公开(公告)号：US20050113237A1

公开(公告)日：2005-05-26

申请号：US10723499

申请日：2003-11-25

Applicant: Keith Rosiello ,  William de Quevedo ,  Keith Boudreau

Inventor： Keith Rosiello ,  William de Quevedo ,  Keith Boudreau

IPC: A61M1/36 ,  B04B5/04 ,  B04B7/12

CPC classification number: B04B5/0428 ,  A61M1/0209 ,  A61M1/3693 ,  A61M1/3696

Abstract: The present invention is directed to a processing/expressor chamber/bag and/or hub assembly for use in centrifugal processing, in particular, to centrifuge blood processing. Accordingly, such a bag according to some embodiments of the present invention may include a substantially circular enclosure having a central opening, where the central opening includes an integrally formed first mating portion. The hub may include a second mating portion corresponding to the first mating portion. Other embodiments may include methods of assembling the hub and bag, and use of such a bag in a centrifuge system.

Abstract translation: 本发明涉及一种用于离心处理，特别是离心血液处理的加工/表达室/袋和/或轮毂组件。 因此，根据本发明的一些实施例的这种袋子可以包括具有中心开口的基本圆形的外壳，其中中心开口包括整体形成的第一配合部分。 毂可以包括对应于第一配合部分的第二配合部分。 其他实施例可以包括组装轮毂和袋的方法，以及在离心机系统中使用这种袋。

公开(公告)号：US20120271324A1

公开(公告)日：2012-10-25

申请号：US13392826

申请日：2010-08-26

Applicant: John V. Yannone ,  Christopher Petroff ,  Keith Boudreau

Inventor： John V. Yannone ,  Christopher Petroff ,  Keith Boudreau

IPC: A61B17/04 ,  H05B3/02

CPC classification number: H05B3/262 ,  A61B17/0483 ,  A61B17/0487 ,  A61B17/06166 ,  A61B2017/0619 ,  H05B2203/013 ,  H05B2203/017

Abstract: A heating element with dimensions less than a centimetre according to an embodiment of the present invention includes a metallic substrate (1) which includes a material having a thermal conductivity greater than 5 W/m·k and an ultimate tensile strength measured at ambient temperature greater than 400 MPa and which includes a working face suitable to be placed in contact with a medium or an element to be heated, a conductive layer (3) which is supported by a face of the substrate opposite the working face and which forms a circuit comprising two power supply elements (A) linked by a thin resistive element (R) and adapted to be connected to a current source, and a dielectric layer (2) interposed between the conductive layer (3) and the metallic substrate (1).

Abstract translation: 根据本发明的实施例的尺寸小于一厘米的加热元件包括金属基底（1），其包括导热率大于5W / m·k的材料，并且在环境温度下测量的极限拉伸强度更大 其包括适于与介质或待加热元件接触的工作面，由与工作面相对的基板的表面支撑并形成电路的导电层（3），该电路包括 由薄电阻元件（R）连接并适于连接到电流源的两个电源元件（A）和介于导电层（3）和金属基板（1）之间的电介质层（2）。

公开(公告)号：US20090191174A1

公开(公告)日：2009-07-30

申请号：US11995421

申请日：2006-07-26

Applicant: Keith Boudreau ,  Dan Morgan ,  Mike Haley ,  Will Garcia De Quevedo

Inventor： Keith Boudreau ,  Dan Morgan ,  Mike Haley ,  Will Garcia De Quevedo

IPC: A61K35/12 ,  C12M1/00 ,  C12N5/00 ,  A61P37/00

CPC classification number: A61M1/3693 ,  A61M1/3696 ,  A61M1/3698 ,  A61M2205/12 ,  B04B5/0428 ,  B04B5/0442 ,  B04B7/02

Abstract: The present invention is directed to an environmentally closed cell processing device, for the aseptic processing of blood cells. The device includes a continuous flow centrifuge, fluid reservoirs and fluid handling systems. Blood cells are processed by the present device, to remove their immunodominant antigens. Seroconverted cells and methods of treating subjects with these cells are also described.

Abstract translation: 本发明涉及一种用于血细胞无菌处理的环境细胞处理装置。 该装置包括连续流离心机，流体储存器和流体处理系统。 血细胞由本发明装置处理，以除去其免疫显性抗原。 还描述了血清转染的细胞和用这些细胞治疗受试者的方法。

公开(公告)号：US20090182353A1

公开(公告)日：2009-07-16

申请号：US12192758

申请日：2008-08-15

Applicant: Douglas Snell ,  Keith Boudreau ,  Daniel McCormick ,  Dan Morgan ,  Francis P. Harrington ,  Paul Westhaver ,  David Marro ,  John Yannone ,  Philip Hui ,  Thomas Egan

Inventor： Douglas Snell ,  Keith Boudreau ,  Daniel McCormick ,  Dan Morgan ,  Francis P. Harrington ,  Paul Westhaver ,  David Marro ,  John Yannone ,  Philip Hui ,  Thomas Egan

IPC: A61B17/10

CPC classification number: A61B17/06166 ,  A61B17/0487 ,  A61B2017/00734 ,  A61B2017/0619 ,  B29C65/224 ,  B29C65/228 ,  B29C65/38 ,  B29C66/69 ,  B29C66/8122 ,  B29C66/91213 ,  B29C66/91231 ,  B29C66/91317 ,  B29C66/91421 ,  B29C66/91423 ,  B29C66/91655 ,  B29L2031/753 ,  H05B3/06 ,  H05B3/265 ,  H05B2203/013

Abstract: A method of suture welding is disclosed which includes: receiving suture segments between first and second jaw members, the first and second jaw members being in an open state. closing the first and second jaw members to captively hold and position the suture segments between the first and second jaw members; selectively applying an elongated joiner element to the suture segments where the joiner element has a selectively operative heating element facing the suture segments; and applying energy to the heating element to weld the suture segments-to-be-welded, whereby the heating element has a temperature above a predetermined threshold adapted to at least partially melt the suture segments.

Abstract translation: 公开了一种缝合焊接方法，其包括：在第一和第二钳口构件之间接收缝合线段，第一和第二钳口构件处于打开状态。 闭合第一和第二钳口构件以将缝合线段夹持并定位在第一和第二钳口构件之间; 选择性地将细长的接合元件施加到缝合线段，其中接合元件具有面向缝合线段的选择性操作的加热元件; 以及向所述加热元件施加能量以焊接待焊接的所述缝合线段，由此所述加热元件具有适于至少部分地熔化所述缝合线段的预定阈值以上的温度。