料是多孔的。