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公开(公告)号：US20130243877A1
公开(公告)日：2013-09-19
申请号：US13685274
申请日：2012-11-26
Applicant: Michael Haley , Dennis Hubbard, JR. , Keith Rosiello
Inventor： Michael Haley , Dennis Hubbard, JR. , Keith Rosiello
CPC classification number: A61K35/16 , A61K9/14 , A61K9/16 , A61K9/1682 , B01D1/18 , B01D1/20 , G01N33/49
Abstract: The technology relates to spray dried plasma and methods of making the same. The method includes providing plasma to a spray drying apparatus, spray drying the plasma, at the spray drying apparatus, to form physiologically active plasma power, the spray drying apparatus configured utilizing one or more parameters, and storing the physiologically active plasma powder.
Abstract translation: 该技术涉及喷雾干燥的等离子体及其制备方法。 该方法包括在喷雾干燥装置处将等离子体提供给喷雾干燥装置，喷雾干燥等离子体，以形成生理活性的等离子体动力，所述喷雾干燥装置利用一个或多个参数配置并储存生理活性的等离子体粉末。
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公开(公告)号：US20070142773A1
公开(公告)日：2007-06-21
申请号：US10552354
申请日：2004-05-03
Applicant: Keith Rosiello , Douglas Clibourn , Howard Donnelly , G.L. Henderson
Inventor： Keith Rosiello , Douglas Clibourn , Howard Donnelly , G.L. Henderson
IPC: A61F7/12
CPC classification number: A61F7/0085 , A61M1/369 , A61M5/44 , A61M2205/3368 , A61M2205/3633 , A61M2205/3653 , A61M2205/8206
Abstract: The invention is directed generally to a method and system for controlling the temperature of a fluid, i.e., warming or cooling a fluid, and more particularly, to a method and system for warming a fluid to be delivered to the body of a patient. In a preferred embodiment, a method and system for warming a fluid to be delivered into the body of a patient is provided and may include a controller and a fluid delivery-line. The fluid delivery-line may include an insulative tube and a fluid delivery tube positioned within the first tube and for communicating a fluid from a source to a destination. The fluid delivery-line may also include at least one thermal sensor positioned proximate the fluid delivery tube, a heating element positioned proximate the fluid delivery tube and a thermal medium positioned between the first tube and the second tube.
Abstract translation: 本发明一般涉及一种用于控制流体温度，即加热或冷却流体的方法和系统，更具体地说，涉及一种用于加热待输送到患者身体的流体的方法和系统。 在优选实施例中，提供了一种用于加热要输送到患者体内的流体的方法和系统，并且可以包括控制器和流体输送管线。 流体输送管线可以包括绝缘管和定位在第一管内的流体输送管，并用于将流体从源传送到目的地。 流体输送管线还可以包括邻近流体输送管定位的至少一个热传感器，位于流体输送管附近的加热元件和位于第一管和第二管之间的热介质。
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公开(公告)号：US20050113237A1
公开(公告)日：2005-05-26
申请号：US10723499
申请日：2003-11-25
Applicant: Keith Rosiello , William de Quevedo , Keith Boudreau
Inventor： Keith Rosiello , William de Quevedo , Keith Boudreau
CPC classification number: B04B5/0428 , A61M1/0209 , A61M1/3693 , A61M1/3696
Abstract: The present invention is directed to a processing/expressor chamber/bag and/or hub assembly for use in centrifugal processing, in particular, to centrifuge blood processing. Accordingly, such a bag according to some embodiments of the present invention may include a substantially circular enclosure having a central opening, where the central opening includes an integrally formed first mating portion. The hub may include a second mating portion corresponding to the first mating portion. Other embodiments may include methods of assembling the hub and bag, and use of such a bag in a centrifuge system.
Abstract translation: 本发明涉及一种用于离心处理，特别是离心血液处理的加工/表达室/袋和/或轮毂组件。 因此，根据本发明的一些实施例的这种袋子可以包括具有中心开口的基本圆形的外壳，其中中心开口包括整体形成的第一配合部分。 毂可以包括对应于第一配合部分的第二配合部分。 其他实施例可以包括组装轮毂和袋的方法，以及在离心机系统中使用这种袋。
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公开(公告)号：US20050032618A1
公开(公告)日：2005-02-10
申请号：US10633842
申请日：2003-08-04
Applicant: Keith Rosiello
Inventor： Keith Rosiello
CPC classification number: B04B5/0428 , A61M1/0209 , A61M1/3693 , A61M1/3696 , A61M1/3698
Abstract: A flexible processing and/or expressor chamber for a biological cell processing apparatus is provided which may include a first side and a second side and having a expandable wall, wherein a first end of the expandable wall is attached to a circumference of the first side of the flexible chamber and a second end of the expandable wall is attached to a circumference of the second side of the flexible chamber. Either or both sides of the chamber may include an axial opening.
Abstract translation: 提供了一种用于生物细胞处理装置的柔性处理和/或表达室，其可以包括第一侧和第二侧并且具有可膨胀壁，其中可扩张壁的第一端附接到第一侧的圆周 柔性室和可膨胀壁的第二端附接到柔性室的第二侧的圆周上。 腔室的任一侧或两侧可包括轴向开口。
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公开(公告)号：US20120225044A9
公开(公告)日：2012-09-06
申请号：US12089132
申请日：2006-10-16
Applicant: Keith Rosiello , Henrik Clausen , Hans H. Wandall
Inventor： Keith Rosiello , Henrik Clausen , Hans H. Wandall
CPC classification number: A01N1/0221 , A61K31/70 , A61K35/19 , G01N33/86 , G01N2800/222 , G01N2800/224
Abstract: The present invention provides modified platelets having a reduced platelet clearance and methods for reducing platelet clearance. Also provided are compositions for the preservation of platelets. The invention also provides methods for making a pharmaceutical composition containing the modified platelets and for administering the pharmaceutical composition to a mammal to mediate hemostasis.
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Patent Agency Ranking
公开(公告)号：US20120107791A1
公开(公告)日：2012-05-03
申请号：US13291402
申请日：2011-11-08
Applicant: Keith Rosiello , Henrik Clausen
Inventor： Keith Rosiello , Henrik Clausen
IPC: A01N1/02
CPC classification number: A01N1/0226 , A01N1/00 , A01N1/02
Abstract: The present invention provides modified platelets having a reduced platelet clearance and methods for reducing platelet clearance. Also provided are compositions for the preservation of platelets. The invention also provides methods for making a pharmaceutical composition containing the modified platelets and for administering the pharmaceutical composition to a mammal to mediate hemostasis.
Abstract translation: 本发明提供具有降低的血小板清除率的改良血小板和减少血小板清除率的方法。 还提供了用于保存血小板的组合物。 本发明还提供了制备含有改性血小板的药物组合物和用于将哺乳动物给药以介导止血的方法。
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公开(公告)号：US08052667B2
公开(公告)日：2011-11-08
申请号：US11574857
申请日：2005-09-07
Applicant: Keith Rosiello , Henrik Clausen
Inventor： Keith Rosiello , Henrik Clausen
CPC classification number: A01N1/0226 , A01N1/00 , A01N1/02
Abstract: The present invention provides modified platelets having a reduced platelet clearance and methods for reducing platelet clearance. Also provided are compositions for the preservation of platelets. The invention also provides methods for making a pharmaceutical composition containing the modified platelets and for administering the pharmaceutical composition to a mammal to mediate hemostasis.
Abstract translation: 本发明提供具有降低的血小板清除率的改良血小板和减少血小板清除率的方法。 还提供了用于保存血小板的组合物。 本发明还提供了制备含有改性血小板的药物组合物和用于将哺乳动物给药以介导止血的方法。
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公开(公告)号：US20100108183A1
公开(公告)日：2010-05-06
申请号：US12684525
申请日：2010-01-08
Applicant: Keith Rosiello
Inventor： Keith Rosiello
IPC: B65B3/12
CPC classification number: A61M1/02 , A61M1/0209 , A61M1/0277 , A61M1/367 , A61M1/3693 , Y10S383/906
Abstract: A system for transferring blood product between a blood storage bag and a processing bag. The system includes an airtight containment chamber for supporting therein one or more blood storage bags. A door is provided for access to the chamber and there is included an airtight fixture that allows tubing from the blood storage bag to exit the chamber. A fluid pump is coupled to the containment chamber for establishing either pressure or vacuum within the containment chamber. A controller controls the air pump to, in turn, control the transfer of a blood product.
Abstract translation: 一种用于在血液存储袋和处理袋之间转运血液制品的系统。 该系统包括用于在其中支撑一个或多个血液储存袋的气密容纳室。 设有一个用于进入腔室的门，并且包括一个气密夹具，其允许血液储存袋的管路离开腔室。 流体泵联接到容纳室，用于在容纳室内建立压力或真空。 控制器控制气泵，进而控制血液制品的转移。
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公开(公告)号：US20050243056A1
公开(公告)日：2005-11-03
申请号：US11082109
申请日：2005-03-15
Applicant: Daryl Afshin , Keith Rosiello
Inventor： Daryl Afshin , Keith Rosiello
CPC classification number: G06F3/0219 , G06F1/1616 , G06F1/1632 , G06F1/169
Abstract: A portable (or laptop) computer that includes the novel user-input device. The user input controls a variety of interface and media applications commonly found on portable computer systems. The novel input device detaches to facilitate remote operation or compact storage. Device includes user-interface hardware and manual controls for pointer, video, internet, and gaming control applications, eliminating the need for auxiliary input devices.
Abstract translation: 包括新颖的用户输入设备的便携式（或膝上型）计算机。 用户输入控制便携式计算机系统上常见的各种接口和媒体应用。 新颖的输入装置分离以便于远程操作或紧凑的存储。 设备包括用于指针，视频，互联网和游戏控制应用的用户界面硬件和手动控制，不需要辅助输入设备。
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公开(公告)号：US20050121458A1
公开(公告)日：2005-06-09
申请号：US10953914
申请日：2004-09-29
Applicant: Keith Rosiello
Inventor： Keith Rosiello
CPC classification number: A47K5/1202 , A47K2005/1218
Abstract: The disclosed invention provides an apparatus for dispensing liquids held by containers that are located at positions distal to the dispenser. The disclosed invention includes a dispenser, container, universal cap, and conduit assembly with coupling device. The coupling device provides the ability to attach the conduit to typical dispenser inlets. The universal cap provides the ability for a wide variety of containers to be connected to the dispenser.
Abstract translation: 所公开的发明提供了一种用于分配由容器保持的液体的装置，其位于远离分配器的位置处。 所公开的发明包括具有联接装置的分配器，容器，通用盖和导管组件。 联接装置提供将导管连接到典型的分配器入口的能力。 通用盖提供了将各种容器连接到分配器的能力。
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