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公开(公告)号：US11571180B2
公开(公告)日：2023-02-07
申请号：US16469363
申请日：2017-12-18
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Bernardus Hendrikus Wilhelmus Hendriks , Drazenko Babic , Jarich Willem Spliethoff , Torre Michelle Bydlon , Grzegorz Andrzej Toporek , Aleksandra Popovic , Christian Reich
Abstract: A system may generally comprise a tracking device, an ultrasound device and a processing unit. A position and orientation of the ultrasound device may be traceable by the tracking device. The processing unit may be configured (i) to receive 3D information of a region of interest in relation to a marker, with both the region of interest and the marker being located within a body, (ii) to determine the position of the marker relative to the ultrasound device based on an ultrasound image of the body including the marker, and (iii) to determine the position and orientation of the ultrasound device relative to the tracking device. The system may further comprise a visualization device and the processing unit may further be configured to generate a visualization of the region of interest in relation to an outer surface of the body.
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公开(公告)号：US10094768B2
公开(公告)日：2018-10-09
申请号：US15301898
申请日：2015-04-07
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Klaas Cornelis Jan Wijbrans , Gerhardus Wilhelmus Lucassen , Bernardus Hendrikus Wilhelmus Hendriks , Christian Reich , Johannes Antonius Van Rooij , Jaap Knoester
Abstract: The present invention relates to an optical fiber connector for mating a first group of one or more optical fibers (102) with one or more corresponding optical fibers in a second group of one or more optical fibers (103). The optical fiber connector includes a shutter (105), which prevents the ingress of debris into the connector, and provides an optical reference surface with which to calibrate optical fibers that are inserted into the connector. The optical fiber connector finds application in the general optical fiber field, and more particularly finds application in the medical field in which it may be used to connect optical fibers in a photonic needle application.
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公开(公告)号：US12089821B2
公开(公告)日：2024-09-17
申请号：US17637830
申请日：2020-08-28
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Bernardus Hendrikus Wilhelmus Hendriks , Drazenko Babic , Jarich Willem Spliethoff , Gerhardus Wilhelmus Lucassen , Joanneke Gerrigje Groen , Christian Reich , Ronaldus Frederik Johannes Holthuizen , Robert Johannes Frederik Homan
CPC classification number: A61B1/317 , A61B1/00126 , A61B1/00165 , A61B5/0075 , A61B5/4504 , A61B5/6878 , A61B17/848 , A61B17/8897 , A61B2017/922
Abstract: An orthopedic pin (100) for optically analyzing a bone region (110) includes an elongate shaft (101) and at least one optical fiber (105). The elongate shaft has a circular outer cross section with a first diameter (D1), a distal end (102) for insertion into bone, a proximal end (103), and an optical connector portion (104) disposed towards the proximal end (103). The at least one optical fiber (105) extends within the elongate shaft (101) between the optical connector portion (104), and the distal end (102) for transmitting optical radiation between the optical connector portion (104) and the bone region (110) when the distal end (102) is inserted into the bone region (110). The optical connector portion (104) comprises a reduced-diameter portion (106). The reduced-diameter portion (106) extends along at least a portion of the elongate shaft (101), and has an outer cross section comprising a width (Drd) perpendicularly with respect to the elongate shaft (101). The width (Drd) is less than the first diameter (D1).
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公开(公告)号：US10143450B2
公开(公告)日：2018-12-04
申请号：US14436207
申请日：2013-10-28
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Waltherus Cornelis Jozef Bierhoff , Christian Reich , Martinus Bernardus Van Der Mark , Bernardus Hendrikus Wilhelmus Hendriks , Anja Van De Stolpe , Stephan Voss , Axel Winkel , Marjolen Van Der Voort , Vishnu Vardhan Pully , Gerhardus Wilhelmus Lucassen , Susanne Dorien Van Den Berg-Dams , Jarich Willem Spliethoff
IPC: A61B10/04 , A61B1/015 , A61B10/00 , A61B1/00 , A61B5/00 , A61B10/02 , A61B5/145 , A61B5/1455 , A61B5/1459
Abstract: A biopsy device includes a tubular member, a hollow shaft and an elongated fiber body having at least one optical fiber. The hollow shaft has a laterally (sidewardly) facing notch in its distal portion. The tubular member is movable relative to the shaft, between a first position in which the notch is covered by the tubular member, and a second position in which the notch is not covered by the tubular member. The shaft is movable between a first position in which the distal end of the optical fiber is located at the distal end of the shaft with the elongated fiber body extending through the notch, and a second position in which the distal end of the at least one optical fiber is located proximally to the notch.
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公开(公告)号：US20180303468A1
公开(公告)日：2018-10-25
申请号：US16018140
申请日：2018-06-26
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Waltherus Cornelis Jozef Bierhoff , Christian Reich , Martinus Bernardus Van Der Mark , Bernardus Hendrikus Wilhelmus Hendriks , Anja Van De Stolpe , Stephan Voss , Axel Winkel , Marjolen Van Der Voort , Vishnu Vardhan Pully , Gerhardus Wilhelmus Lucassen , Susanne Dorien Van Den Berg-Dams , Jarich Willem Spliethoff
IPC: A61B10/04 , A61B5/1455 , A61B1/015 , A61B5/00 , A61B10/02 , A61B10/00 , A61B5/1459 , A61B1/00 , A61B5/145
CPC classification number: A61B10/04 , A61B1/00165 , A61B1/015 , A61B5/0071 , A61B5/0073 , A61B5/0075 , A61B5/0084 , A61B5/14503 , A61B5/14546 , A61B5/14552 , A61B5/14556 , A61B5/1459 , A61B5/6848 , A61B10/0096 , A61B10/0275 , A61B2010/045 , A61B2560/0475 , A61B2560/0487
Abstract: A biopsy device is provided comprising a tubular member, a hollow shaft and an elongated fiber body. The hollow shaft may have a distal end and a shaft, wherein a laterally (sidewardly) facing notch is formed in the distal portion of the shaft. The elongated fiber body may include at least one optical fiber, preferably at least two optical fibers, with a distal end. The tubular member is movable relative to the shaft, between a first position in which the notch is covered by the tubular member, and a second position in which the notch is not covered by the tubular member. The fiber body is movable within the shaft, between a first position in which the distal end of the optical fiber is located at the distal end of the shaft with the elongated fiber body extending through the notch, and a second position in which the distal end of the at least one optical fiber is located proximally to the notch.
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Patent Agency Ranking
公开(公告)号：US09867599B2
公开(公告)日：2018-01-16
申请号：US14762526
申请日：2013-10-16
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Bernardus Hendrikus Wilhelmus Hendriks , Christian Reich , Waltherus Cornelis Jozef Bierhoff , Manfred Mueller , Franciscus Marinus Antonius Maria Van Gaal , Jozef Christiaan Mathieu Versleegers , Vishnu Vardhan Pully , Sven Stoffelen
CPC classification number: A61B10/04 , A61B5/0075 , A61B5/0084 , A61B5/6848 , A61B10/0041 , A61B10/0275 , A61B10/0283 , A61B17/3403 , A61B2010/0225 , A61B2010/045 , A61B2017/00057 , A61B2017/00199 , A61B2017/008 , A61B2017/00907 , A61B2017/320064 , A61B2505/05 , A61B2562/0233
Abstract: An interventional device, e.g. a Vacuum Assisted Biopsy (VAB) needle, incorporating optical fibers such that biological tissue in a volume at a side of the interventional device can be substantially completely optically probed by optical spectroscopy. In a VAB embodiment, a plurality of optical fiber pairs connected to respective optical ports, are placed at opposite positions along the suction cavity, and they are readout subsequently allowing to make a map of the tissue properties along the place where the tissue will be cut by the VAB needle. Based on decision software in an optical console, it can be determined whether the tissue present in the cutting cavity is completely normal tissue or not, prior to actually performing the biopsy on the tissue. In this way a well defined end point for VAB is created. In one embodiment, the optical fibers are arranged in a wall structure of a thin sleeve which fits onto existing VAB needles, thus allowing the VAB needle to be upgraded with an optical probing capability.
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公开(公告)号：US20150359525A1
公开(公告)日：2015-12-17
申请号：US14762526
申请日：2013-10-16
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Bernardus Hendrikus Wilhelmus Hendriks , Christian Reich , Waltherus Cornelis Jozef Bierhoff , Manfred Mueller , Franciscus Marinus Antonius Maria Van Gaal , Jozef Christiaan Mathieu Versleegers , Vishnu Vardhan Pully , Sven STOFFELEN
CPC classification number: A61B10/04 , A61B5/0075 , A61B5/0084 , A61B5/6848 , A61B10/0041 , A61B10/0275 , A61B10/0283 , A61B17/3403 , A61B2010/0225 , A61B2010/045 , A61B2017/00057 , A61B2017/00199 , A61B2017/008 , A61B2017/00907 , A61B2017/320064 , A61B2505/05 , A61B2562/0233
Abstract: An interventional device, e.g. a Vacuum Assisted Biopsy (VAB) needle, incorporating optical fibers such that biological tissue in a volume at a side of the interventional device can be substantially completely optically probed by optical spectroscopy. In a VAB embodiment, a plurality of optical fiber pairs connected to respective optical ports, are placed at opposite positions along the suction cavity, and they are readout subsequently allowing to make a map of the tissue properties along the place where the tissue will be cut by the VAB needle. Based on decision software in an optical console, it can be determined whether the tissue present in the cutting cavity is completely normal tissue or not, prior to actually performing the biopsy on the tissue. In this way a well defined end point for VAB is created. In one embodiment, the optical fibers are arranged in a wall structure of a thin sleeve which fits onto existing VAB needles, thus allowing the VAB needle to be upgraded with an optical probing capability.
Abstract translation: 介入装置，例如 真空辅助活组织检查（VAB）针，其包括光纤，使得介入装置侧面的体积中的生物组织可以通过光学光谱学被基本上完全光学探测。 在VAB实施例中，连接到相应光学端口的多个光纤对被放置在沿着吸入腔的相对位置处，并且随后读出它们，使得能够沿着组织被切割的位置形成组织性质的图 由VAB针。 基于光学控制台中的判定软件，可以在实际对组织进行活组织检查之前，确定存在于切割腔中的组织是否完全正常组织。 以这种方式，创建了一个明确定义的VAB端点。 在一个实施例中，光纤被布置在薄套管的壁结构中，该薄套管适合现有的VAB针，从而允许VAB针头以光学探测能力升级。
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8.发明申请SYSTEM WITH PHOTONIC BIOPSY DEVICE FOR OBTAINING PATHOLOGICAL INFORMATION 审中-公开具有用于获得病理信息的光子生物装置的系统公开(公告)号：US20150265256A1
公开(公告)日：2015-09-24
申请号：US14436207
申请日：2013-10-28
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Waltherus Cornelis Jozef Bierhoff , Christian Reich , Martinus Bernardus Van Der Mark , Bernardus Hendrikus Wilhelmus Hendriks , Anja Van De Stolpe , Stephan Voss , Axel Winkel , Marjolen Van Der Voort , Vishnu Vardhan Pully , Gerhardus Wilhelmus Lucassen , Susanne Dorien Van Den Berg-Dams , Jarich Willem Spliethoff
CPC classification number: A61B10/04 , A61B1/00165 , A61B1/015 , A61B5/0071 , A61B5/0073 , A61B5/0075 , A61B5/0084 , A61B5/14503 , A61B5/14546 , A61B5/14552 , A61B5/14556 , A61B5/1459 , A61B5/6848 , A61B10/0096 , A61B10/0275 , A61B2010/045 , A61B2560/0475 , A61B2560/0487
Abstract: A biopsy device is provided comprising a tubular member, a hollow shaft and an elongated fiber body. The hollow shaft may have a distal end and a shaft, wherein a laterally (sidewardly) facing notch is formed in the distal portion of the shaft. The elongated fiber body may include at least one optical fiber, preferably at least two optical fibers, with a distal end. The tubular member is movable relative to the shaft, between a first position in which the notch is covered by the tubular member, and a second position in which the notch is not covered by the tubular member. The fiber body is movable within the shaft, between a first position in which the distal end of the optical fiber is located at the distal end of the shaft with the elongated fiber body extending through the notch, and a second position in which the distal end of the at least one optical fiber is located proximally to the notch.
Abstract translation: 提供活检装置，其包括管状构件，空心轴和细长纤维体。 空心轴可以具有远端和轴，其中在轴的远侧部分中形成有侧向（侧向）的切口。 细长纤维体可以包括具有远端的至少一根光纤，优选至少两根光纤。 所述管状构件可相对于所述轴移动，在所述凹口被所述管状构件覆盖的第一位置和所述凹口未被所述管状构件覆盖的第二位置之间。 所述纤维体可在所述轴内在所述光纤的远端位于所述轴的远端的第一位置和所述细长纤维体延伸穿过所述切口之间移动;以及第二位置，所述远端 的至少一个光纤位于切口的近侧。
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公开(公告)号：US12251172B2
公开(公告)日：2025-03-18
申请号：US18270533
申请日：2021-12-28
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Ronaldus Frederik Johannes Holthuizen , Robert Johannes Frederik Homan , Jarich Willem Spliethoff , Bernardus Hendrikus Wilhelmus Hendriks , Peter George Van De Haar , Johanneke Gerrigje Groen , Jan Rongen , Edward Vuurberg , Johan Juliana Dries , Christian Reich , Keshav Simhadri
Abstract: The present invention relates to guidance during a medical intervention. In order to provide an improved navigation support with a facilitated setup, a system (10) for navigation support is provided. An image data input (12) receives a plurality of acquired 2D X-ray images of a subject's body from different angles. A set of markers, which are visible in X-ray images and which are detectable by a navigation system, is assigned to the subject. A marker detecting arrangement (16) is provided that detects a current spatial location of the markers assigned to the subject. A data processor (14) reconstructs a 3D volume of the subject based on the plurality of 2D X-ray images. At least a part of the markers is arranged outside the volume covered by the reconstructed 3D volume of the subject, while the markers are visible in the 2D X-ray images. The data processor (14) identifies the markers in the 2D X-ray images based on image data of the plurality of 2D X-ray images outside the 3D volume and determines a spatial location of the markers in relation to the 3D volume of the subject. The data processor (14) also registers the reconstructed 3D volume of the subject to a current spatial position of the subject based on the detected current spatial location of the markers and the determined spatial location of the markers in relation to the 3D volume of the subject. An output interface (18) provides the registered reconstructed 3D volume for navigation.
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公开(公告)号：US11406367B2
公开(公告)日：2022-08-09
申请号：US16018140
申请日：2018-06-26
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Waltherus Cornelis Jozef Bierhoff , Christian Reich , Martinus Bernardus Van Der Mark , Bernardus Hendrikus Wilhelmus Hendriks , Anja Van De Stolpe , Stephan Voss , Axel Winkel , Marjolein Van Der Voort , Vishnu Vardhan Pully , Gerhardus Wilhelmus Lucassen , Susanne Dorien Van Den Berg-Dams , Jarich Willem Spliethoff
IPC: A61B10/04 , A61B5/00 , A61B10/02 , A61B5/145 , A61B5/1455 , A61B5/1459 , A61B1/00 , A61B1/015 , A61B10/00
Abstract: A biopsy device is provided comprising a tubular member, a hollow shaft and an elongated fiber body. The hollow shaft may have a distal end and a shaft, wherein a laterally (sidewardly) facing notch is formed in the distal portion of the shaft. The elongated fiber body may include at least one optical fiber, preferably at least two optical fibers, with a distal end. The tubular member is movable relative to the shaft, between a first position in which the notch is covered by the tubular member, and a second position in which the notch is not covered by the tubular member. The fiber body is movable within the shaft, between a first position in which the distal end of the optical fiber is located at the distal end of the shaft with the elongated fiber body extending through the notch, and a second position in which the distal end of the at least one optical fiber is located proximally to the notch.
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