-
公开(公告)号:US11633171B2
公开(公告)日:2023-04-25
申请号:US17860314
申请日:2022-07-08
摘要: The present invention relates to an ultrasound-based system for localizing a medical device within the field of view of an ultrasound imaging probe. A localization system is provided that includes at least three ultrasound emitters that are arranged on a frame; and a position triangulation unit. The frame is adapted for attachment to an ultrasound imaging probe. The position triangulation unit determines a spatial position of the ultrasound detector relative to the at least three ultrasound emitters based on signals received from an ultrasound detector that is attached to the medical device. The frame includes a detachable reference volume comprising a background volume and an inclusion or void. When the detachable reference volume is attached to the frame and the frame is attached to the ultrasound imaging probe the inclusion or void provides a corresponding image feature within the field of view of the ultrasound imaging probe for use in calibrating the field of view of the ultrasound imaging probe with the coordinate system of the localization system.
-
公开(公告)号:US12004899B2
公开(公告)日:2024-06-11
申请号:US17842416
申请日:2022-06-16
CPC分类号: A61B8/0841 , A61B5/066 , A61B8/12 , A61B8/4245 , A61B8/445 , A61B8/4477 , A61B8/463 , A61B8/483 , G06T11/003 , A61B8/469
摘要: The present invention relates to a system for indicating a position of an interventional device feature (11a) of an interventional device (11) respective an image plane (12) defined by an ultrasound imaging probe (18) of a beamforming ultrasound imaging system (15) in which the position of the interventional device feature (11a) is determined based on ultrasound signals transmitted between the ultrasound imaging probe (18) and an ultrasound transducer (16) attached to the interventional device at a predetermined distance (Lp) from the interventional device feature (11a). An icon providing unit (IPU) provides a first icon (Cde) indicative of a circular zone with a radius corresponding to the predetermined distance (Lp). The first icon (Cde) is displayed in a fused image that includes a reconstructed ultrasound image (RUI) from the beamforming ultrasound imaging system.
-
公开(公告)号:US11986339B2
公开(公告)日:2024-05-21
申请号:US17266599
申请日:2019-08-02
发明人: Mischa Megens , Hendrik Roelof Stapert , Mustafa Hakan Gokgurler , Stefan Van De Pas , Jeroen Kortsmit , Franciscus Hendrikus Van Heesch , Harm Jan Willem Belt , Ameet Kumar Jain , Kunal Vaidya
CPC分类号: A61B8/0841 , A61B8/12 , A61B8/4245 , A61B8/4477 , A61B8/4483 , A61B8/5207 , A61B2017/3413
摘要: System (10) for determining a position of an interventional device (11) respective an image plane (12) defined by an ultrasound imaging probe (13). The position is determined based on ultrasound signals transmitted between the ultrasound imaging probe (13) and an ultrasound transducer (15) attached to the interventional device (11). An image reconstruction unit (IRU) provides a reconstructed ultrasound image (RUI). A position determination unit (PDU) computes a lateral position (LAPTOFSmax, θIPA) of the ultrasound transducer (15) respective the image plane (12) based on a time of flight (TOFSmax) of a maximum detected intensity (ISmax) ultrasound signal. The position determination unit (PDU) also computes an out-of-plane distance (Dop) between the ultrasound transducer (15) and the image plane (12). Computing the out-of-plane distance (Dop) involves comparing the maximum detected intensity (ISmax) with a model (MO) describing an expected variation of in-plane maximum detected intensity (ISmaxInplane) with time of flight.
-
公开(公告)号:US11413011B2
公开(公告)日:2022-08-16
申请号:US16063858
申请日:2016-12-13
摘要: The present invention relates to an ultrasound-based system for localizing a medical device within the field of view of an ultrasound imaging probe. A localization system is provided that includes at least three ultrasound emitters that are arranged on a frame; and a position triangulation unit. The frame is adapted for attachment to an ultrasound imaging probe. The position triangulation unit determines a spatial position of the ultrasound detector relative to the at least three ultrasound emitters based on signals received from an ultrasound detector that is attached to the medical device. The frame includes a detachable reference volume comprising a background volume and an inclusion or void. When the detachable reference volume is attached to the frame and the frame is attached to the ultrasound imaging probe the inclusion or void provides a corresponding image feature within the field of view of the ultrasound imaging probe for use in calibrating the field of view of the ultrasound imaging probe with the coordinate system of the localization system.
-
公开(公告)号:US11497563B2
公开(公告)日:2022-11-15
申请号:US17059811
申请日:2019-06-06
发明人: Ramon Quido Erkamp , Hendrik Roelof Stapert , Gunther Lamparter , Ameet Kumar Jain , Alvin Chen , Shyam Bharat , Kunal Vaidya , Francois Guy Gerard Marie Vignon
摘要: A controller (240/340) for simultaneously tracking multiple interventional medical devices includes a memory (242/342) that stores instructions and a processor (241/341) that executes the instructions. When executed by the processor (241/341), the instructions cause the controller to execute a process that includes receiving timing information from a first signal emitted from an ultrasound probe (252/352) and reflective of timing when the ultrasound probe (252/352) transmits ultrasound beams to generate ultrasound imagery. The process executed by the controller also includes forwarding the timing information to be available for use by a first acquisition electronic component (232/332). The first acquisition electronic component (232/332) also receives sensor information from a first passive ultrasound sensor (S1) on a first interventional medical device (212/312). The timing information is used to synchronize the sensor information from the first passive ultrasound sensor (S1) on the first interventional medical device (212/312) with sensor information from a second passive ultrasound sensor (S2) on a second interventional medical device (216/316).
-
公开(公告)号:US11464584B2
公开(公告)日:2022-10-11
申请号:US16970974
申请日:2019-02-03
发明人: Willem-Jan Arend De Wijs , Cornelis Gerardus Visser , Hendrik Roelof Stapert , Johannes Wilhelmus Weekamp , Gerardus Franciscus Cornelis Maria Lijten , Eric Franciscus Johannes Claessens
IPC分类号: A61B34/20 , A61B8/08 , A61M25/01 , H01L41/047 , H01L41/113 , A61B90/00 , A61B8/00
摘要: An interventional device includes an elongate shaft and a transducer strip. The transducer strip includes a first edge and an opposing second edge. The first edge and the second edge are separated by a width dimension, and the first edge and the second edge each extend along a length direction of the transducer strip. The transducer strip also includes a piezoelectric transducer that extends along a transducer direction that forms an acute angle with respect to the length direction. The transducer strip is wrapped in the form of a spiral around the elongate shaft of the interventional device such that the piezoelectric transducer forms a band around the elongate shaft. The width dimension is defined such that the adjacent first and second edges of consecutive turns of the spiral abut or overlap one another.
-
公开(公告)号:US11369340B2
公开(公告)日:2022-06-28
申请号:US16337230
申请日:2017-09-29
摘要: The present invention relates to a system for indicating a position of an interventional device feature (11a) of an interventional device (11) respective an image plane (12) defined by an ultrasound imaging probe (18) of a beamforming ultrasound imaging system (15) in which the position of the interventional device feature (11a) is determined based on ultrasound signals transmitted between the ultrasound imaging probe (18) and an ultrasound transducer (16) attached to the interventional device at a predetermined distance (Lp) from the interventional device feature (11a). An icon providing unit (IPU) provides a first icon (Cde) indicative of a circular zone with a radius corresponding to the predetermined distance (Lp). The first icon (Cde) is displayed in a fused image that includes a reconstructed ultrasound image (RUI) from the beamforming ultrasound imaging system.
-
公开(公告)号:US11275150B2
公开(公告)日:2022-03-15
申请号:US15778715
申请日:2016-12-02
IPC分类号: G01S5/30 , A61B8/08 , G01S15/89 , A61B34/20 , A61B90/00 , A61B8/12 , G01S7/52 , A61B8/00 , A61B17/34 , A61B90/96 , A61B90/98
摘要: The present invention relates to an apparatus (10) for tracking a position of an interventional device (11) respective an image plane (12) of an ultrasound field. The position includes an out-of-plane distance (Dop). A geometry-providing unit (GPU) includes a plurality of transducer-to-distal-end lengths (Ltde1 . . . n), each length corresponding to a predetermined distance (Ltde) between a distal end (17, 47) of an interventional device (11, 41) and an ultrasound detector (16, 46) attached to the interventional device, for each of a plurality of interventional device types (T1 . . . N). An image fusion unit (IFU) receives data indicative of the type (T) of the interventional device being tracked; and based on the type (T): selects from the geometry-providing unit (GPU), a corresponding transducer-to-distal-end length (Ltde); and indicates in a reconstructed ultrasound image (RUI) both the out-of-plane distance (Dop) and the transducer-to-distal-end length (Ltde) for the interventional device within the ultrasound field.
-
公开(公告)号:US10670589B2
公开(公告)日:2020-06-02
申请号:US15710887
申请日:2017-09-21
发明人: Maarten Marinus Johannes Wilhelmus Van Herpen , Derk Jan Wilfred Klunder , Hendrik Roelof Stapert
摘要: The invention relates to detection the presence of a target molecule in a sample, wherein the sample is contacted with a substrate, the substrate subsequently being washed in a wash step. In particular, the invention relates to a method of detecting the presence of a target molecule in a sample, the method comprising: (a) contacting the sample (37) with a substrate having immobilized thereon probe molecules that specifically binds to the target molecule; (b) washing the substrate (38) in a wash step by a wash fluid in order to remove or dilute unbound target molecules; (c) detect the presence of resultant binding complexes (39) on the substrate to determine whether the target molecule is present in the sample—The wash fluid being substantially refractive index matched to the substrate.
-
公开(公告)号:US11872075B2
公开(公告)日:2024-01-16
申请号:US17265618
申请日:2019-08-07
发明人: Mischa Megens , Hendrik Roelof Stapert , Mustafa Hakan Gokgurler , Stefan Van De Pas , Jeroen Kortsmit , Franciscus Hendrikus Van Heesch , Harm Jan Willem Belt , Ameet Kumar Jain , Kunal Vaidya , Francois Guy Gerard Marie Vignon
CPC分类号: A61B8/0841 , A61B8/12 , A61B8/5207 , A61B2034/2063 , A61B2090/3782
摘要: System (10) for determining a position of an interventional device (11) respective an image plane (12) defined by an ultrasound imaging probe (13). The position is determined based on ultrasound signals transmitted between the ultrasound imaging probe (13) and an ultrasound transducer (15) attached to the interventional device (11). An image reconstruction unit (IRU) provides a reconstructed ultrasound image (RUI). A position determination unit (PDU) computes a position (LAPTOFSmax, θIPA) of the ultrasound transducer (15) respective the image plane (12). The position determination unit (PDU) indicates the computed position (LAPTOFSmax, θIPA) in the reconstructed ultrasound image (RUI). The position determination unit (PDU) suppresses the indication of the computed position (LAPTOFSmax, θIPA) under specified conditions relating to the computed position (LAPTOFSmax, θIPA) and the ultrasound signals.
-
-
-
-
-
-
-
-
-