公开(公告)号：US20180256914A1

公开(公告)日：2018-09-13

申请号：US15745827

申请日：2016-07-21

Applicant: KLOX TECHNOLOGIES INC.

Inventor： Lise HÉBERT ,  Michel CIMON ,  David OHAYON ,  Nikolaos LOUPIS ,  Remigio PIERGALLINI

IPC: A61N5/06 ,  A61K41/00

CPC classification number: A61N5/062 ,  A61K9/006 ,  A61K31/352 ,  A61K33/40 ,  A61K41/0057 ,  A61K45/06 ,  A61N2005/0606 ,  A61N2005/0609 ,  A61N2005/0656 ,  A61N2005/0663 ,  Y02A50/473 ,  A61K2300/00

Abstract: The present disclosure provides compositions and methods for treating mucositis associated with treatment-induced neutropenia in a patient. The methods comprise applying a biophotonic composition comprising a fluorescent dye and a carrier to mucosal lesions and subsequently exposing the composition to actinic light.

公开(公告)号：US20210228720A1

公开(公告)日：2021-07-29

申请号：US15734599

申请日：2019-06-05

Applicant: KLOX TECHNOLOGIES INC.

Inventor： David OHAYON ,  Carlo BELLINI ,  Jason GUGLIUZZA ,  Nikolaos LOUPIS ,  Remigio PIERGALLINI ,  Abdellatif CHENITE

IPC: A61K41/00 ,  A61F13/00 ,  A61L15/24 ,  A61L15/26 ,  A61L15/42 ,  A61N5/06 ,  C09K11/02 ,  C09K11/06

Abstract: The present technology generally relates to an absorbent biophotonic fiber system and to articles comprising the absorbent biophotonic fiber system as well as to the potential uses thereof, such as, for example, in wound treatment.

公开(公告)号：US20200085625A1

公开(公告)日：2020-03-19

申请号：US16610568

申请日：2018-05-04

Applicant: KLOX TECHNOLOGIES INC.

Inventor： Carlo BELLINI ,  Nikolaos LOUPIS ,  Remigio PIERGALLINI ,  David OHAYON

IPC: A61F13/00 ,  A61N5/06

Abstract: The present technology generally relates to products, devices, methods and systems for healing of wounds or for wound-treatment therapies. More particularly, but not by way of limitation, the present technology relates an absorbent product impregnated with photoactivatable agents, or light-absorbing molecules, as photoactivatable inserts as wound dressing that can be used together as part of negative-pressure wound therapy (NPWT) system or separately and without the NPWT system.

公开(公告)号：US20220111050A1

公开(公告)日：2022-04-14

申请号：US17557205

申请日：2021-12-21

Applicant: KLOX TECHNOLOGIES INC.

Inventor： Remigio PIERGALLINI ,  Nikolaos LOUPIS ,  David OHAYON ,  Kevin WILKINSON ,  Giovanni SCAPAGNINI

IPC: A61K41/00 ,  A61K9/00 ,  A61K31/365 ,  A61N5/06 ,  A61P31/00 ,  A61P31/04 ,  A61P31/10

Abstract: The present document describes methods of using compositions for inhibiting biofilm formation, or disrupting existing or developing biofilms in a subject, which composition comprises at least one chromophore and a pharmacologically acceptable carrier.

公开(公告)号：US20190209683A1

公开(公告)日：2019-07-11

申请号：US16333873

申请日：2017-09-22

Applicant: KLOX TECHNOLOGIES INC.

Inventor： Remigio PIERGALLINI ,  Nikolaos LOUPIS ,  David OHAYON ,  Kevin WILKINSON ,  Giovanni SCAPAGNINI

IPC: A61K41/00 ,  A61K31/365 ,  A61K9/00 ,  A61P31/04

CPC classification number: A61K41/00 ,  A61K9/0014 ,  A61K31/365 ,  A61N5/06 ,  A61N5/062 ,  A61N5/0624 ,  A61N2005/0661 ,  A61P31/00 ,  A61P31/04 ,  A61P31/10

Abstract: The present document describes methods of using compositions for inhibiting biofilm formation, or disrupting existing or developing biofilms in a subject, which composition comprises at least one chromophore and a pharmacologically acceptable carrier.

公开(公告)号：US20170362744A1

公开(公告)日：2017-12-21

申请号：US15523283

申请日：2015-10-30

Applicant: KLOX TECHNOLOGIES INC.

Inventor： Remigio PIERGALLINI ,  Nikolaos LOUPIS ,  David OHAYON

IPC: D01F1/10 ,  C09K11/06 ,  A61N5/06 ,  D06P1/00 ,  C09K11/02

CPC classification number: D01F1/106 ,  A61N5/0616 ,  A61N5/062 ,  A61N2005/063 ,  A61N2005/0645 ,  A61N2005/0651 ,  A61N2005/0659 ,  A61N2005/0662 ,  C09K11/02 ,  C09K11/06 ,  C09K2211/1018 ,  D06P1/0012

Abstract: In various aspects, the present disclosure relates to fibers and fabric media comprising photoactivatable agents and to fibers and fabric media that are photoactivatable by photoactivation of the photoactivatable agents. In some instances, the fibers and the fabric media have photoactivatable agents present on their surface (e.g., the fiber/fabric is coated or sprayed with the photoactivatable agents or the fiber/fabric is dipped into a composition or a formulation comprising the photoactivatable agent). In other instances, the photoactivatable agents are incorporated into the materials making the fibers (e.g., the photoactivatable agents are mixed/compounded with the materials making the fibers). The photoactivatable fibers of the present disclosure comprise at least one thermoplastic polymer and at least photoactivatable agent that absorbs and emits light between about 400 nm and about 800 nm.